Catalog No.:AA003G9R

4546-70-7 | 2,6-Diaminopurine-2'-deoxyriboside

Name: Name:2,6-Diaminopurine-2'-deoxyriboside
Brand: AABLOCKS
SKU: AA003G9R
Availability: InStock
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250mg

95%

in stock

$7.00 $5.00

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95%

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$19.00 $14.00

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95%

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$60.00 $42.00

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25g

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA003G9R

Chemical Name:

2,6-Diaminopurine-2'-deoxyriboside

CAS Number:

4546-70-7

Molecular Formula:

C10H14N6O3

Molecular Weight:

266.2566

MDL Number:

MFCD00047240

SMILES:

OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2c1nc(N)nc2N

Properties

BP:

748.4°C at 760 mmHg

Form:

Solid

MP:

211-213°C

Storage:

Inert atmosphere;2-8℃;

Computed Properties

Complexity:

334

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

-0.5

Downstream Synthesis Route

4546-70-7

17859-53-9

156549-47-2

[1]Cano;Goodman;Eritja[NucleosidesandNucleotides,1994,vol.13,#1-3,p.501-509]

4546-70-7

106449-56-3

[1]Jurczyk,SimonaC.;Kodra,JanosT.;DavidRozzell;Benner,StevenA.;Battersby,ThomasR.[HelveticaChimicaActa,1998,vol.81,#5,p.793-811]

[2]Seela;Gabler[HelveticaChimicaActa,1994,vol.77,#3,p.622-630]

4546-70-7

116113-30-5

[1]Tarussowa,NataliaB.;Dyatkina,NataliaB.;Janta-Lipinski,Martinvon;Langen,Peter[ZeitschriftfurChemie,1987,vol.27,#10,p.366-367]

128790-76-1

4546-70-7

[1]Gao,Hetian;Fathi,Reza;Gaffney,BarbaraL.;Goswami,Bhaswati;Kung,Pei-Pei;etal.[JournalofOrganicChemistry,1992,vol.57,#25,p.6954-6959]

961-07-9

4546-70-7

[1]Fathi;Goswami;Kung;Gaffney;Jones[TetrahedronLetters,1990,vol.31,#3,p.319-322]

[2]Seela;Gabler[HelveticaChimicaActa,1994,vol.77,#3,p.622-630]

Literature

Title: Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases.

Journal: Biochemistry 20041207

Title: The crystal structure of a high affinity RNA stem-loop complexed with the bacteriophage MS2 capsid: further challenges in the modeling of ligand-RNA interactions.

Journal: RNA (New York, N.Y.) 20041101

Title: 2-Amino-alpha-2'-deoxyadenosine increased duplex stability of methoxyethylphosphoramidate alpha-oligodeoxynucleotides with RNA target.

Journal: Bioorganic & medicinal chemistry letters 20020603

Title: A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities.

Journal: Journal of medicinal chemistry 19970704

Title: Nucleic acid related compounds. 57. Synthesis, x-ray crystal structure, lipophilic partition properties, and antiretroviral activities of anomeric 3'-azido-2',3'-dideoxy-2,6-diaminopurine ribosides.

Journal: Journal of medicinal chemistry 19890801

Title: Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.

Journal: Journal of medicinal chemistry 19881001

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