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4250-77-5,MFCD00017485
Catalog No.:AA003N5W

4250-77-5 | 6-Hydroxyflavanone

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Purity
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1g
>98.0%(GC)(T)
in stock  
$59.00   $41.00
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5g
>98.0%(GC)(T)
in stock  
$189.00   $132.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003N5W
Chemical Name:
6-Hydroxyflavanone
CAS Number:
4250-77-5
Molecular Formula:
C15H12O3
Molecular Weight:
240.2540
MDL Number:
MFCD00017485
SMILES:
Oc1ccc2c(c1)C(=O)CC(O2)c1ccccc1
Properties
Properties
 
Storage:
Room Temperature;Light sensitive;Keep in dry area;  

Computed Properties
 
Complexity:
309  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.7  

Downstream Synthesis Route

[1]Ferreira,LeonardoMiziaraBarboza;Kobelnik,Marcelo;Regasini,LuisOctavio;Dutra,LuizAntonio;daSilvaBolzani,Vanderlan;Ribeiro,ClóvisAugusto[JournalofThermalAnalysisandCalorimetry,2017,vol.127,#2,p.1605-1610]

[2]Robertsonetal.[JournaloftheChemicalSociety,1954,p.3137,3141]

[3]Cui,Wei;Zhang,Ji;Wang,Qian;Gao,Kai;Zhang,Wei;Yang,Jian[JournalofChemicalResearch,2014,vol.38,#11,p.686-689]

[1]Row;Rao[CurrentScience,1956,vol.25,p.393]

[1]Row;Rao[CurrentScience,1956,vol.25,p.393]

Literature

Title: Synthetic flavanones augment the anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

Journal: Molecules (Basel, Switzerland) 20121001

Title: Evaluation of novel amylose and cellulose-based chiral stationary phases for the stereoisomer separation of flavanones by means of nano-liquid chromatography.

Journal: Analytica chimica acta 20120813

Title: Microbial transformations of 7-hydroxyflavanone.

Journal: TheScientificWorldJournal 20120101

Title: Bioconversion of 7-hydroxyflavanone: isolation, characterization and bioactivity evaluation of twenty-one phase I and phase II microbial metabolites.

Journal: Chemical & pharmaceutical bulletin 20120101

Title: Physicochemical characterization and antioxidant activity of melanin from a novel strain of Aspergillus bridgeri ICTF-201.

Journal: Letters in applied microbiology 20110901

Title: Optical isomer separation of flavanones and flavanone glycosides by nano-liquid chromatography using a phenyl-carbamate-propyl-beta-cyclodextrin chiral stationary phase.

Journal: Journal of chromatography. A 20100212

Title: Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.

Journal: Bioorganic & medicinal chemistry letters 20090815

Title: Relationships between the structures of flavanone derivatives and their effects in enhancing early growth response-1 gene expression.

Journal: Bioorganic & medicinal chemistry letters 20090415

Title: Screening of flavonoids as candidate antibiotics against Enterococcus faecalis.

Journal: Journal of natural products 20090401

Title: Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.

Journal: Journal of medicinal chemistry 20080724

Title: Microbial metabolism part 9. Structure and antioxidant significance of the metabolites of 5,7-dihydroxyflavone (chrysin), and 5- and 6-hydroxyflavones.

Journal: Chemical & pharmaceutical bulletin 20080401

Title: Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.

Journal: Organic & biomolecular chemistry 20060621

Title: Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

Journal: Journal of medicinal chemistry 20050908

Title: Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

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SDS
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