Home Fluorides 456-22-4
456-22-4,MFCD00002530
Catalog No.:AA0033YL

456-22-4 | 4-Fluorobenzoic acid

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25g
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0033YL
Chemical Name:
4-Fluorobenzoic acid
CAS Number:
456-22-4
Molecular Formula:
C7H5FO2
Molecular Weight:
140.1118
MDL Number:
MFCD00002530
SMILES:
OC(=O)c1ccc(cc1)F
NSC Number:
10321
Properties
Properties
 
BP:
253.7°C at 760 mmHg  
Form:
Solid  
MP:
184 °C  
Solubility:
alcohol: soluble  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
128  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.1  

Literature

Title: Preclinical characterization of 18F-MAA, a novel PET surrogate of 99mTc-MAA.

Journal: Nuclear medicine and biology 20121001

Title: Isolation and characterization of a Rhodococcus strain able to degrade 2-fluorophenol.

Journal: Applied microbiology and biotechnology 20120701

Title: 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 4-fluoro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: Biodegradation kinetics of 4-fluorocinnamic acid by a consortium of Arthrobacter and Ralstonia strains.

Journal: Biodegradation 20120201

Title: Aqua-bis-(4-fluoro-benzoato-κO)bis-(nicotinamide-κN)copper(II) nicotinamide hemisolvate trihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazone derivatives containing a pyridine moiety.

Journal: Chemistry Central journal 20120101

Title: Aqua-(4-fluoro-benzoato-κO)bis-(1,10-phenanthroline-κN,N')manganese(II) 4-fluoro-benzoate trihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Extending the supramolecular synthon based fragment approach (SBFA) for transferability of multipole charge density parameters to monofluorobenzoic acids and their cocrystals with isonicotinamide: importance of C-H···O, C-H···F, and F···F intermolecular regions.

Journal: The journal of physical chemistry. A 20111117

Title: trans-Diaqua-bis-(4-fluoro-benzoato-κO)bis-(nicotinamide-κN)nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Computational prediction of salt and cocrystal structures--does a proton position matter?

Journal: International journal of pharmaceutics 20111014

Title: Synthesis, biological activity and HPLC validation of 1,2,3,4-tetrahydroacridine derivatives as acetylcholinesterase inhibitors.

Journal: European journal of medicinal chemistry 20110801

Title: Diaqua-bis-(N,N'-diethyl-nicotinamide-κN)bis-(4-fluoro-benzoato-κO)copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Biodegradation of polyfluorinated biphenyl in bacteria.

Journal: Biodegradation 20110701

Title: Poly[[diaqua-manganese(II)]-bis-(μ-4-fluoro-benzoato-κO:O')].

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Bis-(4-fluoro-benzoato)-κO,O';κO-(4-fluoro-benzoic acid-κO)bis-(nico-tinamide-κN)copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer.

Journal: Nuclear medicine and biology 20110501

Title: Factors influencing 4-fluorobenzoate degradation in biofilm cultures of Pseudomonas knackmussii B13.

Journal: Water research 20110501

Title: Seven hexamethylenetetramine (HMTA) complexes with mono- and dicarboxylic acids: analysis of packing modes of HMTA complexes in the literature.

Journal: Acta crystallographica. Section B, Structural science 20110401

Title: Tuning of the ionization potential of paddlewheel diruthenium(II, II) complexes with fluorine atoms on the benzoate ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20110121

Title: Tetra-aqua-(2,2'-bipyridine-κN,N')magnesium(II) bis-(4-fluoro-benzoate).

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Trichodermin (12,13-ep-oxy-trichethec-9-en-4β-yl 4-fluoro-benzoate).

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Looking for a 5-HT7 radiotracer for positron emission tomography.

Journal: Bioorganic & medicinal chemistry letters 20100615

Title: (2,7-Dimethoxy-naphthalene-1,8-di-yl)bis-(4-fluoro-benzo-yl)dimethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20100201

Title: The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader.

Journal: PloS one 20100101

Title: Proteome analysis of soybean leaves, hypocotyls and roots under salt stress.

Journal: Proteome science 20100101

Title: Genuine genetic redundancy in maleylacetate-reductase-encoding genes involved in degradation of haloaromatic compounds by Cupriavidus necator JMP134.

Journal: Microbiology (Reading, England) 20091101

Title: Identification and simultaneous determination of p-FHA and p-FBA, two metabolites of anti-tumor agent--Fluorapacin in rat urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090515

Title: catena-Poly[[diaqua-cobalt(II)]-bis-(μ-4-fluoro-benzoato-κO:O')].

Journal: Acta crystallographica. Section E, Structure reports online 20090501

Title: Arabidopsis GH3.12 (PBS3) conjugates amino acids to 4-substituted benzoates and is inhibited by salicylate.

Journal: The Journal of biological chemistry 20090410

Title: 4-Hydroxy-phenyl 4-fluoro-benzoate.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabeling agents of PEPHC1 for PET imaging of EGFRvIII.

Journal: Advances in experimental medicine and biology 20090101

Title: Vibrational spectroscopic studies and ab initio calculations of 5-nitro-2-(p-fluorophenyl)benzoxazole.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081115

Title: Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenes KF707.

Journal: FEMS microbiology letters 20080901

Title: Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

Journal: Molecular pharmacology 20080801

Title: Prodrugs of fluoro-substituted benzoates of EGC as tumor cellular proteasome inhibitors and apoptosis inducers.

Journal: International journal of molecular sciences 20080601

Title: trans-Diaqua-bis(ethyl-enediamine-κN,N')copper(II) bis[3-(3-pyrid-yl)propionate] dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080401

Title: Degradation of 4-fluorophenol by Arthrobacter sp. strain IF1.

Journal: Applied microbiology and biotechnology 20080301

Title: Bis(4-fluoro-benzoato-κO,O')bis-(nicotinamide-κN)zinc(II) monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080301

Title: Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU).

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070201

Title: Second-sphere coordination in anion binding: sodium hexaamminecobalt(III) tetrakis(4-fluorobenzoate) monohydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20050701

Title: Isolation and properties of a pure bacterial strain capable of fluorobenzene degradation as sole carbon and energy source.

Journal: Environmental microbiology 20050201

Title: Inhibitory effects of 4-halobenzoic acids on the diphenolase and monophenolase activity of mushroom tyrosinase.

Journal: The protein journal 20040701

Title: Characterization of a gene cluster encoding the maleylacetate reductase from Ralstonia eutropha 335T, an enzyme recruited for growth with 4-fluorobenzoate.

Journal: Microbiology (Reading, England) 20040201

Title: Non-invasive 19F MR spectroscopy of 5-fluorocytosine to 5-fluorouracil conversion by recombinant Salmonella in tumours.

Journal: British journal of cancer 20031103

Title: Brain uptake of the acid metabolites of F-18-labeled WAY 100635 analogs.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030201

Title: Raman evidence for Meisenheimer complex formation in the hydrolysis reactions of 4-fluorobenzoyl- and 4-nitrobenzoyl-coenzyme A catalyzed by 4-chlorobenzoyl-coenzyme A dehalogenase.

Journal: Biochemistry 20020611

Title: Fluorine-18 labeled mouse bone marrow-derived dendritic cells can be detected in vivo by high resolution projection imaging.

Journal: Journal of immunological methods 20020201

Title: Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines.

Journal: Farmaco (Societa chimica italiana : 1989) 20020201

Title: Aerobic biotransformation of 4-fluorocinnamic acid to 4-fluorobenzoic acid.

Journal: Biodegradation 20010101

Title: [Effect of human serum albumin on transport of drugs through human erythrocyte membranes].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 19960801

Title: NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

Journal: Journal of bacteriology 19960501

Title: Different types of dienelactone hydrolase in 4-fluorobenzoate-utilizing bacteria.

Journal: Journal of bacteriology 19900901

Title: Enzymatic formation, stability, and spontaneous reactions of 4-fluoromuconolactone, a metabolite of the bacterial degradation of 4-fluorobenzoate.

Journal: Journal of bacteriology 19900901

Title: Evidence for a new pathway in the bacterial degradation of 4-fluorobenzoate.

Journal: Applied and environmental microbiology 19891001

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