Title: Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages.
Journal: The Journal of biological chemistry 20160520
Title: Poly(ADP-ribosyl)ation enhances H-RAS protein stability and causes abnormal cell cycle progression in human TK6 lymphoblastoid cells treated with hydroquinone.
Journal: Chemico-biological interactions 20150805
Title: A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Journal: Cell metabolism 20141104
Title: Inhibition of poly(ADP-ribose) polymerase attenuates acute kidney injury in sodium taurocholate-induced acute pancreatitis in rats.
Journal: Pancreas 20121101
Title: NGF promotes long-term memory formation by activating poly(ADP-ribose)polymerase-1.
Journal: Neuropharmacology 20121101
Title: Genotoxic stress and activation of novel DNA repair enzymes in human endothelial cells and in the retinas and kidneys of streptozotocin diabetic rats.
Journal: Diabetes/metabolism research and reviews 20120501
Title: Increased poly(ADP-ribosyl)ation in peripheral leukocytes and the reperfused myocardium tissue of rats with ischemia/reperfusion injury: prevention by 3-aminobenzamide treatment.
Journal: Shock (Augusta, Ga.) 20120501
Title: Poly(ADP-ribose) polymerase inhibition improves erectile function by activation of nitric oxide/cyclic guanosine monophosphate pathway in diabetic rats.
Journal: The journal of sexual medicine 20120501
Title: Preventive Effect of Cichorium Intybus L. Two Extracts on Cerulein-induced Acute Pancreatitis in Mice.
Journal: International journal of preventive medicine 20120501
Title: 3'-5' phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo.
Journal: The Biochemical journal 20120415
Title: Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors.
Journal: European journal of medicinal chemistry 20120401
Title: Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
Journal: Biochemical pharmacology 20120315
Title: Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure.
Journal: Journal of inorganic biochemistry 20120301
Title: Novel pathway of centrosome amplification that does not require DNA lesions.
Journal: Cancer science 20120201
Title: ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites.
Journal: The Biochemical journal 20120115
Title: Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli.
Journal: PLoS genetics 20120101
Title: Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema.
Journal: Journal of inflammation (London, England) 20120101
Title: Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV.
Journal: Frontiers in microbiology 20120101
Title: Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs.
Journal: Journal of biomedical science 20120101
Title: Adaptive response in mice exposed to 900 MHz radiofrequency fields: primary DNA damage.
Journal: PloS one 20120101
Title: Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells.
Journal: Journal of biomedical science 20120101
Title: Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3.
Journal: International journal of molecular sciences 20120101
Title: Chemical PARP inhibition enhances growth of Arabidopsis and reduces anthocyanin accumulation and the activation of stress protective mechanisms.
Journal: PloS one 20120101
Title: [Suppressing poly(ADP-ribose)polymerase-1 inhibits tau phosphorylation in HEK293/tau441 cells].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20111225
Title: Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride.
Journal: Journal of enzyme inhibition and medicinal chemistry 20111201
Title: Chemotherapy sensitivity recovery of prostate cancer cells by functional inhibition and knock down of multidrug resistance proteins.
Journal: The Prostate 20111201
Title: Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity.
Journal: Molecular and cellular biochemistry 20111201
Title: Morphological and functional evaluation of an animal model for the retinal degeneration induced by N-methyl-N-nitrosourea.
Journal: Anatomy & cell biology 20111201
Title: Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft.
Journal: Molecular cancer therapeutics 20111001
Title: Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis.
Journal: Mutagenesis 20110901
Title: PARP1 inhibitors attenuate AKT phosphorylation via the upregulation of PHLPP1.
Journal: Biochemical and biophysical research communications 20110826
Title: Association of sperm morphology and the sperm deformity index (SDI) with poly (ADP-ribose) polymerase (PARP) cleavage inhibition.
Journal: Fertility and sterility 20110630
Title: PARP inhibition prevents oxidative injury of bladder induced by acute urinary retention and subsequent emptying.
Journal: Apoptosis : an international journal on programmed cell death 20110601
Title: [Effect of erythropoietin on proinflammatory factors of human monocytes and its mechanisms].
Journal: Zhongguo shi yan xue ye xue za zhi 20110601
Title: Perinatal asphyxia: current status and approaches towards neuroprotective strategies, with focus on sentinel proteins.
Journal: Neurotoxicity research 20110501
Title: Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity.
Journal: Neurochemical research 20110501
Title: The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells.
Journal: Oncology reports 20110501
Title: Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.
Journal: Journal of medicinal chemistry 20110414
Title: Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death.
Journal: Cellular and molecular life sciences : CMLS 20110401
Title: PARP inhibition restores erectile function by suppressing corporal smooth muscle apoptosis in diabetic rats.
Journal: The journal of sexual medicine 20110401
Title: Synthesis and preliminary evaluation of selected 2-aryl-5(6)-nitro- 1H-benzimidazole derivatives as potential anticancer agents.
Journal: Archives of pharmacal research 20110201
Title: Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity.
Journal: Free radical biology & medicine 20110101
Title: Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks.
Journal: Genome integrity 20110101
Title: The CCCTC-binding factor (CTCF) of Drosophila contributes to the regulation of the ribosomal DNA and nucleolar stability.
Journal: PloS one 20110101
Title: LRP16 integrates into NF-κB transcriptional complex and is required for its functional activation.
Journal: PloS one 20110101
Title: Recombination phenotypes of the NCI-60 collection of human cancer cells.
Journal: BMC molecular biology 20110101
Title: Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2.
Journal: Vascular cell 20110101
Title: Promising molecular targeted therapies in breast cancer.
Journal: Indian journal of pharmacology 20110101
Title: Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.
Journal: PloS one 20110101
Title: Poly(ADP-ribose) polymerase 1 is indispensable for transforming growth factor-β Induced Smad3 activation in vascular smooth muscle cell.
Journal: PloS one 20110101
Title: Hepatoprotective effects of select water-soluble PARP inhibitors in a carbon tetrachloride model.
Journal: International journal of critical illness and injury science 20110101
Title: Effects of 3-aminobenzamide on unilateral testicular ischemia-reperfusion injury: what is the role of PARP inhibition?
Journal: Canadian journal of physiology and pharmacology 20101201
Title: Increased levels of p53 and PARP-1 in EL-4 cells probably related with the immune adaptive response induced by low dose ionizing radiation in vitro.
Journal: Biomedical and environmental sciences : BES 20101201
Title: Targeting poly(ADP-ribose) polymerase activity for cancer therapy.
Journal: Cellular and molecular life sciences : CMLS 20101101
Title: Dietary t10,c12-CLA but not c9,t11 CLA reduces adipocyte size in the absence of changes in the adipose renin-angiotensin system in fa/fa Zucker rats.
Journal: Lipids 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Poly(ADP-ribose) polymerase inhibitor, 3-aminobenzamide, protects against experimental immune ovarian failure in mice.
Journal: Reproductive biology 20101101
Title: Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.
Journal: Aging 20101001
Title: Diabetic cystopathy is associated with PARP/JNK/mitochondrial apoptotic pathway-mediated bladder apoptosis.
Journal: Neurourology and urodynamics 20100901
Title: Nickel modifies the cytotoxicity of hexavalent chromium in human dermal fibroblasts.
Journal: Toxicology letters 20100816
Title: Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway.
Journal: Science (New York, N.Y.) 20100702
Title: Fertilization capacity with rainbow trout DNA-damaged sperm and embryo developmental success.
Journal: Reproduction (Cambridge, England) 20100601
Title: Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats.
Journal: Journal of neurotrauma 20100601
Title: Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine.
Journal: European journal of pharmacology 20100310
Title: Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.
Journal: Biochemistry 20100216
Title: Discovery and SAR of novel, potent and selective hexahydrobenzonaphthyridinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
Journal: Bioorganic & medicinal chemistry letters 20100115
Title: Disruption of poly(ADP-ribosyl)ation mechanisms alters responses of Arabidopsis to biotic stress.
Journal: Plant physiology 20100101
Title: PISA, a novel pharmacodynamic assay for assessing poly(ADP-ribose) polymerase (PARP) activity in situ.
Journal: Journal of pharmacological and toxicological methods 20100101
Title: BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer.
Journal: Journal of oncology 20100101
Title: Relationship between DNA repair and formation of sister chromatid exchanges and chromatid aberrations under the influence of poly(ADP-ribose) polymerase inhibition by 3-aminobenzamide.
Journal: Cytogenetic and genome research 20100101
Title: Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites.
Journal: PloS one 20100101
Title: A novel PARP inhibitor L-2286 in a rat model of impact acceleration head injury: an immunohistochemical and behavioral study.
Journal: International journal of molecular sciences 20100101
Title: Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy.
Journal: PloS one 20100101
Title: Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability.
Journal: Genome integrity 20100101
Title: Clioquinol inhibits zinc-triggered caspase activation in the hippocampal CA1 region of a global ischemic gerbil model.
Journal: PloS one 20100101
Title: Role of nicotinamide in DNA damage, mutagenesis, and DNA repair.
Journal: Journal of nucleic acids 20100101
Title: Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide.
Journal: Journal of biomedical science 20100101
Title: PolyADP-ribosylation is required for pronuclear fusion during postfertilization in mice.
Journal: PloS one 20100101
Title: Targeting the osteosarcoma cancer stem cell.
Journal: Journal of orthopaedic surgery and research 20100101
Title: Effects of inosine on reperfusion injury after cardiopulmonary bypass.
Journal: Journal of cardiothoracic surgery 20100101
Title: PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.
Journal: PloS one 20100101
Title: BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide.
Journal: Gynecologic oncology 20091101
Title: Inhibition of matrix metalloproteinase-2 by PARP inhibitors.
Journal: Biochemical and biophysical research communications 20091002
Title: Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway.
Journal: Molecular pharmacology 20091001
Title: Poly (ADP-Ribose) polymerase inhibition attenuates atherosclerotic plaque development in ApoE-/- mice with hyperhomocysteinemia.
Journal: Journal of atherosclerosis and thrombosis 20091001
Title: Multiple mechanisms for hydrogen peroxide-induced apoptosis.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Poly-(ADP-ribose) polymerase-1 is necessary for long-term facilitation in Aplysia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090729
Title: Effects of 3-aminobenzamide on expressions of poly (ADP ribose) polymerase and apoptosis inducing factor in cardiomyocytes of rats with acute myocardial infarction.
Journal: Chinese medical journal 20090605
Title: Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells.
Journal: Biology of the cell 20090604
Title: Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
Journal: Apoptosis : an international journal on programmed cell death 20090601
Title: Roles of inhibitors of poly(ADP-ribose) polymerase in protecting rat RINm5F cell line against free fatty acid-induced apoptosis.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20090601
Title: Evaluation of poly(ADP-ribose) polymerase cleavage (cPARP) in ejaculated human sperm fractions after induction of apoptosis.
Journal: Fertility and sterility 20090501
Title: Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment.
Journal: Journal of cellular physiology 20090501
Title: Diabetic cardiomyopathy.
Journal: Clinical science (London, England : 1979) 20090501
Title: Poly (ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by hyperhomocysteinemia in rats.
Journal: Cardiovascular drugs and therapy 20090401
Title: Inhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damage.
Journal: The Journal of biological chemistry 20090313
Title: Determination of Poly (ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation.
Journal: Fertility and sterility 20090301
Title: Does the 3-aminobenzamide effect on bacterial translocation affect experimental acute necrotizing pancreatitis?
Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20090301
Title: Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitors.
Journal: Journal of medicinal chemistry 20090212
Title: PARP-1 suppresses adiponectin expression through poly(ADP-ribosyl)ation of PPAR gamma in cardiac fibroblasts.
Journal: Cardiovascular research 20090101
Title: Structure-activity relationship analysis of cytotoxic cyanoguanidines: selection of CHS 828 as candidate drug.
Journal: BMC research notes 20090101
Title: Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer.
Journal: Breast cancer research : BCR 20090101
Title: Poly[ADP-ribose] polymerase-1 expression is related to cold ischemia, acute tubular necrosis, and delayed renal function in kidney transplantation.
Journal: PloS one 20090101
Title: 3-aminobenzamide, a poly ADP ribose polymerase inhibitor, attenuates renal ischemia/reperfusion injury.
Journal: Renal failure 20090101
Title: Microglial involvement in neuroplastic changes following focal brain ischemia in rats.
Journal: PloS one 20090101
Title: Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.
Journal: Reproductive biology and endocrinology : RB&E 20090101
Title: Systemic administration of lipopolysaccharide impairs glutathione redox state and object recognition in male mice. The effect of PARP-1 inhibitor.
Journal: Folia neuropathologica 20090101
Title: Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1.
Journal: Journal of cellular and molecular medicine 20081201
Title: Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity.
Journal: Toxicology and applied pharmacology 20081001
Title: The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.
Journal: PLoS biology 20081001
Title: Meta-iodobenzylguanidine, an inhibitor of arginine-dependent mono(ADP-ribosyl)ation, prevents neointimal hyperplasia.
Journal: The Journal of pharmacology and experimental therapeutics 20080901
Title: PARP mediates structural alterations in diabetic cardiomyopathy.
Journal: Journal of molecular and cellular cardiology 20080901
Title: CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.
Journal: The Journal of biological chemistry 20080808
Title: Ischemic and peroxynitrite preconditioning effects in chronic hypoxic rat lung.
Journal: Experimental lung research 20080801
Title: Effect of 3-amino benzamide, a poly(adenosine diphosphate-ribose) polymerase inhibitor, in experimental caustic esophageal burn.
Journal: Journal of pediatric surgery 20080801
Title: Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells.
Journal: Archives of toxicology 20080701
Title: Non-enzymatic fast repair of DNA oxidative damage might also exist in cells.
Journal: Cell biology international 20080601
Title: Oxidative stress-induced, poly(ADP-ribose) polymerase-dependent upregulation of ET-1 expression in chronic diabetic complications.
Journal: Canadian journal of physiology and pharmacology 20080601
Title: Induction of cytogenetic adaptive response in spermatogonia and spermatocytes by pre-exposure of mouse testis to low-dose (12)C(6+) ions.
Journal: Mutation research 20080531
Title: Poly(adp-ribose) polymerase-1 regulates Tracp gene promoter activity during RANKL-induced osteoclastogenesis.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080401
Title: 1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages.
Journal: Archivum immunologiae et therapiae experimentalis 20080401
Title: TcPARP: A DNA damage-dependent poly(ADP-ribose) polymerase from Trypanosoma cruzi.
Journal: International journal for parasitology 20080301
Title: Effects of poly(ADP-ribose) polymerase inhibition in bladder damage caused by cyclophosphamide in rats.
Journal: Experimental biology and medicine (Maywood, N.J.) 20080301
Title: Combinatorial-approached neuroprotection using pan-caspase inhibitor and poly (ADP-ribose) polymerase (PARP) inhibitor following experimental stroke in rats; is there additional benefit?
Journal: Brain research 20080221
Title: PARP activation and the alteration of vasoactive factors and extracellular matrix protein in retina and kidney in diabetes.
Journal: Diabetes/metabolism research and reviews 20080101
Title: Possible involvement of 12-lipoxygenase activation in glucose-deprivation/reload-treated neurons.
Journal: Neuroscience letters 20071218
Title: Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.
Journal: European journal of pharmacology 20071114
Title: Activation of telomerase by ionizing radiation: differential response to the inhibition of DNA double-strand break repair by abrogation of poly (ADP-ribosyl)ation, by LY294002, or by Wortmannin.
Journal: International journal of radiation oncology, biology, physics 20071101
Title: Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.
Journal: The Journal of nutrition 20071001
Title: Strain-dependent induction of epithelial cell oncosis by Campylobacter jejuni is correlated with invasion ability and is independent of cytolethal distending toxin.
Journal: Microbiology (Reading, England) 20070901
Title: Poly(ADP-ribose) polymerase inhibitor is neuroprotective in epileptic rat via apoptosis-inducing factor and Akt signaling.
Journal: Neuroreport 20070806
Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
Journal: Toxicology letters 20070801
Title: Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: a crucial role of tubulin deacetylation.
Journal: Neuroscience 20070713
Title: Xanthomonas caspase displays an inherent PARP-like activity.
Journal: FEMS microbiology letters 20070701
Title: Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1.
Journal: Experimental gerontology 20070601
Title: Enhanced poly(ADP-ribose) polymerase-1 activation contributes to recombinant tissue plasminogen activator-induced aggravation of ischemic brain injury in vivo.
Journal: Journal of neuroscience research 20070601
Title: Apoptosis in sulfur mustard treated A549 cell cultures.
Journal: Life sciences 20070530
Title: Combination therapy of poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells.
Journal: Journal of gastroenterology and hepatology 20070501
Title: Ischemia/reperfusion of the liver induces heart injury in rats.
Journal: Transplantation proceedings 20070501
Title: Oxidative stress-induced poly(ADP-ribosyl)ation in chick limb bud-derived chondrocytes.
Journal: International journal of molecular medicine 20070401
Title: PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070301
Title: The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair.
Journal: Biological & pharmaceutical bulletin 20070301
Title: Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide rescues N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity.
Journal: Experimental eye research 20070201
Title: Lactate down-regulates cellular poly(ADP-ribose) formation in cultured human skin fibroblasts.
Journal: European journal of clinical investigation 20070201
Title: Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells.
Journal: BMC genomics 20070101
Title: Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.
Journal: BMC molecular biology 20070101
Title: Poly(ADP-ribose) polymerase offers protection against oxidative and alkylation damage to the nuclear and mitochondrial genomes of the retinal pigment epithelium.
Journal: Ophthalmic research 20070101
Title: A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose.
Journal: Theoretical biology & medical modelling 20070101
Title: Inhibition of Poly(ADP-ribose)polymerase impairs Epstein Barr Virus lytic cycle progression.
Journal: Infectious agents and cancer 20070101
Title: [The influence of chemical inhibitors of DNA repair on the recovery of mammalian cell damages induced by ionizing radiation].
Journal: Radiatsionnaia biologiia, radioecologiia 20070101
Title: PARP inhibitors accelerate N-methyl-N-nitrosourea-induced cataractogenesis in Sprague-Dawley rats.
Journal: In vivo (Athens, Greece) 20070101
Title: GSK-3beta and oxidative stress in aged brain. Role of poly(ADP- -ribose) polymerase-1.
Journal: Folia neuropathologica 20070101
Title: [Poly(ADP-ribosa)polymerase--the relationships with life span and carcinogenesis].
Journal: Advances in gerontology = Uspekhi gerontologii 20070101
Title: Effects of poly(ADP-ribose) polymerase inhibition on dysfunction of non-adrenergic non-cholinergic neurotransmission in gastric fundus in diabetic rats.
Journal: Nitric oxide : biology and chemistry 20061201
Title: Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation.
Journal: Neurochemistry international 20061201
Title: Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Journal: Biochemical and biophysical research communications 20061201
Title: Molecular determinants involved in the increase of damage-induced apoptosis and delay of secondary necrosis due to inhibition of mono(ADP-ribosyl)ation.
Journal: Annals of the New York Academy of Sciences 20061201
Title: Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis.
Journal: Biochemical and biophysical research communications 20061117
Title: Effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, in a mouse model of acute pancreatitis induced by cerulein.
Journal: European journal of pharmacology 20061107
Title: Inhibition of poly(ADP-ribose)polymerase does not affect the recombination events in CHO xrs6 and wild type cells.
Journal: Radiation and environmental biophysics 20061101
Title: Preconditioning effects of peroxynitrite in the rat lung.
Journal: Pharmacological research 20061101
Title: Helicobacter pylori induces mono-(adenosine 5'-diphosphate)-ribosylation in human gastric adenocarcinoma.
Journal: International journal of oncology 20061001
Title: Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
Journal: European journal of medical research 20060830
Title: In vivo exposure of swiss albino mice to chronic low dose of dimethylnitrosamine (DMN) lowers poly-ADP-ribosylation (PAR) of bone marrow cell and blood lymphocyte proteins.
Journal: Molecular and cellular biochemistry 20060801
Title: Discovery and characterization of triaminotriazine aniline amides as highly selective p38 kinase inhibitors.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Adenosine2A receptor vasodilation of rat preglomerular microvessels is mediated by EETs that activate the cAMP/PKA pathway.
Journal: American journal of physiology. Renal physiology 20060701
Title: Hydrogen peroxide-mediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage.
Journal: Experimental cell research 20060610
Title: Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options.
Journal: Gastroenterology 20060601
Title: Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress.
Journal: Apoptosis : an international journal on programmed cell death 20060501
Title: Ex vivo modulation of response to prednisolone in childhood acute lymphoblastic leukaemia.
Journal: British journal of haematology 20060501
Title: The effects of tempol, 3-aminobenzamide and nitric oxide synthase inhibitors on acoustic injury of the mouse cochlea.
Journal: Hearing research 20060401
Title: Mechanism of rat mesenteric arterial KATP channel activation by 14,15-epoxyeicosatrienoic acid.
Journal: American journal of physiology. Heart and circulatory physiology 20060401
Title: IGF-I-induced VEGF expression in HUVEC involves phosphorylation and inhibition of poly(ADP-ribose)polymerase.
Journal: Biochemical and biophysical research communications 20060303
Title: MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
Journal: Diabetes 20060301
Title: Inhibition of NOS-2 induction in LPS-stimulated J774.2 cells by 1, 5-isoquinolinediol, an inhibitor of PARP.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060301
Title: The telomeric PARP, tankyrases, as targets for cancer therapy.
Journal: British journal of cancer 20060213
Title: Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure.
Journal: International journal of molecular medicine 20060201
Title: Inhibition of poly(adp-ribose) polymerase reduces cardiomyocytic apoptosis after global cardiac arrest under cardiopulmonary bypass.
Journal: Shock (Augusta, Ga.) 20060201
Title: Effect of 3-aminobenzamide on Bcl-2, Bax and AIF localization in hippocampal neurons altered by ischemia-reperfusion injury. the immunocytochemical study.
Journal: Acta neurobiologiae experimentalis 20060101
Title: Poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20060101
Title: The inhibition and treatment of breast cancer with poly (ADP-ribose) polymerase (PARP-1) inhibitors.
Journal: International journal of biological sciences 20060101
Title: Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes.
Journal: Immunity & ageing : I & A 20060101
Title: PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers?
Journal: International journal of medical sciences 20060101
Title: Poly (ADP-ribose) polymerase (PARP) is essential for sulfur mustard-induced DNA damage repair, but has no role in DNA ligase activation.
Journal: Journal of applied toxicology : JAT 20060101
Title: Inhibition of poly (ADP-ribose) polymerase as a protective effect of nicaraven in ionizing radiation- and ara-C-induced cell death.
Journal: Anticancer research 20060101
Title: A weakened transcriptional enhancer yields variegated gene expression.
Journal: PloS one 20060101
Title: Poly(ADP-ribose)polymerase activation mediates lung epithelial cell death in vitro but is not essential in hyperoxia-induced lung injury.
Journal: American journal of respiratory cell and molecular biology 20051201
Title: Inhibition of poly (ADP-ribose) synthetase improves pulmonary arterial endothelium-dependent relaxation after ischemic-reperfusion injury of splanchnic artery in rats.
Journal: Anesthesia and analgesia 20051201
Title: Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.
Journal: Diabetes 20051201
Title: Role of mitogen-activated protein kinases in hydrogen peroxide-induced cell death in osteoblastic cells.
Journal: Toxicology 20051105
Title: Biodistribution and pharmacokinetics of the (19)F-labeled radiosensitizer 3-aminobenzamide: assessment by (19)F MR imaging.
Journal: Magnetic resonance imaging 20051101
Title: Effect of 3-aminobenzamide, PARP inhibitor, on matrix metalloproteinase-9 level in plasma and brain of ischemic stroke model.
Journal: Toxicology 20051015
Title: Inhibition of poly(ADP-ribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury.
Journal: Laboratory investigation; a journal of technical methods and pathology 20051001
Title: BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency.
Journal: Cancer biology & therapy 20050901
Title: Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone.
Journal: Journal of medicinal chemistry 20050811
Title: Cigarette smoke extract induces DNA damage but not apoptosis in human bronchial epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20050801
Title: Cerebral endothelial cell apoptosis after ischemia-reperfusion: role of PARP activation and AIF translocation.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050701
Title: 3-aminobenzamide prevents restraint-evoked immunocompromise.
Journal: Brain, behavior, and immunity 20050701
Title: Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition.
Journal: Cancer biology & therapy 20050701
Title: Poly (adp-ribose) synthetase inhibition reduces oxidative and nitrosative organ damage after thermal injury.
Journal: Pediatric surgery international 20050601
Title: Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction.
Journal: Mutation research 20050502
Title: Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
Journal: The Journal of pharmacology and experimental therapeutics 20050501
Title: Inhibition of poly(ADP-ribose) polymerase attenuates lung tissue damage after hind limb ischemia-reperfusion in rats.
Journal: Pharmacological research 20050501
Title: Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin.
Journal: Cancer research 20050501
Title: Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia.
Journal: Biochemical and biophysical research communications 20050429
Title: Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat.
Journal: Brain research 20050418
Title: Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
Journal: The FEBS journal 20050401
Title: The role of poly (adenosine 5'-diphosphate-ribose) polymerase in the response of pituitary tumor cells to reactive oxygen species.
Journal: Endocrinology 20050301
Title: Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050301
Title: Regulation of alpha-synuclein expression by poly (ADP ribose) polymerase-1 (PARP-1) binding to the NACP-Rep1 polymorphic site upstream of the SNCA gene.
Journal: American journal of human genetics 20050301
Title: Mechanism of ricin-induced apoptosis in human cervical cancer cells.
Journal: Biochemical pharmacology 20050301
Title: Inhibitors of poly (ADP-ribose) polymerase ameliorate myocardial reperfusion injury by modulation of activator protein-1 and neutrophil infiltration.
Journal: Shock (Augusta, Ga.) 20050301
Title: Non A beta component of Alzheimer's disease amyloid and amyloid beta peptides evoked poly(ADP-ribose) polymerase-dependent release of apoptosis-inducing factor from rat brain mitochondria.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20050301
Title: Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
Journal: The Journal of pharmacology and experimental therapeutics 20050201
Title: Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1.
Journal: Biochemistry 20050201
Title: Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells.
Journal: FEBS letters 20050131
Title: Modulation of DNMT1 activity by ADP-ribose polymers.
Journal: Oncogene 20050106
Title: FGF2-mediated upregulation of urokinase-type plasminogen activator expression requires a MAP-kinase dependent activation of poly(ADP-ribose) polymerase.
Journal: Journal of cellular physiology 20050101
Title: Apoptosis inhibition plays a greater role than necrosis inhibition in decreasing bacterial translocation in experimental intestinal transplantation.
Journal: Surgery 20050101
Title: Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte.
Journal: Arthritis research & therapy 20050101
Title: Poly(ADP-ribosyl)ation and epigenetics. Is CTCF PARt of the plot?
Journal: Cell cycle (Georgetown, Tex.) 20050101
Title: Negative correlation between poly-ADP-ribosylation of spleen cell histone proteins and initial duration of dimethylnitrosamine exposure to mice in vivo measured by Western blot immunoprobe assay: a possible biomarker for cancer detection.
Journal: Cancer detection and prevention 20050101
Title: Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.
Journal: Respiratory research 20050101
Title: Inhibition of poly(ADP-ribose) polymerase activity protects hippocampal cells against morphological and ultrastructural alteration evoked by ischemia-reperfusion injury.
Journal: Folia neuropathologica 20050101
Title: MIBG, an inhibitor of arginine-dependent mono(ADP-ribosyl)ation, prevents differentiation of L6 skeletal myoblasts by inhibiting expression of myogenin and p21(cip1).
Journal: Experimental cell research 20041210
Title: Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs.
Journal: The Journal of pharmacology and experimental therapeutics 20041201
Title: The role of poly(ADP-ribose) synthetase inhibition on the intestinal mucosal barrier after thermal injury.
Journal: Burns : journal of the International Society for Burn Injuries 20041201
Title: 5-Aminoisoquinolinone reduces colon injury by experimental colitis.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041201
Title: Effects of poly(ADP-ribose) polymerase inhibitor on NMDA-induced retinal injury.
Journal: Current eye research 20041201
Title: Neuronal trauma model: in search of Thanatos.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20041101
Title: Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase.
Journal: Journal of medicinal chemistry 20041021
Title: Colloidal gold particles as a new in vivo marker of early acute lung injury.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041001
Title: Poly(ADP-ribose) polymerase inhibition prevents homocysteine-induced endothelial dysfunction in the isolated rat aorta.
Journal: Pharmacology 20041001
Title: Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.
Journal: Nature genetics 20041001
Title: Caspase-1 and poly (ADP-ribose) polymerase inhibitors may protect against peroxynitrite-induced neurotoxicity independent of their enzyme inhibitor activity.
Journal: The European journal of neuroscience 20041001
Title: Effects of inhibition of poly(adenosine diphosphate-ribose) synthase on acute cardiac allograft rejection.
Journal: Transplantation 20040915
Title: Inhibition of poly (ADP-ribose) polymerase and caspase-3, but not caspase-1, prevents apoptosis and improves spatial memory of rats with twice-repeated cerebral ischemia.
Journal: Life sciences 20040903
Title: A new poly(ADP-ribose) polymerase inhibitor, FR261529 [2-(4-chlorophenyl)-5-quinoxalinecarboxamide], ameliorates methamphetamine-induced dopaminergic neurotoxicity in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: The effect of PARP inhibitor on ischaemic cell death, its related inflammation and survival signals.
Journal: The European journal of neuroscience 20040901
Title: Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro.
Journal: Journal of neurotrauma 20040901
Title: Effects 3-aminobenzamide on ultrastructure of hippocampal CA1 layer after global ischemia in gerbils.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901
Title: Dual regulation of AP-2alpha transcriptional activation by poly(ADP-ribose) polymerase-1.
Journal: The Biochemical journal 20040815
Title: Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Journal: Science (New York, N.Y.) 20040813
Title: Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase.
Journal: Journal of medicinal chemistry 20040812
Title: A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.
Journal: The Journal of pharmacology and experimental therapeutics 20040801
Title: Prevention of myocardial reperfusion injury by poly(ADP-ribose) synthetase inhibitor, 3-aminobenzamide, in cardioplegic solution: in vitro study of isolated rat heart model.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040801
Title: Pharmacological inhibition of DNA repair enzymes differentially modulates telomerase activity and apoptosis in two human leukaemia cell lines.
Journal: International journal of radiation biology 20040801
Title: Role of PARP on iNOS pathway during endotoxin-induced acute lung injury.
Journal: Intensive care medicine 20040701
Title: Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.
Journal: International journal of molecular medicine 20040701
Title: Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats.
Journal: British journal of pharmacology 20040701
Title: Differential DNA double strand break fixation dependence on poly(ADP-ribosylation) in L5178Y and CHO cells.
Journal: International journal of radiation biology 20040701
Title: Long-term memory requires polyADP-ribosylation.
Journal: Science (New York, N.Y.) 20040618
Title: Effect of DNA repair inhibitor (3-aminobenzamide) on genetic stability of loach (Misgurnus fossilis) embryos derived from cryopreserved sperm.
Journal: Theriogenology 20040601
Title: Purification and properties of poly(ADP-ribose)polymerase from Crithidia fasciculata. Automodification and poly(ADP-ribosyl)ation of DNA topoisomerase I.
Journal: Molecular and biochemical parasitology 20040601
Title: TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex.
Journal: Nature genetics 20040601
Title: Dual role for poly(ADP-ribose)polymerase-1 and -2 and poly(ADP-ribose)glycohydrolase as DNA-repair and pro-apoptotic factors in rat germinal cells exposed to nitric oxide donors.
Journal: Biochimica et biophysica acta 20040528
Title: Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20040517
Title: Platelet-endothelial cell interaction in pulmonary micro-circulation: the role of PARS.
Journal: Thrombosis and haemostasis 20040401
Title: Inhibition of poly(adenosine diphosphate-ribose) polymerase decreases long-term histologic damage in testicular ischemia-reperfusion injury.
Journal: Urology 20040401
Title: Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.
Journal: Diabetes 20040301
Title: Caspase inhibition switches the mode of cell death induced by cyanide by enhancing reactive oxygen species generation and PARP-1 activation.
Journal: Toxicology and applied pharmacology 20040301
Title: Effect of poly(ADP-ribose) polymerase inhibitors on oxidative stress evoked hydroxyl radical level and macromolecules oxidation in cell free system of rat brain cortex.
Journal: Neuroscience letters 20040206
Title: PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation.
Journal: International journal of radiation oncology, biology, physics 20040201
Title: Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents.
Journal: Brain research 20040130
Title: The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).
Journal: Bioorganic & medicinal chemistry letters 20040105
Title: Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats.
Journal: Neurological research 20040101
Title: Essential role for poly (ADP-ribosyl)ation in mouse preimplantation development.
Journal: BMC molecular biology 20040101
Title: Mechanisms of suppression of neoplastic transformation in vitro by low doses of low LET radiation.
Journal: Carcinogenesis 20031201
Title: The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells.
Journal: International journal of oncology 20031201
Title: Inhibition of poly(ADP-RIBOSE) polymerase (PARP) by nitric oxide and reactive nitrogen oxide species.
Journal: Free radical biology & medicine 20031201
Title: 3-Aminobenzamide reduces brain infarction and neutrophil infiltration after transient focal cerebral ischemia in mice.
Journal: Experimental neurology 20031201
Title: Cytosolic and endoplasmic reticulum Ca2+ concentrations determine the extent and the morphological type of apoptosis, respectively.
Journal: Annals of the New York Academy of Sciences 20031201
Title: Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031119
Title: Role of poly(ADP-ribose) synthetase in pulmonary leukocyte recruitment.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031101
Title: Deleterious activation of poly(ADP-ribose)polymerase-1 in brain after in vivo oxidative stress.
Journal: Free radical research 20031101
Title: Deleterious poly(ADP-ribose)polymerase-1 pathway activation in traumatic brain injury in rat.
Journal: Brain research 20031031
Title: Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.
Journal: European journal of medical research 20031022
Title: Role of poly(ADP-ribose)polymerase in cisplatin-induced injury in LLC-PK1 cells.
Journal: Free radical biology & medicine 20031015
Title: Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion.
Journal: International journal of molecular medicine 20031001
Title: Cellular events involved in butyric acid-induced T cell apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20031001
Title: Activation of poly(adenosine diphosphate-ribose) polymerase in mouse tumors treated by photodynamic therapy.
Journal: Photochemistry and photobiology 20031001
Title: Recombinant IFN-alpha2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells.
Journal: European journal of cancer (Oxford, England : 1990) 20030901
Title: The effect of PARS inhibition on ileal histopathology, apoptosis and lipid peroxidation in LPS-induced obstructive jaundice.
Journal: Pharmacological research 20030801
Title: Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030801
Title: The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells.
Journal: Cell death and differentiation 20030801
Title: Involvement of poly(ADP-ribose) synthetase in acoustic trauma of the cochlea.
Journal: The Tohoku journal of experimental medicine 20030801
Title: Possible role of nicaraven in neuroprotective effect on hippocampal slice culture.
Journal: Canadian journal of physiology and pharmacology 20030701
Title: Hydrogen peroxide induces association between glyceraldehyde 3-phosphate dehydrogenase and phospholipase D2 to facilitate phospholipase D2 activation in PC12 cells.
Journal: Journal of neurochemistry 20030601
Title: Hsp70 attenuates hypoxia/reoxygenation-induced activation of poly(ADP-ribose) synthetase in the nucleus of adult rat cardiomyocytes.
Journal: Molecular and cellular biochemistry 20030601
Title: Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis.
Journal: European journal of pharmacology 20030523
Title: Distribution of Poly(ADP-ribosyl)ation and cell death after cerebral ischemia in the neonatal rat.
Journal: Pediatric research 20030501
Title: The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury.
Journal: The Journal of urology 20030501
Title: Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin.
Journal: The Journal of biological chemistry 20030307
Title: Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma.
Journal: American journal of respiratory cell and molecular biology 20030301
Title: Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation.
Journal: Free radical research 20030301
Title: gamma-Irradiation-induced DNA damage enhances NO production via NF-kappaB activation in RAW264.7 cells.
Journal: Biochimica et biophysica acta 20030217
Title: Impaired mitochondrial function induced by serum from septic shock patients is attenuated by inhibition of nitric oxide synthase and poly(ADP-ribose) synthase.
Journal: Critical care medicine 20030201
Title: Poly(ADP-ribose) polymerase during reperfusion after transient forebrain ischemia: its role in brain edema and cell death.
Journal: Journal of molecular neuroscience : MN 20030201
Title: Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.
Journal: Glia 20030115
Title: Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Journal: Molecular pharmacology 20030101
Title: Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis.
Journal: Molecular and cellular biochemistry 20030101
Title: Oxidant-induced cell death in renal epithelial cells: differential effects of inorganic and organic hydroperoxides.
Journal: Pharmacology & toxicology 20030101
Title: Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery.
Journal: BMC cell biology 20030101
Title: Effect of poly(ADP-ribose) polymerase inhibition on outer medullary hypoxic damage.
Journal: Nephron. Physiology 20030101
Title: Inhibition of neuronal nitric oxide synthase-mediated activation of poly(ADP-ribose) polymerase in traumatic brain injury: neuroprotection by 3-aminobenzamide.
Journal: Neuroscience 20030101
Title: Modulation of the activation of extracellular signal-regulated kinase (ERK) and the production of inflammatory mediators by ADP-ribosylation inhibitors.
Journal: Biological chemistry 20030101
Title: Oxidative stress, cell death, and other damage to alveolar epithelial cells induced by cigarette smoke.
Journal: Tobacco induced diseases 20030101
Title: Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370.
Journal: Acta crystallographica. Section D, Biological crystallography 20021201
Title: Oxidant-induced cell death in respiratory epithelial cells is due to DNA damage and loss of ATP.
Journal: Experimental lung research 20021201
Title: Role of tight junction derangement in the endothelial dysfunction elicited by exogenous and endogenous peroxynitrite and poly(ADP-ribose) synthetase.
Journal: Shock (Augusta, Ga.) 20021101
Title: The effect of H2O2 and tertiary butyl hydroperoxide upon a murine immortal lens epithelial cell line, alphaTN4-1.
Journal: Experimental eye research 20021101
Title: Enhanced recovery of radiation-induced translocations from spermatogonial stem cells of p53 null mice.
Journal: Mutation research 20021031
Title: Differential gene expression in gamma-irradiated BALB/3T3 fibroblasts under the influence of 3-aminobenzamide, an inhibitior of parp enzyme.
Journal: Mutation research 20021031
Title: Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
Journal: Glia 20021001
Title: The mechanisms of peroxynitrite-induced relaxations in isolated rat anococcygeus muscle.
Journal: Pharmacology 20020901
Title: Inhibition of poly(ADP-ribosyl)ation induces DNA hypermethylation: a possible molecular mechanism.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801
Title: The role of poly(ADP-ribose) synthetase inhibition in preventing endotoxemia-induced intestinal epithelial apoptosis.
Journal: Pharmacological research 20020801
Title: Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.
Journal: Journal of molecular and cellular cardiology 20020801
Title: Apoptosis inhibitors delay the cytopathic effect of bovine viral diarrhoea virus (BVDV).
Journal: Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20020801
Title: Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells.
Journal: Toxicology and applied pharmacology 20020715
Title: Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.
Journal: Journal of neurochemistry 20020701
Title: tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator.
Journal: Developmental cell 20020701
Title: Poly(Adp-ribose) synthetase inhibition prevents lipopolysaccharide-induced peroxynitrite mediated damage in diaphragm.
Journal: Pharmacological research 20020701
Title: The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells.
Journal: Archives of biochemistry and biophysics 20020615
Title: Liposomal NAD(+) prevents diminished O(2) consumption by immunostimulated Caco-2 cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Roles of oxidative stress and glutathione depletion in JP-8 jet fuel-induced apoptosis in rat lung epithelial cells.
Journal: Toxicology and applied pharmacology 20020415
Title: Modulation of pyridyl cyanoguanidine (CHS 828) induced cytotoxicity by 3-aminobenzamide in U-937 GTB cells.
Journal: Biochemical pharmacology 20020415
Title: DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability.
Journal: Journal of cell science 20020401
Title: Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition.
Journal: The Journal of biological chemistry 20020322
Title: Protective effects of poly (ADP-ribose) synthase inhibitors on digoxin-induced cardiotoxicity in guinea-pig isolated hearts.
Journal: Pharmacological research 20020301
Title: Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.
Journal: Cancer chemotherapy and pharmacology 20020301
Title: [Modification of repair DNA synthesis in mutagen-treated human fibroblasts during adaptive response and the antimutagenic effect of garlic extract].
Journal: Genetika 20020301
Title: [Comparison of the protective effect of garlic extract and cell defense during adaptive response].
Journal: Genetika 20020301
Title: Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside.
Journal: Cell death and differentiation 20020201
Title: X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance.
Journal: Cancer research 20020115
Title: Sensitivity of HaCat keratinocytes to diabetogenic toxins.
Journal: Biochemical pharmacology 20020115
Title: Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
Journal: Carcinogenesis 20020101
Title: Meningitis-associated central nervous system complications are mediated by the activation of poly(ADP-ribose) polymerase.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020101
Title: Bench-to-bedside review: Cytopathic hypoxia.
Journal: Critical care (London, England) 20020101
Title: Development of a high-throughput screening-amenable assay for human poly(ADP-ribose) polymerase inhibitors.
Journal: Journal of pharmacological and toxicological methods 20020101
Title: Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes.
Journal: Free radical biology & medicine 20011215
Title: The sequence-specific DNA binding of NF-kappa B is reversibly regulated by the automodification reaction of poly (ADP-ribose) polymerase 1.
Journal: The Journal of biological chemistry 20011214
Title: Impairment of the neuronal dopamine transporter activity in MPP(+)-treated rat was not prevented by treatments with nitric oxide synthase or poly(ADP-ribose) polymerase inhibitors.
Journal: Neuroscience letters 20011113
Title: Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis.
Journal: The Journal of biological chemistry 20011012
Title: Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment.
Journal: Brain research 20011012
Title: Proteasomal degradation of oxidatively damaged endogenous histones in K562 human leukemic cells.
Journal: Free radical biology & medicine 20011001
Title: Different effects of tert-butylhydroperoxide-induced peroxynitrite-dependent and -independent DNA single-strand breakage on PC12 cell poly(ADP-ribose) polymerase activity.
Journal: European journal of biochemistry 20011001
Title: TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.
Journal: The Journal of biological chemistry 20010921
Title: Activation of poly(ADP-ribose) polymerase in severe hemorrhagic shock and resuscitation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20010801
Title: Histone H3 phosphorylation is coupled to poly-(ADP-ribosylation) during reactive oxygen species-induced cell death in renal proximal tubular epithelial cells.
Journal: Molecular pharmacology 20010801
Title: Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences.
Journal: British journal of pharmacology 20010801
Title: Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture?
Journal: Shock (Augusta, Ga.) 20010801
Title: Poly(adp-ribose) synthetase inhibition reduces bacterial translocation in rats after endotoxin challenge.
Journal: Shock (Augusta, Ga.) 20010801
Title: Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection.
Journal: Cell death and differentiation 20010801
Title: Cell density-dependent death mode switch of cultured cortical neurons under serum-free starvation stress.
Journal: Cellular and molecular neurobiology 20010801
Title: Role of zinc in pulmonary endothelial cell response to oxidative stress.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010701
Title: Characterization of poly(ADP-ribose)polymerase from Crithidia fasciculata: enzyme inhibition by beta-lapachone.
Journal: Molecular and biochemical parasitology 20010701
Title: Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity.
Journal: The Journal of investigative dermatology 20010701
Title: Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system.
Journal: Molecular pharmacology 20010601
Title: 3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet.
Journal: Neurological research 20010601
Title: Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Journal: Molecular medicine (Cambridge, Mass.) 20010601
Title: Regulation of the nuclear proteasome activity in myelomonocytic human leukemia cells after adriamycin treatment.
Journal: Blood 20010501
Title: Suppression of the radiation-sensitive phenotype of hamster irs1 and irs2 strains selected for resistance to 3-aminobenzamide.
Journal: International journal of radiation biology 20010501
Title: Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.
Journal: Cancer chemotherapy and pharmacology 20010401
Title: H2O2-induced cell death in human glioma cells: role of lipid peroxidation and PARP activation.
Journal: Neurochemical research 20010401
Title: A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression.
Journal: The Journal of biological chemistry 20010323
Title: Role of cell cycle control in radiosensitization of mouse spermatogonial stem cells.
Journal: International journal of radiation biology 20010301
Title: Rat germinal cells require PARP for repair of DNA damage induced by gamma-irradiation and H2O2 treatment.
Journal: European journal of cell biology 20010301
Title: Poly(adenosine diphosphate-ribose) synthetase inhibitor 3-aminobenzamide alleviates cochlear dysfunction induced by transient ischemia.
Journal: The Annals of otology, rhinology, and laryngology 20010201
Title: Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid.
Journal: Molecular pharmacology 20010101
Title: Regulation of bleomycin-induced DNA breakage and chromatin structure in lung endothelial cells by integrins and poly(ADP-ribose) polymerase.
Journal: Molecular pharmacology 20010101
Title: Inhibition of poly(ADP-ribose) polymerase attenuates cerebral vasospasm after subarachnoid hemorrhage in rabbits.
Journal: Stroke 20010101
Title: The role of nitric oxide in diaphragmatic dysfunction in endotoxemic rats.
Journal: Muscle & nerve 20010101
Title: Excessive base excision repair of 5-hydroxymethyluracil from DNA induces apoptosis in Chinese hamster V79 cells containing mutant p53.
Journal: Carcinogenesis 20010101
Title: Cigarette smoke and asbestos activate poly-ADP-ribose polymerase in alveolar epithelial cells.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20010101
Title: [Neuronal death: potential role of the nuclear enzyme, poly (ADP-ribose) polymerase].
Journal: Bulletin de l'Academie nationale de medecine 20010101
Title: Poly(ADP-ribose) polymerase-1 regulates the stability of the wild-type p53 protein.
Journal: Cellular & molecular biology letters 20010101
Title: Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20001101
Title: All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor.
Journal: Leukemia research 20000401
Title: N-methyl-D-aspartate (NMDA)--induced apoptosis in rat retina.
Journal: Investigative ophthalmology & visual science 19990901
Title: Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
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