Title: Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors.
Journal: Chemico-biological interactions 20180325
Title: Intrinsic capabilities of Leptospermum javanicum in inducing apoptosis and suppressing the metastatic potential of human lung carcinoma cells.
Journal: Chemico-biological interactions 20170801
Title: Biological evaluation of a halogenated triterpenoid, 2α-bromo-dihydrobelulonic acid as inhibitor of human topoisomerase IIα and HeLa cell proliferation.
Journal: Chemico-biological interactions 20170425
Title: In vitro anticancer activity of Betulinic acid and derivatives thereof on equine melanoma cell lines from grey horses and in vivo safety assessment of the compound NVX-207 in two horses.
Journal: Chemico-biological interactions 20160225
Title: Fluorinated betulinic acid derivatives and evaluation of their anti-HIV activity.
Journal: Bioorganic & medicinal chemistry letters 20160101
Title: Betulinyl Sulfamates as Anticancer Agents and Radiosensitizers in Human Breast Cancer Cells.
Journal: International journal of molecular sciences 20151101
Title: Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Journal: Bioorganic & medicinal chemistry letters 20150815
Title: Combined effect of microRNA, nutraceuticals and drug on pancreatic cancer cell lines.
Journal: Chemico-biological interactions 20150525
Title: Synthesis and anti-HCV entry activity studies of β-cyclodextrin-pentacyclic triterpene conjugates.
Journal: ChemMedChem 20140501
Title: Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment.
Journal: Toxicology and applied pharmacology 20140301
Title: Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities.
Journal: Pathogens and disease 20130801
Title: Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.
Journal: Journal of medicinal chemistry 20130613
Title: Synthesis and biological evaluation of a new derivative of bevirimat that targets the Gag CA-SP1 cleavage site.
Journal: European journal of medicinal chemistry 20130401
Title: Quantitative purity-activity relationships of natural products: the case of anti-tuberculosis active triterpenes from Oplopanax horridus.
Journal: Journal of natural products 20130322
Title: GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death.
Journal: Cancer letters 20130201
Title: A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.
Journal: Food chemistry 20130115
Title: Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L.
Journal: Food chemistry 20130115
Title: A novel one-step microbial transformation of betulin to betulinic acid catalysed by Cunninghamella blakesleeana.
Journal: Food chemistry 20130101
Title: Phytochemical profile of Rosmarinus officinalis and Salvia officinalis extracts and correlation to their antioxidant and anti-proliferative activity.
Journal: Food chemistry 20130101
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus.
Journal: Planta 20121101
Title: Antimycobacterial assessment of Salicylanilide benzoates including multidrug-resistant tuberculosis strains.
Journal: Molecules (Basel, Switzerland) 20121031
Title: Bioactive oleanane, lupane and ursane triterpene acid derivatives.
Journal: Molecules (Basel, Switzerland) 20121017
Title: Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana.
Journal: Bioorganic & medicinal chemistry letters 20121015
Title: Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.
Journal: Molecules (Basel, Switzerland) 20121012
Title: Ionic derivatives of betulinic acid as novel HIV-1 protease inhibitors.
Journal: Journal of enzyme inhibition and medicinal chemistry 20121001
Title: A novel triterpene extract from mistletoe induces rapid apoptosis in murine B16.F10 melanoma cells.
Journal: Phytotherapy research : PTR 20121001
Title: Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid-induced bicarbonate secretion in rat duodenum.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20121001
Title: Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120929
Title: Anti-AIDS agents 90. novel C-28 modified bevirimat analogues as potent HIV maturation inhibitors.
Journal: Journal of medicinal chemistry 20120927
Title: Mesua beccariana (Clusiaceae), a source of potential anti-cancer lead compounds in drug discovery.
Journal: Molecules (Basel, Switzerland) 20120910
Title: Investigation of the interactions of lupane type pentacyclic triterpenes with outer leaflet membrane phospholipids--Langmuir monolayer and synchrotron X-ray scattering study.
Journal: Journal of colloid and interface science 20120901
Title: Hepatoprotective potential of Tecomella undulata stem bark is partially due to the presence of betulinic acid.
Journal: Journal of ethnopharmacology 20120830
Title: Synthesis of betulinic acid derivatives as entry inhibitors against HIV-1 and bevirimat-resistant HIV-1 variants.
Journal: Bioorganic & medicinal chemistry letters 20120815
Title: Triterpene acids from rose hip powder inhibit self-antigen- and LPS-induced cytokine production and CD4⁺ T-cell proliferation in human mononuclear cell cultures.
Journal: Phytotherapy research : PTR 20120801
Title: Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.
Journal: Cell death and differentiation 20120801
Title: Betulinic acid exerts immunoregulation and anti-tumor effect on cervical carcinoma (U14) tumor-bearing mice.
Journal: Die Pharmazie 20120801
Title: Betulin as an antitumor agent tested in vitro on A431, HeLa and MCF7, and as an angiogenic inhibitor in vivo in the CAM assay.
Journal: Natural product communications 20120801
Title: Exploration of the antiplatelet activity profile of betulinic acid on human platelets.
Journal: Journal of agricultural and food chemistry 20120718
Title: Synthesis and cytotoxicity of lupane-type triterpenoid glyceryl esters.
Journal: Bioorganic & medicinal chemistry letters 20120715
Title: Antiparasitic compounds from Cornus florida L. with activities against Plasmodium falciparum and Leishmania tarentolae.
Journal: Journal of ethnopharmacology 20120713
Title: Betulinic acid has an inhibitory effect on pancreatic lipase and induces adipocyte lipolysis.
Journal: Phytotherapy research : PTR 20120701
Title: Betulinic acid targets YY1 and ErbB2 through cannabinoid receptor-dependent disruption of microRNA-27a:ZBTB10 in breast cancer.
Journal: Molecular cancer therapeutics 20120701
Title: [Chemical constituents contained in Macropanax rosthornii].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701
Title: Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Molecular dynamics simulation studies of betulinic acid with human serum albumin.
Journal: Journal of molecular modeling 20120601
Title: Effect on tumor necrosis factor-α production and antioxidant ability of black alder, as factors related to its anti-inflammatory properties.
Journal: Journal of medicinal food 20120601
Title: Orthoquinone and naphthalenone derivatives from Berrya ammonilla and their anti-inflammatory activity.
Journal: Planta medica 20120601
Title: Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.
Journal: Bioorganic & medicinal chemistry 20120601
Title: NOXA as critical mediator for drug combinations in polychemotherapy.
Journal: Cell death & disease 20120601
Title: Betulinic acid induces Bax/Bak-independent cytochrome c release in human nasopharyngeal carcinoma cells.
Journal: Molecules and cells 20120531
Title: Effect of betulinic acid on neutrophil recruitment and inflammatory mediator expression in lipopolysaccharide-induced lung inflammation in rats.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120512
Title: Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7.
Journal: Chest 20120501
Title: [Chemical constituents of Dolomiaea souliei].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501
Title: Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
Journal: Journal of natural products 20120427
Title: Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi.
Journal: Journal of natural products 20120427
Title: Synthesis and biological evaluation of heterocyclic ring-fused betulinic acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption.
Journal: Journal of medicinal chemistry 20120412
Title: Preliminary study of the anticancer applications of mesoporous materials functionalized with the natural product betulinic acid.
Journal: ChemMedChem 20120401
Title: Rapid separation and determination of betulinic acid from a complex matrix using combination of TLC and RP-HPLC.
Journal: Pakistan journal of pharmaceutical sciences 20120401
Title: Arsenite-induced apoptosis of human neuroblastoma cells requires p53 but occurs independently of c-Jun.
Journal: Neuroscience 20120329
Title: Lupane-type pentacyclic triterpenes in Langmuir monolayers: a synchrotron radiation scattering study.
Journal: Langmuir : the ACS journal of surfaces and colloids 20120320
Title: alpha-Mangostin enhances betulinic acid cytotoxicity and inhibits cisplatin cytotoxicity on HCT 116 colorectal carcinoma cells.
Journal: Molecules (Basel, Switzerland) 20120308
Title: A comparison investigation on the solubilization of betulin and betulinic acid in cyclodextrin derivatives.
Journal: Natural product communications 20120301
Title: New ionic derivatives of betulinic acid as highly potent anti-cancer agents.
Journal: Bioorganic & medicinal chemistry letters 20120215
Title: The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation.
Journal: Chemico-biological interactions 20120205
Title: Does NAD(P)H oxidase-derived H2O2 participate in hypotonicity-induced insulin release by activating VRAC in β-cells?
Journal: Pflugers Archiv : European journal of physiology 20120201
Title: [Study on absorption kinetics of betulic acid in rat's intestines].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120201
Title: The natural product betulinic acid inhibits C/EBP family transcription factors.
Journal: Chembiochem : a European journal of chemical biology 20120123
Title: Physico-chemical comparison of betulinic acid, betulin and birch bark extract and in vitro investigation of their cytotoxic effects towards skin epidermoid carcinoma (A431), breast carcinoma (MCF7) and cervix adenocarcinoma (HeLa) cell lines.
Journal: Natural product research 20120101
Title: Bioguided isolation of pentacyclic triterpenes from the leaves of Alstonia scholaris (Linn.) R. Br. growing in Egypt.
Journal: Natural product research 20120101
Title: A new triterpene from Barringtonia asiatica.
Journal: Natural product research 20120101
Title: A new fatty aldol ester from the aerial part of Mimosa invisa (Mimosaceae).
Journal: Natural product research 20120101
Title: Synthesis of bioactive 28-hydroxy-3-oxolup-20(29)-en-30-al with antileukemic activity.
Journal: Journal of Asian natural products research 20120101
Title: Bioactivity Evaluation of Plant Extracts Used in Indigenous Medicine against the Snail, Biomphalaria glabrata, and the Larvae of Aedes aegypti.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Melastoma malabathricum (L.) Smith Ethnomedicinal Uses, Chemical Constituents, and Pharmacological Properties: A Review.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein.
Journal: Retrovirology 20120101
Title: Antiproliferative property of n-hexane and chloroform extracts of Anisomeles malabarica (L). R. Br. in HPV16-positive human cervical cancer cells.
Journal: Journal of pharmacology & pharmacotherapeutics 20120101
Title: New galloyl derivative from winged sumac (Rhus copallinum) fruit.
Journal: Natural product communications 20120101
Title: Triterpenes from Callicarpa integerrima Champ.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120101
Title: Ethanolic Extract of Vitis thunbergii Exhibits Lipid Lowering Properties via Modulation of the AMPK-ACC Pathway in Hypercholesterolemic Rabbits.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.
Journal: PloS one 20120101
Title: Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer.
Journal: PloS one 20120101
Title: Notch, wnt, and hedgehog pathways in rhabdomyosarcoma: from single pathways to an integrated network.
Journal: Sarcoma 20120101
Title: Mitochondria: redox metabolism and dysfunction.
Journal: Biochemistry research international 20120101
Title: Antinociceptive, anti-inflammatory, and antipyretic activity of mangrove plants: a mini review.
Journal: Advances in pharmacological sciences 20120101
Title: Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo.
Journal: PloS one 20120101
Title: Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Radiation, inflammation, and immune responses in cancer.
Journal: Frontiers in oncology 20120101
Title: Antimicrobial Constituents of Artemisia afra Jacq. ex Willd. against Periodontal Pathogens.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Influence of betulinic acid on lymphocyte subsets and humoral immune response in mice.
Journal: Polish journal of veterinary sciences 20120101
Title: Lignans and triterpenes from the root of Pseuderanthemum carruthersii var. atropurpureum.
Journal: Chemical & pharmaceutical bulletin 20120101
Title: Betulinic Acid inhibits growth of cultured vascular smooth muscle cells in vitro by inducing g(1) arrest and apoptosis.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Betulinic acid inhibits superoxide anion-mediated impairment of endothelium-dependent relaxation in rat aortas.
Journal: Indian journal of pharmacology 20120101
Title: A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii.
Journal: Fitoterapia 20111201
Title: Low molecular weight heparin downregulates tissue factor expression and activity by modulating growth factor receptor-mediated induction of nuclear factor-κB.
Journal: Biochimica et biophysica acta 20111201
Title: CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.
Journal: Plant & cell physiology 20111201
Title: Antifungal metabolites from the roots of Diospyros virginiana by overpressure layer chromatography.
Journal: Chemistry & biodiversity 20111201
Title: First self-assembly study of betulinic acid, a renewable nano-sized, 6-6-6-6-5 pentacyclic monohydroxy triterpenic acid.
Journal: Nanoscale 20111101
Title: Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii.
Journal: Journal of natural products 20111028
Title: Two new xanthones from Calophyllum nodusum (Guttiferae).
Journal: Molecules (Basel, Switzerland) 20111025
Title: Efficient synthesis of lupane-type saponins via gold(I)-catalyzed glycosylation with glycosyl ortho-alkynylbenzoates as donors.
Journal: Organic letters 20111021
Title: Betulinic acid ameliorates endothelium-dependent relaxation in L-NAME-induced hypertensive rats by reducing oxidative stress.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111009
Title: Co-treatment with ginsenoside Rh2 and betulinic acid synergistically induces apoptosis in human cancer cells in association with enhanced capsase-8 activation, bax translocation, and cytochrome c release.
Journal: Molecular carcinogenesis 20111001
Title: New betulinic acid derivatives as potent proteasome inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: A new furanoxanthone from the stem bark of Calophyllum inophyllum.
Journal: Journal of Asian natural products research 20111001
Title: In vitro effect of combined hybrid molecules from vitamin E analogues and betulinic acid on macrophage activity.
Journal: Bulletin of experimental biology and medicine 20111001
Title: Simultaneous qualitative and quantitative analysis of triterpenic acids, saponins and flavonoids in the leaves of two Ziziphus species by HPLC-PDA-MS/ELSD.
Journal: Journal of pharmaceutical and biomedical analysis 20110910
Title: An amphiphilic conjugate approach toward the design and synthesis of betulinic acid-polyphenol conjugates as inhibitors of the HIV-1 gp41 fusion core formation.
Journal: ChemMedChem 20110905
Title: Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling.
Journal: British journal of pharmacology 20110901
Title: Targeting Sp1 transcription factors in prostate cancer therapy.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20110901
Title: Identification and determination of carboxylic acids in food samples using 2-(2-(anthracen-10-yl)-1H-phenanthro[9,10-d]imidazol-1-yl)ethyl 4-methylbenzenesulfonate (APIETS) as labeling reagent by HPLC with FLD and APCI/MS.
Journal: Talanta 20110815
Title: Sp1 inhibition-mediated upregulation of VEGF 165 b induced by rh-endostatin enhances antiangiogenic and anticancer effect of rh-endostatin in A549.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110801
Title: Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis.
Journal: Cancer research 20110801
Title: Improvement of the cytotoxicity and tumor selectivity of glycyrrhetinic acid by derivatization with bifunctional amino acids.
Journal: Archiv der Pharmazie 20110801
Title: Up-regulation of cyclooxygenase-2-derived prostaglandin E(2) in colon cancer cells resistant to 5-fluorouracil.
Journal: Journal of the Korean Surgical Society 20110801
Title: [Study on the chemical constituents of Leptopus chineseis].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110801
Title: Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells.
Journal: Molecules (Basel, Switzerland) 20110719
Title: Birch bark extract as therapy for chronic hepatitis C--a pilot study.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110715
Title: Understanding the structure-activity relationship of betulinic acid derivatives as anti-HIV-1 agents by using 3D-QSAR and docking.
Journal: Journal of molecular modeling 20110701
Title: A single polymorphism in HIV-1 subtype C SP1 is sufficient to confer natural resistance to the maturation inhibitor bevirimat.
Journal: Antimicrobial agents and chemotherapy 20110701
Title: Novel 3-oxo- and 3,24-dinor-2,4-secooleanane-type triterpenes from Terminalia ivorensis A. Chev.
Journal: Chemistry & biodiversity 20110701
Title: Constituents of the root of Anemone tomentosa.
Journal: Archives of pharmacal research 20110701
Title: New betulinic acid derivatives induce potent and selective antiproliferative activity through cell cycle arrest at the S phase and caspase dependent apoptosis in human cancer cells.
Journal: Biochimie 20110601
Title: Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
Journal: Journal of natural products 20110527
Title: Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress.
Journal: Nitric oxide : biology and chemistry 20110430
Title: Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.
Journal: Bioorganic & medicinal chemistry letters 20110415
Title: Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits.
Journal: Journal of agricultural and food chemistry 20110413
Title: Lupane triterpenoids--betulin and betulinic acid derivatives induce apoptosis in tumor cells.
Journal: Investigational new drugs 20110401
Title: Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms.
Journal: The Journal of pharmacy and pharmacology 20110401
Title: Antileukemic activity of the leaf extract of Bischofia javanica blume on human leukemic cell lines.
Journal: Indian journal of pharmacology 20110401
Title: Anti-angiogenic effects of betulinic acid administered in nanoemulsion formulation using chorioallantoic membrane assay.
Journal: Journal of biomedical nanotechnology 20110401
Title: Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E(2) production in human peripheral blood mononuclear cells.
Journal: British journal of pharmacology 20110301
Title: Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity.
Journal: Anti-cancer drugs 20110301
Title: Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.
Journal: Oncotarget 20110301
Title: Betulin and betulinic acid attenuate ethanol-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS), cytokine (TNF-α, TGF-β) production and by influencing intracellular signaling.
Journal: Toxicology 20110227
Title: Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.).
Journal: Phytotherapy research : PTR 20110201
Title: Anxiolytic activity of a supercritical carbon dioxide extract of Souroubea sympetala (Marcgraviaceae).
Journal: Phytotherapy research : PTR 20110201
Title: In vitro hepatoprotective and antioxidant activities of crude extract and isolated compounds from Ficus gnaphalocarpa.
Journal: Inflammopharmacology 20110201
Title: Effect of culture conditions on synthesis of triterpenoids in suspension cultures of Lantana camara L.
Journal: Bioprocess and biosystems engineering 20110101
Title: Biotransformation optimization of betulin into betulinic acid production catalysed by cultured Armillaria luteo-virens Sacc ZJUQH100-6 cells.
Journal: Journal of applied microbiology 20110101
Title: Monolayer behavior of binary systems of betulinic acid and cardiolipin: thermodynamic analyses of Langmuir monolayers and AFM study of Langmuir-Blodgett monolayers.
Journal: Journal of colloid and interface science 20110101
Title: Anti-inflammatory, immunomodulatory, and heme oxygenase-1 inhibitory activities of ravan napas, a formulation of uighur traditional medicine, in a rat model of allergic asthma.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Anticancer Potential of Aqueous Ethanol Seed Extract of Ziziphus mauritiana against Cancer Cell Lines and Ehrlich Ascites Carcinoma.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids.
Journal: Plant physiology 20110101
Title: Unexpected applications of secondary metabolites.
Journal: Biotechnology advances 20110101
Title: Synthesis, encapsulation and antitumor activity of new betulin derivatives.
Journal: Archiv der Pharmazie 20110101
Title: Antiapoptotic and Antioxidant Properties of Orthosiphon stamineus Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Phenylpropanoids from the stem bark of Jacaranda mimosaefolia.
Journal: Natural product research 20110101
Title: Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae).
Journal: BMC complementary and alternative medicine 20110101
Title: 3-O-(E)-p-coumaroyl tormentic acid from Eriobotrya japonica leaves induces caspase-dependent apoptotic cell death in human leukemia cell line.
Journal: Chemical & pharmaceutical bulletin 20110101
Title: Docking study of HIV-1 reverse transcriptase with phytochemicals.
Journal: Bioinformation 20110101
Title: Anti-inflammatory effects of seeds of the tropical fruit camu-camu (Myrciaria dubia).
Journal: Journal of nutritional science and vitaminology 20110101
Title: The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism.
Journal: BMC cancer 20110101
Title: Preparation of herbal tea as infusion or by maceration at room temperature using mistletoe tea as an example.
Journal: Scientia pharmaceutica 20110101
Title: Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction.
Journal: PloS one 20110101
Title: Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains.
Journal: Annals of clinical microbiology and antimicrobials 20110101
Title: Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark.
Journal: Malaria journal 20110101
Title: Anticancer activity of 2α, 3α, 19β, 23β-Tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid isolated from Sinojackia sarcocarpa.
Journal: PloS one 20110101
Title: Chemical analysis of Greek pollen - Antioxidant, antimicrobial and proteasome activation properties.
Journal: Chemistry Central journal 20110101
Title: Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells.
Journal: PloS one 20110101
Title: A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
Journal: BMC cancer 20110101
Title: Safety of higher dosages of Viscum album L. in animals and humans--systematic review of immune changes and safety parameters.
Journal: BMC complementary and alternative medicine 20110101
Title: Anti-inflammatory effects of Scoparia dulcis L. and betulinic acid.
Journal: The American journal of Chinese medicine 20110101
Title: Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions.
Journal: Radiation oncology (London, England) 20110101
Title: Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening.
Journal: Malaria journal 20110101
Title: Characterization of a novel type of HIV-1 particle assembly inhibitor using a quantitative luciferase-Vpr packaging-based assay.
Journal: PloS one 20110101
Title: Inhibitory effect of aqueous Dandelion extract on HIV-1 replication and reverse transcriptase activity.
Journal: BMC complementary and alternative medicine 20110101
Title: Nanoparticulate formulations of mithramycin analogs for enhanced cytotoxicity.
Journal: International journal of nanomedicine 20110101
Title: The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.
Journal: Retrovirology 20110101
Title: Morphogenesis of the Infectious HIV-1 Virion.
Journal: Frontiers in microbiology 20110101
Title: Antiplasmodial Properties and Bioassay-Guided Fractionation of Ethyl Acetate Extracts from Carica papaya Leaves.
Journal: Journal of parasitology research 20110101
Title: Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells.
Journal: Pharmacological reports : PR 20110101
Title: Prostate cancer cell lines under hypoxia exhibit greater stem-like properties.
Journal: PloS one 20110101
Title: Biological activities and medicinal properties of Cajanus cajan (L) Millsp.
Journal: Journal of advanced pharmaceutical technology & research 20110101
Title: Effects of newcastle disease virus strains AF2240 and V4-UPM on cytolysis and apoptosis of leukemia cell lines.
Journal: International journal of molecular sciences 20110101
Title: Bioactive constituents and medicinal importance of genus Alnus.
Journal: Pharmacognosy reviews 20110101
Title: The prospective role of plant products in radiotherapy of cancer: a current overview.
Journal: Frontiers in pharmacology 20110101
Title: Triterpenoids from Schleichera oleosa of Darjeeling Foothills and Their Antimicrobial Activity.
Journal: Indian journal of pharmaceutical sciences 20110101
Title: Triterpenoid contents and anti-inflammatory properties of the methanol extracts of ligustrum species leaves.
Journal: Molecules (Basel, Switzerland) 20101223
Title: Betulinic acid inhibits high glucose-induced vascular smooth muscle cells proliferation and migration.
Journal: Journal of cellular biochemistry 20101215
Title: Redefining the TGR5 triterpenoid binding pocket at the C-3 position.
Journal: ChemMedChem 20101203
Title: Immunomodulatory effects of betulinic acid from the bark of white birch on mice.
Journal: Journal of veterinary science 20101201
Title: Antiurolithiatic and antioxidant activity of Mimusops elengi on ethylene glycol-induced urolithiasis in rats.
Journal: Indian journal of pharmacology 20101201
Title: Zfra is a small wizard in the mitochondrial apoptosis.
Journal: Aging 20101201
Title: Extended longevity of Drosophila melanogaster by water and ethanol extracts of Stachys lavandulifolia.
Journal: Pharmaceutical biology 20101101
Title: Inhibition of insulin and T3-induced fatty acid synthase by hexanoate.
Journal: Lipids 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: [Influence of betulinic acid on proliferation, migration, cell cycle and apoptosis of pancreatic cancer cells].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
Title: [Advances in the study of structural modifications and biological activities of betulinic acids].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101101
Title: 3β-Acet-oxy-lup-20(29)-en-28-yl 1H-1,2,4-tri-azole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20101101
Title: Synthesis, cytotoxicity and liposome preparation of 28-acetylenic betulin derivatives.
Journal: Bioorganic & medicinal chemistry 20101015
Title: New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern).
Journal: Fitoterapia 20101001
Title: Antimicrobial and antioxidant effects of phenolic constituents from Klainedoxa gabonensis.
Journal: Pharmaceutical biology 20101001
Title: Antiinflammatory properties of Morus nigra leaves.
Journal: Phytotherapy research : PTR 20101001
Title: Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Journal: Toxins 20101001
Title: Synthesis, proapoptotic screening, and structure-activity relationships of novel aza-lupane triterpenoids.
Journal: Bioorganic & medicinal chemistry letters 20100915
Title: Two new flavones from Tridax procumbens Linn.
Journal: Molecules (Basel, Switzerland) 20100909
Title: Exploring the potential of Nelumbo nucifera rhizome on membrane stabilization, mast cell protection, nitric oxide synthesis, and expression of costimulatory molecules.
Journal: Immunopharmacology and immunotoxicology 20100901
Title: Conjugates of betulin derivatives with AZT as potent anti-HIV agents.
Journal: Bioorganic & medicinal chemistry 20100901
Title: [Betulinic acid ameliorates impairment of endothelium-dependent relaxation induced by oxidative stress in rat aorta].
Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20100901
Title: Betulinic acid isolated from Bacopa monniera (L.) Wettst suppresses lipopolysaccharide stimulated interleukin-6 production through modulation of nuclear factor-kappaB in peripheral blood mononuclear cells.
Journal: International immunopharmacology 20100801
Title: Small structural changes of pentacyclic lupane type triterpenoid derivatives lead to significant differences in their anticancer properties.
Journal: European journal of medicinal chemistry 20100801
Title: Modulation of apoptosis by natural products for cancer therapy.
Journal: Planta medica 20100801
Title: Antitumor effect of betulinic acid on human acute leukemia K562 cells in vitro.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100801
Title: Synthesis and anticancer activity of novel betulinic acid and betulin derivatives.
Journal: Archiv der Pharmazie 20100801
Title: Last stop before exit - hepatitis C assembly and release as antiviral drug targets.
Journal: Viruses 20100801
Title: Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.
Journal: International journal of cancer 20100715
Title: Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells.
Journal: Molecular and cellular biochemistry 20100701
Title: Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors.
Journal: Current diabetes reviews 20100701
Title: A new steroidal glycoside and fatty acid esters from the stem bark of Tectona grandis Linn.
Journal: Natural product research 20100701
Title: Betulin induces mitochondrial cytochrome c release associated apoptosis in human cancer cells.
Journal: Molecular carcinogenesis 20100701
Title: 3β-Hy-droxy-lup-20(29)-en-28-yl 1H-imidazole-1-carboxyl-ate.
Journal: Acta crystallographica. Section E, Structure reports online 20100701
Title: Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma.
Journal: British journal of cancer 20100629
Title: Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.
Journal: Bioorganic & medicinal chemistry 20100615
Title: Betulinic acid stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells: involvement of BMP/Runx2 and beta-catenin signals.
Journal: Journal of agricultural and food chemistry 20100609
Title: Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites.
Journal: DNA repair 20100604
Title: Anti-angiogenic and cytotoxicity studies of some medicinal plants.
Journal: Planta medica 20100601
Title: Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation.
Journal: Pharmacological research 20100601
Title: Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601
Title: Carbamate derivatives of betulinic acid and betulin with selective cytotoxic activity.
Journal: Bioorganic & medicinal chemistry letters 20100601
Title: Acylated manoyl oxide diterpenes of Stemodia trifoliata.
Journal: Magnetic resonance in chemistry : MRC 20100601
Title: Nonsurgical innovations in the treatment of nonmelanoma skin cancer.
Journal: The Journal of clinical and aesthetic dermatology 20100601
Title: [Studies on the chemical constituents of Callicarpa kochiana].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100601
Title: [Studies on the triterpenoids of Vitex trifolia].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100601
Title: Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.
Journal: Journal of natural products 20100528
Title: Anti-leukemic activity of Dillenia indica L. fruit extract and quantification of betulinic acid by HPLC.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100501
Title: Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells.
Journal: Molecular cancer research : MCR 20100501
Title: In vitro anticancer studies of alpha- and beta-D-glucopyranose betulin anomers.
Journal: Chemico-biological interactions 20100429
Title: Anti-AIDS agents 81. Design, synthesis, and structure-activity relationship study of betulinic acid and moronic acid derivatives as potent HIV maturation inhibitors.
Journal: Journal of medicinal chemistry 20100422
Title: Antiprotozoal activity of betulinic acid derivatives.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100401
Title: Minor secondary metabolic products from the stem bark of Plumeria rubra Linn. displaying antimicrobial activities.
Journal: Planta medica 20100401
Title: Synthesis and biological evaluation of antitumor-active gamma-butyrolactone substituted betulin derivatives.
Journal: Bioorganic & medicinal chemistry 20100401
Title: A pentacyclic triterpene from Litchi chinensis.
Journal: Natural product communications 20100401
Title: Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
Journal: Journal of natural products 20100326
Title: Bioactivity-guided isolation of cytotoxic triterpenoids from the trunk of Berberis koreana.
Journal: Bioorganic & medicinal chemistry letters 20100315
Title: Betulinic acid protects against ischemia/reperfusion-induced renal damage and inhibits leukocyte apoptosis.
Journal: Phytotherapy research : PTR 20100301
Title: Anti-HIV-1 and anti-inflammatory lupanes from the leaves, twigs, and resin of Garcinia hanburyi.
Journal: Planta medica 20100301
Title: Betulinic acid, a natural compound with potent anticancer effects.
Journal: Anti-cancer drugs 20100301
Title: Anti-leishmanial activity of betulin derivatives.
Journal: The Journal of antibiotics 20100301
Title: Betulinic acid a radiosensitizer in head and neck squamous cell carcinoma cell lines.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20100301
Title: Antiproliferative effect of extracts from Aristolochia baetica and Origanum compactum on human breast cancer cell line MCF-7.
Journal: Pharmaceutical biology 20100301
Title: Antiproliferative cardenolides from Pentopetia androsaemifolia Decne. from the Madagascar rain forest.
Journal: Indian journal of experimental biology 20100301
Title: Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives.
Journal: Bioorganic & medicinal chemistry 20100215
Title: Effects of triterpene derivatives from Maytenus rigida on VEGF-induced Kaposi's sarcoma cell proliferation.
Journal: Chemico-biological interactions 20100212
Title: Augmentation of expression of immunocytes' functions by seed extract of Ziziphus mauritiana (Lamk.).
Journal: Journal of ethnopharmacology 20100203
Title: Synthesis and biological evaluation of antitumour-active betulin derivatives.
Journal: Bioorganic & medicinal chemistry 20100201
Title: Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
Journal: Journal of medicinal chemistry 20100114
Title: Synthesis of a molecularly imprinted polymer for the solid-phase extraction of betulin and betulinic acid from plane bark.
Journal: Phytochemical analysis : PCA 20100101
Title: Protective role of betulinic acid on TNF-alpha-induced cell adhesion molecules in vascular endothelial cells.
Journal: Biochemical and biophysical research communications 20100101
Title: Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells.
Journal: Acta pharmacologica Sinica 20100101
Title: Molecular interaction studies of trimethoxy flavone with human serum albumin.
Journal: PloS one 20100101
Title: Indigenous use and bio-efficacy of medicinal plants in the Rasuwa District, Central Nepal.
Journal: Journal of ethnobiology and ethnomedicine 20100101
Title: Effects of hydroxy pentacyclic triterpene acids from Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea pigs.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV- 1 maturation inhibitor bevirimat.
Journal: Retrovirology 20100101
Title: Anticancer activity of 3-O-acylated betulinic acid derivatives obtained by enzymatic synthesis.
Journal: Bioscience, biotechnology, and biochemistry 20100101
Title: Possible fungistatic implications of betulin presence in betulaceae plants and their hymenochaetaceae parasitic fungi.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101
Title: Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.
Journal: The American journal of Chinese medicine 20100101
Title: NF-kappaB activation enhances cell death by antimitotic drugs in human prostate cancer cells.
Journal: Molecular cancer 20100101
Title: Rapid validated HPTLC method for estimation of betulinic acid in Nelumbo nucifera (Nymphaeaceae) rhizome extract.
Journal: Phytochemical analysis : PCA 20100101
Title: Peroxynitrite mediates diabetes-induced endothelial dysfunction: possible role of Rho kinase activation.
Journal: Experimental diabetes research 20100101
Title: Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.
Journal: Parasites & vectors 20100101
Title: Baculovirus display of single chain antibody (scFv) using a novel signal peptide.
Journal: BMC biotechnology 20100101
Title: Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation.
Journal: PloS one 20100101
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
Journal: BMC cancer 20100101
Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.
Journal: Journal of ethnobiology and ethnomedicine 20100101
Title: Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel.
Journal: Journal of inflammation (London, England) 20100101
Title: Triterpenoids from Psidium guajava with Biocidal Activity.
Journal: Indian journal of pharmaceutical sciences 20100101
Title: Bioactivity of Syzygium jambos methanolic extracts: Antibacterial activity and toxicity.
Journal: Pharmacognosy research 20100101
Title: Diuretic and natriuretic activity of two mistletoe species in rats.
Journal: Pharmacognosy research 20100101
Title: Cameroonian medicinal plants: pharmacology and derived natural products.
Journal: Frontiers in pharmacology 20100101
Title: Ethnopharmacology and integrative medicine - Let the history tell the future.
Journal: Journal of Ayurveda and integrative medicine 20100101
Title: Betulinic acid derivatives as human immunodeficiency virus type 2 (HIV-2) inhibitors.
Journal: Journal of medicinal chemistry 20091210
Title: Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy.
Journal: Planta medica 20091201
Title: Bioactive constituents of the stem bark of Beilschmiedia zenkeri.
Journal: Journal of natural products 20091201
Title: Pharmacotherapy of actinic keratosis.
Journal: Expert opinion on pharmacotherapy 20091201
Title: The hunt for natural skin whitening agents.
Journal: International journal of molecular sciences 20091201
Title: Phytotoxic activity of Salvia x jamensis.
Journal: Natural product communications 20091201
Title: Triterpenoids as new promising anticancer drugs.
Journal: Anti-cancer drugs 20091101
Title: Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Journal: Chemical biology & drug design 20091101
Title: Betulin-derived compounds as inhibitors of alphavirus replication.
Journal: Journal of natural products 20091101
Title: A lichen substance as an antiproliferative compound against HL-60 human leukemia cells: 16-O-acetyl-leucotylic acid isolated from Myelochroa aurulenta.
Journal: Bioscience, biotechnology, and biochemistry 20091101
Title: Anticancer agents derived from natural products.
Journal: Mini reviews in medicinal chemistry 20091101
Title: [Studies on the chemical constituents from the seed of Forsythia suspense].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101
Title: Betulinic acid, a natural pentacyclic triterpenoid, prevents abdominal fat accumulation in mice fed a high-fat diet.
Journal: Journal of agricultural and food chemistry 20091014
Title: Palbinone and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant human HepG2 Cells.
Journal: Bioorganic & medicinal chemistry letters 20091001
Title: Betulinic acid treatment promotes apoptosis in hepatoblastoma cells.
Journal: International journal of oncology 20091001
Title: [Effect of betulinic acid on inducing apoptosis of human multiple myeloma cell line RPMI-8226].
Journal: Zhongguo shi yan xue ye xue za zhi 20091001
Title: Recent developments in anti-inflammatory natural products.
Journal: Medicinal research reviews 20090901
Title: Phytochemical and antifungal studies on Terminalia mollis and Terminalia brachystemma.
Journal: Fitoterapia 20090901
Title: Mitochondrial membrane potential disruption pattern in human sperm.
Journal: Human reproduction (Oxford, England) 20090901
Title: Targeting mitochondrial apoptosis by betulinic acid in human cancers.
Journal: Drug discovery today 20090901
Title: Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity.
Journal: Bioorganic & medicinal chemistry 20090901
Title: Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.
Journal: Journal of natural products 20090901
Title: Study on determination of pentacyclic triterpenoids in Chaenomeles by HPLC-ELSD.
Journal: Journal of chromatographic science 20090901
Title: Antifungal activity of Eugenia umbelliflora against dermatophytes.
Journal: Natural product communications 20090901
Title: [Chemical constituents from fruits of Ailanthus altissima].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901
Title: [Studies on the chemical constituents of Coleus forskohlii].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090901
Title: Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo.
Journal: International journal of cancer 20090815
Title: Esters of betulin and betulinic acid with amino acids have improved water solubility and are selectively cytotoxic toward cancer cells.
Journal: Bioorganic & medicinal chemistry letters 20090815
Title: Antimicrobial activity of the crude extract, fractions and compounds from stem bark of Ficus ovata (Moraceae).
Journal: Journal of ethnopharmacology 20090730
Title: High-performance liquid chromatography--two wavelength detection of triterpenoid acids from the fruits of Ziziphus jujuba containing various cultivars in different regions and classification using chemometric analysis.
Journal: Journal of pharmaceutical and biomedical analysis 20090712
Title: Antimalarial activity of betulinic acid and derivatives in vitro against Plasmodium falciparum and in vivo in P. berghei-infected mice.
Journal: Parasitology research 20090701
Title: Cancer preventive agents 9. Betulinic acid derivatives as potent cancer chemopreventive agents.
Journal: Bioorganic & medicinal chemistry letters 20090701
Title: Phytochemical analyses and gastroprotective effects of Eugenia umbelliflora (Myrtaceae) on experimental gastric ulcers.
Journal: Natural product communications 20090701
Title: A new lipid and other constituents from the rhizomes of Nelumbo nucifera.
Journal: Journal of Asian natural products research 20090701
Title: Triterpenoids from the roots of Pterospermum heterophyllum Hance.
Journal: Journal of Asian natural products research 20090701
Title: Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
Journal: Molecules (Basel, Switzerland) 20090604
Title: Bioactive triterpenoids from Callistemon lanceolatus.
Journal: Archives of pharmacal research 20090601
Title: Curtisia dentata (Cornaceae) leaf extracts and isolated compounds inhibit motility of parasitic and free-living nematodes.
Journal: The Onderstepoort journal of veterinary research 20090601
Title: 2'-Methyl-pyrazolo[4',3':16,17]androst-5-en-3β-ol.
Journal: Acta crystallographica. Section E, Structure reports online 20090601
Title: Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.
Journal: Journal of medicinal chemistry 20090528
Title: Characterization of NVX-207, a novel betulinic acid-derived anti-cancer compound.
Journal: European journal of clinical investigation 20090501
Title: Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression.
Journal: The FEBS journal 20090501
Title: Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines.
Journal: Molecules (Basel, Switzerland) 20090424
Title: Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products.
Journal: Bioorganic & medicinal chemistry letters 20090415
Title: Synthesis and cytotoxicity of 2-cyano-28-hydroxy-lup-1-en-3-ones.
Journal: Bioorganic & medicinal chemistry letters 20090415
Title: Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins.
Journal: Bioorganic & medicinal chemistry 20090301
Title: Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis.
Journal: International immunopharmacology 20090201
Title: Acasiane A and B and farnesirane A and B, diterpene derivatives from the roots of Acacia farnesiana.
Journal: Planta medica 20090201
Title: Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion.
Journal: Apoptosis : an international journal on programmed cell death 20090201
Title: Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae).
Journal: Inflammopharmacology 20090201
Title: Peltophorum africanum, a traditional South African medicinal plant, contains an anti HIV-1 constituent, betulinic acid.
Journal: The Tohoku journal of experimental medicine 20090201
Title: Identification and isolation of pharmacologically active triterpenes in Betuale cortex, Betula pendula Roth., Betulaceae.
Journal: Bosnian journal of basic medical sciences 20090201
Title: Antioxidative action of methanolic extract and buthanolic fraction of Vochysia tucanorum Mart. in the gastroprotection.
Journal: Journal of ethnopharmacology 20090130
Title: Enhancing the divergent activities of betulinic acid via neoglycosylation.
Journal: Organic letters 20090115
Title: Betulinic acid binding to human serum albumin: a study of protein conformation and binding affinity.
Journal: Journal of photochemistry and photobiology. B, Biology 20090109
Title: Isolation of betulinic acid, its methyl ester and guaiane sesquiterpenoids with protein tyrosine phosphatase 1B inhibitory activity from the roots of Saussurea lappa C.B.Clarke.
Journal: Molecules (Basel, Switzerland) 20090108
Title: Uapaca genus (Euphorbiaceae), a good source of betulinic acid.
Journal: Fitoterapia 20090101
Title: Analysis of pentacyclic triterpenes by LC-MS. A comparative study between APCI and APPI.
Journal: Journal of mass spectrometry : JMS 20090101
Title: Betulinic acid: a natural product with anticancer activity.
Journal: Molecular nutrition & food research 20090101
Title: Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins.
Journal: Journal of natural products 20090101
Title: Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
Journal: Journal of translational medicine 20090101
Title: Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.
Journal: PloS one 20090101
Title: [Drug discovery based on classic natural products].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090101
Title: Betulin is a potent anti-tumor agent that is enhanced by cholesterol.
Journal: PloS one 20090101
Title: Mechanism of betulinic acid inhibition of collagen biosynthesis in human endometrial adenocarcinoma cells.
Journal: Neoplasma 20090101
Title: Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Antimalarial compounds from the stem bark of Vismia laurentii.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101
Title: Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation.
Journal: PloS one 20090101
Title: Chemical composition of the stem bark and leaves of Ficus pandurata Hance.
Journal: Natural product research 20090101
Title: Prevention of atherosclerosis by interference with the vascular nitric oxide system.
Journal: Current pharmaceutical design 20090101
Title: Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera.
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20090101
Title: Betulinic acid does not modulate the activity of P-gp/ABCB1 or MRP1/ABCC1 in a non-tumoral renal cell line: Possible utility in multidrug resistance cancer chemotherapy.
Journal: Molecular medicine reports 20090101
Title: Betulinic acid exhibits stronger cytotoxic activity on the normal melanocyte NHEM-neo cell line than on drug-resistant and drug-sensitive MeWo melanoma cell lines.
Journal: Molecular medicine reports 20090101
Title: Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection.
Journal: Journal of pharmaceutical and biomedical analysis 20081215
Title: Triterpene based compounds with potent anti-maturation activity against HIV-1.
Journal: Bioorganic & medicinal chemistry letters 20081215
Title: Enhanced analysis of triterpenes, flavonoids and phenolic compounds in Prunella vulgaris L. by capillary zone electrophoresis with the addition of running buffer modifiers.
Journal: Journal of chromatography. A 20081212
Title: Betulinic acid suppresses constitutive and TNFalpha-induced NF-kappaB activation and induces apoptosis in human prostate carcinoma PC-3 cells.
Journal: Molecular carcinogenesis 20081201
Title: Effect of hydrogen peroxide on secretory response, calcium mobilisation and caspase-3 activity in the isolated rat parotid gland.
Journal: Molecular and cellular biochemistry 20081201
Title: Effects of betulinic acid on proliferation and apoptosis in Jurkat cells and its in vitro mechanism.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20081201
Title: Screening of Chinese medicinal plants for inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
Journal: Journal of ethnopharmacology 20081120
Title: Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
Journal: Journal of ethnopharmacology 20081120
Title: Two novel triterpenoids with antiproliferative and apoptotic activities in human leukemia cells isolated from the resin of Garcinia hanburyi.
Journal: Planta medica 20081101
Title: Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana.
Journal: Bioorganic & medicinal chemistry 20081101
Title: Study of antimalarial activity of chemical constituents from Diospyros quaesita.
Journal: Chemistry & biodiversity 20081101
Title: Determination of betulinic acid from Orthosiphon stamineus leaf extract in rat plasma.
Journal: Die Pharmazie 20081101
Title: Betulin binds to gamma-aminobutyric acid receptors and exerts anticonvulsant action in mice.
Journal: Pharmacology, biochemistry, and behavior 20081001
Title: Phytochemical composition and in vitro pharmacological activity of two rose hip (Rosa canina L.) preparations.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20081001
Title: Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.
Journal: Journal of natural products 20081001
Title: Four pentacyclic triterpenoids with antifungal and antibacterial activity from Curtisia dentata (Burm.f) C.A. Sm. leaves.
Journal: Journal of ethnopharmacology 20080926
Title: Efficient access to 2-isobetulinic acid, 2-isooleanolic acid, and 2-isoursolic acid.
Journal: The Journal of organic chemistry 20080919
Title: Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivatives.
Journal: Bioorganic & medicinal chemistry letters 20080915
Title: Conventional and dense gas techniques for the production of liposomes: a review.
Journal: AAPS PharmSciTech 20080901
Title: Cancer is a preventable disease that requires major lifestyle changes.
Journal: Pharmaceutical research 20080901
Title: Comparison with various parts of Broussonetia papyrifera as to the antinociceptive and anti-inflammatory activities in rodents.
Journal: Bioscience, biotechnology, and biochemistry 20080901
Title: Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds.
Journal: Indian journal of experimental biology 20080901
Title: Lupane-type triterpenoids from Microtropis fokienensis and Perrottetia arisanensis and the apoptotic effect of 28-hydroxy-3-oxo-lup-20(29)-en-30-al.
Journal: Journal of natural products 20080801
Title: [Studies on chemical constituents from stem barks of Fraxinus paxiana].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801
Title: [Studies on chemical constituents from roots of Pterospermum heterophyllum].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080801
Title: [Effect of betulinic acid on proliferation and apoptosis in Jurkat cells and its mechanism].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080801
Title: In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
Journal: British journal of cancer 20080722
Title: Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.
Journal: Cellular signalling 20080701
Title: Nitric oxide induces caspase activity in boar spermatozoa.
Journal: Theriogenology 20080701
Title: Antibacterial activity of labdane diterpenoids from Stemodia foliosa.
Journal: Journal of natural products 20080701
Title: [Chemical constituents from herb of Gueldenstaedtia stenophylla].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080701
Title: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
Journal: Journal of medicinal chemistry 20080626
Title: A new source of whitening agent from a Thai Mulberry plant and its betulinic acid quantitation.
Journal: Natural product research 20080615
Title: Fas receptor is not present on ejaculated human sperm.
Journal: Human reproduction (Oxford, England) 20080601
Title: Investigation of Indian diospyros species for antiplasmodial properties.
Journal: Evidence-based complementary and alternative medicine : eCAM 20080601
Title: Betulinic Acid for cancer treatment and prevention.
Journal: International journal of molecular sciences 20080601
Title: Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.
Journal: Carbohydrate research 20080505
Title: alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.
Journal: Journal of natural products 20080501
Title: A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta.
Journal: Archives of pharmacal research 20080501
Title: Inhibitors of DNA polymerase beta: activity and mechanism.
Journal: Bioorganic & medicinal chemistry 20080415
Title: [RP-HPLC determination of betulinic acid in Callicarpa macrophylla].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401
Title: Chemical constituents of radix Ranunculus ternati.
Journal: Natural product research 20080215
Title: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.
Journal: Investigational new drugs 20080201
Title: Antimycobacterial activity of cinnamate-based esters of the triterpenes betulinic, oleanolic and ursolic acids.
Journal: Chemical & pharmaceutical bulletin 20080201
Title: Anti-plasmodial and cholinesterase inhibiting activities of some constituents of Psorospermum glaberrimum.
Journal: Chemical & pharmaceutical bulletin 20080201
Title: [Study on triterpenes from of Ligularia xanthotricha].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201
Title: Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.
Journal: Antimicrobial agents and chemotherapy 20080101
Title: Isolation of cytotoxic metabolites from targeted peruvian amazonian medicinal plants.
Journal: Journal of natural products 20080101
Title: Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells.
Journal: Breast cancer research : BCR 20080101
Title: Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity.
Journal: AIDS research and therapy 20080101
Title: PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.
Journal: PPAR research 20080101
Title: HA14-1 is able to reconstitute the impaired mitochondrial pathway of apoptosis in renal cell carcinoma cell lines.
Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology 20080101
Title: The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain.
Journal: Virology journal 20080101
Title: Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species-mediated apoptotic topoisomerase I-DNA cleavable complex formation in prostate cancer cells but does not affect the process of cell death.
Journal: Cancer research 20071215
Title: Antielastase and free radical scavenging activities of compounds from the stems of Cornus kousa.
Journal: Phytotherapy research : PTR 20071201
Title: Anti-AIDS agents 73: structure-activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives.
Journal: Bioorganic & medicinal chemistry letters 20071201
Title: Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum.
Journal: Phytotherapy research : PTR 20071101
Title: 2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells.
Journal: Carcinogenesis 20071101
Title: Cimicifuga foetida extract inhibits proliferation of hepatocellular cells via induction of cell cycle arrest and apoptosis.
Journal: Journal of ethnopharmacology 20071101
Title: Activation and inhibition of the proteasome by betulinic acid and its derivatives.
Journal: FEBS letters 20071016
Title: Antimicrobial activity of the methanolic extract, fractions and compounds from the stem bark of Irvingia gabonensis (Ixonanthaceae).
Journal: Journal of ethnopharmacology 20071008
Title: Effect of betulinic acid on anticancer drug-resistant colon cancer cells.
Journal: Basic & clinical pharmacology & toxicology 20071001
Title: [Chemical constituents in the root of Cynanchum auriculatum].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001
Title: Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3beta-O-monodesmosidic saponins starting from betulin.
Journal: Bioorganic & medicinal chemistry 20070915
Title: Inhibition of Escherichia coli heat-labile enterotoxin-induced diarrhea by Chaenomeles speciosa.
Journal: Journal of ethnopharmacology 20070905
Title: Goniothalamus species: a source of drugs for the treatment of cancers and bacterial infections?
Journal: Evidence-based complementary and alternative medicine : eCAM 20070901
Title: In vitro anti-Candida Activity of Zataria multiflora Boiss.
Journal: Evidence-based complementary and alternative medicine : eCAM 20070901
Title: Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus.
Journal: Journal of medicinal chemistry 20070823
Title: Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
Journal: Journal of natural products 20070801
Title: High-performance thin-layer chromatographic method for quantitative determination of 4alpha-methyl-24beta-ethyl-5alpha-cholesta-14,25-dien-3beta-ol, 24beta-ethylcholesta-5,9(11),22E-trien-3beta-ol, and betulinic acid in Clerodendrum inerme.
Journal: Journal of separation science 20070801
Title: Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.
Journal: Molecular cancer therapeutics 20070701
Title: The constituents from the stems of Garcinia cowa Roxb. and their cytotoxic activities.
Journal: Die Pharmazie 20070701
Title: Broad in vitro efficacy of plant-derived betulinic acid against cell lines derived from the most prevalent human cancer types.
Journal: Cancer letters 20070618
Title: Antimicrobial activity of oleanolic acid from Salvia officinalis and related compounds on vancomycin-resistant enterococci (VRE).
Journal: Biological & pharmaceutical bulletin 20070601
Title: Antiviral triterpenoids from the medicinal plant Schefflera heptaphylla.
Journal: Phytotherapy research : PTR 20070501
Title: In vitro evaluation of the cytotoxic and trypanocidal activities of Ampelozizyphus amazonicus (Rhamnaceae).
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070501
Title: Triterpenoid pyrazines and benzopyrazines with cytotoxic activity.
Journal: Journal of natural products 20070401
Title: Two new triterpenoids and a steroidal glycoside from the aerial parts of Ocimum basilicum.
Journal: Chemical & pharmaceutical bulletin 20070401
Title: Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors.
Journal: Cancer research 20070315
Title: Triterpenoids from Eugenia grandis: structure elucidation by NMR spectroscopy.
Journal: Magnetic resonance in chemistry : MRC 20070301
Title: Biotransformation of betulinic and betulonic acids by fungi.
Journal: Phytochemistry 20070301
Title: alpha-Glucosidase inhibitory pentacyclic triterpenes from the stem bark of Fagara tessmannii (Rutaceae).
Journal: Phytochemistry 20070301
Title: Synthesis and cytotoxic activity of 17-carboxylic acid modified 23-hydroxy betulinic acid ester derivatives.
Journal: Bioorganic & medicinal chemistry letters 20070301
Title: Anti-plasmodial activity of some constituents of the root bark of Harungana madagascariensis LAM. (Hypericaceae).
Journal: Chemical & pharmaceutical bulletin 20070301
Title: Two new flavanone glycosides of Jasminum lanceolarium and their anti-oxidant activities.
Journal: Chemical & pharmaceutical bulletin 20070301
Title: [Studies on chemical constituents in fruits of Eucalyptus globulus].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070301
Title: Simultaneous determination of betulin and betulinic acid in white birch bark using RP-HPLC.
Journal: Journal of pharmaceutical and biomedical analysis 20070219
Title: A new multiparameter flow cytometric method for human semen analysis.
Journal: Human reproduction (Oxford, England) 20070201
Title: Antidermatophytic triterpenoids from Syzygium jambos (L.) Alston (Myrtaceae).
Journal: Phytotherapy research : PTR 20070201
Title: [Biological activity tests of chemical constituents from two Brazilian Labiatae plants].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070201
Title: Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L.
Journal: Planta medica 20070201
Title: New developments in natural products-based anti-AIDS research.
Journal: Medicinal research reviews 20070101
Title: Comparison of plants used for skin and stomach problems in Trinidad and Tobago with Asian ethnomedicine.
Journal: Journal of ethnobiology and ethnomedicine 20070101
Title: Phytochemical investigation of Perovskia abrotanoides.
Journal: Planta medica 20070101
Title: Betulin binds to melanocortin receptors and antagonizes alpha-melanocyte stimulating hormone induced cAMP generation in mouse melanoma cells.
Journal: Cell biochemistry and function 20070101
Title: New flavonoids and other constituents from Lespedeza cuneata.
Journal: Journal of Asian natural products research 20070101
Title: Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice.
Journal: PloS one 20070101
Title: The oncoprotein H-RasV12 increases mitochondrial metabolism.
Journal: Molecular cancer 20070101
Title: [Effect of nitrogen-containing derivatives of the plant triterpenes betulin and glycyrrhetic acid on the growth of MT-4, MOLT-4, CEM, and Hep G2 tumor cells].
Journal: Bioorganicheskaia khimiia 20070101
Title: The 3-O-(3',3'-dimethylsuccinyl) derivative of betulinic acid (DSB) inhibits the assembly of virus-like particles in HIV-1 Gag precursor-expressing cells.
Journal: Antiviral therapy 20070101
Title: Targeting human immunodeficiency virus type 1 assembly, maturation and budding.
Journal: Drug target insights 20070101
Title: Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A.
Journal: Bioorganic & medicinal chemistry letters 20061215
Title: Determinants of activity of the HIV-1 maturation inhibitor PA-457.
Journal: Virology 20061201
Title: Physical, chemical and pharmacological characterization of a new oleogel-forming triterpene extract from the outer bark of birch (betulae cortex).
Journal: Planta medica 20061201
Title: Anti-HIV-1 constituents from leaves and twigs of Cratoxylum arborescens.
Journal: Planta medica 20061201
Title: Antihyperglycemic activity and chemical constituents of Eysenhardtia platycarpa.
Journal: Journal of natural products 20061201
Title: Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.
Journal: Bioorganic & medicinal chemistry 20061001
Title: Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061001
Title: Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents.
Journal: Journal of medicinal chemistry 20060907
Title: Triterpenic and other lipophilic components from industrial cork byproducts.
Journal: Journal of agricultural and food chemistry 20060906
Title: Pharmacological properties of the ubiquitous natural product betulin.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060901
Title: [Studies on triterpenoids from Potentilla chinensis].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060901
Title: Topical anti-inflammatory activity of 2alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.
Journal: Bioorganic & medicinal chemistry 20060815
Title: A new assault on HIV.
Journal: Scientific American 20060601
Title: 3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of the human immunodeficiency virus type 1 Gag precursor assembled in vitro.
Journal: Journal of virology 20060601
Title: Loading of erythrocyte membrane with pentacyclic triterpenes inhibits Plasmodium falciparum invasion.
Journal: Planta medica 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Betulinic acid derivatives as anticancer agents: structure activity relationship.
Journal: Anti-cancer agents in medicinal chemistry 20060501
Title: Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives.
Journal: Bioorganic & medicinal chemistry 20060401
Title: Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodiana.
Journal: Chemical & pharmaceutical bulletin 20060401
Title: Two new 18-en-oleane derivatives from marine mangrove plant, Barringtonia racemosa.
Journal: Die Pharmazie 20060401
Title: Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.
Journal: International journal of cancer 20060301
Title: Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines.
Journal: Journal of natural products 20060301
Title: Cytotoxic terpenes and lignans from the roots of Ainsliaea acerifolia.
Journal: Archives of pharmacal research 20060301
Title: Antiproliferative terpenoids from almond hulls (Prunus dulcis): identification and structure-activity relationships.
Journal: Journal of agricultural and food chemistry 20060208
Title: Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ.
Journal: Biological & pharmaceutical bulletin 20060201
Title: [Treatment of actinic keratoses with birch bark extract: a pilot study].
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20060201
Title: Inhibition of diacylglycerol acyltransferase by betulinic acid from Alnus hirsuta.
Journal: Planta medica 20060201
Title: [Studies on chemical constituents of hairy root of Cassia obtusifolia].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201
Title: Betulinic acid, a natural cytotoxic agent, fails to trigger apoptosis in human Burkitt's lymphoma-derived B-cell lines.
Journal: International journal of cancer 20060101
Title: Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.
Journal: Medicinal research reviews 20060101
Title: [Antimitochondrial agents: a new class of anticancer agents].
Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20060101
Title: Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine.
Journal: BMC cell biology 20060101
Title: [Biological activity and pharmacological prospects of lupane terpenoids: I. Natural lupane derivatives].
Journal: Bioorganicheskaia khimiia 20060101
Title: Dereplication of pentacyclic triterpenoids in plants by GC-EI/MS.
Journal: Phytochemical analysis : PCA 20060101
Title: Chemical study of triterpenoid resinous materials in archaeological findings by means of direct exposure electron ionisation mass spectrometry and gas chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: Is translational research compatible with preclinical publication strategies?
Journal: Radiation oncology (London, England) 20060101
Title: Activation of apoptosis by derivatives of betulinic acid in human tumor cells in vitro.
Journal: Doklady. Biochemistry and biophysics 20060101
Title: A disease epidemic on Zizyphus mucronata in the Kruger National Park caused by Coniodictyum chevalieri.
Journal: Studies in mycology 20060101
Title: Inhibition of HIV-1 maturation via drug association with the viral Gag protein in immature HIV-1 particles.
Journal: The Journal of biological chemistry 20051223
Title: A new bisabolane sesquiterpenoid from Euphorbia chrysocoma.
Journal: Journal of Asian natural products research 20051201
Title: Lupane-triterpenes from Bupleurum flavum.
Journal: Natural product research 20051201
Title: [Studies on the chemical constituents in root of Coleus forskohlii].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051101
Title: Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy.
Journal: Oncogene 20051020
Title: Antibacterial triterpenes from Syzygium guineense (Myrtaceae).
Journal: Journal of ethnopharmacology 20051003
Title: Betulinic acid induces apoptosis in skin cancer cells and differentiation in normal human keratinocytes.
Journal: Experimental dermatology 20051001
Title: Phospholipid nanosomes.
Journal: Current drug delivery 20051001
Title: [Chemical constituents from the mangrove plant Ceriops tagal].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051001
Title: Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats.
Journal: Journal of ethnopharmacology 20050914
Title: Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide.
Journal: The Biochemical journal 20050901
Title: Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid.
Journal: International journal of oncology 20050901
Title: Combination of betulinic acid with cisplatin--different cytotoxic effects in two head and neck cancer cell lines.
Journal: Oncology reports 20050901
Title: [Mitochondrial damage in human sperm caused by the antineoplastic agent betulinic acid].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050801
Title: Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: possible implications for anticancer therapy.
Journal: The Journal of pharmacology and experimental therapeutics 20050801
Title: Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
Journal: Journal of natural products 20050801
Title: Antibacterial constituents from fruit bodies of ascomyce Bulgaria inquinans.
Journal: Archives of pharmacal research 20050801
Title: [Chemical investingation of Chinese mangrove Sonneratia apetala II].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801
Title: Lupane triterpenoids from Maytenus species.
Journal: Journal of natural products 20050701
Title: The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.
Journal: Expert opinion on investigational drugs 20050601
Title: Chemical constituents and antioxidant activity of Mallotus roxburghianus leaves.
Journal: Chemistry & biodiversity 20050601
Title: Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity.
Journal: Bioorganic & medicinal chemistry 20050516
Title: Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis.
Journal: Phytochemistry 20050501
Title: Betulinic acid and its derivatives, potent DNA topoisomerase II inhibitors, from the bark of Bischofia javanica.
Journal: Chemistry & biodiversity 20050501
Title: Caspase activation in human spermatozoa in response to physiological and pathological stimuli.
Journal: Fertility and sterility 20050401
Title: Betulinic acid induces apoptosis in human chronic myelogenous leukemia (CML) cell line K-562 without altering the levels of Bcr-Abl.
Journal: Toxicology letters 20050315
Title: Effect of water and temperature stress on the content of active constituents of Hypericum brasiliense Choisy.
Journal: Plant physiology and biochemistry : PPB 20050301
Title: Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.
Journal: Journal of natural products 20050201
Title: Sensitization for anticancer drug-induced apoptosis by betulinic Acid.
Journal: Neoplasia (New York, N.Y.) 20050201
Title: The chemical constituents of Rhododendron ovatum Planch.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050201
Title: Four new prenylated isoflavonoids in Tadehagi triquetrum.
Journal: Journal of agricultural and food chemistry 20050126
Title: Apoptosis inducing activity of viscin, a lipophilic extract from Viscum album L.
Journal: The Journal of pharmacy and pharmacology 20050101
Title: Betulinic acid derivatives as HIV-1 antivirals.
Journal: Trends in molecular medicine 20050101
Title: Betulinic acid and its derivatives: a review on their biological properties.
Journal: Current medicinal chemistry 20050101
Title: Bioactive triterpenoids from Vochysia pacifica interact with cyclic nucleotide phosphodiesterase isozyme PDE4.
Journal: Phytotherapy research : PTR 20050101
Title: Quantitative analysis of 23-hydroxybetulinic acid in mouse plasma using electrospray liquid chromatography/mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: [Synthesis and antitumor activity of cyclopropane derivatives of betulinic and betulonic acids].
Journal: Bioorganicheskaia khimiia 20050101
Title: Protective effects of betulin and betulinic acid against ethanol-induced cytotoxicity in HepG2 cells.
Journal: Pharmacological reports : PR 20050101
Title: Quantitative structure-cytotoxicity relationship analysis of betulinic acid and its derivatives by semi-empirical molecular-orbital method.
Journal: Anticancer research 20050101
Title: Purification of betulinic acid from Eugenia florida (Myrtaceae) by high-speed counter-current chromatography.
Journal: Phytochemical analysis : PCA 20050101
Title: Chemosensitization and radiosensitization of tumors by plant polyphenols.
Journal: Antioxidants & redox signaling 20050101
Title: 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents.
Journal: Bioorganic & medicinal chemistry letters 20041206
Title: A new flavone from Hypericum wightianum.
Journal: Journal of Asian natural products research 20041201
Title: Protection of Ewing's sarcoma family tumor (ESFT) cell line SK-N-MC from betulinic acid induced apoptosis by alpha-DL-tocopherol.
Journal: Toxicology letters 20041102
Title: Anti-complementary activity of triterpenoides from fruits of Zizyphus jujuba.
Journal: Biological & pharmaceutical bulletin 20041101
Title: Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents.
Journal: Cancer research 20041015
Title: Cooperation of betulinic acid and TRAIL to induce apoptosis in tumor cells.
Journal: Oncogene 20041007
Title: From chemoprevention to chemotherapy: common targets and common goals.
Journal: Expert opinion on investigational drugs 20041001
Title: Cytotoxic saponins from Schefflera rotundifolia.
Journal: Planta medica 20041001
Title: Immobilized betulinic acid column and its interactions with phospholipase A2 and snake venom proteins.
Journal: Journal of separation science 20041001
Title: Apoptotic activity of betulinic acid derivatives on murine melanoma B16 cell line.
Journal: European journal of pharmacology 20040913
Title: Constituents of Senecio chionophilus with potential antitubercular activity.
Journal: Journal of natural products 20040901
Title: Evaluation of bioactive saponins and triterpenoidal aglycons for their binding properties on human endothelin ETA and angiotensin AT1 receptors.
Journal: Phytotherapy research : PTR 20040901
Title: Synthesis and cytotoxic activity of 3-O-acyl/3-hydrazine /2-bromo/20,29-dibromo betulinic acid derivatives.
Journal: Bioorganic & medicinal chemistry letters 20040802
Title: Betulinic acid-induced apoptosis in leukemia cells.
Journal: Leukemia 20040801
Title: [Inhibitory effects of some traditional medicines on proliferation of HIV-1 and its protease].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040801
Title: Rapid analysis of triterpenic acids by liquid chromatography using porous graphitic carbon and evaporative light scattering detection.
Journal: Journal of separation science 20040801
Title: Cell death induction by betulinic acid, ceramide and TRAIL in primary glioblastoma multiforme cells.
Journal: Acta neurochirurgica 20040701
Title: Betulinic acid enhances 1alpha,25-dihydroxyvitamin D3-induced differentiation in human HL-60 promyelocytic leukemia cells.
Journal: Anti-cancer drugs 20040701
Title: Differential expression of three oxidosqualene cyclase mRNAs in Glycyrrhiza glabra.
Journal: Biological & pharmaceutical bulletin 20040701
Title: Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity.
Journal: Journal of natural products 20040701
Title: Synthesis of 3-O-acyl/3-benzylidene/3-hydrazone/3-hydrazine/17-carboxyacryloyl ester derivatives of betulinic acid as anti-angiogenic agents.
Journal: Bioorganic & medicinal chemistry letters 20040621
Title: Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil.
Journal: Journal of agricultural and food chemistry 20040602
Title: Isolation and structure of gustastatin from the Brazilian nut tree Gustavia hexapetala.
Journal: Journal of natural products 20040601
Title: New 3-O-acyl betulinic acids from Strychnos vanprukii Craib.
Journal: Journal of natural products 20040601
Title: Antitubercular constituents of Valeriana laxiflora.
Journal: Planta medica 20040601
Title: Betulinic acid and its derivatives as anti-angiogenic agents.
Journal: Bioorganic & medicinal chemistry letters 20040503
Title: Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.
Journal: British journal of cancer 20040419
Title: Marmenol: a 7-geranyloxycoumarin from the leaves of Aegle marmelos Corr.
Journal: Natural product research 20040401
Title: Betulinic acid: a promising anticancer candidate.
Journal: IDrugs : the investigational drugs journal 20040401
Title: Cytotoxic lupane-type triterpenoids from Acacia mellifera.
Journal: Phytochemistry 20040401
Title: Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina.
Journal: Planta medica 20040301
Title: Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.
Journal: Antimicrobial agents and chemotherapy 20040201
Title: Apoptosis-modulating agents in combination with radiotherapy-current status and outlook.
Journal: International journal of radiation oncology, biology, physics 20040201
Title: Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea.
Journal: Phytotherapy research : PTR 20040201
Title: Antiplasmodial constituents of Cajanus cajan.
Journal: Phytotherapy research : PTR 20040201
Title: Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase.
Journal: Archives of pharmacal research 20040201
Title: Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.
Journal: Bioorganic & medicinal chemistry 20040102
Title: Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection.
Journal: Medicinal research reviews 20040101
Title: New prenylated isoflavanones and other constituents of Lespedeza bicolor.
Journal: Fitoterapia 20040101
Title: Role of the ectodomain of the gp41 transmembrane envelope protein of human immunodeficiency virus type 1 in late steps of the membrane fusion process.
Journal: Journal of virology 20040101
Title: Steroids and triterpenes from Eleocharis acutangula and E. sellowiana (Cyperaceae).
Journal: Phytochemical analysis : PCA 20040101
Title: The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid.
Journal: Retrovirology 20040101
Title: Apoptosis of human carcinoma cells in the presence of potential anti-cancer drugs: III. Treatment of Colo-205 and SKBR3 cells with: cis -platin, Tamoxifen, Melphalan, Betulinic acid, L-PDMP, L-PPMP, and GD3 ganglioside.
Journal: Glycoconjugate journal 20040101
Title: Constituents of Quinchamalium majus with potential antitubercular activity.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Title: New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships.
Journal: Journal of medicinal chemistry 20031204
Title: Immunomodulatory activity of betulinic acid by producing pro-inflammatory cytokines and activation of macrophages.
Journal: Archives of pharmacal research 20031201
Title: News from the bench.
Journal: GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20031201
Title: [Studies on the constituents from the stems of Spatholobus suberectus].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031201
Title: Antitumor-promoting constituents from Chaenomeles sinensis KOEHNE and their activities in JB6 mouse epidermal cells.
Journal: Chemical & pharmaceutical bulletin 20031101
Title: A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta.
Journal: Journal of natural products 20031101
Title: Cytotoxic triterpenoids from the fruits of Zizyphus jujuba.
Journal: Planta medica 20031101
Title: Lupane triterpenes and derivatives with antiviral activity.
Journal: Bioorganic & medicinal chemistry letters 20031020
Title: Synthesis and cytotoxic activity of A-ring modified betulinic acid derivatives.
Journal: Bioorganic & medicinal chemistry letters 20031006
Title: Antiplasmodial triterpenes from twigs of Gardenia saxatilis.
Journal: Journal of ethnopharmacology 20031001
Title: Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030915
Title: A review of natural and modified betulinic, ursolic and echinocystic acid derivatives as potential antitumor and anti-HIV agents.
Journal: Mini reviews in medicinal chemistry 20030901
Title: Betulinic acid: a new cytotoxic compound against malignant head and neck cancer cells.
Journal: Head & neck 20030901
Title: Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase.
Journal: Journal of natural products 20030901
Title: Antiviral activity of betulin, betulinic and betulonic acids against some enveloped and non-enveloped viruses.
Journal: Fitoterapia 20030701
Title: Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701
Title: A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2'-deoxy-adenosine (cladribine) and 2-chloro-adenosine in human astrocytoma cells.
Journal: Molecular pharmacology 20030601
Title: Broncho-vasodilatory activity of fractions and pure constituents isolated from Bacopa monniera.
Journal: Journal of ethnopharmacology 20030501
Title: A new acylglycosyl sterol from Quisqualis Fructus.
Journal: Archives of pharmacal research 20030401
Title: New ursolic and betulinic derivatives as potential cytotoxic agents.
Journal: Journal of enzyme inhibition and medicinal chemistry 20030401
Title: New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata.
Journal: Journal of natural products 20030301
Title: Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L.
Journal: Phytotherapy research : PTR 20030201
Title: Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
Journal: Journal of natural products 20030201
Title: Constituents of antibacterial extract of Caesalpinia paraguariensis Burk.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
Title: [Epimerization of hydroxyl group in the lupan series of triterpenes].
Journal: Bioorganicheskaia khimiia 20030101
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