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39236-46-9,MFCD00221482
Catalog No.:AA003D6I

39236-46-9 | Imidurea

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10g
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$7.00   $5.00
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25g
98%
in stock  
$16.00   $11.00
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100g
98%
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$32.00   $22.00
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500g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003D6I
Chemical Name:
Imidurea
CAS Number:
39236-46-9
Molecular Formula:
C11H16N8O8
Molecular Weight:
388.2935
MDL Number:
MFCD00221482
SMILES:
OCN1C(=O)NC(=O)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO
Properties
Properties
 
Form:
Liquid  
MP:
>215°C (subl.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
627  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
2  
XLogP3:
-3.4  

Literature

Title: Acidic conditions induce the suppression of CD86 and CD54 expression in THP-1 cells.

Journal: The Journal of toxicological sciences 20180101

Title: An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401

Title: Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.

Journal: Toxicology and applied pharmacology 20150301

Title: Differentiation of skin sensitizers from irritant chemicals by interleukin-1α and macrophage inflammatory protein-2 in murine keratinocytes.

Journal: Toxicology letters 20130110

Title: Characterization of the decomposition of compounds derived from imidazolidinyl urea in cosmetics and patch test materials.

Journal: Contact dermatitis 20121101

Title: Cell chip-based monitoring of toxic effects of cosmetic compounds on skin fibroblast cells.

Journal: Journal of nanoscience and nanotechnology 20120701

Title: B cell increases and ex vivo IL-2 production as secondary endpoints for the detection of sensitizers in non-radioisotopic local lymph node assay using flow cytometry.

Journal: Toxicology letters 20120325

Title: Formalehyde in personal care products.

Journal: Skin pharmacology and physiology 20120101

Title: Simultaneous determination of eleven preservatives in cosmetics by micellar electrokinetic chromatography.

Journal: Journal of AOAC International 20120101

Title: Hydrogel allergic contact dermatitis and imidazolidinyl urea/diazolidinyl urea.

Journal: Cutaneous and ocular toxicology 20111201

Title: Patch testing with formaldehyde and formaldehyde-releasers: multicentre study in Spain (2005-2009).

Journal: Contact dermatitis 20111101

Title: Non-fragrance allergens in specific cosmetic products.

Journal: Contact dermatitis 20111101

Title: The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: results of a ring-study in five laboratories.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110401

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100901

Title: Allergic contact dermatitis in a girl due to several cosmetics containing diazolidinyl-urea or imidazolidinyl-urea.

Journal: Contact dermatitis 20100701

Title: Positive concomitant test reactions to allergens in the standard patch test series.

Journal: International journal of dermatology 20100501

Title: Formaldehyde-releasers in cosmetics in the USA and in Europe.

Journal: Contact dermatitis 20100401

Title: Temporal trends of preservative allergy in Denmark (1985-2008).

Journal: Contact dermatitis 20100201

Title: Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 1. Characterization, frequency and relevance of sensitization, and frequency of use in cosmetics.

Journal: Contact dermatitis 20100101

Title: Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 2. Patch test relationship to formaldehyde contact allergy, experimental provocation tests, amount of formaldehyde released, and assessment of risk to consumers allergic to formaldehyde.

Journal: Contact dermatitis 20100101

Title: Hand dermatitis: a focus on allergic contact dermatitis to biocides.

Journal: Dermatologic clinics 20090701

Title: Sensitivity of petrolatum and aqueous vehicles for detecting allergy to imidazolidinylurea, diazolidinylurea, and DMDM hydantoin: a retrospective analysis from the North American Contact Dermatitis Group.

Journal: Dermatitis : contact, atopic, occupational, drug 20070901

Title: The relationship of vehicle and concentration for imidazolidinylurea, with attention to formaldehyde allergy status.

Journal: Dermatitis : contact, atopic, occupational, drug 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The relationship of vehicle and concentration of imidazolidinylurea, with attention to formaldehyde allergy status.

Journal: Dermatitis : contact, atopic, occupational, drug 20060301

Title: Can an imidazolidinyl urea-preserved corticosteroid cream be safely used in individuals hypersensitive to formaldehyde?

Journal: Contact dermatitis 20060101

Title: Characterization and chemistry of imidazolidinyl urea and diazolidinyl urea.

Journal: Contact dermatitis 20060101

Title: Cosmetic dermatitis in Chinese eczema patients patch tested with a modified European standard series of allergens.

Journal: Contact dermatitis 20051201

Title: [Allergy to diazolidinyl urea (Germall II) and imidazolidinyl urea (Germall 115)].

Journal: Annales de dermatologie et de venereologie 20050101

Title: [Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20040501

Title: In vitro induction of apoptosis vs. necrosis by widely used preservatives: 2-phenoxyethanol, a mixture of isothiazolinones, imidazolidinyl urea and 1,2-pentanediol.

Journal: Biochemical pharmacology 20020201

Title: Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 1. Synthesis and pharmacological activity of chain derivatives of 1-aryl-2-iminoimidazolidine containing urea moiety.

Journal: European journal of medicinal chemistry 20011001

Title: Standardization of the TRUE Test imidazolidinyl urea and diazolidinyl urea patches.

Journal: Contact dermatitis 20010701

Title: Comparison of patch test results with a standard series among white and black racial groups.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010601

Title: Developing a dynamic pharmacophore model for HIV-1 integrase.

Journal: Journal of medicinal chemistry 20000601

Title: Doi T, et al. Characterization of the decomposition of compounds derived from imidazolidinyl urea in cosmetics and patch test materials. Contact Dermatitis. 2012 Nov;67(5):284-92.

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