Home Fluorides 455-36-7
455-36-7,MFCD00000338
Catalog No.:AA003JE9

455-36-7 | 3'-Fluoroacetophenone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
97%
in stock  
$13.00   $9.00
- +
10g
97%
in stock  
$16.00   $11.00
- +
25g
97%
in stock  
$19.00   $14.00
- +
100g
97%
in stock  
$75.00   $53.00
- +
500g
97%
in stock  
$373.00   $261.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003JE9
Chemical Name:
3'-Fluoroacetophenone
CAS Number:
455-36-7
Molecular Formula:
C8H7FO
Molecular Weight:
138.1390
MDL Number:
MFCD00000338
SMILES:
Fc1cccc(c1)C(=O)C
NSC Number:
88301
Properties
Properties
 
BP:
204°C at 760 mmHg  
Form:
Liquid  
MP:
-3 °C  
Refractive Index:
n20/D 1.509(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
133  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.8  

Upstream Synthesis Route

[1]Patent:US5176737,1993,A,

[1]AdvancedSynthesisandCatalysis,2005,vol.347,#7-8,p.1027-1034

[1]BioorganicandMedicinalChemistry,2013,vol.21,#17,p.5064-5075

[2]Patent:WO2014/179401,2014,A1,.Locationinpatent:Page/Pagecolumn9;14;15

[3]JournalofMedicinalChemistry,1997,vol.40,#19,p.3049-3056

[4]EuropeanJournalofOrganicChemistry,2015,vol.2015,#17,p.3656-3660

[5]ChemicalCommunications,2017,vol.53,#58,p.8136-8139

[6]OrganicandBiomolecularChemistry,2018,vol.16,#25,p.4683-4687

[1]RussianJournalofOrganicChemistry,2003,vol.39,#11,p.1581-1586

[1]TetrahedronLetters,2012,vol.53,#2,p.191-195

[2]JournalofMedicinalChemistry,2014,vol.57,#15,p.6572-6582

[3]Patent:WO2008/46598,2008,A1,.Locationinpatent:Page/Pagecolumn92

[4]RSCAdvances,2014,vol.4,#107,p.62308-62320

[5]JournalofOrganicChemistry,2013,vol.78,#14,p.7312-7317

[6]Patent:CN107629022,2018,A,.Locationinpatent:Paragraph0454;0455;0456;0457

[7]JournalofMedicinalChemistry,2013,vol.56,#1,p.123-149

[8]Arzneimittel-Forschung/DrugResearch,2001,vol.51,#7,p.569-573

[9]BioorganicandMedicinalChemistryLetters,2007,vol.17,#5,p.1291-1295

[10]Patent:EP1357116,2003,A1,.Locationinpatent:Page/Pagecolumn9

[11]Patent:EP1043319,2000,A1,

[12]Patent:US2006/14958,2006,A1,.Locationinpatent:Page/Pagecolumn13

[13]Patent:WO2012/27965,2012,A1,.Locationinpatent:Page/Pagecolumn27-28

[14]BioorganicandMedicinalChemistryLetters,2013,vol.23,#24,p.6764-6768

[15]BioorganicandMedicinalChemistry,2014,vol.22,#2,p.692-702

[16]MedicinalChemistryResearch,2014,vol.23,#1,p.259-268

[17]OrganicLetters,2014,vol.16,#1,p.302-305

[18]ChemicalCommunications,2014,vol.50,#51,p.6726-6728

[19]MedChemComm,2015,vol.6,#6,p.1036-1042

[20]ChemicalCommunications,2016,vol.52,#29,p.5152-5155

[21]Phosphorus,SulfurandSiliconandtheRelatedElements,2016,vol.191,#8,p.1166-1173

[22]BioorganicandMedicinalChemistryLetters,2016,vol.26,#15,p.3669-3674

[23]OrganicandBiomolecularChemistry,2016,vol.14,#34,p.8026-8029

[24]Patent:CN105669586,2016,A,.Locationinpatent:Paragraph0066

[25]JournalofMedicinalChemistry,2017,vol.60,#4,p.1591-1597

[26]OrganicLetters,2017,vol.19,#8,p.1994-1997

[27]BioorganicandMedicinalChemistry,2017,vol.25,#13,p.3298-3314

[28]OrganicLetters,2017,vol.19,#11,p.2877-2880

[29]ChemicalCommunications(Cambridge,UnitedKingdom),2018,vol.54,#86,p.12182-12185

Downstream Synthesis Route

[1]TetrahedronLetters,2014,vol.55,p.1585-1588

[2]ChemCatChem,2017,vol.9,p.728-732

[3]NipponKagakuZasshi,1958,vol.79,p.1428,1430    Chem.Abstr.,1960,p.5518

[4]JournalofOrganicChemistry,2015,vol.80,p.10769-10776

[5]GreenChemistry,2017,vol.19,p.474-480

[6]Patent:CN110002961,2019,A.Locationinpatent:Paragraph0053-0055

[1]TetrahedronLetters,2006,vol.47,p.5705-5708

[2]Patent:US2007/276168,2007,A1.Locationinpatent:Page/Pagecolumn8

[3]JournaloftheChemicalSociety,1935,p.1167,1172

[4]JournaloftheAmericanChemicalSociety,1963,vol.85,p.709-724

[1]JournalofHeterocyclicChemistry,1992,vol.29,p.1753-1756

40137-11-9    455-36-7   
1-Fluoro-3-(1-methanesulfonylmethyl-vinyl)-benzene 
 
1-Fluoro-3-((Z)-2-methanesulfonyl-1-methyl-vinyl)-benzene 
 
1-Fluoro-3-((E)-2-methanesulfonyl-1-methyl-vinyl)-benzene 

[1]SyntheticCommunications,1994,vol.24,p.3225-3233

[1]Chai,Huining;Liu,Tingting;Zheng,Daoyuan;Yu,Zhengkun[Organometallics,2017,vol.36,#21,p.4268-4277]

[2]Topf,Christoph;Vielhaber,Thomas[AppliedCatalysisA:General,2021,vol.623]

[3]Shi,Jing;Hu,Bowen;Gong,Dawei;Shang,Shu;Hou,Guangfeng;Chen,Dafa[DaltonTransactions,2016,vol.45,#11,p.4828-4834]

[4]Shi,Jing;Shang,Shu;Hu,Bowen;Chen,Dafa[AppliedOrganometallicChemistry,2018,vol.32,#2]

[5]Han,Xingyou;Li,Feng;Liu,Peng;Wang,Rongzhou;Xu,Jing[JournalofOrganicChemistry,2020,vol.85,#4,p.2242-2249]

[6]Li,Ke;Niu,Jun-Long;Yang,Ming-Ze;Li,Zhen;Wu,Li-Yuan;Hao,Xin-Qi;Song,Mao-Ping[Organometallics,2015,vol.34,#7,p.1170-1176]

[7]Chen,Tao;Liu,Xu-Guang;Shi,Min[Tetrahedron,2007,vol.63,#23,p.4874-4880]

[8]Liu,Jiahao;Li,Weikang;Li,Yinwu;Liu,Yan;Ke,Zhuofeng[Chemistry-AnAsianJournal,2021,vol.16,#20,p.3124-3128]

[9]Peng,Dongjie;Zhang,Mintao;Huang,Zheng[Chemistry-AEuropeanJournal,2015,vol.21,#42,p.14737-14741]

[10]Doussot,Joel;Guy,Alain;Garreau,Robert;Falguieres,Annie;Cossy,Janine;Amsterdamsky,Claude[BulletindelaSocieteChimiquedeFrance,1996,vol.133,#2,p.161-166]

[11]Comasseto,JoaoV.;Omori,AlvaroT.;Andrade,LeandroH.;Porto,AndreL.M.[TetrahedronAsymmetry,2003,vol.14,#6,p.710-716]

[12]Groeger,Harald;Rollmann,Claudia;Chamouleau,Francoise;Sebastien,Isabelle;May,Oliver;Wienand,Wolfgang;Drauz,Karlheinz[AdvancedSynthesisandCatalysis,2007,vol.349,#4-5,p.709-712]

[13]Kurbanoglu,EsabiB.;Zilbeyaz,Kani;Kurbanoglu,NamudarI.;Kilic,Hamdullah[TetrahedronAsymmetry,2007,vol.18,#19,p.2332-2335]

[14]Locationinpatent:experimentalpartAndrade,LeandroH.;Piovan,Leandro;Pasquini,MonicaD.[TetrahedronAsymmetry,2009,vol.20,#13,p.1521-1525]

[15]Locationinpatent:experimentalpartKohtani,Shigeru;Yoshioka,Eito;Saito,Kenji;Kudo,Akihiko;Miyabe,Hideto[CatalysisCommunications,2010,vol.11,#13,p.1049-1053]

[16]Locationinpatent:experimentalpartLee,JaeKwan;Kim,Mahn-Joo[TetrahedronLetters,2011,vol.52,#4,p.499-501]

[17]Locationinpatent:bodytextKurbanoglu,EsabiB.;Zilbeyaz,Kani;Kurbanoglu,NamudarI.[TetrahedronAsymmetry,2011,vol.22,#3,p.345-350]

[18]Locationinpatent:experimentalpartSingh,Manpreet;Singh,RamSarup;Banerjee,UttamChand[ProcessBiochemistry,2010,vol.45,#1,p.25-29]

[19]Du,Wangming;Wu,Ping;Wang,Qingfu;Yu,Zhengkun[Organometallics,2013,vol.32,#10,p.3083-3090]

[20]Kohtani,Shigeru;Nishioka,Saki;Yoshioka,Eito;Miyabe,Hideto[CatalysisCommunications,2014,vol.43,p.61-65]

[21]Du,Wangming;Wang,Qingfu;Wang,Liandi;Yu,Zhengkun[Organometallics,2014,vol.33,#4,p.974-982]

[22]Kohtani,Shigeru;Kamoi,Yuna;Yoshioka,Eito;Miyabe,Hideto[Catalysisscienceandtechnology,2014,vol.4,#4,p.1084-1091]

[23]Chai,Huining;Liu,Tingting;Wang,Qingfu;Yu,Zhengkun[Organometallics,2015,vol.34,#21,p.5278-5284]

[24]Chai,Huining;Wang,Qingfu;Liu,Tingting;Yu,Zhengkun[DaltonTransactions,2016,vol.45,#44,p.17843-17849]

[25]Martínez-Montero,Lía;Gotor,Vicente;Gotor-Fernández,Vicente;Lavandera,Iván[GreenChemistry,2017,vol.19,#2,p.474-480]

[26]Wang,Qingfu;Chai,Huining;Yu,Zhengkun[Organometallics,2017,vol.36,#18,p.3638-3644]

[27]Liu,Tingting;Chai,Huining;Wang,Liandi;Yu,Zhengkun[Organometallics,2017,vol.36,#15,p.2914-2921]

[28]Alsafadi,Diya;Alsalman,Safaa;Paradisi,Francesca[OrganicandBiomolecularChemistry,2017,vol.15,#43,p.9169-9175]

[29]Liu,Sensheng;Liu,Huan;Zhou,Haifeng;Liu,Qixing;Lv,Jinliang[OrganicLetters,2018,vol.20,#4,p.1110-1113]

[30]Yan,Dandan;Dai,Ping;Chen,Sufang;Xue,Mingqiang;Yao,Yingming;Shen,Qi;Bao,Xiaoguang[OrganicandBiomolecularChemistry,2018,vol.16,#15,p.2787-2791]

[31]Liu,Yaxu;He,Shaopo;Quan,Ziyi;Cai,Huizhuo;Zhao,Yang;Wang,Bo[GreenChemistry,2019,vol.21,#4,p.830-838]

[32]Salome,KahlilSchwanka;Tormena,ClaúdioFrancisco[ChemicalCommunications,2019,vol.55,#59,p.8611-8614]

[33]Liu,Tingting;Wu,Kaikai;Wang,Liandi;Fan,Hongjun;Zhou,Yong-Gui;Yu,Zhengkun[Organometallics,2020,vol.39,#1,p.93-104]

[34]Choudhary,Neha;Ghosh,Topi;Mobin,ShaikhM.[Chemistry-AnAsianJournal,2020,vol.15,#8,p.1339-1348]

[35]Yuan,Bo;Debecker,DamienP.;Wu,Xiaofeng;Xiao,Jianliang;Fei,Qiang;Turner,NicholasJ.[ChemCatChem,2020,vol.12,#24,p.6191-6195]

[36]Faust,Kirill;Topf,Christoph;Vielhaber,Thomas[Organometallics,2020,vol.39,#24,p.4535-4543]

[37]Jia,Wei-Guo;Zhi,Xue-Ting;Li,Xiao-Dong;Zhou,Jun-Peng;Zhong,Rui;Yu,Haibo;Lee,Richmond[InorganicChemistry,2021,vol.60,#7,p.4313-4321]

[38]Li,Rong-Jian;Wang,Yang;Jin,Yan;Deng,Wei;Liu,Zhen-Jiang;Yao,Zi-Jian[NewJournalofChemistry,2021,vol.45,#40,p.19002-19010]

Literature

Title: Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.

Journal: ChemMedChem 20120102

Title: N'-[(E)-1-(3-Fluoro-phen-yl)ethyl-idene]formohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

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Tags:455-36-7 Molecular Formula|455-36-7 MDL|455-36-7 SMILES|455-36-7 3'-Fluoroacetophenone |Fluorinated_Building_Blocks |Halogenated_Heterocycles