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3092-17-9,MFCD00079455
Catalog No.:AA01FL14

3092-17-9 | Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-,monohydrochloride, (±)-

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01FL14
Chemical Name:
Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-,monohydrochloride, (±)-
CAS Number:
3092-17-9
Molecular Formula:
C12H19ClN2O4
Molecular Weight:
290.7433
MDL Number:
MFCD00079455
SMILES:
COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
NSC Number:
758429
Properties
Computed Properties
 
Complexity:
263  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Literature

Title: [Orthostatic hypotension: implications for the treatment of cardiovascular diseases].

Journal: Presse medicale (Paris, France : 1983) 20121101

Title: The combination of octreotide and midodrine is not superior to albumin in preventing recurrence of ascites after large-volume paracentesis.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20121001

Title: MicroRNA changes in rat mesentery and serum associated with drug-induced vascular injury.

Journal: Toxicology and applied pharmacology 20120801

Title: A prospective, 1-year follow-up study of postural tachycardia syndrome.

Journal: Mayo Clinic proceedings 20120801

Title: Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome.

Journal: Journal of the American College of Cardiology 20120724

Title: Peptides in postural orthostatic tachycardia syndrome: players or epiphenomena?

Journal: Journal of the American College of Cardiology 20120724

Title: The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20120401

Title: Trials to address efficacy of midodrine 18 years after it gains FDA approval.

Journal: JAMA 20120321

Title: Probable hereditary multiple system atrophy-autonomic (MSA-A) in a family in the United States.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120301

Title: Midodrine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study.

Journal: Journal of hepatology 20120201

Title: Hepatorenal syndrome: are we missing some prognostic factors?

Journal: Digestive diseases and sciences 20120101

Title: Takotsubo cardiomyopathy after midodrine therapy.

Journal: Texas Heart Institute journal 20120101

Title: Refractory hypotension due to Rogaine® (minoxidil) ingestion managed with midodrine.

Journal: Clinical toxicology (Philadelphia, Pa.) 20111201

Title: Ejaculatory dysfunction in spinal cord injury men is suggestive of dyssynergic ejaculation.

Journal: European journal of physical and rehabilitation medicine 20111201

Title: Effectiveness of midodrine treatment in patients with recurrent vasovagal syncope not responding to non-pharmacological treatment (STAND-trial).

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111101

Title: Orthostatic effects of midodrine versus L-NAME on cerebral blood flow and the renin-angiotensin-aldosterone system in tetraplegia.

Journal: Archives of physical medicine and rehabilitation 20111101

Title: New insights into the management of hepato-renal syndrome.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20110901

Title: A patient treated with tilt training and midodrine after 68 seconds asystole during head-up tilt table testing.

Journal: Acta cardiologica 20110801

Title: [Therapies for postural tachycardia syndrome in children].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20110601

Title: Liver transplant outcomes for patients with hepatorenal syndrome treated with pretransplant vasoconstrictors and albumin.

Journal: Transplantation 20110527

Title: FDA takes slow road toward withdrawal of drug approved with fast-track process.

Journal: JAMA 20110309

Title: Withdrawing FDA approval of midodrine after marketing.

Journal: JAMA 20110223

Title: Midodrine and furosemide-induced natriuresis in cirrhotics with ascites.

Journal: Alimentary pharmacology & therapeutics 20110201

Title: [Postural orthostatic tachycardia syndrome: current concepts in pathophysiology, diagnosis and therapeutic options].

Journal: Fortschritte der Neurologie-Psychiatrie 20110201

Title: Effects of promethazine and midodrine on orthostatic tolerance.

Journal: Aviation, space, and environmental medicine 20110101

Title: Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Response to research letter titled 'Severe transient hypertension after greater palatine foramen block in a patient taking midodrine'.

Journal: American journal of otolaryngology 20110101

Title: Are there any contraindications to using midodrine for intradialytic hypotension?

Journal: Seminars in dialysis 20110101

Title: Evaluation and management of syncope.

Journal: Minerva cardioangiologica 20101201

Title: Accelerated approval and possible withdrawal of midodrine.

Journal: JAMA 20101117

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Oversight of fast-track drug approval by FDA stuck in low gear, critics say.

Journal: JAMA 20101027

Title: Isolated sympathetic failure with autoimmune autonomic ganglionopathy.

Journal: Pediatric neurology 20101001

Title: Regulatory actions on the off-label use of prescription drugs: ongoing controversy and contradiction in 2009 and 2010.

Journal: Journal of managed care pharmacy : JMCP 20101001

Title: Midodrine hydrochloride is safe and effective in older people with neurocardiogenic syncope.

Journal: Journal of the American Geriatrics Society 20101001

Title: The effects of midodrine on the natriuretic response to furosemide in cirrhotics with ascites.

Journal: Alimentary pharmacology & therapeutics 20101001

Title: Effects of midodrine hydrochloride on blood pressure and cerebral blood flow during orthostasis in persons with chronic tetraplegia.

Journal: Archives of physical medicine and rehabilitation 20100901

Title: Clinostatic hypertension and orthostatic hypotension.

Journal: Clinical cardiology 20100601

Title: Stereoselective determination of midodrine and desglymidodrine in culture medium: application to a biotransformation study employing endophytic fungi.

Journal: Electrophoresis 20100501

Title: Severe transient hypertension after greater palatine foramen block in a patient taking midodrine.

Journal: American journal of otolaryngology 20100101

Title: The midodrine withdrawal.

Journal: American journal of therapeutics 20100101

Title: Hemodialysis in hypotensive heart failure using midodrine.

Journal: The American journal of the medical sciences 20091201

Title: Modulations of autonomic cardiovascular control following acute alpha-adrenergic treatment in chronic hypotension.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091101

Title: Chronic hypotension and modulation of autonomic cardiovascular regulation.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20091101

Title: Pharmacological options in the management of orthostatic hypotension in older adults.

Journal: Expert review of cardiovascular therapy 20091101

Title: Oral midodrine for prostaglandin e1 induced priapism in spinal cord injured patients.

Journal: The Journal of urology 20090901

Title: Combination treatment with octreotide, midodrine, and albumin improves survival in patients with type 1 and type 2 hepatorenal syndrome.

Journal: Journal of clinical gastroenterology 20090801

Title: The value of sequential dialysis, mannitol and midodrine in managing children prone to dialysis failure.

Journal: Pediatric nephrology (Berlin, Germany) 20090801

Title: Oral-based controlled release formulations using poly(acrylic acid) microgels.

Journal: Drug development and industrial pharmacy 20090801

Title: [Efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope].

Journal: Zhonghua yi xue za zhi 20090728

Title: Calcific embolus causing subarachnoid hemorrhage.

Journal: Neurology 20090721

Title: alpha-Adrenoceptor agonists for the treatment of vasovagal syncope: a meta-analysis of worldwide published data.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20090701

Title: Differences in skin sympathetic involvements between two chronic autonomic disorders: multiple system atrophy and pure autonomic failure.

Journal: Parkinsonism & related disorders 20090601

Title: The management of hepatorenal syndrome.

Journal: Minerva gastroenterologica e dietologica 20090601

Title: A systematic review of the management of orthostatic hypotension after spinal cord injury.

Journal: Archives of physical medicine and rehabilitation 20090501

Title: Midodrine in the prevention of hepatorenal syndrome type 2 recurrence: a case-control study.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090401

Title: Lower ambulatory blood pressure in chronic fatigue syndrome.

Journal: Psychosomatic medicine 20090401

Title: Midodrine and octreotide in treatment of cirrhosis-related hemodynamic complications.

Journal: The Annals of pharmacotherapy 20090401

Title: Autoimmune autonomic ganglionopathy with late-onset encephalopathy.

Journal: Autonomic neuroscience : basic & clinical 20090312

Title: Hemodynamic determinants of chronic hypotension and their modification through vasopressor application.

Journal: The journal of physiological sciences : JPS 20090301

Title: The effect of 1 month of therapy with midodrine, octreotide-LAR and albumin in refractory ascites: a pilot study.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20090201

Title: Outcomes in adolescents with postural orthostatic tachycardia syndrome treated with midodrine and beta-blockers.

Journal: Pacing and clinical electrophysiology : PACE 20090201

Title: Orthostatic hypotension associated with dorsal medullary cavernous angioma.

Journal: Acta neurologica Scandinavica 20090101

Title: Midodrine for the treatment of organic anejaculation but not spinal cord injury: a prospective randomized placebo-controlled double-blind clinical study.

Journal: International journal of impotence research 20090101

Title: The use of midodrine in patients with advanced heart failure.

Journal: Congestive heart failure (Greenwich, Conn.) 20090101

Title: Midodrine improves orgasm in spinal cord-injured men: the effects of autonomic stimulation.

Journal: The journal of sexual medicine 20081201

Title: Evidence-based treatment for vasovagal syncope.

Journal: Heart rhythm 20081101

Title: Efficacy and safety of terlipressin in cirrhotic patients with variceal bleeding or hepatorenal syndrome.

Journal: Advances in therapy 20081101

Title: Perceived physiological and orgasmic sensations at ejaculation in spinal cord injured men.

Journal: The journal of sexual medicine 20081001

Title: Current concepts in the evaluation and management of syncope.

Journal: Current cardiology reports 20080901

Title: Pharmacokinetic and pharmacodynamic effects of midodrine on blood pressure, the autonomic nervous system, and plasma natriuretic peptides: a prospective, randomized, single-blind, two-period, crossover, placebo-controlled study.

Journal: Clinical therapeutics 20080901

Title: [Effect of selective alpha1 receptor agonist in the treatment of children with postural orthostatic tachycardia syndrome].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20080901

Title: Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20080801

Title: Vasoconstrictor therapy for patients with cirrhosis with ascites but without hepatorenal syndrome.

Journal: Hepatology (Baltimore, Md.) 20080801

Title: Oral midodrine is effective for the treatment of hypotension associated with carotid artery stenting.

Journal: Journal of cardiovascular pharmacology and therapeutics 20080601

Title: Midodrine versus albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotics: a randomized pilot study.

Journal: The American journal of gastroenterology 20080601

Title: Acute dystonia induced by the combination of midodrine and perphenazine.

Journal: Journal of neurology 20080501

Title: Blood pressure changes during sexual stimulation, ejaculation and midodrine treatment in men with spinal cord injury.

Journal: BJU international 20080201

Title: Midodrine-induced vascular ischemia in a hemodialysis patient: a case report and literature review.

Journal: Renal failure 20080101

Title: Metabolic and functional profiling of the ischemic/reperfused rat retina.

Journal: The Journal of comparative neurology 20071101

Title: Midodrine improves ejaculation in spinal cord injured men.

Journal: The Journal of urology 20071101

Title: Comment on 'Midodrine hydrochloride and L-threo-3,4-dihydroxy-phenylserine preserve cerebral blood flow in hemodialysis patients with orthostatic hypotension' by Fujisaki et al.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20071001

Title: Orthostatic hypotension in the elderly: diagnosis and treatment.

Journal: The American journal of medicine 20071001

Title: Autonomic failure: observations of a physician-patient.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20070801

Title: Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: a possible association with oral midodrine treatment.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070515

Title: Treatment of hepatic hydrothorax with vasoconstrictor drugs.

Journal: Scandinavian journal of gastroenterology 20070401

Title: Octreotide/Midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome.

Journal: Digestive diseases and sciences 20070301

Title: Midodrine treatment in the management of severe orthostatic hypotension after hemangioblastoma surgery.

Journal: Acta neurochirurgica 20070301

Title: Orthostatic hypotension: evaluation and treatment.

Journal: Cardiovascular & hematological disorders drug targets 20070301

Title: Effects of a 7-day treatment with midodrine in non-azotemic cirrhotic patients with and without ascites.

Journal: Journal of hepatology 20070201

Title: In vivo pharmacodynamic interactions between two drugs used in orthostatic hypotension--midodrine and dihydroergotamine.

Journal: Fundamental & clinical pharmacology 20070201

Title: Midodrine hydrochloride and L-threo-3,4-dihydroxy-phenylserine preserve cerebral blood flow in hemodialysis patients with orthostatic hypotension.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20070201

Title: A case of neurally mediated syncope induced by laughter successfully treated with combination of propranolol and midodrine.

Journal: International heart journal 20070101

Title: Prolonged supine hypertension due to midodrine use in an orthostatic hypotensive child.

Journal: Pediatric cardiology 20070101

Title: Midodrine: insidious development of urologic adverse effects in patients with spinal cord injury: a report of 2 cases.

Journal: Advances in therapy 20070101

Title: Treatment of postural tachycardia syndrome: a comparison of octreotide and midodrine.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20061201

Title: Midodrine for the treatment of vasovagal syncope (simple faint).

Journal: The Journal of pediatrics 20061201

Title: The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope.

Journal: The Journal of pediatrics 20061201

Title: The role of psychological factors in response to treatment in neurocardiogenic (vasovagal) syncope.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20060801

Title: Massive increase in proteinuria after the introduction of midodrine in an elderly patient-a case report.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Transport characteristics of a novel peptide transporter 1 substrate, antihypotensive drug midodrine, and its amino acid derivatives.

Journal: The Journal of pharmacology and experimental therapeutics 20060701

Title: Neurocardiogenic syncope: latest pharmacological therapies.

Journal: Expert opinion on pharmacotherapy 20060601

Title: Akathisia with combined use of midodrine and promethazine.

Journal: JAMA 20060503

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Why is orthostatic tolerance lower in women than in men? Renal and cardiovascular responses to simulated microgravity and the role of midodrine.

Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20060501

Title: Stress induced hypotension in pure autonomic failure.

Journal: Journal of neurology, neurosurgery, and psychiatry 20060401

Title: Pyridostigmine treatment trial in neurogenic orthostatic hypotension.

Journal: Archives of neurology 20060401

Title: Diagnosis and management of patients with blackouts.

Journal: Heart (British Cardiac Society) 20060401

Title: Hemodynamic effects of midodrine after spaceflight in astronauts without orthostatic hypotension.

Journal: Aviation, space, and environmental medicine 20060401

Title: Orthostatic hypotension in the nursing home setting.

Journal: Journal of the American Medical Directors Association 20060301

Title: Alcoholic cirrhosis-associated hepatorenal syndrome treated with vasoactive agents.

Journal: Nature clinical practice. Nephrology 20060301

Title: Liquid chromatography-tandem mass spectrometry method for the quantification of deglymidodrine in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: [Comparative efficacy and tolerance of atenolol and midodrine in patients with vasovagal syncopes].

Journal: Terapevticheskii arkhiv 20060101

Title: Beneficial haemodynamic and renal sodium handling effects of combined midodrine and octreotide treatment in a cirrhotic patient with large hepatic hydrothorax and mild ascites.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051101

Title: Effect of mineralocorticoids on interdialytic weight gain in hemodialysis patients with perdialytic hypotension.

Journal: Hemodialysis international. International Symposium on Home Hemodialysis 20051001

Title: Fludrocortisone in patients with familial dysautonomia--assessing effect on clinical parameters and gene expression.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20050801

Title: Adrenergic drugs for urinary incontinence in adults.

Journal: The Cochrane database of systematic reviews 20050720

Title: Adverse drug reactions related to drugs used in orthostatic hypotension: a prospective and systematic pharmacovigilance study in France.

Journal: European journal of clinical pharmacology 20050701

Title: Effects of therapy based on tilt testing results on the long-term outcome in patients with syncope.

Journal: Kardiologia polska 20050701

Title: [Diabetes mellitus and orthostatic intolerance].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050601

Title: Consequences of cardiovascular adaptation to spaceflight: implications for the use of pharmacological countermeasures.

Journal: Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology 20050601

Title: The effects of chronic treatment with octreotide versus octreotide plus midodrine on systemic hemodynamics and renal hemodynamics and function in nonazotemic cirrhotic patients with ascites.

Journal: The American journal of gastroenterology 20050401

Title: Successful treatment of hypotension associated with stunned myocardium with oral midodrine therapy.

Journal: Journal of cardiovascular pharmacology and therapeutics 20050301

Title: [Treatment of ejaculation disorders by midodrine (Gutron) per os. Retrospective study of about 16 subjects].

Journal: Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique 20050201

Title: [Treatment of ejaculation disorders].

Journal: Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique 20050201

Title: [Sjögren's syndrome with autonomic failure and epilepsy].

Journal: La Revue de medecine interne 20050201

Title: Treatment of vasodepressor carotid sinus syndrome with midodrine: a randomized, controlled pilot study.

Journal: Journal of the American Geriatrics Society 20050101

Title: Reconsidering hepatorenal syndrome. Throw in the towel? Not so fast!

Journal: Postgraduate medicine 20041201

Title: Postprandial hypotension treated with acarbose in a patient with type 1 diabetes mellitus.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20041201

Title: Effects of midodrine on exercise-induced hypotension and blood pressure recovery in autonomic failure.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041101

Title: Taste and smell disturbance with the alpha-adrenoceptor agonist midodrine.

Journal: The Annals of pharmacotherapy 20041101

Title: Midodrine appears to be safe and effective for dialysis-induced hypotension: a systematic review.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001

Title: A patient responding to combined therapy with pirmenol and midodrine for refractory neurally mediated syncope complicated by prostatic hypertrophy.

Journal: Cardiovascular drugs and therapy 20040901

Title: Chiral investigation of midodrine, a long-acting alpha-adrenergic stimulating agent.

Journal: Chirality 20040701

Title: Midodrine, octreotide, albumin, and TIPS in selected patients with cirrhosis and type 1 hepatorenal syndrome.

Journal: Hepatology (Baltimore, Md.) 20040701

Title: Midodrine prescribed to improve recurrent post-spaceflight orthostatic hypotension.

Journal: Aviation, space, and environmental medicine 20040601

Title: Intestinal obstruction associated with oral midodrine.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20040601

Title: Midodrine treatment for chronic fatigue syndrome.

Journal: Postgraduate medical journal 20040401

Title: Clinical history.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20040201

Title: Dysautonomia in chronic fatigue syndrome: facts, hypotheses, implications.

Journal: Medical hypotheses 20040101

Title: [Results of midodrin treatment of vasovagal syncope].

Journal: Terapevticheskii arkhiv 20040101

Title: Double-blinded, placebo-controlled trial of midodrine for exercise performance enhancement in tetraplegia: a pilot study.

Journal: The journal of spinal cord medicine 20040101

Title: The in vitro metabolism of desglymidodrine, an active metabolite of prodrug midodrine by human liver microsomes.

Journal: European journal of drug metabolism and pharmacokinetics 20040101

Title: [Successful midodrin treatment for vasovagal syncopes accompanied by asystole].

Journal: Klinicheskaia meditsina 20040101

Title: Effects of fatty acids and iontophoresis on the delivery of midodrine hydrochloride and the structure of human skin.

Journal: Pharmaceutical research 20031001

Title: [Blood pressure disorders during idiopathic Parkinson's disease].

Journal: Presse medicale (Paris, France : 1983) 20030809

Title: Midodrine improves chronic hypotension in hemodialysis patients.

Journal: The American journal of the medical sciences 20030501

Title: Recurrent syncope in a patient after myocardial infarction.

Journal: Pacing and clinical electrophysiology : PACE 20030401

Title: Determination of midodrine in human plasma by high-performance liquid chromatography with fluorescence detection.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201

Title: Atrial septal aneurysm with right-to-left interatrial shunting.

Journal: Texas Heart Institute journal 20030101

Title: Adrenergic drugs for urinary incontinence in adults.

Journal: The Cochrane database of systematic reviews 20030101

Title: Successful treatment of chronic fatigue syndrome with midodrine: a pilot study.

Journal: Clinical and experimental rheumatology 20030101

Title: A pilot randomized trial of induced blood pressure elevation: effects on function and focal perfusion in acute and subacute stroke.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20030101

Title: Efficacy and safety of midodrine in the treatment of dialysis-associated hypotension.

Journal: Expert opinion on drug safety 20030101

Title: Supine hypertension during general anesthesia in a patient taking midodrine.

Journal: Anesthesia and analgesia 20021101

Title: Midodrine, an alternative to intravenous vasopressor therapy after spinal surgery.

Journal: European journal of anaesthesiology 20021101

Title: N-[3-(1H-imidazol-4-ylmethyl)phenyl]ethanesulfonamide (ABT-866, 1),(1) a novel alpha(1)-adrenoceptor ligand with an enhanced in vitro and in vivo profile relative to phenylpropanolamine and midodrine.

Journal: Journal of medicinal chemistry 20020926

Title: Midodrine in neurally mediated syncope: a double-blind, randomized, crossover study.

Journal: Annals of neurology 20020901

Title: [Effects of midodrine on symptomatic hypotension during hemodialysis].

Journal: Revista medica de Chile 20020901

Title: Pandysautonomia associated with impaired ganglionic neurotransmission and circulating antibody to the neuronal nicotinic receptor.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20020801

Title: Unusual causes of severe orthostatic hypotension.

Journal: Hospital medicine (London, England : 1998) 20020401

Title: Recurrent syncope in a 31-year-old army staff sergeant.

Journal: Military medicine 20020301

Title: Hemodynamics in patients with intradialytic hypotension treated with cool dialysate or midodrine.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

Title: [Vasoconstrictors in the treatment of hepatorenal syndrome].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20020101

Title: Computer systems analysis of the cardiovascular mechanisms of reentry orthostasis in astronauts.

Journal: Computers in cardiology 20020101

Title: Caudate hemorrhage as a possible complication of midodrine-induced supine hypertension.

Journal: Mayo Clinic proceedings 20011201

Title: [Pharmacologic stimulation of ejaculation with midodrine hydrochloride (Gutron) for medically assisted reproduction in spinal injury].

Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20011201

Title: Pharmacologic options available to treat symptomatic intradialytic hypotension.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001

Title: Contingent negative variation in children with orthostatic dysregulation.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20011001

Title: Treatment of erectile dysfunction with sildenafil citrate (Viagra) in parkinsonism due to Parkinson's disease or multiple system atrophy with observations on orthostatic hypotension.

Journal: Journal of neurology, neurosurgery, and psychiatry 20010901

Title: Usefulness of midodrine in patients with severely symptomatic neurocardiogenic syncope: a randomized control study.

Journal: Journal of cardiovascular electrophysiology 20010801

Title: Use of midodrine (Gutron) to treat permanent hypotension in a chronic hemodialysis patient.

Journal: Clinical nephrology 20010801

Title: Efficacy and safety of midodrine hydrochloride in patients with refractory vasovagal syncope.

Journal: The American journal of cardiology 20010701

Title: Midodrine prevents orthostatic intolerance associated with simulated spaceflight.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010601

Title: Midodrine for the management of orthostatic hypotension in patients with spinal cord injury: A case report.

Journal: Archives of physical medicine and rehabilitation 20010501

Title: Syncope in pharmacologically unmasked Brugada syndrome: indication for an implantable defibrillator or an unresolved dilemma?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20010401

Title: Treatment of Severe Intradialytic Hypotension With the Addition of High Dialysate Calcium Concentration to Midodrine and/or Cool Dialysate.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010201

Title: Effect of midodrine on chlorpromazine-induced orthostatic hypotension in rabbits: comparison with amezinium, etilefrine and droxidopa.

Journal: Biological & pharmaceutical bulletin 20001201

Title: Acute dystonia induced by adding midodrine, a selective alpha 1 agonist, to risperidone in a patient with catatonic schizophrenia.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20000101

Title: Randomized double-blind placebo-controlled multicenter evaluation of efficacy and dose finding of midodrine hydrochloride in women with mild to moderate stress urinary incontinence: a phase II study.

Journal: International urogynecology journal and pelvic floor dysfunction 19980101

Title: Intradialytic hypotension: is midodrine beneficial in symptomatic hemodialysis patients?

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 19971201

Title: Midodrine for TCA-induced orthostatic hypotension.

Journal: Journal of psychiatry & neuroscience : JPN 19931101

Title: Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers.

Journal: International angiology : a journal of the International Union of Angiology 19930601

Title: Midodrine. A review of its pharmacological properties and therapeutic use in orthostatic hypotension and secondary hypotensive disorders.

Journal: Drugs 19891101

Title: [Treatment of hypotension caused by psychopharmacological drugs (author's transl)].

Journal: Wiener medizinische Wochenschrift (1946) 19810227

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Tags:3092-17-9 Molecular Formula|3092-17-9 MDL|3092-17-9 SMILES|3092-17-9 Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-,monohydrochloride, (±)-