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29838-67-3,MFCD01632717
Catalog No.:AA00BBQ6

29838-67-3 | Astilbin

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1mg
97%
in stock  
$7.00   $5.00
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5mg
97%
in stock  
$17.00   $12.00
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10mg
97%
in stock  
$28.00   $20.00
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25mg
97%
in stock  
$44.00   $31.00
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100mg
97%
in stock  
$93.00   $65.00
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250mg
97%
in stock  
$139.00   $97.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BBQ6
Chemical Name:
Astilbin
CAS Number:
29838-67-3
Molecular Formula:
C21H22O11
Molecular Weight:
450.3928
MDL Number:
MFCD01632717
SMILES:
Oc1cc(O)c2c(c1)O[C@@H]([C@H](C2=O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)c1ccc(c(c1)O)O
Properties
Computed Properties
 
Complexity:
676  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
3  
XLogP3:
0.4  

Literature

Title: Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180401

Title: Astilbin inhibits proliferation of rat aortic smooth muscle cells induced by angiotensin II and down-regulates expression of protooncogene.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120401

Title: Cytotoxic and antimicrobial aporphine alkaloids from Fissistigma poilanei (Annonaceae) collected in Vietnam.

Journal: Natural product research 20120101

Title: Chemical constituents of Bauhinia aurea.

Journal: Journal of Asian natural products research 20120101

Title: Astilbin attenuates hyperuricemia and ameliorates nephropathy in fructose-induced hyperuricemic rats.

Journal: Planta medica 20111101

Title: Optimized self-microemulsifying drug delivery systems (SMEDDS) for enhanced oral bioavailability of astilbin.

Journal: Die Pharmazie 20111001

Title: Effects of genistein, apigenin, quercetin, rutin and astilbin on serum uric acid levels and xanthine oxidase activities in normal and hyperuricemic mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

Title: Herbal medicines and infectious diseases: characterization by LC-SPE-NMR of some medicinal plant extracts used against malaria.

Journal: Planta medica 20110701

Title: Isolation and characterization of two flavonoids, engeletin and astilbin, from the leaves of Engelhardia roxburghiana and their potential anti-inflammatory properties.

Journal: Journal of agricultural and food chemistry 20110511

Title: Astilbin suppresses acute heart allograft rejection by inhibiting maturation and function of dendritic cells in mice.

Journal: Transplantation proceedings 20101101

Title: [Effects of astilbin on the expression of TNF alpha and IL-10 in liver warm ischemia-reperfusion injury].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100601

Title: Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular).

Journal: Journal of natural products 20100528

Title: ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100401

Title: [Chemical constituents from Sarcandra glabra].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100301

Title: [Effects of astilbin on maturation and immunologic function of mouse bone marrow-derived dendritic cells].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20100201

Title: Inhibition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae).

Journal: Biological research 20100101

Title: Effect of astilbin on experimental diabetic nephropathy in vivo and in vitro.

Journal: Planta medica 20091101

Title: [Separation and purification of total flavonoids in Smilax glabra by polyamide resins].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091001

Title: Permeation of astilbin and taxifolin in Caco-2 cell and their effects on the P-gp.

Journal: International journal of pharmaceutics 20090813

Title: [Protective effects of astilbin on renal ischemia-reperfusion injury in rats].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090801

Title: Validation and application of an LC-ESI-MS method for simultaneous determination of astilbin and its major metabolite 3'-O-methylastilbin in rat plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090615

Title: Structural revision of two flavanonol glycosides from Smilax glabra.

Journal: Planta medica 20090501

Title: The inhibitory effect of astilbin on the arteriosclerosis of murine thoracic aorta transplant.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090401

Title: Astilbin inhibits the adhesion of T lymphocytes via decreasing TNF-alpha and its associated MMP-9 activity and CD44 expression.

Journal: International immunopharmacology 20081001

Title: [Chemical constituents in the leave of Rhizophora stylosa L and their biological activities].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080901

Title: Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines.

Journal: Chemico-biological interactions 20080110

Title: Inhibitors of aldose reductase and advanced glycation end-products formation from the leaves of Stelechocarpus cauliflorus R.E. Fr.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801

Title: [Dihydroflavonol glycosides and flavan-3-ols from Bauhinia aurea].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

Title: Identification of a new metabolite of astilbin, 3'-O-methylastilbin, and its immunosuppressive activity against contact dermatitis.

Journal: Clinical chemistry 20070301

Title: In vitro antimicrobial activity of the leaf extract of Harungana madagascariensis Lam. Ex Poir. (Hypericaceae) against strains causing otitis externa in dogs and cats.

Journal: Acta veterinaria Hungarica 20070301

Title: Effects of Astilbe thunbergii rhizomes on wound healing Part 1. Isolation of promotional effectors from Astilbe thunbergii rhizomes on burn wound healing.

Journal: Journal of ethnopharmacology 20070103

Title: Hopeaphenol: the first resveratrol tetramer in wines from North Africa.

Journal: Journal of agricultural and food chemistry 20061213

Title: Isolation and in vitro antibacterial activity of astilbin, the bioactive flavanone from the leaves of Harungana madagascariensis Lam. ex Poir. (Hypericaceae).

Journal: Journal of ethnopharmacology 20060630

Title: Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.

Journal: Organic & biomolecular chemistry 20060621

Title: Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A.

Journal: The Journal of allergy and clinical immunology 20051201

Title: Phenolic constituents with inhibitory activity against NFAT transcription from Desmos chinensis.

Journal: Archives of pharmacal research 20051201

Title: Purification of astilbin and isoastilbin in the extract of smilax glabra rhizome by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20050603

Title: [Studies on dihydroflavonol glycosides from rhizome of Smilax glabra].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040901

Title: Quantitative determination of astilbin in rabbit plasma by liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615

Title: Astilbin prevents concanavalin A-induced liver injury by reducing TNF-alpha production and T lymphocytes adhesion.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: Astilbin suppresses collagen-induced arthritis via the dysfunction of lymphocytes.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030801

Title: Astilbin suppresses delayed-type hypersensitivity by inhibiting lymphocyte migration.

Journal: The Journal of pharmacy and pharmacology 20030501

Title: Biological activity of astilbin from Dimorphandra mollis against Anticarsia gemmatalis and Spodoptera frugiperda.

Journal: Pest management science 20020501

Title: Levels of stilbene oligomers and astilbin in French varietal wines and in grapes during noble rot development.

Journal: Journal of agricultural and food chemistry 20020327

Title: Astilbin selectively facilitates the apoptosis of interleukin-2-dependent phytohemagglutinin-activated Jurkat cells.

Journal: Pharmacological research 20010801

Title: The in vitro inhibitory effect of flavonoid astilbin on 3-hydroxy-3-methylglutaryl coenzyme A reductase on Vero cells.

Journal: Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010701

Title: Wang SW, et al. Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation. Food Chem Toxicol. 2018 Apr;114:227-236.

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