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4562-36-1,MFCD00021173
Catalog No.:AA006ZFM

4562-36-1 | Gitoxin

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5mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006ZFM
Chemical Name:
Gitoxin
CAS Number:
4562-36-1
Molecular Formula:
C40H61O14
Molecular Weight:
765.9039
MDL Number:
MFCD00021173
SMILES:
O=C1OCC(=C1)[C@H]1[C@@H](O)C[C@]2([C@]1(C)CC[C@H]1[C@H]2CC[C@H]2[C@]1(C)CC[C@@H](C2)O[C@H]1C[C@H](O)[C@@H]([C@H](O1)C)O[C@H]1C[C@H](O)[C@@H]([C@H](O1)C)O[C@@H]1O[CH][C@H]([C@H](C1)O)O)O
Properties
Computed Properties
 
Complexity:
1450  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
21  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
7  
XLogP3:
1.5  

Literature

Title: HPLC method validation for Digitalis and its analogue by pulsed amperometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: Simple coacervates of zein to encapsulate Gitoxin.

Journal: Colloids and surfaces. B, Biointerfaces 20060801

Title: Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients.

Journal: Journal of natural products 20051101

Title: Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase.

Journal: Journal of enzyme inhibition and medicinal chemistry 20041001

Title: Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii.

Journal: Planta medica 20030801

Title: Modifying specificity of antidigoxin antibodies using insertional mutagenesis.

Journal: Protein science : a publication of the Protein Society 20021201

Title: Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.

Journal: Journal of medicinal chemistry 20020718

Title: Complementary combining site contact residue mutations of the anti-digoxin Fab 26-10 permit high affinity wild-type binding.

Journal: The Journal of biological chemistry 20020510

Title: A single H:CDR3 residue in the anti-digoxin antibody 26-10 modulates specificity for C16-substituted digoxin analogs.

Journal: Protein engineering 20010401

Title: Phage display-selected sequences of the heavy-chain CDR3 loop of the anti-digoxin antibody 26-10 define a high affinity binding site for position 16-substituted analogs of digoxin.

Journal: The Journal of biological chemistry 20010316

Title: Structure and specificity of the anti-digoxin antibody 40-50.

Journal: Journal of molecular biology 19950428

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Tags:4562-36-1 Molecular Formula|4562-36-1 MDL|4562-36-1 SMILES|4562-36-1 Gitoxin