Home Amines 43029-19-2
43029-19-2,MFCD01646052
Catalog No.:AA003IV8
43029-19-2 | 2-Amino-3-hydroxypyrazine
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1g
>95%
in stock  
$67.00   $47.00
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5g
98%
in stock  
$272.00   $190.00
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25g
98%
in stock  
$1,104.00   $773.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003IV8
Chemical Name:
2-Amino-3-hydroxypyrazine
CAS Number:
43029-19-2
Molecular Formula:
C4H5N3O
Molecular Weight:
111.1020
MDL Number:
MFCD01646052
IUPAC Name:
3-amino-1H-pyrazin-2-one
InChI:
InChI=1S/C4H5N3O/c5-3-4(8)7-2-1-6-3/h1-2H,(H2,5,6)(H,7,8)
InChI Key:
KQLHRXQKORXSTC-UHFFFAOYSA-N
SMILES:
O=c1[nH]ccnc1N
NSC Number:
263764
Properties
Computed Properties
 
Complexity:
170  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
111.043g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
111.104g/mol
Monoisotopic Mass:
111.043g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
67.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.3  

Synonyms
 
3-aminopyrazin-2-ol 
43029-19-2 
SCHEMBL392829 
AC1L80B0 
CTK7E1226 
KS-00000DQB 
DTXSID50312867 
2-Amino-3-hydroxypyrazine, 95% 
BCP23242 
ANW-51906 
CA-056 
CA0086 
2-Amino-3-hydroxypyrazine 
MFCD01646052 
ZINC17061495 
AKOS005207101 
AKOS006279265 
AB51505 
CM10654 
CS-W019050 
NSC-263764 
QC-6890 
AJ-69927 
3-AMINOPYRAZIN-2(1H)-ONE 
AK-23582 
AS-30735 
BR-23582 
SC-45040 
SY021602 
AB0024896 
DB-070388 
ST2410479 
TR-016741 
4CH-002799 
3-AMINO-2(1H)-PYRAZINONE 
AM20070354 
FT-0646221 
W6256 
A23258 
S-4886 
MFCD09754023 (95+%) 
AC-907/30002023 
C4H5N3O 
CID319470 
ACN-029304 
aminopyrazinone 
2(1H)-Pyrazinone, 3-amino- (9CI) 
3-amino-1H-pyrazin-2-one 
NSC263764 
3-Amino-2-pyrazinol 
3-amino-2-hydroxypyrazine 
Literature

Title: P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position.

Journal: Bioorganic & medicinal chemistry letters 20110301

Title: P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold.

Journal: Bioorganic & medicinal chemistry letters 20050602

Title: Synthesis of 3-aminopyrazinone mediated by 2-pyridylthioimidate-ZnCl2 complexes. Development of an efficient route to a thrombin inhibitor.

Journal: The Journal of organic chemistry 20031114

Title: Bioactivation of the 3-amino-6-chloropyrazinone ring in a thrombin inhibitor leads to novel dihydro-imidazole and imidazolidine derivatives: structures and mechanism using 13C-labels, mass spectrometry, and NMR.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.

Journal: Journal of medicinal chemistry 20030213

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