Title: Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent.
Journal: Bioresource technology 20120801
Title: E2F1 enhances 8-chloro-adenosine-induced G2/M arrest and apoptosis in A549 and H1299 lung cancer cells.
Journal: Biochemistry. Biokhimiia 20120301
Title: Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
Journal: PloS one 20120101
Title: A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels.
Journal: Breast cancer research and treatment 20100601
Title: Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels.
Journal: The Journal of biological chemistry 20100312
Title: Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis.
Journal: British journal of haematology 20091101
Title: Inhibition of ATP synthase by chlorinated adenosine analogue.
Journal: Biochemical pharmacology 20090915
Title: Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells.
Journal: Biochemical pharmacology 20090301
Title: 8-Chloro-adenosine-induced E2F1 promotes p14ARF gene activation in H1299 cells through displacing Sp1 from multiple overlapping E2F1/Sp1 sites.
Journal: Journal of cellular biochemistry 20090215
Title: Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells.
Journal: Biochemical pharmacology 20090201
Title: Induction of p14ARF by E2F1 contributes to 8-chloro-adenosine-induced apoptosis in human lung cancer H1299 cells.
Journal: Chemotherapy 20090101
Title: Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine.
Journal: The Journal of clinical endocrinology and metabolism 20080301
Title: Multiple myeloma cell killing by depletion of the MET receptor tyrosine kinase.
Journal: Cancer research 20071015
Title: 8-Chloro-adenosine inhibits growth at least partly by interfering with actin polymerization in cultured human lung cancer cells.
Journal: Biochemical pharmacology 20060828
Title: 8-chloroadenosine induced HL-60 cell growth inhibition, differentiation, and G(0)/G(1) arrest involves attenuated cyclin D1 and telomerase and up-regulated p21(WAF1/CIP1).
Journal: Journal of cellular biochemistry 20060101
Title: The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro.
Journal: Investigational new drugs 20060101
Title: [Mechanisms of sensitization by 8-chloro-adenosine of human tumor cells to TRAIL-induced apoptosis].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20051001
Title: 8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells.
Journal: Cancer research 20050601
Title: [Preparation of 8-chloro-adenosine long circulation liposomes and its pharmacokinetics in rats].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050401
Title: 8-Cl-cAMP and its metabolite, 8-Cl-adenosine induce growth inhibition in mouse fibroblast DT cells through the same pathways: protein kinase C activation and cyclin B down-regulation.
Journal: Journal of cellular physiology 20041101
Title: 8-Chloro-adenosine sensitizes a human hepatoma cell line to TRAIL-induced apoptosis by caspase-dependent and -independent pathways.
Journal: Oncology reports 20040701
Title: [Inhibition of 8-chloroadenosine on proteasome activity of HL-60 cells].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20040201
Title: Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides.
Journal: Nucleosides, nucleotides & nucleic acids 20040101
Title: 8-Cl-Adenosine enhances 1,25-dihydroxyvitamin D3-induced growth inhibition without affecting 1,25-dihydroxyvitamin D3-stimulated differentiation of primary mouse epidermal keratinocytes.
Journal: BMC pharmacology 20040101
Title: [The inhibitory effect of 8-chloroadenosine on tumor necrosis factor-induced proto-oncogene expression of retinal pigment epithelial cells].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20031201
Title: RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells.
Journal: Cancer research 20031115
Title: [8-Chloro-adenosine increases the activity of transcription factor CREB by modification of phosphorylation].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20030401
Title: Anti-proliferative effects of 8-chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression.
Journal: Journal of cellular physiology 20020801
Title: Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats.
Journal: Cancer chemotherapy and pharmacology 20020801
Title: Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray.
Journal: Experimental & molecular medicine 20020731
Title: Synthesis and hybridization properties of RNA containing 8-chloroadenosine.
Journal: Nucleosides, nucleotides & nucleic acids 20020101
Title: 8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs.
Journal: Cancer chemotherapy and pharmacology 20011201
Title: 8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells.
Journal: Cancer research 20010715
Title: 8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblastic leukemia cells to TNFalpha-induced apoptosis is via inactivation of NF-kappaB.
Journal: Leukemia research 20010501