[1]JournalofHeterocyclicChemistry,1988,vol.25,p.1899-1903
[2]BiochemicalPharmacology,1995,vol.50,p.163-168
[1]Tetrahedron,1984,vol.40,p.125-135
[1]HelveticaChimicaActa,1993,vol.76,p.158-167
[1]JournalofHeterocyclicChemistry,1988,vol.25,p.1899-1903
[1]PharmaceuticalChemistryJournal,1985,vol.19,p.259-261 Khimiko-FarmatsevticheskiiZhurnal,1985,vol.19,p.425-427
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