Home Amines 43029-19-2
43029-19-2,MFCD01646052
Catalog No.:AA003IV8

43029-19-2 | 2-Amino-3-hydroxypyrazine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$16.00   $11.00
- +
1g
98%
in stock  
$27.00   $19.00
- +
5g
98%
in stock  
$135.00   $95.00
- +
10g
98%
in stock  
$228.00   $160.00
- +
25g
98%
in stock  
$552.00   $387.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003IV8
Chemical Name:
2-Amino-3-hydroxypyrazine
CAS Number:
43029-19-2
Molecular Formula:
C4H5N3O
Molecular Weight:
111.1020
MDL Number:
MFCD01646052
SMILES:
O=c1[nH]ccnc1N
NSC Number:
263764
Properties
Properties
 
BP:
538.9°C at 760 mmHg  
Form:
Solid  
MP:
300-301°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
170  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
-1.3  

Literature

Title: P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position.

Journal: Bioorganic & medicinal chemistry letters 20110301

Title: P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold.

Journal: Bioorganic & medicinal chemistry letters 20050602

Title: Synthesis of 3-aminopyrazinone mediated by 2-pyridylthioimidate-ZnCl2 complexes. Development of an efficient route to a thrombin inhibitor.

Journal: The Journal of organic chemistry 20031114

Title: Bioactivation of the 3-amino-6-chloropyrazinone ring in a thrombin inhibitor leads to novel dihydro-imidazole and imidazolidine derivatives: structures and mechanism using 13C-labels, mass spectrometry, and NMR.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.

Journal: Journal of medicinal chemistry 20030213

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Tags:43029-19-2 Molecular Formula|43029-19-2 MDL|43029-19-2 SMILES|43029-19-2 2-Amino-3-hydroxypyrazine