+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 50773-41-6
50773-41-6,MFCD09026938
Catalog No.:AA00DA2C

50773-41-6 | Polyphyllin D

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$173.00   $121.00
- +
10mg
≥95%
in stock  
$262.00   $183.00
- +
25mg
97%
in stock  
$550.00   $385.00
- +
50mg
≥95%
in stock  
$1,032.00   $722.00
- +
100mg
97%
in stock  
$1,593.00   $1,115.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DA2C
Chemical Name:
Polyphyllin D
CAS Number:
50773-41-6
Molecular Formula:
C44H70O16
Molecular Weight:
855.0170
MDL Number:
MFCD09026938
SMILES:
OC[C@H]1O[C@@H](O[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3CC[C@]3([C@H]4C[C@H]4[C@@H]3[C@H](C)[C@]3(O4)CC[C@H](CO3)C)C)C2)C)[C@@H]([C@H]([C@@H]1O[C@@H]1O[C@H]([C@@H]([C@H]1O)O)CO)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1570  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
25  
Heavy Atom Count:
60  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
8  
XLogP3:
1.5  

Literature

Title: Polyphyllin I induces cell cycle arrest and apoptosis in human myeloma cells via modulating β-catenin signaling pathway.

Journal: European journal of haematology 20161001

Title: Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft.

Journal: Acta biochimica et biophysica Sinica 20101101

Title: Kong M, et al. Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft. Acta Biochim Biophys Sin (Shanghai). 2010 Nov;42(11):827-33.

Title: Liu J, et al. Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway. Acta Biochim Biophys Sin (Shanghai). 2017 Jun 1;49(6):479-486.

Title: He J, et al. Polyphyllin I induces autophagy and cell cycle arrest via inhibiting PDK1/Akt/mTOR signal and downregulating cyclin B1 in human gastric carcinoma HGC-27 cells. Biomed Pharmacother. 2019 Sep;117:109189.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 50773-41-6
102115-79-7

102115-79-7

 126105-11-1

126105-11-1

 474-58-8

474-58-8

 88901-36-4

88901-36-4

 11021-14-0

11021-14-0

 19716-26-8

19716-26-8
Building Blocks
More >
Tags:50773-41-6 Molecular Formula|50773-41-6 MDL|50773-41-6 SMILES|50773-41-6 Polyphyllin D