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421581-70-6,MFCD03142768
Catalog No.:AA00C0VM

421581-70-6 | 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole

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1g
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$29.00   $20.00
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5g
97%
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$54.00   $38.00
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25g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00C0VM
Chemical Name:
5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
CAS Number:
421581-70-6
Molecular Formula:
C14H8FN3O3
Molecular Weight:
285.2300
MDL Number:
MFCD03142768
SMILES:
Fc1ccc(cc1)c1onc(n1)c1cccc(c1)[N+](=O)[O-]
Properties
Computed Properties
 
Complexity:
371  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
2  
XLogP3:
3.4  

Downstream Synthesis Route

[1]Kandre,Shivaji;Bhagat,PundlikRambhau;Sharma,Rajiv;Gupte,Amol[TetrahedronLetters,2013,vol.54,#27,p.3526-3529]

Literature

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Title: Design and synthesis of Selenazole-containing peptides for cocrystallization with P-glycoprotein.

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Journal: Mycopathologia 20110401

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Title: Commercial mouthwashes are more effective than azole antifungals against Candida albicans biofilms in vitro.

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Title: Structure of Ralstonia eutropha flavohemoglobin in complex with three antibiotic azole compounds.

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Journal: Frontiers in bioscience (Scholar edition) 20110101

Title: Antimicrobial topical agents used in the vagina.

Journal: Current problems in dermatology 20110101

Title: Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata.

Journal: PloS one 20110101

Title: Epidemiology and antifungal resistance in invasive Aspergillosis according to primary disease: review of the literature.

Journal: European journal of medical research 20110101

Title: Effects of prevention of oxidative and nitro-oxidative stress on experimental rat colon anastomosis using acetylcysteine, Ebselen and 1400w.

Journal: Acta chirurgica Belgica 20110101

Title: In vivo activity of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida species.

Journal: BMC complementary and alternative medicine 20110101

Title: Beneficial effects of N-acetylcysteine and ebselen on renal ischemia/reperfusion injury.

Journal: Renal failure 20110101

Title: Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide.

Journal: Neurologia medico-chirurgica 20110101

Title: Synthesis of modified steroids as a novel class of non-ulcerogenic, anti-inflammatory and anti-nociceptive agents.

Journal: Steroids 20110101

Title: Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

Journal: PloS one 20110101

Title: Comparative drug susceptibility study of five clonal strains of Trichomonas vaginalis in vitro.

Journal: Asian Pacific journal of tropical medicine 20110101

Title: [Therapeutic efficacy of Triazavirin, a novel Russian chemotherapeutic, against influenza virus A (H5N1)].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20110101

Title: Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51).

Journal: Advances in parasitology 20110101

Title: Novel diphenylamine 2,4'-dicarboxamide based azoles as potential epidermal growth factor receptor inhibitors: synthesis and biological activity.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: [Influence of rimantadine, ribavirine and triazavirine on influenza A virus replication in human monolayer and lymphoblastoid cell lines].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties.

Journal: Organic & biomolecular chemistry 20101221

Title: Chain length effect on the binding of amphiphiles to serum albumin and to POPC bilayers.

Journal: The journal of physical chemistry. B 20101216

Title: Green synthesis and biological evaluation of some novel azoles as antimicrobial agents.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Cu-catalyzed efficient synthetic methodology for ebselen and related Se-N heterocycles.

Journal: Organic letters 20101203

Title: Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse.

Journal: Diabetes 20101201

Title: Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.

Journal: The Journal of antimicrobial chemotherapy 20101201

Title: Proteomic analysis of cytosolic proteins associated with petite mutations in Candida glabrata.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20101201

Title: Antifungal prophylaxis and therapy in patients with hematological malignancies and hematopoietic stem cell transplant recipients.

Journal: Expert review of anti-infective therapy 20101201

Title: Azole drugs trap cytochrome P450 EryK in alternative conformational states.

Journal: Biochemistry 20101102

Title: Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.

Journal: Antimicrobial agents and chemotherapy 20101101

Title: Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain.

Journal: Antimicrobial agents and chemotherapy 20101101

Title: A rapid and efficient route to benzazole heterocycles.

Journal: Nature protocols 20101101

Title: Pharmacological considerations for azole antifungal drug management in cystic fibrosis lung transplant patients.

Journal: Medical mycology 20101101

Title: Synthesis and in vitro anticancer activities of some selenadiazole derivatives.

Journal: Archiv der Pharmazie 20101101

Title: Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.

Journal: Antimicrobial agents and chemotherapy 20101001

Title: In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan.

Journal: International journal of antimicrobial agents 20101001

Title: Azole derivatives as histamine H3 receptor antagonists, part 2: C-C and C-S coupled heterocycles.

Journal: Bioorganic & medicinal chemistry letters 20101001

Title: Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: azoles: effective metal chelators.

Journal: Bioorganic & medicinal chemistry letters 20101001

Title: Azole derivatives as histamine H3 receptor antagonists, part I: thiazol-2-yl ethers.

Journal: Bioorganic & medicinal chemistry letters 20101001

Title: Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Cutaneous phaeohyphomycosis in renal allograft recipients: report of 2 cases and review of the literature.

Journal: Diagnostic microbiology and infectious disease 20101001

Title: Dynamics within site selectively templated and tagged xerogel sensor platforms.

Journal: Applied spectroscopy 20101001

Title: Cobalt-catalyzed addition of azoles to alkynes.

Journal: Organic letters 20100917

Title: Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives.

Journal: ChemMedChem 20100903

Title: Interactions between antifungal and antiretroviral agents.

Journal: Expert opinion on drug safety 20100901

Title: Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100901

Title: Experimental murine scedosporiosis: histopathology and azole treatment.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents.

Journal: European journal of medicinal chemistry 20100901

Title: The serine/threonine protein phosphatase Sit4p activates multidrug resistance in Saccharomyces cerevisiae.

Journal: FEMS yeast research 20100901

Title: Functional characterization of the PP2C phosphatase CaPtc2p in the human fungal pathogen Candida albicans.

Journal: Yeast (Chichester, England) 20100901

Title: Reversal of stereoselectivity in the Cu-catalyzed conjugate addition reaction of dialkylzinc to cyclic enone in the presence of a chiral azolium compound.

Journal: The Journal of organic chemistry 20100820

Title: Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis.

Journal: FEMS yeast research 20100801

Title: Azole antimycotics and drug interactions in the perioperative period.

Journal: Current opinion in anaesthesiology 20100801

Title: Management of drug and food interactions with azole antifungal agents in transplant recipients.

Journal: Pharmacotherapy 20100801

Title: An enantioselective Claisen rearrangement catalyzed by N-heterocyclic carbenes.

Journal: Journal of the American Chemical Society 20100707

Title: The antifungal properties of chicken egg cystatin against Candida yeast isolates showing different levels of azole resistance.

Journal: Mycoses 20100701

Title: Impact of education and an antifungal stewardship program for candidiasis at a Thai tertiary care center.

Journal: Infection control and hospital epidemiology 20100701

Title: [Advances in the study of Candida albicans gene mutation on azole drug resistance].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100701

Title: Diphenyl diselenide behaves differently than ebselen under different pH media in rat's liver preparations.

Journal: Pathology, research and practice 20100615

Title: Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601

Title: Microbiological characteristics of clinical isolates of Cryptococcus neoformans in Taiwan: serotypes, mating types, molecular types, virulence factors, and antifungal susceptibility.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601

Title: Phaeohyphomycosis due to Alternaria species in transplant recipients.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100601

Title: Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia.

Journal: American journal of physiology. Heart and circulatory physiology 20100601

Title: New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site.

Journal: Bioorganic & medicinal chemistry 20100601

Title: Synthesis of a second generation chroman/catechol hybrids and evaluation of their activity in protecting neuronal cells from oxidative stress-induced cell death.

Journal: Bioorganic & medicinal chemistry 20100601

Title: In vitro synergistic interactions of the effects of various statins and azoles against some clinically important fungi.

Journal: FEMS microbiology letters 20100601

Title: Metal-free coupling of azoles with 2- and 3-haloindoles providing access to novel 2- or 3-(azol-1-yl)indole derivatives.

Journal: Organic letters 20100521

Title: Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazole.

Journal: ChemMedChem 20100503

Title: Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100501

Title: Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: [Therapy of candidemia and invasive candidiasis according to guidelines].

Journal: Mycoses 20100501

Title: [Guideline based treatment of invasive aspergillosis].

Journal: Mycoses 20100501

Title: Antifungal drug resistance: not all azoles are equal.

Journal: Expert review of anti-infective therapy 20100501

Title: Solid phase extraction--multisyringe flow injection system for the spectrophotometric determination of selenium with 2,3-diaminonaphthalene.

Journal: Talanta 20100415

Title: In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species.

Journal: Mycopathologia 20100401

Title: Exogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes.

Journal: Cardiovascular research 20100401

Title: Molecular aspects of azoles-induced teratogenesis.

Journal: Expert opinion on drug metabolism & toxicology 20100401

Title: Susceptibility to five antifungals of Aspergillus fumigatus strains isolated from chronically colonised cystic fibrosis patients receiving azole therapy.

Journal: International journal of antimicrobial agents 20100401

Title: Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes.

Journal: PLoS pathogens 20100401

Title: Ebselen reduces inflammation and microvascular perfusion failure after blunt skeletal muscle injury of the rat.

Journal: The Journal of trauma 20100401

Title: Invasive candidiasis in the intensive care unit.

Journal: Hospital practice (1995) 20100401

Title: Cloud point extraction and electrothermal atomic absorption spectrometry of Se (IV)--3,3'-diaminobenzidine for the estimation of trace amounts of Se (IV) and Se (VI) in environmental water samples and total selenium in animal blood and fish tissue samples.

Journal: Journal of hazardous materials 20100315

Title: Current concepts in systemic and topical therapy for superficial mycoses.

Journal: Clinics in dermatology 20100304

Title: Urban pigeons (Columba livia) as a potential source of pathogenic yeasts: a focus on antifungal susceptibility of Cryptococcus strains in Northeast Brazil.

Journal: Mycopathologia 20100301

Title: Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors.

Journal: Journal of inorganic biochemistry 20100301

Title: Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.

Journal: ChemMedChem 20100301

Title: Prophylactic antifungal agents used after lung transplantation.

Journal: The Annals of pharmacotherapy 20100301

Title: 5-Selenization of salicylic acid derivatives yielded isoform-specific 5-lipoxygenase inhibitors.

Journal: Organic & biomolecular chemistry 20100221

Title: Determination of Se(IV) in natural waters by adsorptive stripping voltammetry of 5-nitropiazselenol.

Journal: Journal of hazardous materials 20100215

Title: Copper-catalyzed annulation of 2-formylazoles with o-aminoiodoarenes.

Journal: The Journal of organic chemistry 20100205

Title: Metabolic control of antifungal drug resistance.

Journal: Fungal genetics and biology : FG & B 20100201

Title: Inhibition of Candida albicans growth by brominated furanones.

Journal: Applied microbiology and biotechnology 20100201

Title: Photoinactivation of Candida albicans by its own endogenous porphyrins.

Journal: Current microbiology 20100201

Title: PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans.

Journal: Microbiology (Reading, England) 20100201

Title: Treatment of endemic mycoses.

Journal: Expert review of respiratory medicine 20100201

Title: The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues.

Journal: Biochemistry 20100126

Title: Opposing regulation of histamine-induced calcium signaling by sodium selenite and ebselen via alterations of thiol redox status.

Journal: European journal of pharmacology 20100125

Title: Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.

Journal: Bioorganic & medicinal chemistry 20100115

Title: NBD-based green fluorescent ligands for typing of thymine-related SNPs by using an abasic site-containing probe DNA.

Journal: Chembiochem : a European journal of chemical biology 20100104

Title: Treatment outcome of invasive mould disease after sequential exposure to azoles and liposomal amphotericin B.

Journal: The Journal of antimicrobial chemotherapy 20100101

Title: A new naphthimidazole derivative for saccharide labeling with enhanced sensitivity in mass spectrometry detection.

Journal: Rapid communications in mass spectrometry : RCM 20100101

Title: Synergistic mechanisms of retigeric acid B and azoles against Candida albicans.

Journal: Journal of applied microbiology 20100101

Title: In vitro activities of azole antifungal agents against Propionibacterium acnes isolated from patients with acne vulgaris.

Journal: Biological & pharmaceutical bulletin 20100101

Title: [Update: invasive fungal infections: Diagnosis and treatment in surgical intensive care medicine].

Journal: Der Anaesthesist 20100101

Title: Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis.

Journal: Bioscience, biotechnology, and biochemistry 20100101

Title: Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

Journal: PloS one 20100101

Title: Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family.

Journal: BMC biology 20100101

Title: Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen.

Journal: PloS one 20100101

Title: Development of specific inhibitors of CYP707A, a key enzyme in the catabolism of abscisic acid.

Journal: Current medicinal chemistry 20100101

Title: Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance.

Journal: PloS one 20100101

Title: Beyond ergosterol: linking pH to antifungal mechanisms.

Journal: Virulence 20100101

Title: [Triazavirin prophylactic efficacy against influenza virus A (H5N1)].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101

Title: Solution versus fluorous versus solid-phase synthesis of 2,5-disubstituted 1,3-azoles. Preliminary antibacterial activity studies.

Journal: The Journal of organic chemistry 20091204

Title: Comparative mechanisms of zearalenone and ochratoxin A toxicities on cultured HepG2 cells: is oxidative stress a common process?

Journal: Environmental toxicology 20091201

Title: The current role of amphotericin B lipid complex in managing systemic fungal infections.

Journal: Current medical research and opinion 20091201

Title: Azole-resistance in Aspergillus: proposed nomenclature and breakpoints.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20091201

Title: 2-Amino-nonyl-6-methoxyl-tetralin muriate inhibits sterol C-14 reductase in the ergosterol biosynthetic pathway.

Journal: Acta pharmacologica Sinica 20091201

Title: Inhibitory mechanism of novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae.

Journal: Journal of microbiology and biotechnology 20091201

Title: Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

Journal: Chemical communications (Cambridge, England) 20091114

Title: Towards the mechanism and comparative effect of diphenyl diselenide, diphenyl ditelluride and ebselen under various pathophysiological conditions in rat's kidney preparation.

Journal: Chemico-biological interactions 20091110

Title: Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs.

Journal: Molecular microbiology 20091101

Title: Neuroprotection of ebselen against ischemia/reperfusion injury involves GABA shunt enzymes.

Journal: Journal of the neurological sciences 20091015

Title: Discovery of highly potent novel antifungal azoles by structure-based rational design.

Journal: Bioorganic & medicinal chemistry letters 20091015

Title: New azoles with potent antifungal activity: design, synthesis and molecular docking.

Journal: European journal of medicinal chemistry 20091001

Title: Atypical Aspergillus flavus isolates associated with chronic azole therapy.

Journal: Journal of clinical microbiology 20091001

Title: Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD.

Journal: American journal of physiology. Heart and circulatory physiology 20091001

Title: Practical catalytic asymmetric synthesis of diaryl-, aryl heteroaryl-, and diheteroarylmethanols.

Journal: Journal of the American Chemical Society 20090902

Title: 3-imidazolyl-substituted flavans as potential antifungal agents: synthesis, stereochemical properties, and antifungal activity.

Journal: Archiv der Pharmazie 20090901

Title: New generation azole antifungals in clinical investigation.

Journal: Expert opinion on investigational drugs 20090901

Title: Structure-based and in silico design of Hsp90 inhibitors.

Journal: ChemMedChem 20090901

Title: A general copper-catalyzed coupling of azoles with vinyl bromides.

Journal: The Journal of organic chemistry 20090821

Title: In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.

Journal: Antimicrobial agents and chemotherapy 20090801

Title: HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury.

Journal: The Journal of surgical research 20090801

Title: Role of Ndt80p in sterol metabolism regulation and azole resistance in Candida albicans.

Journal: Eukaryotic cell 20090801

Title: Hsp90 orchestrates stress response signaling governing fungal drug resistance.

Journal: PLoS pathogens 20090801

Title: The optimal wavelength of spectrophotometric broth microdilution antifungal susceptibility test for flucytosine and three azoles.

Journal: The Korean journal of laboratory medicine 20090801

Title: Seleniranium ion-triggered reactions: new aspects of Friedel-Crafts and N-detosylative cyclizations.

Journal: Organic letters 20090702

Title: Discrete generations of intracellular hydrogen peroxide and superoxide in antigen-stimulated mast cells: reciprocal regulation of store-operated Ca2+ channel activity.

Journal: Molecular immunology 20090701

Title: Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure.

Journal: Emerging infectious diseases 20090701

Title: Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.

Journal: PLoS pathogens 20090701

Title: Practical synthesis of a potent bradykinin B(1) antagonist via enantioselective hydrogenation of a pyridyl N-acyl enamide.

Journal: The Journal of organic chemistry 20090619

Title: Hollow fiber liquid phase microextraction followed by high performance liquid chromatography for determination of ultra-trace levels of Se(IV) after derivatization in urine, plasma and natural water samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090615

Title: Mutations in the CgPDR1 and CgERG11 genes in azole-resistant Candida glabrata clinical isolates from Slovakia.

Journal: International journal of antimicrobial agents 20090601

Title: Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090601

Title: Ibuprofen reverts antifungal resistance on Candida albicans showing overexpression of CDR genes.

Journal: FEMS yeast research 20090601

Title: Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20090601

Title: Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.

Journal: FEMS microbiology letters 20090601

Title: [Antifungals for systemic use].

Journal: Enfermedades infecciosas y microbiologia clinica 20090601

Title: Antagonists of the P2X(7) receptor. From lead identification to drug development.

Journal: Journal of medicinal chemistry 20090528

Title: Taguchi OA16 orthogonal array design for the optimization of cloud point extraction for selenium determination in environmental and biological samples by tungsten-modified tube electrothermal atomic absorption spectrometry.

Journal: Talanta 20090515

Title: Clinical relevance of the pharmacokinetic interactions of azole antifungal drugs with other coadministered agents.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090515

Title: Modeling the oxidation of ebselen and other organoselenium compounds using explicit solvent networks.

Journal: The journal of physical chemistry. A 20090514

Title: Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells.

Journal: Hearing research 20090501

Title: Antifungal drug resistance mechanisms.

Journal: Expert review of anti-infective therapy 20090501

Title: Azole-resistant central nervous system aspergillosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090415

Title: Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20090415

Title: Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.

Journal: Free radical biology & medicine 20090415

Title: In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance.

Journal: Antimicrobial agents and chemotherapy 20090401

Title: Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation.

Journal: Archives of dermatological research 20090401

Title: [Species-specific differences in Rhodamine 6G accumulation of Candida isolates detected by flow cytometric analysis].

Journal: The Korean journal of laboratory medicine 20090401

Title: Ghrelin receptor modulators and their therapeutic potential.

Journal: Future medicinal chemistry 20090401

Title: The redox state of glutathione regulates the hypoxic induction of HIF-1.

Journal: European journal of pharmacology 20090315

Title: Enhancement of iron-catalyzed lipid peroxidation by acidosis in brain homogenate: comparative effect of diphenyl diselenide and ebselen.

Journal: Brain research 20090303

Title: Susceptibility of Candida albicans to common and novel antifungal drugs, and relationship between the mating type locus and resistance, in Lebanese hospital isolates.

Journal: Mycoses 20090301

Title: Oral candidiasis of HIV-infected children undergoing sequential HIV therapies.

Journal: Medical mycology 20090301

Title: Candida spp. in vitro susceptibility profile to four antifungal agents. Resistance surveillance study in Venezuelan strains.

Journal: Medical mycology 20090301

Title: Susceptibility testing of Cryptococcus diffluens against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole and posaconazole.

Journal: Medical mycology 20090301

Title: Redox modulation at the peripheral site alters nociceptive transmission in vivo.

Journal: Clinical and experimental pharmacology & physiology 20090301

Title: Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery.

Journal: Medical mycology 20090301

Title: Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301

Title: Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists.

Journal: Bioorganic & medicinal chemistry letters 20090301

Title: Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20090301

Title: Functional analysis of the Kluyveromyces lactis PDR1 gene.

Journal: FEMS yeast research 20090301

Title: Design of an assembly of poly(benzimidazole), carbon nanotubes, and Pt nanoparticles for a fuel-cell electrocatalyst with an ideal interfacial nanostructure.

Journal: Small (Weinheim an der Bergstrasse, Germany) 20090301

Title: New antifungal agents in pediatric practice.

Journal: Indian pediatrics 20090301

Title: Aqueous solvent system for the solubilization of azole compounds.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215

Title: Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugates.

Journal: Bioorganic & medicinal chemistry 20090215

Title: Synthesis, antitubercular activity and docking study of novel cyclic azole substituted diphenyl ether derivatives.

Journal: European journal of medicinal chemistry 20090201

Title: Pre-treatment with ebselen and vitamin E modulate acetylcholinesterase activity: interaction with demyelinating agents.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090201

Title: Adoptive transfer of syngeneic bone marrow-derived cells in mice with obesity-induced diabetes: selenoorganic antioxidant ebselen restores stem cell competence.

Journal: The American journal of pathology 20090201

Title: Amyloidophilic compounds for prion diseases.

Journal: Infectious disorders drug targets 20090201

Title: Clinical indications for newer antifungal agents.

Journal: Journal of hospital medicine 20090201

Title: Fungal nail infections: diagnosis and management.

Journal: Prescrire international 20090201

Title: Threshold to N-methyl-D-aspartate-induced seizures in mice undergoing chronic nutritional magnesium deprivation is lowered in a way partly responsive to acute magnesium and antioxidant administrations.

Journal: The British journal of nutrition 20090201

Title: Antagonists of the human A(2A) adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo[4,5-d]pyrimidines.

Journal: Journal of medicinal chemistry 20090108

Title: Synthesis of telluroamino acid derivatives with remarkable GPx like activity.

Journal: Organic & biomolecular chemistry 20090107

Title: Antidepressant-like effect of the organoselenium compound ebselen in mice: evidence for the involvement of the monoaminergic system.

Journal: European journal of pharmacology 20090105

Title: Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials.

Journal: European journal of medicinal chemistry 20090101

Title: Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system.

Journal: Tuberculosis (Edinburgh, Scotland) 20090101

Title: RTA2 is involved in calcineurin-mediated azole resistance and sphingoid long-chain base release in Candida albicans.

Journal: Cellular and molecular life sciences : CMLS 20090101

Title: International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations.

Journal: Antimicrobial agents and chemotherapy 20090101

Title: Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

Title: Ebselen improves ischemia-reperfusion injury after rat lung transplantation.

Journal: Lung 20090101

Title: Determination of azole antifungal medicines using zero-order and derivative UV spectrophotometry.

Journal: Acta poloniae pharmaceutica 20090101

Title: [Determination of 12 azole fungicide residues in beans and corn by offline disperse solid phase extraction and gas chromatography-negative chemical ionization mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20090101

Title: Antifungal treatment for invasive Candida infections: a mixed treatment comparison meta-analysis.

Journal: Annals of clinical microbiology and antimicrobials 20090101

Title: Molecular differentiation and antifungal susceptibility of Candida albicans isolated from patients with respiratory infections in Guiyang Medical College Hospital, China.

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101

Title: Detection and antifungal susceptibility testing of oral Candida dubliniensis from human immunodeficiency virus-infected patients.

Journal: Indian journal of pathology & microbiology 20090101

Title: Effects of N-acetylcysteine and ebselen on arachidonic acid release from astrocytes and neurons cultured in normoxic or simulated ischemic conditions.

Journal: Pharmacological reports : PR 20090101

Title: [Azole-resistant invasive aspergillosis].

Journal: Nederlands tijdschrift voor geneeskunde 20090101

Title: How do azoles inhibit cytochrome P450 enzymes? A density functional study.

Journal: The journal of physical chemistry. A 20081218

Title: CYP51: A major drug target in the cytochrome P450 superfamily.

Journal: Lipids 20081201

Title: Covalent bonding of azoles to quaternary protoberberine alkaloids.

Journal: Magnetic resonance in chemistry : MRC 20081201

Title: [What's new in the molecular basis of antifungal drug resistance in pathogenic yeasts].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20081201

Title: [Cryptococcosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20081201

Title: [Potential of anidulafungin in hematological patients].

Journal: Enfermedades infecciosas y microbiologia clinica 20081201

Title: [Potential of anidulafungin in combined therapy].

Journal: Enfermedades infecciosas y microbiologia clinica 20081201

Title: Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.

Journal: The Journal of biological chemistry 20081128

Title: Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1).

Journal: Journal of medicinal chemistry 20081113

Title: 1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.

Journal: European journal of medicinal chemistry 20081101

Title: Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding.

Journal: Clinical pharmacology and therapeutics 20081101

Title: A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.

Journal: PLoS pathogens 20081101

Title: Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism.

Journal: PLoS medicine 20081101

Title: Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice.

Journal: Free radical research 20081101

Title: Activity of amphotericin B, anidulafungin, caspofungin, micafungin, posaconazole, and voriconazole against Candida albicans with decreased susceptibility to fluconazole from APECED patients on long-term azole treatment of chronic mucocutaneous candidiasis.

Journal: Diagnostic microbiology and infectious disease 20081001

Title: Subculture on potato dextrose agar as a complement to the broth microdilution assay for Malassezia pachydermatis.

Journal: Journal of microbiological methods 20081001

Title: Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae.

Journal: Fungal genetics and biology : FG & B 20081001

Title: Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion.

Journal: Journal of neurochemistry 20081001

Title: Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.

Journal: Antimicrobial agents and chemotherapy 20081001

Title: Azole fungicides: occurrence and fate in wastewater and surface waters.

Journal: Environmental science & technology 20081001

Title: The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth.

Journal: Virology 20080930

Title: Synthesis and antiviral activity of azoles obtained from carbohydrates.

Journal: Carbohydrate research 20080922

Title: RTA2, a novel gene involved in azole resistance in Candida albicans.

Journal: Biochemical and biophysical research communications 20080905

Title: Persistent pulmonary infection with an azole-resistant Coccidioides species.

Journal: Medical mycology 20080901

Title: A case of endocarditis caused by the yeast Pichia fabianii with biofilm production and developed in vitro resistance to azoles in the course of antifungal treatment.

Journal: Medical mycology 20080901

Title: Lipolytic and esterolytic activity-based profiling of murine liver.

Journal: Proteomics 20080901

Title: Candida albicans UPC2 is transcriptionally induced in response to antifungal drugs and anaerobicity through Upc2p-dependent and -independent mechanisms.

Journal: Microbiology (Reading, England) 20080901

Title: The structure of alkali metal derivatives of azoles: N-sigma versus pi structures.

Journal: The journal of physical chemistry. A 20080821

Title: Determination of physiological thiols by electrochemical detection with piazselenole and its application in rat breast cancer cells 4T-1.

Journal: Journal of the American Chemical Society 20080820

Title: Synthesis, structure, spectroscopic properties, and antiproliferative activity in vitro of novel osmium(III) complexes with azole heterocycles.

Journal: Inorganic chemistry 20080818

Title: Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid.

Journal: The Journal of organic chemistry 20080815

Title: Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase.

Journal: Journal of medicinal chemistry 20080814

Title: Micafungin activity against Candida albicans with diverse azole resistance phenotypes.

Journal: The Journal of antimicrobial chemotherapy 20080801

Title: Multilocus sequence typing confirms synonymy but highlights differences between Candida albicans and Candida stellatoidea.

Journal: FEMS yeast research 20080801

Title: Primary antifungal prophylaxis in hematopoietic stem cell transplant recipients: clinical implications of recent studies.

Journal: Current opinion in infectious diseases 20080801

Title: Hydrolysis and cytotoxic properties of osmium(II)/(III)-DMSO-azole complexes. Short communication.

Journal: Chemistry & biodiversity 20080801

Title: Copper complexes of anionic nitrogen ligands in the amidation and imidation of aryl halides.

Journal: Journal of the American Chemical Society 20080730

Title: Selenium compounds counteract the stimulation of ecto-nucleotidase activities in rat cultured cerebellar granule cells: putative correlation with neuroprotective effects.

Journal: Brain research 20080724

Title: Optimization of azoles as anti-human immunodeficiency virus agents guided by free-energy calculations.

Journal: Journal of the American Chemical Society 20080723

Title: Immunocompromised hosts: immunopharmacology of modern antifungals.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080715

Title: Synthesis, potent anti-staphylococcal activity and QSARs of some novel 2-anilinobenzazoles.

Journal: European journal of medicinal chemistry 20080701

Title: A phase 2, open-label study of the safety and efficacy of intravenous anidulafungin as a treatment for azole-refractory mucosal candidiasis.

Journal: Journal of acquired immune deficiency syndromes (1999) 20080701

Title: Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.

Journal: Bioorganic & medicinal chemistry 20080615

Title: Design, synthesis, characterization, antibacterial and antifungal activities of a novel class of 5,7-diaryl-4,4-dimethyl-4,5,6,7-tetrahydropyridino[3,4-d]-1,2,3-selenadiazoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20080601

Title: Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat.

Journal: Neuroscience 20080502

Title: Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501

Title: Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.

Journal: Eukaryotic cell 20080501

Title: Characterization of caspofungin susceptibilities by broth and agar in Candida albicans clinical isolates with characterized mechanisms of azole resistance.

Journal: Medical mycology 20080501

Title: New options for treatment of candidaemia in critically ill patients.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501

Title: Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae.

Journal: Microbiology (Reading, England) 20080501

Title: Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein.

Journal: The Journal of biological chemistry 20080418

Title: Overanticoagulation with coumarin and cutaneous azole therapy.

Journal: Annals of internal medicine 20080415

Title: Ebselen attenuates cadmium-induced testicular damage in mice.

Journal: Journal of applied toxicology : JAT 20080401

Title: Endocrine-disrupting properties in vivo of widely used azole fungicides.

Journal: International journal of andrology 20080401

Title: An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae).

Journal: Phytochemistry 20080401

Title: The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata.

Journal: Molecular microbiology 20080401

Title: Synergistic activity of azoles with amiodarone against clinically resistant Candida albicans tested by chequerboard and time-kill methods.

Journal: Journal of medical microbiology 20080401

Title: Characterization of type II ligands in CYP2C9 and CYP3A4.

Journal: Journal of medicinal chemistry 20080327

Title: Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs.

Journal: European journal of pharmacology 20080317

Title: Mechanistic studies of a palladium-catalyzed intramolecular hydroamination of unactivated alkenes: protonolysis of a stable palladium alkyl complex is the turnover-limiting step.

Journal: Journal of the American Chemical Society 20080305

Title: In vitro interaction between azoles and cyclosporin A against clinical isolates of Candida albicans determined by the chequerboard method and time-kill curves.

Journal: The Journal of antimicrobial chemotherapy 20080301

Title: Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells.

Journal: Mutagenesis 20080301

Title: Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes.

Journal: Toxicology 20080227

Title: Rh(I)-catalyzed arylation of heterocycles via C-H bond activation: expanded scope through mechanistic insight.

Journal: Journal of the American Chemical Society 20080227

Title: Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.

Journal: Journal of neuroscience research 20080215

Title: Aryl azoles with neuroprotective activity--parallel synthesis and attempts at target identification.

Journal: Bioorganic & medicinal chemistry 20080215

Title: Effect of substituents on the GPx-like activity of ebselen: steric versus electronic.

Journal: The journal of physical chemistry. A 20080207

Title: Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study.

Journal: Biochimica et biophysica acta 20080201

Title: Azole antifungals induce up-regulation of SAP4, SAP5 and SAP6 secreted proteinase genes in filamentous Candida albicans cells in vitro and in vivo.

Journal: The Journal of antimicrobial chemotherapy 20080201

Title: Intermolecular hydroaminations via strained (E)-cycloalkenes.

Journal: The Journal of organic chemistry 20080201

Title: Total synthesis of thiopeptide antibiotics GE2270A, GE2270T, and GE2270C1.

Journal: Chemistry, an Asian journal 20080201

Title: Synthesis and anticandidal activity of azole-containing sulfonamides.

Journal: Archiv der Pharmazie 20080201

Title: [Successful treatment of azole-refractory Candida guilliermondii fungemia with a combination therapy of micafungin and liposomal amphotericin B].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20080201

Title: Antifungal serum concentration monitoring: an update.

Journal: The Journal of antimicrobial chemotherapy 20080101

Title: In vitro interactions between azoles and amiodarone against clinical Candida albicans.

Journal: International journal of antimicrobial agents 20080101

Title: 2-Hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: 'Click' dendrimers: synthesis, redox sensing of Pd(OAc)2, and remarkable catalytic hydrogenation activity of precise Pd nanoparticles stabilized by 1,2,3-triazole-containing dendrimers.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Antifungal drugs.

Journal: Treatment guidelines from the Medical Letter 20080101

Title: Toward basic understanding of the partition coefficient log P and its application in QSAR.

Journal: SAR and QSAR in environmental research 20080101

Title: In search of the holy grail of antifungal therapy.

Journal: Transactions of the American Clinical and Climatological Association 20080101

Title: Antioxidant activity of the anti-inflammatory compound ebselen: a reversible cyclization pathway via selenenic and seleninic acid intermediates.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Alpha-lipoic acid and ebselen prevent ischemia/reperfusion injury in the rat intestine.

Journal: Surgery today 20080101

Title: Synthesis, characterization and antimicrobial activity of new 1,2,3-selenadiazoles.

Journal: Molecules (Basel, Switzerland) 20080101

Title: Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells.

Journal: Cutaneous and ocular toxicology 20080101

Title: Molecular properties relevant to bioavailability of tioconazole and its derivatives.

Journal: Acta poloniae pharmaceutica 20080101

Title: Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20071215

Title: Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.

Journal: The Journal of biological chemistry 20071214

Title: The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum.

Journal: The Journal of antimicrobial chemotherapy 20071201

Title: cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p.

Journal: Eukaryotic cell 20071201

Title: [Chronic ethanol feeding induces oxidative stress in the rat retina: treatment with the antioxidant ebselen].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20071201

Title: Ebselen attenuates oxidative DNA damage and enhances its repair activity in the thalamus after focal cortical infarction in hypertensive rats.

Journal: Brain research 20071121

Title: Oxidative addition of 2-substituted azolium salts to Group-10 metal zero complexes--a DFT study.

Journal: Dalton transactions (Cambridge, England : 2003) 20071107

Title: Antifungal activity of statins against Aspergillus species.

Journal: Medical mycology 20071101

Title: Species distribution and susceptibility to azole antifungals of Candida bloodstream isolates from eight university hospitals in Korea.

Journal: Yonsei medical journal 20071031

Title: Copper(I)-catalyzed highly efficient synthesis of benzoselenazoles and benzotellurazoles.

Journal: The Journal of organic chemistry 20071012

Title: (45)Ca(2+) influx in rat brain: effect of diorganylchalcogenides compounds.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071001

Title: Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats.

Journal: American journal of physiology. Heart and circulatory physiology 20071001

Title: Improved outcomes associated with advances in therapy for invasive fungal infections in immunocompromised hosts.

Journal: The Journal of infection 20071001

Title: Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients.

Journal: The Journal of antimicrobial chemotherapy 20071001

Title: Carbon monoxide stimulates the Ca2(+)-activated big conductance k channels in cultured human endothelial cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20071001

Title: 3,3'-diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis.

Journal: Chemical research in toxicology 20071001

Title: Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(alpha-azolylbenzyl)-1H-indoles as selective aromatase inhibitors.

Journal: Journal of enzyme inhibition and medicinal chemistry 20071001

Title: Dynamics of membrane protein/amphipol association studied by Förster resonance energy transfer: implications for in vitro studies of amphipol-stabilized membrane proteins.

Journal: Biochemistry 20070911

Title: Azole therapy of clinical and experimental coccidioidomycosis.

Journal: Annals of the New York Academy of Sciences 20070901

Title: Chemotherapeutic evaluation of alginate nanoparticle-encapsulated azole antifungal and antitubercular drugs against murine tuberculosis.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20070901

Title: The diverse chemistry of oxazol-5-(4H)-ones.

Journal: Chemical Society reviews 20070901

Title: Surface modification of cetyltrimethylammonium bromide-capped gold nanorods to make molecular probes.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070814

Title: Synthesis and evaluation of novel 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[(4-substitutedphenyl)-piperazin-1-yl]-propan-2-ols as antifungal agents.

Journal: European journal of medicinal chemistry 20070801

Title: Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.

Journal: Research in veterinary science 20070801

Title: Treatment of acute Old World cutaneous leishmaniasis: a systematic review of the randomized controlled trials.

Journal: Journal of the American Academy of Dermatology 20070801

Title: Enantioselective separation of azole compounds by EKC. Reversal of migration order of enantiomers with CD concentration.

Journal: Electrophoresis 20070801

Title: Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae.

Journal: Eukaryotic cell 20070701

Title: Identification of Y118 amino acid residue in Candida albicans sterol 14alpha-demethylase associated with the enzyme activity and selective antifungal activity of azole analogues.

Journal: Biological & pharmaceutical bulletin 20070701

Title: Previous treatment with ebselen and vitamin E alters adenine nucleotide hydrolysis in platelets from adult rats experimentally demyelinated with ethidium bromide.

Journal: Life sciences 20070627

Title: Diverse functionalization of thiazolo ring-fused 2-pyridones.

Journal: The Journal of organic chemistry 20070622

Title: Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP).

Journal: Bioorganic & medicinal chemistry letters 20070615

Title: Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070601

Title: Synthesis of azole nucleoside analogues of D-pinitol as potential antitumor agents.

Journal: Carbohydrate research 20070507

Title: Monitoring the looping up of acyl chain labeled NBD lipids in membranes as a function of membrane phase state.

Journal: Biochimica et biophysica acta 20070501

Title: Deficient peroxide detoxification underlies the susceptibility of oligodendrocyte progenitors to dopamine toxicity.

Journal: Neuropharmacology 20070501

Title: Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans.

Journal: Molecular microbiology 20070501

Title: Transmembrane transport of peptidoglycan precursors across model and bacterial membranes.

Journal: Molecular microbiology 20070501

Title: Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity.

Journal: Toxicology and industrial health 20070501

Title: Density functional theory study of the reaction mechanism and energetics of the reduction of hydrogen peroxide by ebselen, ebselen diselenide, and ebselen selenol.

Journal: The journal of physical chemistry. A 20070426

Title: Ebselen treatment reduces noise induced hearing loss via the mimicry and induction of glutathione peroxidase.

Journal: Hearing research 20070401

Title: Role of endogenous hydrogen peroxide in the development of nitrate tolerance.

Journal: Vascular pharmacology 20070401

Title: Antifungal susceptibility of 1000 Candida bloodstream isolates to 5 antifungal drugs: results of a multicenter study conducted in São Paulo, Brazil, 1995-2003.

Journal: Diagnostic microbiology and infectious disease 20070401

Title: Synthesis and antibacterial activity of some 5-(4-biphenylyl)-7-aryl [3,4-d]-1,2,3-benzoselenadiazoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20070401

Title: Enantiomeric separation of several antimycotic azole drugs using supercritical fluid chromatography.

Journal: Journal of chromatography. A 20070316

Title: Location and dynamics of acyl chain NBD-labeled phosphatidylcholine (NBD-PC) in DPPC bilayers. A molecular dynamics and time-resolved fluorescence anisotropy study.

Journal: Biochimica et biophysica acta 20070301

Title: ortho-Substituted azoles as selective and dual inhibitors of VEGF receptors 1 and 2.

Journal: Bioorganic & medicinal chemistry letters 20070301

Title: Spontaneous, intervesicular transfer rates of fluorescent, acyl chain-labeled phosphatidylcholine analogs.

Journal: Biochimica et biophysica acta 20070301

Title: Differential reactivity of alpha and beta 2'-deoxyribonucleosides towards protonation and metalation.

Journal: Journal of inorganic biochemistry 20070301

Title: Antifungal activities of azole agents against the Malassezia species.

Journal: International journal of antimicrobial agents 20070301

Title: Ebselen prevents chronic alcohol-induced rat hippocampal stress and functional impairment.

Journal: Alcoholism, clinical and experimental research 20070301

Title: [Mechanisms of resistance to antifungal agents].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20070227

Title: N-Acetylcysteine and ebselen but not nifedipine protected cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.

Journal: Neuroscience research 20070201

Title: Synthesis, characterization, and antioxidant activity of some ebselen analogues.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Antifungal drug susceptibility of Cryptococcus neoformans from clinical sources in Nairobi, Kenya.

Journal: Mycoses 20070101

Title: Voriconazole resistant Candida spp. and Saccharomyces spp. isolates from oropharyngeal candidiasis from Cambodian children with AIDS not pretreated with azoles (letter).

Journal: Scandinavian journal of infectious diseases 20070101

Title: [The role of sterols in morphogenetic processes and dimorphism in fungi].

Journal: Mikrobiologiia 20070101

Title: Fluorescent fructose derivatives for imaging breast cancer cells.

Journal: Bioconjugate chemistry 20070101

Title: Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents.

Journal: European journal of medicinal chemistry 20070101

Title: Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection.

Journal: HIV clinical trials 20070101

Title: Synthesis of novel N-rich polycyclic skeletons based on azoles and pyridines.

Journal: Journal of combinatorial chemistry 20070101

Title: A method for determination of selenium in organic tissues using microwave digestion and liquid chromatography.

Journal: Journal of AOAC International 20070101

Title: Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents.

Journal: Current medicinal chemistry 20070101

Title: New noninvasive methodology for real-time monitoring of lipid flip.

Journal: Bioconjugate chemistry 20070101

Title: [Treatment of fungal infections of upper respiratory tract and ear].

Journal: Otolaryngologia polska = The Polish otolaryngology 20070101

Title: Evaluation of the antimicrobial activity of ebselen: role of the yeast plasma membrane H+-ATPase.

Journal: Journal of biochemical and molecular toxicology 20070101

Title: Effects of ebselen on glutathione level in neurons exposed to arachidonic acid and 4-hydroxynonenal during simulated ischemia in vitro.

Journal: Pharmacological reports : PR 20070101

Title: Species distribution and susceptibility to azoles of vaginal yeasts isolated prostitutes.

Journal: Infectious diseases in obstetrics and gynecology 20070101

Title: [Investigation of triazavirin antiviral activity against influenza A virus (H5N1) in cell culture].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101

Title: Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode.

Journal: The Journal of biological chemistry 20061222

Title: CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.

Journal: Biochemical Society transactions 20061201

Title: Factors influencing the magnitude and clinical significance of drug interactions between azole antifungals and select immunosuppressants.

Journal: Pharmacotherapy 20061201

Title: Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats.

Journal: Basic & clinical pharmacology & toxicology 20061201

Title: Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.

Journal: Toxicology 20061110

Title: Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.

Journal: Chemico-biological interactions 20061107

Title: Ebselen effects on MPTP-induced neurotoxicity.

Journal: Brain research 20061106

Title: In vitro activity and synergism of amphotericin B, azoles and cationic antimicrobials against the emerging pathogen Trichoderma spp.

Journal: The Journal of antimicrobial chemotherapy 20061101

Title: Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20061101

Title: Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.

Journal: Bioorganic & medicinal chemistry letters 20061015

Title: Inexpensive, one-pot synthesis of unsymmetrical disulfides using 1-chlorobenzotriazole.

Journal: The Journal of organic chemistry 20061013

Title: Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2.

Journal: Molecular microbiology 20061001

Title: Oxidative stress induces ADAM9 protein expression in human prostate cancer cells.

Journal: Cancer research 20061001

Title: Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061001

Title: Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20060901

Title: Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in rats.

Journal: Basic & clinical pharmacology & toxicology 20060901

Title: Ebselen, a seleno-organic antioxidant, as an electrophile.

Journal: Chemical research in toxicology 20060901

Title: Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake.

Journal: Chemistry & biology 20060901

Title: Effect of selenium compounds on the damage induced by oxysterol on rat arterial walls.

Journal: Biological trace element research 20060901

Title: Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils.

Journal: European journal of pharmacology 20060814

Title: Cloning and characterization of CYP51 from Mycobacterium avium.

Journal: American journal of respiratory cell and molecular biology 20060801

Title: Proteomic analysis of experimentally induced azole resistance in Candida glabrata.

Journal: The Journal of antimicrobial chemotherapy 20060801

Title: Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing efflux pump genes.

Journal: The Journal of antimicrobial chemotherapy 20060801

Title: Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies.

Journal: Molecular microbiology 20060801

Title: Treatment options of invasive fungal infections in adults.

Journal: Swiss medical weekly 20060722

Title: Aneuploidy and isochromosome formation in drug-resistant Candida albicans.

Journal: Science (New York, N.Y.) 20060721

Title: Modeling the reduction of hydrogen peroxide by glutathione peroxidase mimics.

Journal: The journal of physical chemistry. A 20060720

Title: Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen.

Journal: Brain : a journal of neurology 20060701

Title: Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701

Title: Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense.

Journal: Journal of natural products 20060701

Title: A new non-azole inhibitor of ABA 8'-hydroxylase: effect of the hydroxyl group substituted for geminal methyl groups in the six-membered ring.

Journal: Bioorganic & medicinal chemistry letters 20060615

Title: Direct assay for alpha-amylase using fluorophore-modified cyclodextrins.

Journal: Bioorganic & medicinal chemistry 20060601

Title: Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20060601

Title: In vitro antifungal susceptibility to six antifungal agents of 229 Candida isolates from patients with diabetes mellitus.

Journal: Oral microbiology and immunology 20060601

Title: Design of clinical trials of empiric antifungal therapy in patients with persistent febrile neutropenia: considerations and critiques.

Journal: Pharmacotherapy 20060601

Title: Treatment options for invasive fungal infections.

Journal: Pharmacotherapy 20060601

Title: Emerging antifungal azoles and effects on Magnaporthe grisea.

Journal: Mycological research 20060601

Title: PDR16-mediated azole resistance in Candida albicans.

Journal: Molecular microbiology 20060601

Title: Measuring translocation of fluorescent lipid derivatives across yeast Golgi membranes.

Journal: Methods (San Diego, Calif.) 20060601

Title: Antileishmanial activities and mechanisms of action of indole-based azoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20060601

Title: Synthesis and antifungal activity of new thienyl and aryl conazoles.

Journal: Journal of enzyme inhibition and medicinal chemistry 20060601

Title: Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics.

Journal: Organic letters 20060525

Title: Neuroprotective effects of ebselen are associated with the regulation of Bcl-2 and Bax proteins in cultured mouse cortical neurons.

Journal: Neuroscience letters 20060522

Title: Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron.

Journal: Biochimie 20060501

Title: Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes.

Journal: European journal of medicinal chemistry 20060501

Title: Diphenyl ditelluride- and methylmercury-induced hyperphosphorilation of the high molecular weight neurofilament subunit is prevented by organoselenium compounds in cerebral cortex of young rats.

Journal: Toxicology 20060501

Title: Ebselen induced C6 glioma cell death in oxygen and glucose deprivation.

Journal: Chemical research in toxicology 20060501

Title: Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.

Journal: Journal of medicinal chemistry 20060420

Title: Drug interactions during therapy with three major groups of antimicrobial agents.

Journal: Expert opinion on pharmacotherapy 20060401

Title: Pharmaceutical prescribing for children. Part 4. Antifungal and antiviral therapy.

Journal: Primary dental care : journal of the Faculty of General Dental Practitioners (UK) 20060401

Title: Effect of azoles on the secretion of a Candida albicans metallopeptidase.

Journal: Mycopathologia 20060301

Title: Protective effect of ebselen on cytotoxicity induced by cholestane-3 beta, 5 alpha, 6 beta-triol in ECV-304 cells.

Journal: Biochimica et biophysica acta 20060301

Title: Substituent effects on enthalpies of formation of nitrogen heterocycles: 2-substituted benzimidazoles and related compounds.

Journal: The journal of physical chemistry. A 20060223

Title: Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation.

Journal: Toxicology 20060215

Title: Immobilization stress induces cell death through production of reactive oxygen species in the mouse cerebral cortex.

Journal: Neuroscience letters 20060109

Title: Beneficial effects of Ebselen on corrosive esophageal burns of rats.

Journal: International journal of pediatric otorhinolaryngology 20060101

Title: Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060101

Title: Lifetime fluorescence method for determining membrane topology of proteins.

Journal: Analytical biochemistry 20060101

Title: In vitro activities of caspofungin, amphotericin B and azoles against Coccidioides posadasii strains from Northeast, Brazil.

Journal: Mycopathologia 20060101

Title: The statins: drug interactions of significance to the dental practitioner.

Journal: Dental update 20060101

Title: Ebselen attenuates oxidative stress in ischemic astrocytes depleted of glutathione. Comparison with glutathione precursors.

Journal: Pharmacological reports : PR 20060101

Title: The protective effects of selenoorganic compounds against peroxynitrite-induced changes in plasma proteins and lipids.

Journal: Cellular & molecular biology letters 20060101

Title: Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection.

Journal: BMC infectious diseases 20060101

Title: [Studies on the correlation of the method currently used by the Japanese Society for Medical Mycology and its modified method with the NCCLS M27-A2 microdilution method for azole susceptibility testing of Candida species].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20060101

Title: A new, broad-spectrum azole antifungal: posaconazole--mechanisms of action and resistance, spectrum of activity.

Journal: Mycoses 20060101

Title: [Antifungals cellular targets and mechanisms of resistance].

Journal: Therapie 20060101

Title: [Emerging azole antifungals].

Journal: Therapie 20060101

Title: In vivo activity of terpinen-4-ol, the main bioactive component of Melaleuca alternifolia Cheel (tea tree) oil against azole-susceptible and -resistant human pathogenic Candida species.

Journal: BMC infectious diseases 20060101

Title: Design and biological evaluation of photo-switchable inhibitors.

Journal: Genome informatics. International Conference on Genome Informatics 20060101

Title: Current status and future of antifungal therapy for systemic mycoses.

Journal: Recent patents on anti-infective drug discovery 20060101

Title: Analysis of pesticides in fruits by pressurized liquid extraction and liquid chromatography-ion trap-triple stage mass spectrometry.

Journal: Journal of chromatography. A 20051209

Title: Skeleton-selective fluorescent chemosensor based on cyclodextrin bearing a 4-amino-7-nitrobenz-2-oxa-1,3-diazole moiety.

Journal: Organic & biomolecular chemistry 20051207

Title: Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta.

Journal: The Journal of pharmacology and experimental therapeutics 20051201

Title: Current state of three-dimensional characterisation of antifungal targets and its use for molecular modelling in drug design.

Journal: International journal of antimicrobial agents 20051201

Title: Identification of the structural requirements of the receptor-binding affinity of diphenolic azoles to estrogen receptors alpha and beta by three-dimensional quantitative structure-activity relationship and structure-activity relationship analysis.

Journal: Journal of medicinal chemistry 20051201

Title: Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors.

Journal: Journal of medicinal chemistry 20051201

Title: Fungal infections of the skin: infection process and antimycotic therapy.

Journal: Current drug targets 20051201

Title: Currently used antimycotics: spectrum, mode of action and resistance occurrence.

Journal: Current drug targets 20051201

Title: Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats.

Journal: Toxicology 20051115

Title: Frequency of potential azole drug-drug interactions and consequences of potential fluconazole drug interactions.

Journal: Pharmacoepidemiology and drug safety 20051101

Title: Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels.

Journal: American journal of physiology. Heart and circulatory physiology 20051101

Title: Azole susceptibility and resistance in Candida dubliniensis.

Journal: Biochemical Society transactions 20051101

Title: Metal ion coordination to azole nucleosides.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20051021

Title: Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+.

Journal: Toxicology 20051015

Title: Compounds for the prevention and treatment of noise-induced hearing loss.

Journal: Drug discovery today 20051001

Title: Versatile access to C-4-substituted 2-amino-1,3-azoles from hydropyridines in oxidative conditions.

Journal: The Journal of organic chemistry 20050930

Title: New multi-1,2,3-selenadiazole aromatic derivatives.

Journal: Molecules (Basel, Switzerland) 20050930

Title: Nano-encapsulation of azole antifungals: potential applications to improve oral drug delivery.

Journal: International journal of pharmaceutics 20050914

Title: Ebselen: a thioredoxin reductase-dependent catalyst for alpha-tocopherol quinone reduction.

Journal: Toxicology and applied pharmacology 20050901

Title: Recent developments in cannabinoid ligands.

Journal: Life sciences 20050819

Title: Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions.

Journal: Journal of the American Chemical Society 20050817

Title: Quantitation of 13 azole fungicides in wine samples by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20050812

Title: Sterol uptake in Candida glabrata: rescue of sterol auxotrophic strains.

Journal: Diagnostic microbiology and infectious disease 20050801

Title: Synthesis, characterization and biological activity of triorganotin 2-phenyl-1,2,3-triazole-4-carboxylates.

Journal: Journal of inorganic biochemistry 20050801

Title: Antifungal treatment in pediatric patients.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20050801

Title: Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.

Journal: Journal of natural products 20050801

Title: CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions.

Journal: The Journal of pharmacology and experimental therapeutics 20050701

Title: Ebselen attenuates haloperidol-induced orofacial dyskinesia and oxidative stress in rat brain.

Journal: Pharmacology, biochemistry, and behavior 20050701

Title: NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1.

Journal: Journal of neurochemistry 20050701

Title: Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

Journal: The Journal of biological chemistry 20050624

Title: Ebselen prevents noise-induced excitotoxicity and temporary threshold shift.

Journal: Neuroscience letters 20050603

Title: Synthesis and characterization of azole isoflavone inhibitors of aromatase.

Journal: Bioorganic & medicinal chemistry 20050602

Title: Organoselenium compounds prevent hyperphosphorylation of cytoskeletal proteins induced by the neurotoxic agent diphenyl ditelluride in cerebral cortex of young rats.

Journal: Toxicology 20050601

Title: Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity.

Journal: Anti-cancer drugs 20050601

Title: Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans.

Journal: Antimicrobial agents and chemotherapy 20050601

Title: Antifungal activities of tacrolimus and azole agents against the eleven currently accepted Malassezia species.

Journal: Journal of clinical microbiology 20050601

Title: Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs.

Journal: The Journal of pharmacy and pharmacology 20050601

Title: Determination of azolic fungicides in wine by solid-phase extraction and high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.

Journal: Journal of chromatography. A 20050527

Title: Selenium compounds prevent the effects of methylmercury on the in vitro phosphorylation of cytoskeletal proteins in cerebral cortex of young rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050501

Title: Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes.

Journal: The Journal of antimicrobial chemotherapy 20050501

Title: Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats.

Journal: The Journal of urology 20050501

Title: Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.

Journal: Journal of biochemistry 20050501

Title: Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates.

Journal: Medical mycology 20050501

Title: The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus.

Journal: Medical mycology 20050501

Title: Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.

Journal: Journal of medicinal chemistry 20050421

Title: Regulation of azole drug susceptibility by Candida albicans protein kinase CK2.

Journal: Molecular microbiology 20050401

Title: Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers.

Journal: Current drug targets. CNS and neurological disorders 20050401

Title: Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina.

Journal: Brain research 20050328

Title: Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.

Journal: The Journal of biological chemistry 20050311

Title: Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen.

Journal: Hearing research 20050301

Title: Synthesis and spectroscopic characterisation of new ESIPT fluorescent protein probes.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050301

Title: [Synthesis of byrazoline fluorescent compounds and studies by infrared spectroscopy].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20050301

Title: Neuroprotective effects of ebselen on experimental spinal cord injury in rats.

Journal: Neurochemical research 20050301

Title: Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20050301

Title: New agents for invasive mycoses in children.

Journal: Current opinion in pediatrics 20050201

Title: Antifungal drugs.

Journal: Treatment guidelines from the Medical Letter 20050201

Title: Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance.

Journal: Antimicrobial agents and chemotherapy 20050201

Title: Involvement of peroxynitrite in capsaicin-induced apoptosis of C6 glioma cells.

Journal: Neuroscience research 20050201

Title: Emerging azole antifungals.

Journal: Expert opinion on emerging drugs 20050201

Title: Second-generation azole antifungal agents.

Journal: Drugs of today (Barcelona, Spain : 1998) 20050201

Title: Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050101

Title: Solid-phase synthesis of 5-amino-1-(substituted thiocarbamoyl)pyrazole and 1,2,4-triazole derivatives via dithiocarbazate linker.

Journal: Journal of combinatorial chemistry 20050101

Title: Characterization and properties of cholesterol desaturases from the ciliate Tetrahymena thermophila.

Journal: The Journal of eukaryotic microbiology 20050101

Title: Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic compound.

Journal: Anticancer research 20050101

Title: [Synthesis and antiviral activity of new 5-substituted 2'-deoxyuridine derivatives].

Journal: Bioorganicheskaia khimiia 20050101

Title: Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats.

Journal: Blood pressure 20050101

Title: Glyoxylic acid and MP-glyoxylate: efficient formaldehyde equivalents in the 3-CC of 2-aminoazines, aldehydes, and isonitriles.

Journal: Organic letters 20041223

Title: Oral Candida isolates in patients undergoing radiotherapy for head and neck cancer: prevalence, azole susceptibility profiles and response to antifungal treatment.

Journal: Oral microbiology and immunology 20041201

Title: Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen.

Journal: Kidney international 20041201

Title: TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

Journal: Eukaryotic cell 20041201

Title: The effects of ebselen on [3H]glutamate uptake by synaptic vesicles from rat brain.

Journal: Brain research 20041119

Title: Protective effects on neuronal cells of mouse afforded by ebselen against oxidative stress at multiple steps.

Journal: Neuroscience letters 20041116

Title: Ebselen augments its peroxidase activity by inducing nrf-2-dependent transcription.

Journal: Archives of biochemistry and biophysics 20041115

Title: Combinations of antifungal agents in therapy--what value are they?

Journal: The Journal of antimicrobial chemotherapy 20041101

Title: Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring.

Journal: Bioorganic & medicinal chemistry 20041101

Title: Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101

Title: Azaanalogues of ebselen as antimicrobial and antiviral agents: synthesis and properties.

Journal: Farmaco (Societa chimica italiana : 1989) 20041101

Title: Combination antifungal therapy: where are we now, and where are we going?

Journal: Oncology (Williston Park, N.Y.) 20041101

Title: Thermodynamic and biophysical characterization of cytochrome P450 BioI from Bacillus subtilis.

Journal: Biochemistry 20041005

Title: Oxidant activity in skeletal muscle fibers is influenced by temperature, CO2 level, and muscle-derived nitric oxide.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041001

Title: Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds.

Journal: Antimicrobial agents and chemotherapy 20041001

Title: Synthesis and anti-tuberculosis activity of N-aryl-C-nitroazoles.

Journal: European journal of medicinal chemistry 20041001

Title: Synthesis and antimycobacterial activity of pyridylmethylsulfanyl and naphthylmethylsulfanyl derivatives of benzazoles, 1, 2, 4-triazole, and pyridine-2-carbothioamide/-2-carbonitrile.

Journal: Archiv der Pharmazie 20041001

Title: Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment.

Journal: Respiratory medicine 20041001

Title: Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid.

Journal: Neurochemical research 20041001

Title: Ebselen protects Ca2+ influx blockage but does not protect glutamate uptake inhibition caused by Hg2+.

Journal: Neurochemical research 20041001

Title: Azoles as Suzuki cross-coupling leaving groups: syntheses of 6-arylpurine 2'-deoxynucleosides and nucleosides from 6-(imidazol-1-yl)- and 6-(1,2,4-triazol-4-yl)purine derivatives.

Journal: Organic letters 20040916

Title: Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose.

Journal: Diabetes 20040901

Title: Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen.

Journal: Journal of the American Society of Nephrology : JASN 20040901

Title: The involvement of oxidative stress in bovine herpesvirus type 4-mediated apoptosis.

Journal: Frontiers in bioscience : a journal and virtual library 20040901

Title: Protection by flavonoids against the peroxynitrite-mediated oxidation of dihydrorhodamine.

Journal: Free radical research 20040901

Title: Interplay among platelet-activating factor, oxidative stress, and group I metabotropic glutamate receptors modulates neuronal survival.

Journal: Journal of neuroscience research 20040815

Title: Organochalcogens affect the glutamatergic neurotransmission in human platelets.

Journal: Neurochemical research 20040801

Title: Quantitation of lanosterol and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS.

Journal: Journal of the American Society for Mass Spectrometry 20040801

Title: Voriconazole: therapeutic review of a new azole antifungal.

Journal: Expert review of anti-infective therapy 20040801

Title: Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans.

Journal: Endocrine research 20040801

Title: Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity.

Journal: The Journal of biological chemistry 20040723

Title: Reaction of bromomethylazoles and tosylmethyl isocyanide. A novel heterocyclization method for the synthesis of the core of marine alkaloids variolins and related azolopyrimidines.

Journal: The Journal of organic chemistry 20040723

Title: Thiocyanate catalyzes myeloperoxidase-initiated lipid oxidation in LDL.

Journal: Free radical biology & medicine 20040715

Title: Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species.

Journal: Free radical biology & medicine 20040715

Title: Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia.

Journal: European journal of pharmacology 20040708

Title: Proliferation of ovarian theca-interstitial cells is modulated by antioxidants and oxidative stress.

Journal: Human reproduction (Oxford, England) 20040701

Title: Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice.

Journal: Biological research for nursing 20040701

Title: Synthesis and fungicidal activity of enantiomerically pure (R)- and (S)-silicon-containing azole fungicides.

Journal: Bioorganic & medicinal chemistry 20040701

Title: Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520.

Journal: The Journal of antimicrobial chemotherapy 20040701

Title: The effect of ebselen on adenine nucleotide hydrolysis by platelets from adult rats.

Journal: Chemico-biological interactions 20040630

Title: Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles.

Journal: Antimicrobial agents and chemotherapy 20040601

Title: [Oxidative stress in a model for experimental diabetic retinopathy: treatment with antioxidants].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20040601

Title: Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: 2. Factors that may have influenced the marked changes in sales volumes during the 1990s.

Journal: Infectious diseases in obstetrics and gynecology 20040601

Title: [Analysis of the mechanism of anti-mycotic activities by azoles potentiated by new erythromycin derivatives].

Journal: The Japanese journal of antibiotics 20040601

Title: Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration.

Journal: Circulation research 20040514

Title: Optically active antifungal azoles: synthesis and antifungal activity of (2R,3S)-2-(2,4-difluorophenyl)-3-(5-[2-[4-aryl-piperazin-1-yl]-ethyl]-tetrazol-2-yl/1-yl)-1-[1,2,4]-triazol-1-yl-butan-2-ol.

Journal: Bioorganic & medicinal chemistry 20040501

Title: Synthesis of [75Se]5-ethoxycarbonyl-4-methyl-1,2,3-selenadiazole.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20040501

Title: Differential effects of the combination of caspofungin and terbinafine against Candida albicans, Candida dubliniensis and Candida kefyr.

Journal: International journal of antimicrobial agents 20040501

Title: Chemoenzymatic preparation of nucleoside triphosphates.

Journal: Current protocols in nucleic acid chemistry 20040501

Title: Antifungal therapy for keratomycoses.

Journal: Expert opinion on pharmacotherapy 20040401

Title: Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040301

Title: History of the development of azole derivatives.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301

Title: Antifungal prophylaxis with azole derivatives.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301

Title: Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies.

Journal: Haematologica 20040301

Title: Newer antifungal agents.

Journal: Indian journal of pediatrics 20040301

Title: [Usefulness of the E-test and its assay conditions in the study of the interaction of antifungal agents. A pilot study].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20040301

Title: Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen.

Journal: Circulation research 20040220

Title: Ebselen inhibits p38 mitogen-activated protein kinase-mediated endothelial cell death by hydrogen peroxide.

Journal: European journal of pharmacology 20040206

Title: Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma.

Journal: Circulation 20040203

Title: Additive pro-oxidative effects of methylmercury and ebselen in liver from suckling rat pups.

Journal: Toxicology letters 20040202

Title: Drug resistance genes and trailing growth in Candida albicans isolates.

Journal: The Journal of antimicrobial chemotherapy 20040201

Title: Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems.

Journal: Antioxidants & redox signaling 20040201

Title: Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

Journal: Antimicrobial agents and chemotherapy 20040201

Title: A new era of antifungal therapy.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040201

Title: Ebselen-mediated protection from single and repeated noise exposure in rat.

Journal: The Laryngoscope 20040201

Title: (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: Simultaneous analysis of esterase and transferase activities in cytosol proteins from the bovine retina by using microscale non-denaturing two-dimensional electrophoresis.

Journal: Biochimica et biophysica acta 20040114

Title: Renal and hepatic ALA-D activity and selected oxidative stress parameters of rats exposed to inorganic mercury and organoselenium compounds.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101

Title: [Drug discovery in the new era: exploratory research on novel antifungal agents].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20040101

Title: In vitro evaluation of glutathione peroxidase (GPx)-like activity and antioxidant properties of some Ebselen analogues.

Journal: Redox report : communications in free radical research 20040101

Title: [Activity of the azole drugs in vitro against strains of Candida albicans with different codes isolated from the digestive tract in children].

Journal: Wiadomosci parazytologiczne 20040101

Title: A novel series of complexones with bis- or biazole structure as mixed ligands of paramagnetic contrast agents for MRI.

Journal: Bioorganic & medicinal chemistry 20031201

Title: Synthesis and biological evaluation of ebselen and its acyclic derivatives.

Journal: Chemical & pharmaceutical bulletin 20031201

Title: Management of Candida species infections in critically ill patients.

Journal: The Lancet. Infectious diseases 20031201

Title: Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola.

Journal: Pest management science 20031201

Title: Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2.

Journal: Journal of neurochemistry 20031201

Title: The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1.

Journal: The Journal of biological chemistry 20031031

Title: Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

Journal: Toxicology letters 20031015

Title: Cobalt-catalyzed arylation of azole heteroarenes via direct C-H bond functionalization.

Journal: Organic letters 20031002

Title: Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro.

Journal: Toxicology 20030930

Title: Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.

Journal: The Journal of biological chemistry 20030919

Title: Generation and function of reactive oxygen species in dendritic cells during antigen presentation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030915

Title: Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20030912

Title: Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase.

Journal: Bioorganic & medicinal chemistry 20030901

Title: Differential modulation of hippocampal chemical-induced injury response by ebselen, pentoxifylline, and TNFalpha-, IL-1alpha-, and IL-6-neutralizing antibodies.

Journal: Journal of neuroscience research 20030815

Title: T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation.

Journal: Free radical biology & medicine 20030815

Title: Kinetic study of azole-bridged dinuclear platinum(II) complexes reacting with a hairpin-stabilized double-stranded oligonucleotide.

Journal: Journal of inorganic biochemistry 20030801

Title: Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase.

Journal: Neuroscience letters 20030731

Title: Design and biological evaluation of novel antioxidants containing N-t-Butyl-N-hydroxylaminophenyl moieties.

Journal: Bioorganic & medicinal chemistry letters 20030721

Title: Ipso- or cine-substitutions of 6-haloimidazo[1,2-a]pyridine derivatives with different azoles depending on the reaction conditions.

Journal: The Journal of organic chemistry 20030711

Title: Ebselen attenuates cochlear damage caused by acoustic trauma.

Journal: Hearing research 20030701

Title: Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs.

Journal: International journal of pharmaceutics 20030618

Title: Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice.

Journal: Toxicology letters 20030605

Title: Efficacy of caspofungin combined with amphotericin B against azole-resistant Candida albicans.

Journal: The Journal of antimicrobial chemotherapy 20030601

Title: A combination chemical and enzymatic approach for the preparation of azole carboxamide nucleoside triphosphate.

Journal: The Journal of organic chemistry 20030516

Title: Dual effect of ebselen on mitochondrial permeability transition.

Journal: Biochemical pharmacology 20030515

Title: Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization.

Journal: Journal of the American Chemical Society 20030507

Title: Preparation and pharmacological profile of 7-(alpha-azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20030505

Title: In vitro and in vivo activity of tea tree oil against azole-susceptible and -resistant human pathogenic yeasts.

Journal: The Journal of antimicrobial chemotherapy 20030501

Title: High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501

Title: Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen.

Journal: Journal of cellular biochemistry 20030501

Title: Identification of genes differentially expressed in association with reduced azole susceptibility in Saccharomyces cerevisiae.

Journal: The Journal of antimicrobial chemotherapy 20030501

Title: Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030501

Title: Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP.

Journal: Experimental biology and medicine (Maywood, N.J.) 20030501

Title: Can the ebselen derivatives catalyze the isomerization of peroxynitrite to nitrate?

Journal: Journal of the American Chemical Society 20030402

Title: Effects of anti-ecdysteroid quaternary derivatives of azole analogues of metyrapone on the post-embryonic development of the red cotton bug (Dysdercus cingulatus F).

Journal: Pest management science 20030401

Title: Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.

Journal: Journal of the American Chemical Society 20030319

Title: Inhibition by ebselen on nitric oxide mediated relaxations in the rat anococcygeus muscle.

Journal: European journal of pharmacology 20030221

Title: Free radical scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells.

Journal: Mutation research 20030205

Title: 11beta-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone.

Journal: Chemico-biological interactions 20030201

Title: Anti-inflammatory and antinociceptive activity of diphenyl diselenide.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201

Title: [Antifungal drug].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030201

Title: Redox catalysts as sensitisers towards oxidative stress.

Journal: FEBS letters 20030130

Title: Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.

Journal: Journal of medicinal chemistry 20030116

Title: Antifungal drug resistance.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030115

Title: Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia.

Journal: Free radical biology & medicine 20030101

Title: Phenotyping of Cryptococcus neoformans strains in Bergamo, Italy (1985-2000).

Journal: The new microbiologica 20030101

Title: Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives.

Journal: European journal of medicinal chemistry 20030101

Title: [Attack point of ergosterol biosynthesis. Drugs and pharmacology].

Journal: Pharmazie in unserer Zeit 20030101

Title: Microbial natural products as a source of antifungals.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030101

Title: [Azole resistance in Candida spp].

Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20030101

Title: Voltage-dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes.

Journal: Journal of biochemical and molecular toxicology 20030101

Title: [Cytochrome P450 3A4 and Benzodiazepines].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20030101

Title: [New systemic antifungal drugs: mechanisms of action, drug interactions and side effects].

Journal: Mycoses 20030101

Title: [Effect of azole derivatives on lucigenin-dependent microsome chemiluminescence].

Journal: Biomeditsinskaia khimiia 20030101

Title: Synthesis of silicon-containing azole derivatives with magnesium bromide diethyl etherate, and an investigation of their fungicidal activities.

Journal: Bioorganic & medicinal chemistry 20021201

Title: [Clinical relevance of mechanisms of antifungal drug resistance in filamentous fungi].

Journal: Enfermedades infecciosas y microbiologia clinica 20021201

Title: Inhibitory effects of 1,3-selenazol-4-one derivatives on mushroom tyrosinase.

Journal: Chemical & pharmaceutical bulletin 20021201

Title: Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.

Journal: Japanese journal of pharmacology 20021201

Title: Deeply invasive candidiasis.

Journal: Infectious disease clinics of North America 20021201

Title: [Present status and future prospects of azole antifungal agents in Japan].

Journal: The Japanese journal of antibiotics 20021201

Title: Tin-free radical sequences under acidic conditions. Convergent access to azole-containing structures.

Journal: Organic letters 20021128

Title: Synthesis of N-cycloalkenylazoles.

Journal: The Journal of organic chemistry 20021115

Title: Synthetic applications of azolium ylides to a traceless solid-phase synthesis of 2-substituted azoles.

Journal: Organic letters 20021114

Title: Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation.

Journal: Antimicrobial agents and chemotherapy 20021101

Title: Clinical relevance of mechanisms of antifungal drug resistance in yeasts.

Journal: Enfermedades infecciosas y microbiologia clinica 20021101

Title: A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase.

Journal: The Journal of biological chemistry 20021018

Title: Has antifungal susceptibility testing come of age?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021015

Title: Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals.

Journal: Bioorganic & medicinal chemistry letters 20021007

Title: Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling.

Journal: Molecular microbiology 20021001

Title: Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes.

Journal: Microbiology (Reading, England) 20021001

Title: The neuroprotectant ebselen inhibits oxidative DNA damage induced by dopamine in the presence of copper ions.

Journal: Neuroscience letters 20020913

Title: Intrahippocampal infusion of ebselen impairs retention of an inhibitory avoidance task in rats.

Journal: European journal of pharmacology 20020913

Title: Treatment of azole-resistant oropharyngeal candidiasis with topical amphotericin B.

Journal: The Annals of pharmacotherapy 20020901

Title: Antifungal drug resistance to azoles and polyenes.

Journal: The Lancet. Infectious diseases 20020901

Title: Role of oxygen and nitrogen species in experimental uveitis: anti-inflammatory activity of the synthetic antioxidant ebselen.

Journal: Free radical biology & medicine 20020901

Title: Tolerability, safety and efficacy of conventional amphotericin B administered by 24-hour infusion to lung transplant recipients.

Journal: Swiss medical weekly 20020810

Title: Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells.

Journal: British journal of pharmacology 20020801

Title: Effects of C-nitropyrazoles and C-nitroazoles on ocular blood flow and retinal function recovery after ischemic insult.

Journal: Acta pharmacologica Sinica 20020801

Title: Ebselen protects against the reduction in levels of drug-metabolizing enzymes in livers of rats with deoxycholic acid-induced liver injury.

Journal: Pharmacology & toxicology 20020801

Title: Unsymmetrical 1,1'-disubstituted ferrocenes: synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) chelates of ferrocenyl -1-thiadiazolo-1'-tetrazole, -1-thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with antimicrobial properties.

Journal: Journal of enzyme inhibition and medicinal chemistry 20020801

Title: Effects of angiotensin II type 1 receptor antagonist, YM358, on cardiac hypertrophy and dysfunction after myocardial infarction in rats.

Journal: Biological & pharmaceutical bulletin 20020701

Title: Effect of Micafungin (FK463) on Candida albicans adherence to epithelial cells.

Journal: Chemotherapy 20020701

Title: Effects of antioxidants on surfactant peroxidation by stimulated human polymorphonuclear leukocytes.

Journal: Free radical research 20020701

Title: Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.

Journal: Circulation research 20020628

Title: In vitro activity of caspofungin (MK-0991) against Candida albicans clinical isolates displaying different mechanisms of azole resistance.

Journal: Journal of clinical microbiology 20020601

Title: Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB.

Journal: Journal of neurochemistry 20020601

Title: Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts.

Journal: Carcinogenesis 20020601

Title: The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes.

Journal: Toxicology letters 20020528

Title: Comparative toxicological assessment of a water-soluble azole administered both orally and by intravenous continuous infusion in cynomolgus monkeys.

Journal: The Journal of toxicological sciences 20020501

Title: Homozygosity at the Candida albicans MTL locus associated with azole resistance.

Journal: Microbiology (Reading, England) 20020401

Title: Exposure to ebselen changes glutamate uptake and release by rat brain synaptosomes.

Journal: Neurochemical research 20020401

Title: Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain.

Journal: Neurochemical research 20020401

Title: Do azoles and chloroquine share similar mechanisms of antimalarial action?

Journal: Trends in parasitology 20020401

Title: Diagnosis and treatment of invasive pulmonary aspergillosis in neutropenic patients.

Journal: The European respiratory journal 20020401

Title: Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway.

Journal: Science (New York, N.Y.) 20020329

Title: Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b]pyridin-5-one.

Journal: Journal of the American Chemical Society 20020320

Title: Ebselen has dehydroascorbate reductase and thioltransferase-like activities.

Journal: Biochemical and biophysical research communications 20020301

Title: Ebselen suppresses late airway responses and airway inflammation in guinea pigs.

Journal: Free radical biology & medicine 20020301

Title: Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds.

Journal: European journal of medicinal chemistry 20020301

Title: Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis.

Journal: Journal of mass spectrometry : JMS 20020301

Title: Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat.

Journal: Neuroscience letters 20020201

Title: Molecular basis of resistance to azole antifungals.

Journal: Trends in molecular medicine 20020201

Title: Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences.

Journal: The Lancet. Infectious diseases 20020201

Title: Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis.

Journal: The Journal of biological chemistry 20020125

Title: Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties.

Journal: Journal of medicinal chemistry 20020117

Title: Formation of active oxygen species and lipid peroxidation induced by hypochlorite.

Journal: Archives of biochemistry and biophysics 20020115

Title: Analytical and semipreparative enantiomeric separation of azole antifungal agents by high-performance liquid chromatography on polysaccharide-based chiral stationary phases. Application to in vitro biological studies.

Journal: Journal of chromatography. A 20020104

Title: Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology.

Journal: Journal of medicinal chemistry 20020103

Title: The impact of polyene, azole, and DNA analogue antimycotics on the cell surface hydrophobicity of Candida albicans and Candida tropicalis in HIV infection.

Journal: Mycopathologia 20020101

Title: Detection of human P-glycoprotein-like molecule in azole-resistant Candida albicans from HIV+ patients.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20020101

Title: Action of peroxidases on protein hydroperoxides.

Journal: Redox report : communications in free radical research 20020101

Title: Study of the thermal behavior of azidohetarenes with differential scanning calorimetry.

Journal: Journal of biochemical and biophysical methods 20020101

Title: Overview: fungal infections in the transplant patient.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20020101

Title: Fungal infection in liver transplantation.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20020101

Title: Synthesis of some new azoles and azines and their condensed derivatives.

Journal: Bollettino chimico farmaceutico 20020101

Title: Impact of strobilurins on physiology and yield formation of wheat.

Journal: Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101

Title: A novel dicyclodextrinyl ditelluride compound with antioxidant activity.

Journal: FEBS letters 20011102

Title: Oxidative and nitrosative stress in acute renal ischemia.

Journal: American journal of physiology. Renal physiology 20011101

Title: Extrusion of fluorescein diacetate by multidrug-resistant Candida albicans.

Journal: Mycoses 20011101

Title: Anti-oxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats.

Journal: Journal of gastroenterology and hepatology 20011101

Title: Update on antifungal agents.

Journal: The Pediatric infectious disease journal 20011001

Title: Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901

Title: Prevalence of vaginal colonization by drug-resistant Candida species in college-age women with previous exposure to over-the-counter azole antifungals.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901

Title: Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia.

Journal: Stroke 20010901

Title: Optically active antifungal azoles. XII. Synthesis and antifungal activity of the water-soluble prodrugs of 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone.

Journal: Chemical & pharmaceutical bulletin 20010901

Title: Carbon disulfide promoted reactions of 2-chloro-4,5-dihydro-imidazole with some N-nucleophiles.

Journal: Chemical & pharmaceutical bulletin 20010901

Title: The neuroprotective agent ebselen modifies NMDA receptor function via the redox modulatory site.

Journal: Journal of neurochemistry 20010901

Title: The KEX2 gene of Candida glabrata is required for cell surface integrity.

Journal: Molecular microbiology 20010901

Title: Potential application of plant lipid transfer proteins for drug delivery.

Journal: Biochemical pharmacology 20010901

Title: Synthesis and biological evaluation of azole derivatives, analogues of bifonazole, with a phenylisoxazolyl or phenylpyrimidinyl moiety.

Journal: Farmaco (Societa chimica italiana : 1989) 20010901

Title: Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis.

Journal: Biochemical pharmacology 20010615

Title: Mitochondrial membrane potential in density-separated trout erythrocytes exposed to oxidative stress in vitro.

Journal: Biochimica et biophysica acta 20010601

Title: Comparisons of pKa and log P values of some carboxylic and phosphonic acids: synthesis and measurement.

Journal: AAPS pharmSci 20010601

Title: Therapy for fungal infections in leukemia.

Journal: Current oncology reports 20010501

Title: The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

Journal: Journal of biochemistry 20010501

Title: OxLDL induces macrophage gamma-GCS-HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis.

Journal: Journal of lipid research 20010501

Title: An old activity in the cytochrome P450 superfamily (CYP51) and a new story of drugs and resistance.

Journal: Biochemical Society transactions 20010501

Title: Comparison of the angiotensin II type 1-receptor antagonist YM358 and the angiotensin-converting enzyme inhibitor enalapril in rats with cardiac volume overload.

Journal: Japanese journal of pharmacology 20010501

Title: Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010401

Title: Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.

Journal: Japanese journal of cancer research : Gann 20010401

Title: Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80.

Journal: European journal of pharmacology 20010302

Title: The selenoorganic compound ebselen suppresses liver injury induced by Propionibacterium acnes and lipopolysaccharide in rats.

Journal: International journal of molecular medicine 20010301

Title: Itraconazole-enhanced vincristine neurotoxicity in a child with acute lymphoblastic leukemia.

Journal: Pediatric hematology and oncology 20010301

Title: [The activity of systemic antimycotic drug combinations].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20010301

Title: [Molecular mechanize and clinical feature of azole-resistant Candida albicans strains and new strategy of treatment].

Journal: The Japanese journal of antibiotics 20010301

Title: Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons.

Journal: Neuroscience letters 20010223

Title: Ebselen prevents early alcohol-induced liver injury in rats.

Journal: Free radical biology & medicine 20010215

Title: Extracts from 'Clinical evidence': Athlete's foot and fungally infected toenails.

Journal: BMJ (Clinical research ed.) 20010203

Title: Effect of ketoconazole, itraconazole and fluconazole on the gastrointestinal colonization of mice by Candida albicans.

Journal: Journal of chemotherapy (Florence, Italy) 20010201

Title: Antifungal and immunomodulating activities of 1,4-benzothiazine azole derivatives: review.

Journal: Journal of chemotherapy (Florence, Italy) 20010201

Title: The effects of thiol compounds and ebselen on nitric oxide activity in rat aortic vascular responses.

Journal: Journal of autonomic pharmacology 20010201

Title: [Metabolic interactions with statins].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120

Title: Reactive oxygen species and caspase activation mediate silica-induced apoptosis in alveolar macrophages.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010101

Title: The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients.

Journal: British journal of haematology 20010101

Title: Clinical applicability of antifungal susceptibility testing on non-Candida albicans species in hospitalized patients.

Journal: Diagnostic microbiology and infectious disease 20010101

Title: Selective inhibition of vitamin D hydroxylases in human keratinocytes.

Journal: Steroids 20010101

Title: Antiviral activity of the products of cyclization of dimethyl 2-[(1-arylamino-1-arylmethylidene)hydrazono]succinate.

Journal: European journal of medicinal chemistry 20010101

Title: In vitro susceptibility of 137 Candida sp. isolates from HIV positive patients to several antifungal drugs.

Journal: Mycopathologia 20010101

Title: Treatment of systemic fungal infections in older patients: achieving optimal outcomes.

Journal: Drugs & aging 20010101

Title: Oral colonization by Candida spp. among AIDS household contacts.

Journal: Mycoses 20010101

Title: Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer 344 rats.

Journal: Carcinogenesis 20001201

Title: Optically active antifungal azoles. X. Synthesis and antifungal activity of N.

Journal: Chemical & pharmaceutical bulletin 20001201

Title: Bactericidal and inhibitory effects of azole antifungal compounds on Mycobacterium smegmatis.

Journal: FEMS microbiology letters 20001115

Title: Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors.

Journal: Antimicrobial agents and chemotherapy 20001001

Title: A new class of antifungal agents. Synthesis and antimycotic activity of disubstituted N-azolylamines.

Journal: Archiv der Pharmazie 20000901

Title: Efficacy of FK463, a (1,3)-beta-D-glucan synthase inhibitor, in disseminated azole-resistant candida albicans infection in mice.

Journal: Antimicrobial agents and chemotherapy 20000601

Title: In vitro synergism between nyasol, an active compound isolated from Anemarrhena asphodeloides, and azole agents against Candida albicans.

Journal: Planta medica 20000601

Title: Current and emerging azole antifungal agents.

Journal: Clinical microbiology reviews 19990101

Title: Azole derivatives of 1,4-benzothiazine as antifungal agents.

Journal: Bioorganic & medicinal chemistry 19980101

Title: Prolongation of the QT interval related to cisapride-diltiazem interaction.

Journal: Pharmacotherapy 19980101

Title: Antifungal, antibacterial, antiviral and cytotoxic activity of novel thio- and seleno-azoles.

Journal: Pharmacological research 19970901

Title: In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species.

Journal: Antimicrobial agents and chemotherapy 19970701

Title: In vitro activity of a new pneumocandin antifungal agent, L-733,560 against azole-susceptible and -resistant Candida and Torulopsis species.

Journal: Antimicrobial agents and chemotherapy 19951201

Title: Molecular actions of ebselen--an antiinflammatory antioxidant.

Journal: General pharmacology 19951001

Title: Synthesis and antifungal activity of new azole derivatives containing an N-acylmorpholine ring.

Journal: Journal of medicinal chemistry 19950929

Title: Optically active antifungal azoles. IV. Synthesis and antifungal activity of (2R,3R)-3-azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanols.

Journal: Chemical & pharmaceutical bulletin 19950301

Title: Optically active antifungal azoles. V. Synthesis and antifungal activity of stereoisomers of 3-azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2- butanols.

Journal: Chemical & pharmaceutical bulletin 19950301

Title: Interaction of ebselen with glutathione S-transferase and papain in vitro.

Journal: Biochemical pharmacology 19940315

Title: PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity.

Journal: Biochemical pharmacology 19920818

Title: Plant sterol biosynthesis: novel potent and selective inhibitors of cytochrome P450-dependent obtusifoliol 14 alpha-methyl demethylase.

Journal: Archives of biochemistry and biophysics 19920815

Title: In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin.

Journal: Antimicrobial agents and chemotherapy 19920801

Title: Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo.

Journal: Antimicrobial agents and chemotherapy 19920601

Title: Saperconazole: in vitro and in vivo anticandidal activity.

Journal: Chemotherapy 19920101

Title: Comparison of SCH 39304 and its isomers, RR 42427 and SS 42426, for treatment of murine cryptococcal and coccidioidal meningitis.

Journal: Antimicrobial agents and chemotherapy 19920101

Title: Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis.

Journal: Pancreas 19910501

Title: Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.

Journal: Hypertension (Dallas, Tex. : 1979) 19900501

Title: Increased external carotid artery blood flow in headache patients induced by cilostazol. Preliminary communication.

Journal: Arzneimittel-Forschung 19900501

Title: Two distinct angiotensin II receptor binding sites in rat adrenal revealed by new selective nonpeptide ligands.

Journal: Molecular pharmacology 19900301

Title: Overview of medically important antifungal azole derivatives.

Journal: Clinical microbiology reviews 19880401

Title: Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds.

Journal: Journal of medicinal chemistry 19870601

Title: In vitro activity of ME1401, a new antifungal agent.

Journal: Antimicrobial agents and chemotherapy 19861101

Title: Synthesis of tetrazole ribonucleosides and their evaluation as antiviral agents. 2. 5-Amino-1-(beta-D-ribofuranosyl)-1H-tetrazole and 5-amino-2-(beta-D-ribofuranosyl)-2H-tetrazole.

Journal: Journal of medicinal chemistry 19760801

Title: Synthesis of tetrazole ribonucleosides and their evaluation as antiviral agents.

Journal: Journal of medicinal chemistry 19760201

Title: Urinary calculi with methazolamide therapy.

Journal: Documenta ophthalmologica. Advances in ophthalmology 19730221

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SDS
Tags:421581-70-6 Molecular Formula|421581-70-6 MDL|421581-70-6 SMILES|421581-70-6 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole