Home Deuterated Building Blocks 5144-52-5
5144-52-5,MFCD00014316
Catalog No.:AA00DDZU

5144-52-5 | 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole; nitric acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(HPLC)
in stock  
$24.00   $17.00
- +
5g
98%(HPLC)
in stock  
$34.00   $24.00
- +
25g
95%
in stock  
$70.00   $49.00
- +
100g
95%
in stock  
$195.00   $137.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DDZU
Chemical Name:
2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole; nitric acid
CAS Number:
5144-52-5
Molecular Formula:
C14H15N3O3
Molecular Weight:
273.2872
MDL Number:
MFCD00014316
SMILES:
C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.[N+](=O)(O)[O-]
Properties
Properties
 
Form:
Solid  
MP:
167-170 °C  
Stability:
Hygroscopic  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
297  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Literature

Title: Dilute brimonidine to improve patient comfort and subconjunctival hemorrhage after LASIK.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20130701

Title: Spectroscopic analyses on interaction of Naphazoline hydrochloride with bovine serum albumin.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

Title: α1-adrenergic drugs exhibit affinity to a thapsigargin-sensitive binding site and interfere with the intracellular Ca2+ homeostasis in human erythroleukemia cells.

Journal: Experimental cell research 20111210

Title: α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanism.

Journal: Experimental cell research 20111001

Title: Topical naphazoline in the treatment of myasthenic blepharoptosis.

Journal: Muscle & nerve 20110701

Title: Construction and performance characterization of screen printed and carbon paste ion selective electrodes for potentiometric determination of naphazoline hydrochloride in pharmaceutical preparations.

Journal: The Analyst 20110121

Title: Online naphazoline quality control by micellar-enhanced spectrofluorimetry.

Journal: Luminescence : the journal of biological and chemical luminescence 20110101

Title: Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).

Journal: Molecular vision 20110101

Title: Pulmonary edema and prolonged awakening after nasal naphazoline application in a transspenoidal hypophysectomy patient.

Journal: Journal of neurosurgical anesthesiology 20100701

Title: Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives.

Journal: Bioorganic & medicinal chemistry 20100415

Title: Pharmacological characterization of a Bombyx mori alpha-adrenergic-like octopamine receptor stably expressed in a mammalian cell line.

Journal: Archives of insect biochemistry and physiology 20100201

Title: A comparative kinetic and mechanistic study between tetrahydrozoline and naphazoline toward photogenerated reactive oxygen species.

Journal: Photochemistry and photobiology 20100101

Title: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.

Journal: European journal of ophthalmology 20100101

Title: Simultaneous determination of antazoline and naphazoline by the net analyte signal standard addition method and spectrophotometric technique.

Journal: Journal of AOAC International 20100101

Title: Allergic contact dermatitis from dibucaine hydrochloride, chlorpheniramine maleate, and naphazoline hydrochloride in an over-the-counter topical antiseptic.

Journal: Contact dermatitis 20090701

Title: Influence of the ageing phenomenon on the low-frequency electrical impedance behavior of naphazoline hydrochloride solutions and paracetamol syrup.

Journal: Journal of pharmaceutical sciences 20090501

Title: Intranasal lidocaine plus naphazoline nitrate improves surgical conditions and perioperative analgesia in septorhinoplasty surgery.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20090201

Title: [Peritopic anesthesia in cataract surgery].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20090201

Title: A presentation of longstanding toxoplasmosis chorioretinitis.

Journal: Optometry (St. Louis, Mo.) 20090101

Title: Flow-injection chemiluminescence method for the determination of naphazoline hydrochloride and oxymetazoline hydrochloride.

Journal: Luminescence : the journal of biological and chemical luminescence 20090101

Title: Nasal irrigation with lavonase as ancillary treatment of acute rhinosinusitis: a pilot study.

Journal: Journal of biological regulators and homeostatic agents 20090101

Title: [Microhemocirculation and its correction in duodenal ulcer during period of rehabilitation].

Journal: Likars'ka sprava 20090101

Title: Simultaneous determination of dibucaine and naphazoline in human serum by monolithic silica spin column extraction and liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080901

Title: Relationship between rhinitis duration and response to nasal decongestion test.

Journal: The Laryngoscope 20080701

Title: Acute pulmonary edema associated with naphazoline ingestion.

Journal: Clinical toxicology (Philadelphia, Pa.) 20080301

Title: [The influence of different alpha-sympathomimetic drugs and benzalkoniumchlorid on the ciliary beat frequency of in vitro cultured human nasal mucosa cells].

Journal: Laryngo- rhino- otologie 20080101

Title: Ischemic stroke in a man with naphazoline abuse history.

Journal: The American journal of emergency medicine 20071001

Title: Eyelid ptosis from sympathetic nerve dysfunction mistaken as myopathy: a simple test to identify this condition.

Journal: Journal of neurology, neurosurgery, and psychiatry 20070601

Title: Theoretical assessment of naphazoline redoxchemistry and photochemistry.

Journal: The journal of physical chemistry. B 20070419

Title: Nasal eosinophils and reversibility to the decongestion test in patients with perennial allergic rhinitis.

Journal: Allergy and asthma proceedings 20070101

Title: Ebastine improves nasal symptoms and airflow and affects response to decongestion test in patients with persistent allergic rhinitis: a pilot study.

Journal: Allergy and asthma proceedings 20070101

Title: Naphazoline intoxication in children.

Journal: European journal of pediatrics 20061101

Title: Different mechanisms between thromboxane A2- and leukotriene D4-induced nasal blockage in guinea pigs.

Journal: Prostaglandins & other lipid mediators 20060901

Title: Effect of cold BSS vs naphazoline 0.025% on ocular surface temperature.

Journal: Eye (London, England) 20060801

Title: Evaluation, in vitro, of the radioprotection of DNA from gamma-rays by naphazoline.

Journal: Comptes rendus biologies 20060301

Title: Association between response to decongestion testing and sensitizations and allergic inflammation.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301

Title: Do topical nasal decongestants affect polyps?

Journal: Acta oto-laryngologica 20060301

Title: A rapid derivative spectrophotometric method for simultaneous determination of naphazoline and antazoline in eye drops.

Journal: Chemical & pharmaceutical bulletin 20060101

Title: Early bronchial airflow impairment in patients with persistent allergic rhinitis and bronchial hyperreactivity.

Journal: Respiratory medicine 20051201

Title: [Efficacy of Derinox assessed with one PNIF (Peak Nasal Inspiratory Flow) in patients suffering from common cold].

Journal: Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris 20051101

Title: A fluorescence optosensor for analyzing naphazoline in pharmaceutical preparations. Comparison with other sensors.

Journal: Journal of pharmaceutical and biomedical analysis 20050715

Title: A comparison of the clinical efficacy of pheniramine maleate/naphazoline hydrochloride ophthalmic solution and olopatadine hydrochloride ophthalmic solution in the conjunctival allergen challenge model.

Journal: Clinical therapeutics 20050501

Title: Levocetirizine improves nasal symptoms and airflow in patients with persistent allergic rhinitis: a pilot study.

Journal: European annals of allergy and clinical immunology 20050101

Title: [The application of naphcon eye drops during Lasik surgery].

Journal: Yan ke xue bao = Eye science 20041201

Title: Hemorrhagic stroke after naphazoline exposition: case report.

Journal: Arquivos de neuro-psiquiatria 20040901

Title: Course and therapy of intoxication with imidazoline derivate naphazoline.

Journal: International journal of pediatric otorhinolaryngology 20040701

Title: Comparison of three different phosphorescent methodologies in solution for the analysis of naphazoline in pharmaceutical preparations.

Journal: Analytical and bioanalytical chemistry 20040501

Title: [Pharmacological correction of cochleovestibular impairments].

Journal: Vestnik otorinolaringologii 20040101

Title: [The tolerability of nasal drugs with special regard to preservatives and physico-chemical parameters].

Journal: Laryngo- rhino- otologie 20031101

Title: Octopaminergic modulation of synaptic transmission between an identified sensory afferent and flight motoneuron in the locust.

Journal: The Journal of comparative neurology 20030714

Title: Naphazoline intoxication in a child-a clinical and forensic toxicological case.

Journal: Forensic science international 20030708

Title: [Adult cases of naphazoline-containing antiseptic first aid liquid poisoning].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20030701

Title: [Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult].

Journal: Annales francaises d'anesthesie et de reanimation 20030501

Title: Simultaneous determination of naphazoline, diphenhydramine and phenylephrine in nasal solutions by capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20030205

Title: [Naphazoline intoxication: course and therapy].

Journal: Laryngo- rhino- otologie 20030201

Title: [Acute exposure to imidazoline derivatives in children].

Journal: Jornal de pediatria 20030101

Title: Complementary use of partial least-squares and artificial neural networks for the non-linear spectrophotometric analysis of pharmaceutical samples.

Journal: Analytical and bioanalytical chemistry 20021001

Title: Bilateral acute angle-closure glaucoma after use of Fenox nasal drops.

Journal: Eye (London, England) 20020901

Title: Naphazoline-induced neuroendocrine changes: increases in ANP and cGMP levels, but suppression of NE, 3H-NE, and cAMP levels in rabbit eyes.

Journal: Pharmacology 20020701

Title: [She really loves Mickey...].

Journal: La Revue de medecine interne 20020601

Title: [Applications of phosphorimetry in pharmaceutical analysis].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20020601

Title: Prolonged awakening and pulmonary edema after general anesthesia and naphazoline application in an infant.

Journal: Anesthesia and analgesia 20011101

Title: Treatment of ulcerative endobronchial tuberculosis and bronchial stenosis with aerosolized streptomycin and steroids.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20010801

Title: [Electron microscopic studies of the rabbit nasal mucosa after short-term application of naphzoline nitrate].

Journal: Laryngo- rhino- otologie 20010701

Title: Involvement of nitric oxide in pollen-induced biphasic nasal blockage in sensitised guinea pigs.

Journal: European journal of pharmacology 20010629

Title: Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities.

Journal: European journal of medicinal chemistry 20010501

Title: Naphazoline-induced suppression of aqueous humor pressure and flow: involvement of central and peripheral alpha(2)/I(1) receptors.

Journal: Experimental eye research 20010301

Title: Treatment of rhinitis medicamentosa with fluticasone propionate--an experimental study.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20010301

Title: [Comparative study of the radiation-protective effectiveness of low doses of cysteamine, heparin, and naphtizine in experiments on mice].

Journal: Radiatsionnaia biologiia, radioecologiia 20010101

Title: Expression of multiple alpha1-adrenoceptors on vascular smooth muscle: correlation with the regulation of contraction.

Journal: The Journal of pharmacology and experimental therapeutics 19990701

Title: Central action of narcotic analgesics. Part IV. Noradrenergic influences on the activity of analgesics in rats.

Journal: Polish journal of pharmacology and pharmacy 19780101

Title: The influence of alpha-adrenergic drugs on catalepsy induced by haloperidol or fluphenazine in rats.

Journal: Polish journal of pharmacology and pharmacy 19780101

Title: Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.

Journal: The Journal of pharmacology and experimental therapeutics 19680301

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 5144-52-5
Tags:5144-52-5 Molecular Formula|5144-52-5 MDL|5144-52-5 SMILES|5144-52-5 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole; nitric acid