Home Pyridines 350-03-8
350-03-8,MFCD00006396
Catalog No.:AA003IQQ

350-03-8 | 3-Acetylpyridine

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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003IQQ
Chemical Name:
3-Acetylpyridine
CAS Number:
350-03-8
Molecular Formula:
C7H7NO
Molecular Weight:
121.1366
MDL Number:
MFCD00006396
SMILES:
CC(=O)c1cccnc1
NSC Number:
761
FEMA Number:
3424
Properties
Properties
 
BP:
220.8°C at 760 mmHg  
Form:
Liquid  
MP:
11-13 °C(lit.)  
Refractive Index:
n20/D 1.534(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
112  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
0.4  

Literature

Title: 3-Acetylpyridine neurotoxicity in mice.

Journal: Neurotoxicology 20170101

Title: The synthesis, spectroscopic, X-ray characterization and in vitro cytotoxic testing results of activity of five new trans-platinum(IV) complexes with functionalized pyridines.

Journal: European journal of medicinal chemistry 20120901

Title: Bis(3-acetyl-pyridine-κN)diaqua-bis-(seleno-cyanato-κN)cobalt(II).

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: catena-Poly[[bis-(3-acetyl-pyridine-κN)cadmium]-di-μ-seleno-cyanato-κ(2)N:Se;κ(2)Se:N].

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Morphology of single olivocerebellar axons in the denervation-reinnervation model produced by subtotal lesion of the rat inferior olive.

Journal: Brain research 20120417

Title: Synthesis, antimicrobial and anticancer activities of a novel series of diphenyl 1-(pyridin-3-yl)ethylphosphonates.

Journal: Bioorganic & medicinal chemistry 20120401

Title: Bis(3-acetyl-pyridine-κN)bis-(methanol-κO)bis-(thio-cyanato-κN)nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure.

Journal: Journal of inorganic biochemistry 20120301

Title: Behavioural significance of cerebellar modules.

Journal: Cerebellum (London, England) 20110901

Title: Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children.

Journal: The Journal of infectious diseases 20110701

Title: Profound alterations in the intrinsic excitability of cerebellar Purkinje neurons following neurotoxin 3-acetylpyridine (3-AP)-induced ataxia in rat: new insights into the role of small conductance K+ channels.

Journal: Physiological research 20110101

Title: Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex.

Journal: PloS one 20110101

Title: FKBP51 protects 661w cell culture from staurosporine-induced apoptosis.

Journal: Molecular vision 20110101

Title: Age sensitivity of behavioral tests and brain substrates of normal aging in mice.

Journal: Frontiers in aging neuroscience 20110101

Title: Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43.

Journal: PloS one 20110101

Title: Steroidogenic acute regulatory protein expression in the central nervous system.

Journal: Frontiers in endocrinology 20110101

Title: Novel synthesis of hydrazide-hydrazone derivatives and their utilization in the synthesis of coumarin, pyridine, thiazole and thiophene derivatives with antitumor activity.

Journal: Molecules (Basel, Switzerland) 20101223

Title: Didymosphaeria igniaria: a new microorganism useful for the enantioselective reduction of aryl-aliphatic ketones.

Journal: Journal of industrial microbiology & biotechnology 20101101

Title: In vivo 4-aminopyridine treatment alters the neurotoxin 3-acetylpyridine-induced plastic changes in intrinsic electrophysiological properties of rat cerebellar Purkinje neurones.

Journal: European journal of pharmacology 20100910

Title: Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii.

Journal: PLoS genetics 20100901

Title: Ruthenium(II)-arene complexes with functionalized pyridines: synthesis, characterization and cytotoxic activity.

Journal: European journal of medicinal chemistry 20100301

Title: Multi-photon nanosurgery in live brain.

Journal: Frontiers in neuroenergetics 20100101

Title: Dendritic spines and development: towards a unifying model of spinogenesis--a present day review of Cajal's histological slides and drawings.

Journal: Neural plasticity 20100101

Title: Chemical, structural and biological studies of cis-[Pt(3-Acpy)(2)Cl(2)].

Journal: Journal of inorganic biochemistry 20090901

Title: Novel trans-dichloridoplatinum(II) complexes with 3- and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity.

Journal: European journal of medicinal chemistry 20090501

Title: Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence.

Journal: Neurotoxicology 20090501

Title: Poly[[diaqua-{N-[1-(3-pyrid-yl)ethyl-idene]-4H-1,2,4-triazol-4-amine}zinc(II)] bis-(perchlorate)].

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: 3-(3,4-Dimethoxy-phenyl)-1-(3-pyridyl)prop-2-en-1-one monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: 3-[4-(Dimethyl-amino)phenyl]-1-(3-pyridyl)prop-2-en-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

Journal: PloS one 20090101

Title: Thyrotropin-releasing hormone (TRH) in the cerebellum.

Journal: Cerebellum (London, England) 20080101

Title: FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.

Journal: Genome biology 20080101

Title: Pontocerebellar hypoplasia type 2: a neuropathological update.

Journal: Acta neuropathologica 20071001

Title: [Astragalus membranaceus promote expression of insulin-like growth factor 1 in rat model of olivo-cerebellar degeneration].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201

Title: Intensive remodeling of Purkinje cell spines after climbing fibers deafferentation does not involve MAPK and Akt activation.

Journal: Annals of the New York Academy of Sciences 20070101

Title: Development of a novel 99mTc-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061201

Title: trans-Bis(3-acetylpyridine-kappaN)diiodoplatinum(II).

Journal: Acta crystallographica. Section C, Crystal structure communications 20061201

Title: Episodic vestibular disruption following ablation of the inferior olive in rats: behavioral correlates.

Journal: Behavioural brain research 20061125

Title: Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway.

Journal: The European journal of neuroscience 20061001

Title: Chain mechanism in the photocleavage of phenacyl and pyridacyl esters in the presence of hydrogen donors.

Journal: The Journal of organic chemistry 20060120

Title: Cyanoacetic acid hydrazones of 3-(and 4-)acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents.

Journal: Archiv der Pharmazie 20060101

Title: Purification and characterization of rat liver enzyme catalyzing stereoselective reduction of acetylpyridines.

Journal: Chirality 20051001

Title: Differential effects of trans-crotononitrile and 3-acetylpyridine on inferior olive integrity and behavioural performance in the rat.

Journal: The European journal of neuroscience 20050801

Title: Spontaneous electrical activity and dendritic spine size in mature cerebellar Purkinje cells.

Journal: The European journal of neuroscience 20050401

Title: Defective control and adaptation of reflex eye movements in mutant mice deficient in either the glutamate receptor delta2 subunit or Purkinje cells.

Journal: The European journal of neuroscience 20050301

Title: New enzymatic assay, parasite lactate dehydrogenase, in diagnosis of malaria in Kenya.

Journal: East African medical journal 20050301

Title: AgI and CuI binuclear macrocyclic complexes with 1-(3-pyridyl)ethanone oxime.

Journal: Acta crystallographica. Section C, Crystal structure communications 20040101

Title: Olivocerebellar projections are necessary for exogenous trophic factors to delay heredo-Purkinje cell degeneration.

Journal: Brain research 20031003

Title: Attenuation of activity-induced increases in cerebellar blood flow by lesion of the inferior olive.

Journal: American journal of physiology. Heart and circulatory physiology 20030901

Title: Endogenous estrogen formation is neuroprotective in model of cerebellar ataxia.

Journal: Endocrine 20030601

Title: Glutamate receptor delta2 subunit in activity-dependent heterologous synaptic competition.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315

Title: Differential distribution of vesicular glutamate transporters in the rat cerebellar cortex.

Journal: Neuroscience 20030101

Title: Comparative effects of lesions to the ponto-cerebellar and olivo-cerebellar pathways on motor and spatial learning in the rat.

Journal: Neuroscience 20030101

Title: PSA-NCAM immunocytochemistry in the cerebral cortex and other telencephalic areas of the lizard Podarcis hispanica: differential expression during medial cortex neuronal regeneration.

Journal: The Journal of comparative neurology 20021111

Title: The neuroimmunophilin GPI-1046 partially protects against 3-acetylpyridine toxicity in the rat.

Journal: Neuroscience letters 20020315

Title: HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption.

Journal: Gene therapy 20020201

Title: Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes.

Journal: Bioconjugate chemistry 20020101

Title: [Effect of nicotinamide adenine dinucleotide on the serotoninergic mediator system in the rat brain during 3-acetylpyridine administration].

Journal: Voprosy meditsinskoi khimii 20020101

Title: 3-acetylpyridine reduces tongue protrusion force but does not abolish lick rhythm in the rat.

Journal: Brain research 20011130

Title: Detecting necrotic neurons with fluoro-jade stain.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20011001

Title: Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801

Title: Spectral studies of semicarbazones derived from 3- and 4-formylpyridine and 3- and 4-acetylpyridine: crystal and molecular structure of 3-formylpyridine semicarbazone.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010801

Title: Maintenance of connexin 32 and 26 expression in primary cultured rat hepatocytes treated with 3-acetylpyridine.

Journal: Journal of gastroenterology and hepatology 20010701

Title: NK cytotoxic activity and relative distribution of NK cells in 3-acetylpyridine influenced mice.

Journal: Folia microbiologica 20010101

Title: Adrenergic agents inhibit rapid increases in cerebellar Purkinje cell glutamic acid decarboxylase (GAD67) mRNA levels after climbing fiber lesions or reserpine treatment.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19960301

Title: Strychnine seizure potentiation by azaspirodecanedione anxiolytics in rats.

Journal: European journal of pharmacology 19881018

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Tags:350-03-8 Molecular Formula|350-03-8 MDL|350-03-8 SMILES|350-03-8 3-Acetylpyridine |Heterocyclic_Building_Blocks