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3081-61-6,MFCD00059653
Catalog No.:AA0031AT

3081-61-6 | L-Theanine

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Purity
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Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
25mg
98%
in stock  
$7.00   $5.00
- +
100mg
98%
in stock  
$9.00   $7.00
- +
5g
99%
in stock  
$24.00   $17.00
- +
25g
98%
in stock  
$26.00   $18.00
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100g
99%
in stock  
$81.00   $57.00
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500g
99%
in stock  
$286.00   $200.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0031AT
Chemical Name:
L-Theanine
CAS Number:
3081-61-6
Molecular Formula:
C7H14N2O3
Molecular Weight:
174.1977
MDL Number:
MFCD00059653
SMILES:
CCN[C@H](C(=O)O)CCC(=O)N
Properties
Properties
 
BP:
430.2°C at 760 mmHg  
Form:
Solid  
MP:
207 °C  
Refractive Index:
8 ° (C=5, H2O)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
170  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
-3.6  

Downstream Synthesis Route

[1]ACSChemicalNeuroscience,2017,vol.8,p.1724-1734

[2]NipponNogeikagakuKaishi,1949,vol.23,p.269    Chem.Abstr.,1951,p.3528

[1]AminoAcids,2010,vol.39,p.1177-1182

[2]Chemicalandpharmaceuticalbulletin,1971,vol.19,p.1301-1307

[1]Bioscience,BiotechnologyandBiochemistry,2008,vol.72,p.1206-1211

[2]Bioscience,BiotechnologyandBiochemistry,1992,vol.56,p.708-711

[3]Bioscience,BiotechnologyandBiochemistry,1992,vol.56,p.708-711

[4]Bioscience,BiotechnologyandBiochemistry,2009,vol.73,p.2677-2683

[1]ProcessBiochemistry,2014,vol.49,p.1429-1439

[2]Bioscience,BiotechnologyandBiochemistry,1998,vol.62,p.1279-1283

[3]Bioscience,BiotechnologyandBiochemistry,1993,vol.57,p.481-483

[4]Bioscience,BiotechnologyandBiochemistry,2010,vol.74,p.1936-1939

[5]RSCAdvances,2014,vol.4,p.9021-9030

[1]Bioscience,BiotechnologyandBiochemistry,1992,vol.56,p.689

Literature

Title: Topical delivery of l-theanine ameliorates TPA-induced acute skin inflammation via downregulating endothelial PECAM-1 and neutrophil infiltration and activation.

Journal: Chemico-biological interactions 20180325

Title: Theanine prevents doxorubicin-induced acute hepatotoxicity by reducing intrinsic apoptotic response.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150401

Title: Rapid and selective quantification of L-theanine in ready-to-drink teas from Chinese market using SPE and UPLC-UV.

Journal: Food chemistry 20121115

Title: L-Theanine extends lifespan of adult Caenorhabditis elegans.

Journal: European journal of nutrition 20120901

Title: Application of novel electrospun nanofibrous membranes with different modifications for immobilising glutamine synthetase.

Journal: Journal of the science of food and agriculture 20120830

Title: Enhancement of postoperative recovery by preoperative oral co-administration of the amino acids, cystine and theanine, in a mouse surgical model.

Journal: Clinical nutrition (Edinburgh, Scotland) 20120801

Title: An enzyme-encapsulated microreactor for efficient theanine synthesis.

Journal: Chemical communications (Cambridge, England) 20120718

Title: Effect of salt treatment on theanine biosynthesis in Camellia sinensis seedlings.

Journal: Plant physiology and biochemistry : PPB 20120701

Title: Cancer stem cells: potential target for bioactive food components.

Journal: The Journal of nutritional biochemistry 20120701

Title: [Effects of theanine on monoamine neurotransmitters and related genes in cerebral ischemia-reperfusion injury rats].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20120701

Title: Flavor characteristics of seven grades of black tea produced in Turkey.

Journal: Journal of agricultural and food chemistry 20120627

Title: Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.

Journal: Neuropharmacology 20120601

Title: Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.

Journal: Biochemical and biophysical research communications 20120601

Title: Theanine is a candidate amino acid for pharmacological stabilization of mast cells.

Journal: Amino acids 20120501

Title: Magnesium nutrition on accumulation and transport of amino acids in tea plants.

Journal: Journal of the science of food and agriculture 20120501

Title: Modulation of irinotecan-induced genomic DNA damage by theanine.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Reactions of green and black teas with Cu(II).

Journal: Food & function 20120401

Title: L-theanine partially counteracts caffeine-induced sleep disturbances in rats.

Journal: Pharmacology, biochemistry, and behavior 20120401

Title: Green tea and theanine: health benefits.

Journal: International journal of food sciences and nutrition 20120301

Title: Amino acid and vitamin supplementation improved health conditions in elderly participants.

Journal: Journal of clinical biochemistry and nutrition 20120301

Title: Behavioral and molecular evidence for psychotropic effects in L-theanine.

Journal: Psychopharmacology 20120201

Title: l-Theanine prevents alcoholic liver injury through enhancing the antioxidant capability of hepatocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120201

Title: Determination of theanine and gamma-aminobutyric acid in tea by high performance- liquid chromatography with precolumn derivatization.

Journal: Se pu = Chinese journal of chromatography 20120201

Title: Unique induction of CA1 LTP components after intake of theanine, an amino acid in tea leaves and its effect on stress response.

Journal: Cellular and molecular neurobiology 20120101

Title: Development and certification of green tea-containing standard reference materials.

Journal: Analytical and bioanalytical chemistry 20120101

Title: Natural antioxidants in prevention and management of Alzheimer's disease.

Journal: Frontiers in bioscience (Elite edition) 20120101

Title: Tea and cognitive health in late life: current evidence and future directions.

Journal: The journal of nutrition, health & aging 20120101

Title: A meta-analysis of tea drinking and risk of Parkinson's disease.

Journal: TheScientificWorldJournal 20120101

Title: The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial.

Journal: Alternative medicine review : a journal of clinical therapeutic 20111201

Title: The anti-obesity effect of Lethariella cladonioides in 3T3-L1 cells and obese mice.

Journal: Nutrition research and practice 20111201

Title: Antidepressant-like effects of L-theanine in the forced swim and tail suspension tests in mice.

Journal: Phytotherapy research : PTR 20111101

Title: [Raman spectral analysis of theanine].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20111101

Title: [Effects of theanine on cerebral ischemia-reperfusion injury in rats].

Journal: Wei sheng yan jiu = Journal of hygiene research 20111101

Title: Metabolic dependence of green tea on plucking positions revisited: a metabolomic study.

Journal: Journal of agricultural and food chemistry 20111012

Title: Facilitated neurogenesis in the developing hippocampus after intake of theanine, an amino acid in tea leaves, and object recognition memory.

Journal: Cellular and molecular neurobiology 20111001

Title: Inhibition of the replication of hepatitis B virus in vitro by pu-erh tea extracts.

Journal: Journal of agricultural and food chemistry 20110928

Title: A randomized targeted amino acid therapy with behaviourally at-risk adopted children.

Journal: Child: care, health and development 20110901

Title: Optimum conditions for the water extraction of L-theanine from green tea.

Journal: Journal of separation science 20110901

Title: L-Theanine: properties, synthesis and isolation from tea.

Journal: Journal of the science of food and agriculture 20110830

Title: Theanine intake improves the shortened lifespan, cognitive dysfunction and behavioural depression that are induced by chronic psychosocial stress in mice.

Journal: Free radical research 20110801

Title: Neuroprotective effects of theanine and its preventive effects on cognitive dysfunction.

Journal: Pharmacological research 20110801

Title: Characterization of tea cultivated at four different altitudes using 1H NMR analysis coupled with multivariate statistics.

Journal: Journal of agricultural and food chemistry 20110525

Title: Production of bioactive γ-glutamyl transpeptidase in Escherichia coli using SUMO fusion partner and application of the recombinant enzyme to L-theanine synthesis.

Journal: Current microbiology 20110501

Title: Anti-invasive activity of α-tocopherol against hepatoma cells in culture via protein kinase C inhibition.

Journal: Journal of clinical biochemistry and nutrition 20110501

Title: Black tea improves attention and self-reported alertness.

Journal: Appetite 20110401

Title: A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study.

Journal: Journal of medicinal food 20110401

Title: L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.

Journal: The Journal of clinical psychiatry 20110101

Title: Construction, characterization, and preliminary BAC-end sequence analysis of a bacterial artificial chromosome library of the tea plant (Camellia sinensis).

Journal: Journal of biomedicine & biotechnology 20110101

Title: Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial.

Journal: BMC complementary and alternative medicine 20110101

Title: Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds.

Journal: BMC genomics 20110101

Title: The effects of a high dosage of creatine and caffeine supplementation on the lean body mass composition of rats submitted to vertical jumping training.

Journal: Journal of the International Society of Sports Nutrition 20110101

Title: The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols.

Journal: BMC biochemistry 20110101

Title: 2-Aza-niumyl-4-(ethyl-carbamo-yl)butano-ate: the zwitterionic form of the amino acid theanine.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Serum levels of brain-derived neurotrophic factor and cortisol to sulfate of dehydroepiandrosterone molar ratio associated with clinical response to L-theanine as augmentation of antipsychotic therapy in schizophrenia and schizoaffective disorder patients.

Journal: Clinical neuropharmacology 20110101

Title: Protective Action of Neurotrophic Factors and Estrogen against Oxidative Stress-Mediated Neurodegeneration.

Journal: Journal of toxicology 20110101

Title: Proteomic analysis of young leaves at three developmental stages in an albino tea cultivar.

Journal: Proteome science 20110101

Title: Early effect of NEURAPAS® balance on current source density (CSD) of human EEG.

Journal: BMC psychiatry 20110101

Title: Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars.

Journal: PloS one 20110101

Title: Nerve and behavioral responses of mice to various umami substances.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Stuck at the bench: Potential natural neuroprotective compounds for concussion.

Journal: Surgical neurology international 20110101

Title: Increased glutathione synthesis following Nrf2 activation by vanadyl sulfate in human chang liver cells.

Journal: International journal of molecular sciences 20110101

Title: Modeling natural anti-inflammatory compounds by molecular topology.

Journal: International journal of molecular sciences 20110101

Title: Natural products and body weight control.

Journal: North American journal of medical sciences 20110101

Title: A hand-held electronic tongue based on fluorometry for taste assessment of tea.

Journal: Biosensors & bioelectronics 20101215

Title: Development of efficient enzymatic production of theanine by γ-glutamyltranspeptidase from a newly isolated strain of Bacillus subtilis, SK11.004.

Journal: Journal of the science of food and agriculture 20101201

Title: The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness.

Journal: Nutritional neuroscience 20101201

Title: Completing an ironman triathlon with pneumonia: a case report.

Journal: Asian journal of sports medicine 20101201

Title: Enzymatic synthesis of theanine from glutamic acid γ-methyl ester and ethylamine by immobilized Escherichia coli cells with γ-glutamyltranspeptidase activity.

Journal: Amino acids 20101101

Title: Geographical and climatic dependencies of green tea (Camellia sinensis) metabolites: a (1)H NMR-based metabolomics study.

Journal: Journal of agricultural and food chemistry 20101013

Title: Effects of Ocimum sanctum and Camellia sinensis on stress-induced anxiety and depression in male albino Rattus norvegicus.

Journal: Indian journal of pharmacology 20101001

Title: Tea, flavonoids and stroke in man and mouse.

Journal: Archives of biochemistry and biophysics 20100901

Title: Impact of nitrogen supply on carbon/nitrogen allocation: a case study on amino acids and catechins in green tea [Camellia sinensis (L.) O. Kuntze] plants.

Journal: Plant biology (Stuttgart, Germany) 20100901

Title: Synthesis of theanine from glutamic acid gamma-methyl ester and ethylamine catalyzed by Escherichia coli having gamma-glutamyltranspeptidase activity.

Journal: Biotechnology letters 20100801

Title: L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway.

Journal: Neuroscience 20100714

Title: An LC-ESI/MS method for determining theanine in green tea dietary supplements.

Journal: Analytical and bioanalytical chemistry 20100701

Title: The cessation and detoxification effect of tea filters on cigarette smoke.

Journal: Science China. Life sciences 20100501

Title: A revolutionary approach for the cessation of smoking.

Journal: Science China. Life sciences 20100501

Title: L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.

Journal: Appetite 20100401

Title: Overlap of Erosive and Non-erosive Reflux Diseases With Functional Gastrointestinal Disorders According to Rome III Criteria.

Journal: Journal of neurogastroenterology and motility 20100401

Title: Cystine and theanine supplementation restores high-intensity resistance exercise-induced attenuation of natural killer cell activity in well-trained men.

Journal: Journal of strength and conditioning research 20100301

Title: Combined administration of (L)-cystine and (L)-theanine enhances immune functions and protects against influenza virus infection in aged mice.

Journal: The Journal of veterinary medical science 20100201

Title: Distribution and biosynthesis of theanine in Theaceae plants.

Journal: Plant physiology and biochemistry : PPB 20100101

Title: Chemistry of secondary polyphenols produced during processing of tea and selected foods.

Journal: International journal of molecular sciences 20100101

Title: [Theanine, EGCG and caffeine determinated by HPLC].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100101

Title: Beneficial effects of green tea: a literature review.

Journal: Chinese medicine 20100101

Title: Sub-critical water extraction of residual green tea to produce a roasted green tea-like extract.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: Suppression of exercise-induced neutrophilia and lymphopenia in athletes by cystine/theanine intake: a randomized, double-blind, placebo-controlled trial.

Journal: Journal of the International Society of Sports Nutrition 20100101

Title: Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.

Journal: Nutrition journal 20100101

Title: Effects of (L)-cystine and (L)-theanine supplementation on the common cold: a randomized, double-blind, and placebo-controlled trial.

Journal: Journal of amino acids 20100101

Title: Neuroprotection by radical avoidance: search for suitable agents.

Journal: Molecules (Basel, Switzerland) 20091207

Title: l-Theanine, an amino acid in green tea, attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity: reduction in oxidative damage and inactivation of ERK/p38 kinase and NF-kappaB pathways.

Journal: Free radical biology & medicine 20091201

Title: A novel catalytic ability of gamma-glutamylcysteine synthetase of Escherichia coli and its application in theanine production.

Journal: Bioscience, biotechnology, and biochemistry 20091201

Title: Repeated batch production of theanine by coupled fermentation with energy transfer using membrane-enclosed gamma-glutamylmethylamide synthetase and dried yeast cells.

Journal: Bioscience, biotechnology, and biochemistry 20091201

Title: Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat.

Journal: AANA journal 20091201

Title: [Theanine affects sedative effect of pentobarbital sodium in ICR mice].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20091101

Title: The effect of taurine, a novel biochemical modulator, on the antitumor activity of doxorubicin.

Journal: Biological & pharmaceutical bulletin 20090901

Title: Bioactive components of tea: cancer, inflammation and behavior.

Journal: Brain, behavior, and immunity 20090801

Title: Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20090801

Title: Impact of two types of Internet-based information on medical students' performance in an Objective Structured Clinical Exam (OSCE).

Journal: Patient education and counseling 20090701

Title: The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task.

Journal: Brain topography 20090601

Title: Changes in the composition of raw tea leaves from the Korean Yabukida plant during high-temperature processing to pan-fried Kamairi-cha green tea.

Journal: Journal of food science 20090601

Title: Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial.

Journal: Bioscience, biotechnology, and biochemistry 20090423

Title: Rat electropharmacograms of the flavonoids rutin and quercetin in comparison to those of moclobemide and clinically used reference drugs suggest antidepressive and/or neuroprotective action.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401

Title: Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells.

Journal: Cytotechnology 20090401

Title: Theanine, gamma-glutamylethylamide, a unique amino acid in tea leaves, modulates neurotransmitter concentrations in the brain striatum interstitium in conscious rats.

Journal: Amino acids 20090101

Title: Tea and health: preventive and therapeutic usefulness in the elderly?

Journal: Current opinion in clinical nutrition and metabolic care 20090101

Title: Ethylamine content and theanine biosynthesis in different organs of Camellia sinensis seedlings.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: Co-administration of l-cystine and l-theanine enhances efficacy of influenza vaccination in elderly persons: nutritional status-dependent immunogenicity.

Journal: Geriatrics & gerontology international 20081201

Title: L-theanine elicits an umami taste with inosine 5'-monophosphate.

Journal: Bioscience, biotechnology, and biochemistry 20081101

Title: Determination of theanine, GABA, and other amino acids in green, oolong, black, and Pu-erh teas with dabsylation and high-performance liquid chromatography.

Journal: Journal of agricultural and food chemistry 20080910

Title: [Determination of hydroxyproline in collagenous proteins by high performance liquid chromatography-mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20080901

Title: Immobilization of Escherichia coli novablue gamma-glutamyltranspeptidase in Ca-alginate-kappa-carrageenan beads.

Journal: Applied biochemistry and biotechnology 20080801

Title: The combined effects of L-theanine and caffeine on cognitive performance and mood.

Journal: Nutritional neuroscience 20080801

Title: [The effect of theanine on oxygen-induced retinal neovascularization in the neonatal rat].

Journal: Nippon Ganka Gakkai zasshi 20080801

Title: Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death.

Journal: Neurotoxicology 20080701

Title: Theanine, an ingredient of green tea, inhibits [3H]glutamine transport in neurons and astroglia in rat brain.

Journal: Journal of neuroscience research 20080601

Title: Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells.

Journal: Phytotherapy research : PTR 20080501

Title: Altered levels of oxidation and phospholipase C isozyme expression in the brains of theanine-administered rats.

Journal: Biological & pharmaceutical bulletin 20080501

Title: Effects of theanine, a unique amino acid in tea leaves, on memory in a rat behavioral test.

Journal: Bioscience, biotechnology, and biochemistry 20080501

Title: Administration of theanine, a unique amino acid in tea leaves, changed feeding-relating components in serum and feeding behavior in rats.

Journal: Bioscience, biotechnology, and biochemistry 20080501

Title: Theanine production by coupled fermentation with energy transfer using gamma-glutamylmethylamide synthetase of Methylovorus mays No. 9.

Journal: Bioscience, biotechnology, and biochemistry 20080501

Title: The effects of L-theanine, caffeine and their combination on cognition and mood.

Journal: Biological psychology 20080201

Title: Psychological effects of dietary components of tea: caffeine and L-theanine.

Journal: Nutrition reviews 20080201

Title: L-theanine intervention enhances human gammadeltaT lymphocyte function.

Journal: Nutrition reviews 20080201

Title: Theanine prevents memory impairment induced by repeated cerebral ischemia in rats.

Journal: Phytotherapy research : PTR 20080101

Title: Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.

Journal: Psychopharmacology 20080101

Title: Cloning and expression of Methylovorus mays No. 9 gene encoding gamma-glutamylmethylamide synthetase: an enzyme usable in theanine formation by coupling with the alcoholic fermentation system of baker's yeast.

Journal: Bioscience, biotechnology, and biochemistry 20080101

Title: L-theanine, a natural constituent in tea, and its effect on mental state.

Journal: Asia Pacific journal of clinical nutrition 20080101

Title: Aqueous fish extract increases survival in the mouse model of cytostatic toxicity.

Journal: Journal of experimental & clinical cancer research : CR 20080101

Title: Enhancement of antigen-specific immunoglobulin G production in mice by co-administration of L-cystine and L-theanine.

Journal: The Journal of veterinary medical science 20071201

Title: A soothing sip of focus. The latest on tea: it might quiet distracted minds.

Journal: U.S. news & world report 20071008

Title: Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: II. Characterization in the freely moving rat by means of quantitative field potential analysis.

Journal: The Journal of pharmacy and pharmacology 20071001

Title: Involvement of GABA(A) receptors in the neuroprotective effect of theanine on focal cerebral ischemia in mice.

Journal: Journal of pharmacological sciences 20071001

Title: [Effects of theanine and houpu extract in 7-day chick social separation-stress procedure].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001

Title: Theanine, r-glutamylethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation.

Journal: Life sciences 20070929

Title: Determination of amino acids in tea leaves and beverages using capillary electrophoresis with light-emitting diode-induced fluorescence detection.

Journal: Talanta 20070915

Title: [Separation and quantification of theanine enantiomers using high performance liquid chromatography coupled with chiral derivatization].

Journal: Se pu = Chinese journal of chromatography 20070901

Title: Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: I. electrophysiological characterization in the rat hippocampus in-vitro.

Journal: The Journal of pharmacy and pharmacology 20070801

Title: Differentiation of green, white, black, Oolong, and Pu-erh teas according to their free amino acids content.

Journal: Journal of agricultural and food chemistry 20070725

Title: Effects of green tea fractions on oxygen-induced retinal neovascularization in the neonatal rat.

Journal: Journal of clinical biochemistry and nutrition 20070701

Title: [Determination of amino acids in tea samples by capillary electrophoresis with partition cell and indirect ultraviolet detection].

Journal: Se pu = Chinese journal of chromatography 20070301

Title: Effect of valerian extract preparation (BIM) on the sleep-wake cycle in rats.

Journal: Biological & pharmaceutical bulletin 20070201

Title: Characterization of theanine-forming enzyme from Methylovorus mays no. 9 in respect to utilization of theanine production.

Journal: Bioscience, biotechnology, and biochemistry 20070201

Title: Spontaneous renal tubular hyperplastic and neoplastic lesions in three Sprague-Dawley rats from a 90-day toxicity study.

Journal: Toxicologic pathology 20070201

Title: Structure-activity relationships of tea compounds against human cancer cells.

Journal: Journal of agricultural and food chemistry 20070124

Title: L-Theanine reduces psychological and physiological stress responses.

Journal: Biological psychology 20070101

Title: Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats.

Journal: Journal of inflammation (London, England) 20070101

Title: The deployment of intersensory selective attention: a high-density electrical mapping study of the effects of theanine.

Journal: Clinical neuropharmacology 20070101

Title: Source density analysis of the human EEG after ingestion of a drink containing decaffeinated extract of green tea enriched with L-theanine and theogallin.

Journal: Nutritional neuroscience 20070101

Title: Multivariate analysis for 1H-NMR spectra of two hundred kinds of tea in the world.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20061001

Title: Determination of theanine in commercial tea by liquid chromatography with fluorescence and diode array ultraviolet detection.

Journal: Journal of agricultural and food chemistry 20060920

Title: Expression optimization and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Escherichia coli novablue.

Journal: The protein journal 20060901

Title: A 13-week dietary toxicity and toxicokinetic study with l-theanine in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701

Title: Molecular and sensory studies on the umami taste of Japanese green tea.

Journal: Journal of agricultural and food chemistry 20060405

Title: Induction of neutral endopeptidase (NEP) activity of SK-N-SH cells by natural compounds from green tea.

Journal: The Journal of pharmacy and pharmacology 20060401

Title: Efficacy of theanine is connected with theanine metabolism by any enzyme, not only drug metabolizing enzymes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060201

Title: Cloning and expression of Pseudomonas taetrolens Y-30 gene encoding glutamine synthetase: an enzyme available for theanine production by coupled fermentation with energy transfer.

Journal: Bioscience, biotechnology, and biochemistry 20060201

Title: Pharmacology and therapeutic uses of theanine.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060101

Title: Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice.

Journal: BMC complementary and alternative medicine 20060101

Title: The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression.

Journal: Cancer cell international 20060101

Title: Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.

Journal: BioFactors (Oxford, England) 20060101

Title: The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent.

Journal: Journal of herbal pharmacotherapy 20060101

Title: Effects of theanine on alcohol metabolism and hepatic toxicity.

Journal: Biological & pharmaceutical bulletin 20050901

Title: Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission.

Journal: Nutritional neuroscience 20050801

Title: L-theanine . Monograph.

Journal: Alternative medicine review : a journal of clinical therapeutic 20050601

Title: Medicinal benefits of green tea: Part I. Review of noncancer health benefits.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20050601

Title: A novel assay method for theanine synthetase activity by capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050505

Title: Theanine production by coupled fermentation with energy transfer employing Pseudomonas taetrolens Y-30 glutamine synthetase and baker's yeast cells.

Journal: Bioscience, biotechnology, and biochemistry 20050401

Title: Pharmacokinetics of theanine enantiomers in rats.

Journal: Chirality 20050301

Title: Toxicity of green tea extracts and their constituents in rat hepatocytes in primary culture.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050201

Title: Inhibitory activity of a green tea extract and some of its constituents on multidrug resistance-associated protein 2 functionality.

Journal: Planta medica 20050201

Title: Pu-erh tea supplementation suppresses fatty acid synthase expression in the rat liver through downregulating Akt and JNK signalings as demonstrated in human hepatoma HepG2 cells.

Journal: Oncology research 20050101

Title: The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans.

Journal: Human psychopharmacology 20041001

Title: Purification and characterization of glutamine synthetase of Pseudomonas taetrolens Y-30: an enzyme usable for production of theanine by coupling with the alcoholic fermentation system of baker's yeast.

Journal: Bioscience, biotechnology, and biochemistry 20040901

Title: Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level.

Journal: Cancer letters 20040830

Title: Possible involvement of group I mGluRs in neuroprotective effect of theanine.

Journal: Biochemical and biophysical research communications 20040716

Title: Neuroprotective effect of gamma-glutamylethylamide (theanine) on cerebral infarction in mice.

Journal: Neuroscience letters 20040603

Title: Metabolite profiling using (1)H NMR spectroscopy for quality assessment of green tea, Camellia sinensis (L.).

Journal: Journal of agricultural and food chemistry 20040225

Title: Simultaneous analysis of theanine, chlorogenic acid, purine alkaloids and catechins in tea samples with the help of multi-dimension information of on-line high performance liquid chromatography/electrospray-mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20040218

Title: Analysis of derivatized and underivatized theanine enantiomers by high-performance liquid chromatography/atmospheric pressure ionization-mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice.

Journal: In vivo (Athens, Greece) 20040101

Title: Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents.

Journal: Biochimica et biophysica acta 20031205

Title: Capillary electrophoretic determination of theanine, caffeine, and catechins in fresh tea leaves and oolong tea and their effects on rat neurosphere adhesion and migration.

Journal: Journal of agricultural and food chemistry 20031203

Title: Rapid analysis of amino acids in Japanese green tea by microchip electrophoresis using plastic microchip and fluorescence detection.

Journal: Journal of chromatography. A 20030926

Title: Theanine, gamma-glutamylethylamide, is metabolized by renal phosphate-independent glutaminase.

Journal: Biochimica et biophysica acta 20030317

Title: Direct determination of free amino acids and sugars in green tea by anion-exchange chromatography with integrated pulsed amperometric detection.

Journal: Journal of chromatography. A 20021227

Title: Neuroprotective effects of the green tea components theanine and catechins.

Journal: Biological & pharmaceutical bulletin 20021201

Title: Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors.

Journal: Bioscience, biotechnology, and biochemistry 20021201

Title: [Glutamate transporter mediated increase of antitumor activity by theanine, an amino acid in green tea].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101

Title: [Determination of theanine in tea leaves by HPLC-inhibited chemiluminescence with Co2+ catalyst].

Journal: Se pu = Chinese journal of chromatography 20021101

Title: Effect of dihydrokainate on the antitumor activity of doxorubicin.

Journal: Cancer letters 20020528

Title: Effects of dietary powdered green tea and theanine on tumor growth and endogenous hyperlipidemia in hepatoma-bearing rats.

Journal: Bioscience, biotechnology, and biochemistry 20020401

Title: Enhancement of the activity of doxorubicin by inhibition of glutamate transporter.

Journal: Toxicology letters 20010915

Title: Inhibitory effects of theanine and sera from theanine-fed rats on receptor-mediated cancer cell invasion beneath mesothelial-cell monolayers.

Journal: Cytotechnology 20010701

Title: Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin.

Journal: Toxicology letters 20010430

Title: Vuong QV, et al. L-Theanine: properties, synthesis and isolation from tea. J Sci Food Agric. 2011 Aug 30;91(11):1931-9.

Title: Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74(1):39-45.

Title: Takeshima M, et al. l-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes. J Clin Biochem Nutr. 2016 Sep;59(2):93-99.

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Tags:3081-61-6 Molecular Formula|3081-61-6 MDL|3081-61-6 SMILES|3081-61-6 L-Theanine