Title: Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.
Journal: Oncotarget 20161129
Title: Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
Journal: The Journal of thoracic and cardiovascular surgery 20140101
Title: Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay.
Journal: Antimicrobial agents and chemotherapy 20121201
Title: Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
Journal: Leukemia research 20120601
Title: Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20120401
Title: Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
Journal: PloS one 20120101
Title: Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Journal: International journal of oncology 20111001
Title: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Journal: Cancer research 20110901
Title: The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer.
Journal: Oncotarget 20110801
Title: HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma.
Journal: Oral oncology 20110601
Title: Redundant and differential roles of transcription factors Gli1 and Gli2 in the development of mouse fetal Leydig cells.
Journal: Biology of reproduction 20110501
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Journal: Cancer research 20110201
Title: Modulators of the hedgehog signaling pathway.
Journal: Bioorganic & medicinal chemistry 20100915
Title: Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Journal: Oncogene 20100902
Title: Gli2 expression and human bladder transitional carcinoma cell invasiveness.
Journal: The Journal of urology 20100701
Title: Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.
Journal: Bioorganic & medicinal chemistry 20100701
Title: Mazumdar T, et al. Hedgehog signaling drives cellular survival in human colon carcinoma cells. Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Fu J, et al. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. Cancer Lett. 2013 Mar 1;330(1):22-32.
Title: Wickstrom M, et al. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo. Int J Cancer. 2013 Apr 1;132(7):1516-24.
