Title: Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats.
Journal: Hepatology (Baltimore, Md.) 20121101
Title: The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease.
Journal: Neurobiology of aging 20120801
Title: Dopamine dysregulation syndrome including mania related to coadministration of droxidopa.
Journal: Journal of clinical psychopharmacology 20120601
Title: Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline.
Journal: The Tohoku journal of experimental medicine 20120101
Title: Optimal production of L-threo-2,3-dihydroxyphenylserine (L-threo-DOPS) on a large scale by diastereoselectivity-enhanced variant of L-threonine aldolase expressed in Escherichia coli.
Journal: Preparative biochemistry & biotechnology 20120101
Title: Effects of carbidopa and entacapone on the metabolic fate of the norepinephrine prodrug L-DOPS.
Journal: Journal of clinical pharmacology 20110101
Title: Identification of clinically used drugs that activate pregnane X receptors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: DBH deficiency in an elderly patient: efficacy and safety of chronic droxidopa.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20100601
Title: Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505
Title: Contamination of the norepinephrine prodrug droxidopa by dihydroxyphenylacetaldehyde.
Journal: Clinical chemistry 20100501
Title: [New perspectives on molecular and genic therapies in Down syndrome].
Journal: Medecine sciences : M/S 20100401
Title: [Pharmacological hypotheses and therapeutic strategies for gait disorders in Parkinson's disease].
Journal: Revue neurologique 20100201
Title: Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Title: Diastereoselective synthesis of L: -threo-3,4-dihydroxyphenylserine by low-specific L: -threonine aldolase mutants.
Journal: Biotechnology letters 20100101
Title: Enhanced synthesis of L-threo-3,4-dihydroxyphenylserine by high-density whole-cell biocatalyst of recombinant L-threonine aldolase from Streptomyces avelmitilis.
Journal: Biotechnology letters 20090301
Title: Neurogenic orthostatic hypotension: new prospects in treatment. Introduction.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20080301
Title: L-dihydroxyphenylserine (Droxidopa): a new therapy for neurogenic orthostatic hypotension: the US experience.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20080301
Title: L-dihydroxyphenylserine (Droxidopa) in the treatment of orthostatic hypotension: the European experience.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20080301
Title: Comment on 'Midodrine hydrochloride and L-threo-3,4-dihydroxy-phenylserine preserve cerebral blood flow in hemodialysis patients with orthostatic hypotension' by Fujisaki et al.
Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20071001
Title: Synthesis of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) with thermostabilized low-specific L-threonine aldolase from Streptomyces coelicolor A3(2).
Journal: Journal of microbiology and biotechnology 20070501
Title: Midodrine hydrochloride and L-threo-3,4-dihydroxy-phenylserine preserve cerebral blood flow in hemodialysis patients with orthostatic hypotension.
Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20070201
Title: Noradrenaline is necessary for the hedonic properties of addictive drugs.
Journal: Vascular pharmacology 20061001
Title: Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward.
Journal: Science (New York, N.Y.) 20060217
Title: The discovery of the pressor effect of DOPS and its blunting by decarboxylase inhibitors.
Journal: Journal of neural transmission. Supplementum 20060101
Title: L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug.
Journal: Cardiovascular drug reviews 20060101
Title: Case report: Marathon runner with severe autonomic failure.
Journal: Lancet (London, England) 20051201
Title: L-DOPS therapy for refractory orthostatic hypotension in autoimmune autonomic neuropathy.
Journal: Neurology 20051011
Title: [Pure akinesia presenting with antecollis].
Journal: No to shinkei = Brain and nerve 20051001
Title: L-threo 3,4-dihydroxyphenylserine treatment during mouse perinatal and rat postnatal development does not alter the impact of dietary copper deficiency.
Journal: Nutritional neuroscience 20050601
Title: [Simple method for precognition of drug interaction between oral iron and phenolic hydroxyl group-containing drugs].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050201
Title: An explanation of the unexpected efficacy of L-DOPS in pure autonomic failure.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20041201
Title: Clinical pharmacokinetics of the norepinephrine precursor L-threo-DOPS in primary chronic autonomic failure.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20041201
Title: Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20040525
Title: Norepinephrine precursor therapy in neurogenic orthostatic hypotension.
Journal: Circulation 20030812
Title: [Human striatal D-neurons and their significance].
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20020801
Title: Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase.
Journal: Biochemical and biophysical research communications 20020705
Title: Clinical effects of L-threo-3,4-dihydroxyphenylserine on orthostatic hypotension in hemodialysis patients.
Journal: Nephron 20020401
Title: Efficacy of high sodium intake in a boy with instantaneous orthostatic hypotension.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20020201
Title: Effects of L-threo-3,4-dihydroxyphenylserine on orthostatic hypotension in hemodialysis patients.
Journal: American journal of nephrology 20020101
Title: The norepinephrine precursor L-threo-3,4-dihydroxyphenylserine facilitates motor recovery in chronic stroke patients.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20011101
Title: L-threo-dihydroxyphenylserine (L-threo-DOPS; droxidopa) in the management of neurogenic orthostatic hypotension: a multi-national, multi-center, dose-ranging study in multiple system atrophy and pure autonomic failure.
Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20010801
Title: Synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-(3,4-dihydroxyphenyl)serine as potential in vivo precursors of fluorinated norepinephrines.
Journal: The Journal of organic chemistry 20010713
Title: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Journal: The Journal of biological chemistry 20010518
Title: Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine.
Journal: Clinical neuropharmacology 20010101
Title: Effect of midodrine on chlorpromazine-induced orthostatic hypotension in rabbits: comparison with amezinium, etilefrine and droxidopa.
Journal: Biological & pharmaceutical bulletin 20001201
Title: [Malignant syndrome in multiple system atrophy].
Journal: No to shinkei = Brain and nerve 19970601
Title: The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Journal: Experientia 19931015
Title: Attenuation of haloperidol-induced catalepsy by noradrenaline and L-threo-DOPS.
Journal: Journal of neural transmission. Parkinson's disease and dementia section 19930101
Title: Effect of L-threo-3,4-dihydroxyphenylserine on muscle sympathetic nerve activity in humans.
Journal: Journal of the autonomic nervous system 19920615
Title: Oxaprotiline enantiomers given repeatedly and brain alpha-adrenoceptors.
Journal: Journal of neural transmission. General section 19900101
Title: L-threo-3,4-dihydroxyphenylserine treatment for gait apraxia in parkinsonian patients.
Journal: The Kurume medical journal 19890101
Title: Effect of L-threo-3,4-dihydroxyphenylserine on muscle sympathetic nerve activities in Shy-Drager syndrome.
Journal: Neurology 19880701
Title: Alteration of lidocaine- or procaine-induced convulsions by manipulation of brain amines.
Journal: Journal of dental research 19810201
Title: [Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19760401
