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307-24-4,MFCD00198040
Catalog No.:AA0030X7

307-24-4 | Perfluorohexanoic acid

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10g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0030X7
Chemical Name:
Perfluorohexanoic acid
CAS Number:
307-24-4
Molecular Formula:
C6HF11O2
Molecular Weight:
314.0534
MDL Number:
MFCD00198040
SMILES:
OC(=O)C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F
NSC Number:
5213
Properties
Properties
 
BP:
143°C at 760 mmHg  
Form:
Solid  
MP:
14 °C  
Refractive Index:
n20/D 1.301  
Solubility:
water: insoluble  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
368  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
3.6  

Literature

Title: Perfluoroalkylated substances (PFAS) affect neither estrogen and androgen receptor activity nor steroidogenesis in human cells in vitro.

Journal: Toxicology letters 20180701

Title: Identification of protein tyrosine phosphatase SHP-2 as a new target of perfluoroalkyl acids in HepG2 cells.

Journal: Archives of toxicology 20170401

Title: Poly- and perfluorinated compounds activate human pregnane X receptor.

Journal: Toxicology 20170401

Title: Binding interactions of perfluoroalkyl substances with thyroid hormone transport proteins and potential toxicological implications.

Journal: Toxicology 20160729

Title: Perfluorocarbons and Gilbert syndrome (phenotype) in the C8 Health Study Population.

Journal: Environmental research 20141101

Title: Evaluating the additivity of perfluoroalkyl acids in binary combinations on peroxisome proliferator-activated receptor-α activation.

Journal: Toxicology 20140227

Title: Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes.

Journal: Toxicology 20130607

Title: In vitro toxicological characterization of perfluorinated carboxylic acids with different carbon chain lengths.

Journal: Toxicology letters 20130412

Title: Biodefluorination and biotransformation of fluorotelomer alcohols by two alkane-degrading Pseudomonas strains.

Journal: Biotechnology and bioengineering 20121201

Title: Dietary exposure to perfluoroalkyl acids for the Swedish population in 1999, 2005 and 2010.

Journal: Environment international 20121115

Title: Distribution and long-range transport of polyfluoroalkyl substances in the Arctic, Atlantic Ocean and Antarctic coast.

Journal: Environmental pollution (Barking, Essex : 1987) 20121101

Title: Electrochemical mineralization of perfluorocarboxylic acids (PFCAs) by ce-doped modified porous nanocrystalline PbO2 film electrode.

Journal: Environmental science & technology 20120918

Title: Ion-pair sorptive extraction of perfluorinated compounds from water with low-cost polymeric materials: polyethersulfone vs polydimethylsiloxane.

Journal: Analytica chimica acta 20120831

Title: National screening study on 10 perfluorinated compounds in raw and treated tap water in France.

Journal: Archives of environmental contamination and toxicology 20120701

Title: Temporal trends of perfluoroalkyl concentrations in American Red Cross adult blood donors, 2000-2010.

Journal: Environmental science & technology 20120605

Title: Input characterization of perfluoroalkyl substances in wastewater treatment plants: source discrimination by exploratory data analysis.

Journal: Water research 20120601

Title: Perfluoroalkyl compounds in municipal WWTPs in Tianjin, China--concentrations, distribution and mass flow.

Journal: Environmental science and pollution research international 20120601

Title: [Residue characteristics and distributions of perfluorinated compounds in surface seawater along Shenzhen coastline].

Journal: Huan jing ke xue= Huanjing kexue 20120601

Title: In ovo effects of perfluorohexane sulfonate and perfluorohexanoate on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Fate of a broad spectrum of perfluorinated compounds in soils and biota from Tierra del Fuego and Antarctica.

Journal: Environmental pollution (Barking, Essex : 1987) 20120401

Title: Transcriptional effects of perfluorinated compounds in rat hepatoma cells.

Journal: Chemosphere 20120101

Title: Determination of perfluorinated alkylated substances in sediments and sediment core from the Gulf of Gdańsk, Baltic Sea.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

Title: Occurrence, fate, and fluxes of perfluorochemicals (PFCs) in an urban catchment: Marina Reservoir, Singapore.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20120101

Title: Isomer profiles of perfluorochemicals in matched maternal, cord, and house dust samples: manufacturing sources and transplacental transfer.

Journal: Environmental health perspectives 20111101

Title: Quantitative determination of perfluorochemicals and fluorotelomer alcohols in plants from biosolid-amended fields using LC/MS/MS and GC/MS.

Journal: Environmental science & technology 20111001

Title: Investigation on per- and polyfluorinated compounds in paired samples of house dust and indoor air from Norwegian homes.

Journal: Environmental science & technology 20111001

Title: Application of WWTP biosolids and resulting perfluorinated compound contamination of surface and well water in Decatur, Alabama, USA.

Journal: Environmental science & technology 20111001

Title: Analysis of a homologous series of perfluorocarboxylates from American Red Cross adult blood donors, 2000-2001 and 2006.

Journal: Environmental science & technology 20111001

Title: Odd-numbered perfluorocarboxylates predominate over perfluorooctanoic acid in serum samples from Japan, Korea and Vietnam.

Journal: Environment international 20111001

Title: Fate of perfluorinated carboxylates and sulfonates during snowmelt within an urban watershed.

Journal: Environmental science & technology 20111001

Title: Toxicokinetics of ammonium perfluorohexanoate.

Journal: Drug and chemical toxicology 20111001

Title: Perfluorinated compounds in surface waters and WWTPs in Shenyang, China: mass flows and source analysis.

Journal: Water research 20111001

Title: Perfluorinated compounds in Haihe River and Dagu Drainage Canal in Tianjin, China.

Journal: Chemosphere 20110601

Title: Absorption, distribution, metabolism, and excretion of [1-¹⁴C]-perfluorohexanoate ([¹⁴C]-PFHx) in rats and mice.

Journal: Toxicology 20110428

Title: Effects of perfluoroalkyl compounds on mRNA expression levels of thyroid hormone-responsive genes in primary cultures of avian neuronal cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Mass flows of perfluorinated compounds (PFCs) in central wastewater treatment plants of industrial zones in Thailand.

Journal: Chemosphere 20110401

Title: Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat.

Journal: Environmental health perspectives 20110301

Title: Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110301

Title: Removal of PFOS, PFOA and other perfluoroalkyl acids at water reclamation plants in South East Queensland Australia.

Journal: Chemosphere 20110101

Title: Treatment of perfluorinated chemicals by electro-microfiltration.

Journal: Environmental science & technology 20101015

Title: Perfluorinated compounds in infiltrated river rhine water and infiltrated rainwater in coastal dunes.

Journal: Environmental science & technology 20101001

Title: Fluorotelomer ethoxylates: sources of highly fluorinated environmental contaminants part I: biotransformation.

Journal: Chemosphere 20100901

Title: Brominated flame retardants and perfluorinated compounds in indoor dust from homes and offices in Flanders, Belgium.

Journal: Chemosphere 20100901

Title: High levels of perfluorochemicals in Taiwan's wastewater treatment plants and downstream rivers pose great risk to local aquatic ecosystems.

Journal: Chemosphere 20100801

Title: Determining the molecular interactions of perfluorinated carboxylic acids with human sera and isolated human serum albumin using nuclear magnetic resonance spectroscopy.

Journal: Environmental toxicology and chemistry 20100801

Title: Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells.

Journal: Mutation research 20100719

Title: Perfluorinated compounds, polychlorinated biphenyls, and organochlorine pesticide contamination in composite food samples from Dallas, Texas, USA.

Journal: Environmental health perspectives 20100601

Title: Determination of perfluorinated compounds in the upper Mississippi river basin.

Journal: Environmental science & technology 20100601

Title: Biomonitoring perfluorinated compounds in Catalonia, Spain: concentrations and trends in human liver and milk samples.

Journal: Environmental science and pollution research international 20100301

Title: Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with different chain lengths.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100201

Title: Occurrence of perfluoroalkyl carboxylates and sulfonates in drinking water utilities and related waters from the United States.

Journal: Environmental science & technology 20091215

Title: Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats.

Journal: Toxicology letters 20091028

Title: Effects of 18 perfluoroalkyl compounds on mRNA expression in chicken embryo hepatocyte cultures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20091001

Title: Toxicological evaluation of sodium perfluorohexanoate.

Journal: Toxicology 20091001

Title: Perfluorinated alkylated substances in the aquatic environment: an Austrian case study.

Journal: Water research 20091001

Title: Perfluorinated surfactant chain-length effects on sonochemical kinetics.

Journal: The journal of physical chemistry. A 20090910

Title: Structure-activity relationships and human relevance for perfluoroalkyl acid-induced transcriptional activation of peroxisome proliferation in liver cell cultures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090901

Title: One-year follow-up of perfluorinated compounds in plasma of German residents from Arnsberg formerly exposed to PFOA-contaminated drinking water.

Journal: International journal of hygiene and environmental health 20090901

Title: A 90-day repeated dose oral (gavage) toxicity study of perfluorohexanoic acid (PFHxA) in rats (with functional observational battery and motor activity determinations).

Journal: Reproductive toxicology (Elmsford, N.Y.) 20090601

Title: Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1-sulfonic acid (PFBS) in cynomolgus monkeys and rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20090601

Title: Sonication-assisted photocatalytic decomposition of perfluorooctanoic acid.

Journal: Chemosphere 20090501

Title: 8-2 fluorotelomer alcohol aerobic soil biodegradation: pathways, metabolites, and metabolite yields.

Journal: Chemosphere 20090501

Title: Longitudinal and latitudinal distribution of perfluoroalkyl compounds in the surface water of the Atlantic Ocean.

Journal: Environmental science & technology 20090501

Title: Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems.

Journal: Environmental health perspectives 20090401

Title: Preliminary observations on perfluorinated compounds in plasma samples (1977-2004) of young German adults from an area with perfluorooctanoate-contaminated drinking water.

Journal: International journal of hygiene and environmental health 20090301

Title: Reductive defluorination of aqueous perfluorinated alkyl surfactants: effects of ionic headgroup and chain length.

Journal: The journal of physical chemistry. A 20090129

Title: Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081101

Title: Toxic effect of serial perfluorosulfonic and perfluorocarboxylic acids on the membrane system of a freshwater alga measured by flow cytometry.

Journal: Environmental toxicology and chemistry 20080701

Title: Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate-contaminated drinking water.

Journal: Environmental health perspectives 20080501

Title: Human exposure to perfluorinated chemicals through the diet: intake of perfluorinated compounds in foods from the Catalan (Spain) market.

Journal: Journal of agricultural and food chemistry 20080312

Title: Emissions of perfluorinated alkylated substances (PFAS) from point sources--identification of relevant branches.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101

Title: [Perfluorinated compounds in potable water].

Journal: Roczniki Panstwowego Zakladu Higieny 20080101

Title: Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data.

Journal: Environmental science & technology 20071115

Title: Riverine discharge of perfluorinated carboxylates from the European continent.

Journal: Environmental science & technology 20071101

Title: Perfluorinated compounds in the Pearl River and Yangtze River of China.

Journal: Chemosphere 20070801

Title: Perfluorinated compounds in some terrestrial and aquatic wildlife species from Poland.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20070501

Title: Evaluation of the acute toxicity of perfluorinated carboxylic acids using eukaryotic cell lines, bacteria and enzymatic assays.

Journal: Environmental toxicology and pharmacology 20070501

Title: [Photodegradation of perfluorinated carboxylic acids by 185 nm VUV light].

Journal: Huan jing ke xue= Huanjing kexue 20070401

Title: Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden.

Journal: Environmental health perspectives 20070201

Title: Photodegradation of perfluorooctanoic acid by 185 nm vacuum ultraviolet light.

Journal: Journal of environmental sciences (China) 20070101

Title: Fluorochemical mass flows in a municipal wastewater treatment facility.

Journal: Environmental science & technology 20061201

Title: Responses of the liver to perfluorinated fatty acids with different carbon chain length in male and female mice:in relation to induction of hepatomegaly, peroxisomal beta-oxidation and microsomal 1-acylglycerophosphocholine acyltransferase.

Journal: Biological & pharmaceutical bulletin 20060901

Title: Perfluorinated compounds in streams of the Shihwa Industrial Zone and Lake Shihwa, South Korea.

Journal: Environmental toxicology and chemistry 20060901

Title: Absorption, distribution, metabolism, and elimination of 8-2 fluorotelomer alcohol in the rat.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060601

Title: Alkaline digestion and solid phase extraction method for perfluorinated compounds in mussels and oysters from South China and Japan.

Journal: Archives of environmental contamination and toxicology 20060201

Title: Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China.

Journal: Environmental science & technology 20060201

Title: Fluorotelomer alcohol biodegradation-direct evidence that perfluorinated carbon chains breakdown.

Journal: Environmental science & technology 20051001

Title: Validation of a screening method based on liquid chromatography coupled to high-resolution mass spectrometry for analysis of perfluoroalkylated substances in biota.

Journal: Journal of chromatography. A 20050722

Title: Development of a solid-phase extraction-HPLC/single quadrupole MS method for quantification of perfluorochemicals in whole blood.

Journal: Analytical chemistry 20050201

Title: Occurrence and persistence of perfluorooctanesulfonate and other perfluorinated surfactants in groundwater at a fire-training area at Wurtsmith Air Force Base, Michigan, USA.

Journal: Journal of environmental monitoring : JEM 20030401

Title: Self-organization of amphiphilic polymer in vesicle bilayers composed of surfactant mixtures.

Journal: Biomacromolecules 20030101

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