Home Other Building Blocks 321661-62-5
321661-62-5,MFCD12912406
Catalog No.:AA019ELY

321661-62-5 | Cytosporone B

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
98%
in stock  
$16.00   $11.00
- +
5mg
98%
in stock  
$27.00   $19.00
- +
25mg
98%
in stock  
$70.00   $49.00
- +
50mg
98%
in stock  
$115.00   $81.00
- +
250mg
98%
in stock  
$494.00   $346.00
- +
1g
98%
in stock  
$1,158.00   $811.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA019ELY
Chemical Name:
Cytosporone B
CAS Number:
321661-62-5
Molecular Formula:
C18H26O5
Molecular Weight:
322.3960
MDL Number:
MFCD12912406
SMILES:
CCCCCCCC(=O)c1c(O)cc(cc1CC(=O)OCC)O
Properties
Properties
 
BP:
471.6±24.0 °C(Predicted)  
Form:
Solid  
Solubility:
DMSO: >20mg/mL  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
368  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
4.6  

Literature

Title: Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.

Journal: Marine drugs 20120401

Title: Targeting NR4A1 (TR3) in cancer cells and tumors.

Journal: Expert opinion on therapeutic targets 20110201

Title: A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro.

Journal: Cancer research 20100501

Title: Cytosporone B is an agonist for nuclear orphan receptor Nur77.

Journal: Nature chemical biology 20080901

Title: Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.

Journal: The Journal of biological chemistry 20050513

Title: The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway.

Journal: Cell 20030613

Title: Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors.

Journal: Nature 20030529

Title: Zhan Y, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008 Sep;4(9):548-56.

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SDS
Tags:321661-62-5 Molecular Formula|321661-62-5 MDL|321661-62-5 SMILES|321661-62-5 Cytosporone B