Home Amines 4740-24-3
4740-24-3,MFCD00002536
Catalog No.:AA003K3X

4740-24-3 | 4-(Butylamino)benzoic acid

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Purity
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250mg
97%
in stock  
$15.00   $11.00
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5g
97%
in stock  
$119.00   $83.00
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25g
97%
in stock  
$440.00   $308.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003K3X
Chemical Name:
4-(Butylamino)benzoic acid
CAS Number:
4740-24-3
Molecular Formula:
C11H15NO2
Molecular Weight:
193.2423
MDL Number:
MFCD00002536
SMILES:
CCCCNc1ccc(cc1)C(=O)O
NSC Number:
44300
Properties
Properties
 
Form:
Solid  
MP:
149-151 °C(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
174  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
3.4  

Upstream Synthesis Route

[1]JournaloftheSocietyofChemicalIndustry,London,1945,vol.64,p.177

[2]Patent:US1889645,1932,,

[3]Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.19,p.1536

[4]BioorganicandMedicinalChemistryLetters,2008,vol.18,#2,p.645-649

[1]Patent:US1889645,1932,,

[2]Patent:US1889645,1932,,

[1]JournalofOrganicChemistry,2007,vol.72,#25,p.9815-9817

[2]JournalofMedicinalChemistry,2011,vol.54,#13,p.4904-4912

[3]Patent:US2014/18422,2014,A1,.Locationinpatent:Paragraph0098

[1]JournalofOrganicChemistry,2007,vol.72,#25,p.9815-9817

[1]BioorganicandMedicinalChemistryLetters,2008,vol.18,#2,p.645-649

Downstream Synthesis Route

[1]JournaloftheSocietyofChemicalIndustry,1945,vol.64,p.177

[2]BioorganicandMedicinalChemistryLetters,2008,vol.18,p.645-649

1004-75-7    5221-17-0    4740-24-3   
10-butyl-pteroicacid 

[1]JournaloftheAmericanChemicalSociety,1948,vol.70,p.1922,1925

14925-39-4    4740-24-3   
1-butyl-6-carboxy-quinolinium;bromide 

[1]Patent:DE825409,1951,    DRP/DRBPOrg.Chem.,

[1]JournalofMolecularStructure,2014,vol.1082,p.23-28

[2]Patent:US1889645,1932,

[1]JournaloftheSocietyofChemicalIndustry,1945,vol.64,p.177

[2]ZeitschriftfurChemie,1980,vol.20,p.259-260

Literature

Title: Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.

Journal: Neuroscience letters 20120111

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells.

Journal: Anesthesia and analgesia 20080601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: A novel in vitro percutaneous penetration model: evaluation of barrier properties with p-aminobenzoic acid and two of its derivatives.

Journal: Pharmaceutical research 20060501

Title: The block of total and N-type calcium conductance in mouse sensory neurons by the local anesthetic n-butyl-p-aminobenzoate.

Journal: Anesthesia and analgesia 20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: A sudden death following tetracaine-induced spinal anesthesia.

Journal: Legal medicine (Tokyo, Japan) 20020301

Title: Distribution of tetracaine and its metabolite in rabbits after high versus normal spinal anesthesia.

Journal: Forensic science international 20011227

Title: Blood concentrations of tetracaine and its metabolite following spinal anesthesia.

Journal: Forensic science international 20010201

Title: Simultaneous determination of mepivacaine, tetracaine, and p-butylaminobenzoic acid by high-performance liquid chromatography.

Journal: Journal of pharmacological and toxicological methods 20010101

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