Home Other Building Blocks 38647-11-9
38647-11-9,MFCD00210566
Catalog No.:AA00I7LC

38647-11-9 | Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione,3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-,(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$89.00   $62.00
- +
5mg
≥98%
in stock  
$338.00   $237.00
- +
10mg
in stock  
$450.00   $315.00
- +
25mg
≥98%
in stock  
$1,107.00   $775.00
- +
50mg
≥98%
in stock  
$1,699.00   $1,189.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I7LC
Chemical Name:
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione,3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-,(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-
CAS Number:
38647-11-9
Molecular Formula:
C20H22O6
Molecular Weight:
358.3851
MDL Number:
MFCD00210566
SMILES:
O=C1OCC2=C1CC[C@]1([C@H]2C[C@H]2[C@@]3([C@@]41O[C@H]4[C@@H]1O[C@@]1(C3=O)C(C)C)O2)C
NSC Number:
165677
Properties
Computed Properties
 
Complexity:
860  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
1  
XLogP3:
0.7  

Literature

Title: Triptonide acts as a novel potent anti-lymphoma agent with low toxicity mainly through inhibition of proto-oncogene Lyn transcription and suppression of Lyn signal pathway.

Journal: Toxicology letters 20170815

Title: Semisynthesis of triptolide analogues: effect of γ-lactone and C-14 substituents on cytotoxic activities.

Journal: Bioorganic & medicinal chemistry letters 20110515

Title: XPB, a subunit of TFIIH, is a target of the natural product triptolide.

Journal: Nature chemical biology 20110301

Title: Synthesis and biological evaluation of novel triptolide analogues for anticancer activity.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Fluorination of triptolide and its analogues and their cytotoxicity.

Journal: Bioorganic & medicinal chemistry letters 20080401

Title: Determination of triptonide by cloud point extraction combined with MEKC.

Journal: Journal of separation science 20080301

Title: Immunochemical characterization of the functional constituents of Tripterygium wilfordii contributing to its anti-inflammatory property.

Journal: Clinical and experimental pharmacology & physiology 20080101

Title: Simultaneous determination of triptolide, wilforlide A and triptonide in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Biological & pharmaceutical bulletin 20060701

Title: Semisynthesis of C-ring modified triptolide analogues and their cytotoxic activities.

Journal: Bioorganic & medicinal chemistry letters 20060401

Title: Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography.

Journal: Biomedical chromatography : BMC 20050101

Title: Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus.

Journal: Journal of Asian natural products research 20040601

Title: [Effects of chlorotriptolide and triptonide on chromosome aberration and micronuclei of bone marrow cell in male rats].

Journal: Zhonghua nan ke xue = National journal of andrology 20021201

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:38647-11-9 Molecular Formula|38647-11-9 MDL|38647-11-9 SMILES|38647-11-9 Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione,3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-,(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-