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4964-14-1,MFCD00872098
Catalog No.:AA01CCLK

4964-14-1 | Arsine oxide, trimethyl-

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25mg
3 weeks  
$456.00   $319.00
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100mg
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$749.00   $524.00
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1g
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$4,676.00   $3,273.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CCLK
Chemical Name:
Arsine oxide, trimethyl-
CAS Number:
4964-14-1
Molecular Formula:
C3H9AsO
Molecular Weight:
136.0246
MDL Number:
MFCD00872098
SMILES:
C[As](=O)(C)C
Properties
Properties
 
Form:
Solid  
MP:
188 - 192°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
53  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
1  

Literature

Title: Modulation of aryl hydrocarbon receptor-regulated enzymes by trimethylarsine oxide in C57BL/6 mice: In vivo and in vitro studies.

Journal: Toxicology letters 20151001

Title: Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20150101

Title: Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

Journal: Free radical biology & medicine 20140201

Title: Detoxification system for inorganic arsenic: transformation of As2O3 into TMAO by vitamin B12 derivatives and conversion of TMAO into arsenobetaine.

Journal: Chemical communications (Cambridge, England) 20081107

Title: Cytotoxicity of combinations of arsenicals on rat urinary bladder urothelial cells in vitro.

Journal: Toxicology 20080710

Title: Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder.

Journal: Toxicology and applied pharmacology 20070615

Title: Chronic exposure to methylated arsenicals stimulates arsenic excretion pathways and induces arsenic tolerance in rat liver cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060501

Title: A comparative study of the sub-chronic toxic effects of three organic arsenical compounds on the urothelium in F344 rats; gender-based differences in response.

Journal: Toxicology and applied pharmacology 20060201

Title: Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.

Journal: Chemical research in toxicology 20041201

Title: Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate.

Journal: Analytical chemistry 20031201

Title: Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats--association with oxidative DNA damage and enhanced cell proliferation.

Journal: Carcinogenesis 20031101

Title: Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism.

Journal: International journal of cancer 20020710

Title: Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.

Journal: Toxicology and applied pharmacology 20011215

Title: Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.

Journal: Chemical research in toxicology 19980401

Title: The reduction of trimethylarsine oxide by Candida humicola.

Journal: Canadian journal of microbiology 19810801

Title: The transformation of arsenicals by Candida humicola.

Journal: Canadian journal of microbiology 19791001

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