Title: Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
Journal: The Journal of pharmacology and experimental therapeutics 20120801
Title: Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.
Journal: PloS one 20120101
Title: Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells.
Journal: Molecular pharmacology 20111101
Title: Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits.
Journal: Journal of cardiovascular pharmacology 20110201
Title: Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.
Journal: Molecular pharmacology 20110101
Title: Enhanced repolarization capacity: new potential antiarrhythmic strategy based on HERG channel activation.
Journal: Current medicinal chemistry 20110101
Title: Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels.
Journal: British journal of pharmacology 20101001
Title: Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.
Journal: The Journal of physiology 20090515
Title: Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells.
Journal: Molecular pharmacology 20081201
Title: Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest.
Journal: Circulation 20080930
Title: Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.
Journal: Cardiovascular research 20080701
Title: Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243).
Journal: Molecular pharmacology 20080601
Title: Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.
Journal: Acta physiologica (Oxford, England) 20080501
Title: Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.
Journal: Heart rhythm 20080501
Title: Erg K+ channels modulate contractile activity in the bovine epididymal duct.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080301
Title: Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells.
Journal: Molecular vision 20080101
Title: Activation of ERG2 potassium channels by the diphenylurea NS1643.
Journal: Neuropharmacology 20070801
Title: Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
Journal: Molecular pharmacology 20060201
Title: Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Journal: Molecular pharmacology 20060101
Title: Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+.
Journal: Neuropharmacology 19960101
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