Home Iodos 4604-41-5
4604-41-5,MFCD01863378
Catalog No.:AA00329K

4604-41-5 | 3,3'-Diiodo-l-thyronine

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100mg
95%
in stock  
$68.00   $48.00
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1g
95%
in stock  
$399.00   $280.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00329K
Chemical Name:
3,3'-Diiodo-l-thyronine
CAS Number:
4604-41-5
Molecular Formula:
C15H13I2NO4
Molecular Weight:
525.0770
MDL Number:
MFCD01863378
SMILES:
OC(=O)[C@H](Cc1ccc(c(c1)I)Oc1ccc(c(c1)I)O)N
Properties
Properties
 
BP:
520.7°C at 760 mmHg  
Form:
Solid  
MP:
178-180°C  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
385  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
1.1  

Literature

Title: Analysis of thyroid hormones in serum of Baikal seals and humans by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and immunoassay methods: application of the LC-MS/MS method to wildlife tissues.

Journal: Environmental science & technology 20111201

Title: Modulation of thyroid hormone concentrations in serum of rats coadministered with perchlorate and iodide-deficient diet.

Journal: Archives of environmental contamination and toxicology 20110701

Title: Determination of six thyroid hormones in the brain and thyroid gland using isotope-dilution liquid chromatography/tandem mass spectrometry.

Journal: Analytical chemistry 20110101

Title: Primary and secondary thyroid hormone transporters.

Journal: Thyroid research 20110101

Title: A method for the analysis of six thyroid hormones in thyroid gland by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701

Title: Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism.

Journal: Molecular endocrinology (Baltimore, Md.) 20061101

Title: The role of thyroid hormone therapy in acutely ill cardiac patients.

Journal: Critical care (London, England) 20050101

Title: Measurement of 3,3'-diiodothyronine sulfate (T2S) in thyroidal and nonthyroidal disease, pregnancy, and fetal/neonatal life.

Journal: Metabolism: clinical and experimental 20041001

Title: Inhibition of the activity of the native gamma-aminobutyric acid A receptor by metabolites of thyroid hormones: correlations with molecular modeling studies.

Journal: Brain research 20040409

Title: A radioimmunoassay for measurement of 3,3'-diiodothyronine sulfate: Studies in thyroidal and nonthyroidal diseases, pregnancy, and fetal/neonatal life.

Journal: Metabolism: clinical and experimental 20040401

Title: Comparative evaluation of 11 scoring functions for molecular docking.

Journal: Journal of medicinal chemistry 20030605

Title: Uptake of triiodothyronine and triiodothyroacetic acid in neonatal rat cardiomyocytes: effects of metabolites and analogs.

Journal: The Journal of endocrinology 20020501

Title: Characterization of iodothyronine sulfatase activities in human and rat liver and placenta.

Journal: Endocrinology 20020301

Title: Characterization of uptake and compartmentalization of 3,5,3'-tri-iodothyronine in cultured neonatal rat cardiomyocytes.

Journal: The Journal of endocrinology 20011001

Title: 3,3'-Diiodothyronine sulfate excretion in maternal urine reflects fetal thyroid function in sheep.

Journal: Pediatric research 20010901

Title: Molecular cloning, expression, and characterization of a canine sulfotransferase that is a human ST1B2 ortholog.

Journal: Archives of biochemistry and biophysics 20010601

Title: Sulfation of thyroid hormone and dopamine during human development: ontogeny of phenol sulfotransferases and arylsulfatase in liver, lung, and brain.

Journal: The Journal of clinical endocrinology and metabolism 20010601

Title: Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88.

Title: Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb;99(1):89-94.

Title: Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun;32(6):e4185.

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Tags:4604-41-5 Molecular Formula|4604-41-5 MDL|4604-41-5 SMILES|4604-41-5 3,3'-Diiodo-l-thyronine