Home Amines 3963-62-0
3963-62-0,MFCD00008143
Catalog No.:AA0032UA

3963-62-0 | 2,2-Diphenylethylamine

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1g
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$7.00   $5.00
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5g
96%
in stock  
$26.00   $18.00
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10g
96%
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$46.00   $32.00
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25g
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$92.00   $64.00
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100g
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$234.00   $164.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0032UA
Chemical Name:
2,2-Diphenylethylamine
CAS Number:
3963-62-0
Molecular Formula:
C14H15N
Molecular Weight:
197.2756
MDL Number:
MFCD00008143
SMILES:
NCC(c1ccccc1)c1ccccc1
NSC Number:
27209
Properties
Properties
 
BP:
314.7°C at 760 mmHg  
Form:
Solid  
MP:
43-49 °C  
Refractive Index:
1.5616 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
148  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.1  

Downstream Synthesis Route
108-97-4    3963-62-0   
1-(2,2-diphenyl-ethyl)-1<i>H</i>-pyridin-4-one 

[1]JournaloftheAmericanChemicalSociety,1947,vol.69,p.858

[1]Cha,JinSoon;Brown,HerbertC.[JournalofOrganicChemistry,1993,vol.58,#15,p.3974-3979]

[2]Murugesan,Kathiravan;Senthamarai,Thirusangumurugan;Sohail,Manzar;Alshammari,AhmadS.;Pohl,Marga-Martina;Beller,Matthias;Jagadeesh,RajenahallyV.[ChemicalScience,2018,vol.9,#45,p.8553-8560]

[3]Huisgen;Ruechardt[JustusLiebigsAnnalenderChemie,1956,vol.601,p.21,31]

[4]Benoitetal.[AnnalesPharmaceutiquesFrancaises,1952,vol.10,p.181,186]

[5]Kotschhetkow;Petrutschenko[ZhurnalObshcheiKhimii,1958,vol.28,p.2252,2254,2255;engl.Ausg.S.2288.2289,2290]

[6]Rupe;Gisiger[HelveticaChimicaActa,1925,vol.8,p.349]

[7]Decombe[ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1946,vol.222,p.90]

[8]Freeman;Ringk;Spoerri[JournaloftheAmericanChemicalSociety,1947,vol.69,p.858]

[9]Nystrom[JournaloftheAmericanChemicalSociety,1955,vol.77,p.2544]

[10]Eiden;Iwan[ArchivderPharmazieundBerichtederDeutschenPharmazeutischenGesellschaft,1970,vol.303,#7,p.612-617]

[11]Rajsner,M.etal.[CollectionofCzechoslovakChemicalCommunications,1963,vol.28,p.1031-1043]

[12]Brown,HerbertC.;Choi,YongMoon;Narasimhan,S.[Synthesis,1981,#8,p.605-606]

[13]Wakamatsu,Takeshi;Inaki,Harumi;Ogawa,Akemi;Watanabe,Masako;Ban,Yoshio[Heterocycles,1980,vol.14,#10,p.1437-1440]

[14]Zamani,Asghar;PoursattarMarjani,Ahmad;Nikoo,Abbas;Heidarpour,Mojtaba;Dehghan,Ahmad[InorganicandNano-MetalChemistry,2018,vol.48,#3,p.176-181]

[15]Mészáros,Rebeka;Peng,Bai-Jing;Ötvös,SándorB.;Yang,Shyh-Chyun;Fülöp,Ferenc[ChemPlusChem,2019,vol.84,#10,p.1508-1511]

[1]Nagubandi,Sreeramulu;Fodor,G.[JournalofHeterocyclicChemistry,1980,vol.17,p.1457-1463]

[2]Kurouchi,Hiroaki[ChemicalCommunications,2020,vol.56,#59,p.8313-8316]

[3]Otsuka,Rikuto;Maruhashi,Kazuo;Ohwada,Tomohiko[Synthesis,2018,vol.50,#10,p.2041-2057]

[4]Rupe;Gisiger[HelveticaChimicaActa,1925,vol.8,p.349]

[5]Levy;Gallais[BulletindelaSocieteChimiquedeFrance,1928,vol.&lt;4&gt;43,p.865]

[6]Nagubandi,Sreeramulu[OrganicMassSpectrometry,1980,vol.15,#10,p.535-538]

[1]Journalofmedicinalchemistry,1989,vol.32,p.1667-1673

[2]JournalofMedicinalChemistry,2000,vol.43,p.4135-4150

[3]Patent:US4582823,1986,A

[4]Patent:US4657897,1987,A

[1]JournalofMedicinalChemistry,1991,vol.34,p.2877-2882

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity.

Journal: Bioorganic & medicinal chemistry 20090915

Title: NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds.

Journal: Bioorganic & medicinal chemistry 20090501

Title: Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigation.

Journal: Journal of medicinal chemistry 20081113

Title: Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Two- and three-dimensional quantitative structure-activity relationships studies on a series of liver x receptor ligands.

Journal: The open medicinal chemistry journal 20080101

Title: Quantification of cibenzoline by enzyme-linked immunosorbent assay.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070601

Title: Geometry-affinity relationships of the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.

Journal: Journal of medicinal chemistry 20020411

Title: Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin receptor.

Journal: Bioorganic & medicinal chemistry letters 20010226

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