[1]Warren;Smiles[JournaloftheChemicalSociety,1931,p.914,919]
[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1953,vol.73,p.1083 Chem.Abstr.,1954,p.12053
[1]CurrentPatentAssignee:DUPONTDENEMOURSINC-US2216840,1938,AStevenson;Smiles[JournaloftheChemicalSociety,1930,p.1740,1744][JournaloftheChemicalSociety,1931,p.718,722]
[2]CurrentPatentAssignee:DUPONTDENEMOURSINC-US2216840,1938,AStevenson;Smiles[JournaloftheChemicalSociety,1930,p.1740,1744][JournaloftheChemicalSociety,1931,p.718,722]
[1]Warren;Smiles[JournaloftheChemicalSociety,1931,p.1192,1195]
[1]Warren;Smiles[JournaloftheChemicalSociety,1931,p.1192,1195]
Title: Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor.
Journal: ACS medicinal chemistry letters 20150709
Title: p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112.
Journal: PloS one 20110101
Title: An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.
Journal: Molecular cancer therapeutics 20090901
Title: An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.
Journal: Chemistry & biology 20080401
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Viaud J, et al. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8(9):2559-65.
Title: Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009 Jul;218(1):137-44.
Title: Deacon SW, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol. 2008 Apr;15(4):322-31.