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3321-03-7,MFCD00065110
Catalog No.:AA003QQ5

3321-03-7 | Glycyl-l-phenylalanine

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250mg
95%
in stock  
$9.00   $7.00
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1g
95%
in stock  
$21.00   $15.00
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5g
95%
in stock  
$76.00   $54.00
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10g
95%
in stock  
$134.00   $94.00
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100g
95%
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$870.00   $609.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003QQ5
Chemical Name:
Glycyl-l-phenylalanine
CAS Number:
3321-03-7
Molecular Formula:
C11H14N2O3
Molecular Weight:
222.2405
MDL Number:
MFCD00065110
SMILES:
NCC(=O)N[C@H](C(=O)O)Cc1ccccc1
Properties
Properties
 
BP:
492.2°C at 760 mmHg  
Form:
Solid  
MP:
~264 °C (dec.)  
Refractive Index:
41 ° (C=2, H2O)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
250  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
-2.7  

Literature

Title: Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.

Journal: Molecular pharmaceutics 20120904

Title: Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).

Journal: PloS one 20120101

Title: Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity.

Journal: Journal of biomolecular screening 20110101

Title: A confocal study on the visualization of chromaffin cell secretory vesicles with fluorescent targeted probes and acidic dyes.

Journal: Journal of structural biology 20101201

Title: Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP.

Journal: The Biochemical journal 20100801

Title: Covalent immobilisation of protease and laccase substrates onto siloxanes.

Journal: Chemosphere 20100801

Title: The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction.

Journal: The Journal of biological chemistry 20100611

Title: Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.

Journal: Current biology : CB 20100427

Title: Calcium signaling via two-pore channels: local or global, that is the question.

Journal: American journal of physiology. Cell physiology 20100301

Title: Cellular locations of proteinases and association with vesicles in Porphyromonas gingivalis.

Journal: European journal of medical research 20100101

Title: Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Journal: Nature chemical biology 20090101

Title: Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20081101

Title: Riboflavin-binding protein is a novel bitter inhibitor.

Journal: Chemical senses 20080101

Title: Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length.

Journal: Bioscience, biotechnology, and biochemistry 20070801

Title: NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes.

Journal: The Journal of biological chemistry 20070629

Title: The lysosome or lysosome-related organelle may serve as a Ca2+ store in the boutons of hippocampal pyramidal cells.

Journal: Neuropharmacology 20070101

Title: Tuning the stacking properties of C3-symmetrical molecules by modifying a dipeptide motif.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.

Journal: Molecular and biochemical parasitology 20061201

Title: Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

Journal: Journal of medicinal chemistry 20060615

Title: Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes.

Journal: Cell calcium 20060201

Title: Cation-independent mannose 6-phosphate and 78 kDa receptors for lysosomal enzyme targeting are located in different cell compartments.

Journal: Biochimica et biophysica acta 20050815

Title: Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.

Journal: Biochemistry 20050802

Title: Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.

Journal: Biochemistry 20050802

Title: Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly.

Journal: Archives of biochemistry and biophysics 20050301

Title: Intrinsic folding of small peptide chains: spectroscopic evidence for the formation of beta-turns in the gas phase.

Journal: Journal of the American Chemical Society 20050119

Title: A yeast extract high in bioactive peptides has a blood-pressure lowering effect in hypertensive model.

Journal: Current medicinal chemistry 20050101

Title: Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040801

Title: Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver.

Journal: Biochemical and biophysical research communications 20020906

Title: Lysosomal Ca(2+) stores in bovine corneal endothelium.

Journal: Investigative ophthalmology & visual science 20020701

Title: Internalization and stepwise degradation of heparan sulfate proteoglycans in rat hepatocytes.

Journal: Biochimica et biophysica acta 20011219

Title: Lipopolysaccharide and phorbol 12-myristate 13-acetate both impair monocyte differentiation, relating cellular function to virus susceptibility.

Journal: Immunology 20010801

Title: Effects of methylcyclodextrin on lysosomes.

Journal: European journal of biochemistry 20010301

Title: Lanthanide ion-mediated peptide hydrolysis.

Journal: Metal ions in biological systems 20010101

Title: Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors.

Journal: Journal of medicinal chemistry 20000224

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