Home Other Heterocycles 51656-90-7
51656-90-7,MFCD07779440
Catalog No.:AA00DE2C

51656-90-7 | 8-Methylidene-1,4-dioxaspiro[4.5]decane

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500mg
95%
in stock  
$66.00   $47.00
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1g
95%
in stock  
$111.00   $78.00
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5g
95%
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$426.00   $298.00
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10g
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$721.00   $505.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DE2C
Chemical Name:
8-Methylidene-1,4-dioxaspiro[4.5]decane
CAS Number:
51656-90-7
Molecular Formula:
C9H14O2
Molecular Weight:
154.2063
MDL Number:
MFCD07779440
SMILES:
C=C1CCC2(CC1)OCCO2
Properties
Computed Properties
 
Complexity:
156  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
1.2  

Downstream Synthesis Route

[1]Nicolaou;Magolda;Claremon[JournaloftheAmericanChemicalSociety,1980,vol.102,#4,p.1404-1409]

[2]Gurjar,MukundK.;Joshi,RameshA.;Chaudhuri,SiddharthaR.;Joshi,ShreerangV.;Barde,AnupR.;Gediya,LaljiK.;Ranade,PrasadV.;Kadam,SureshM.;Naik,SanjayJ.[TetrahedronLetters,2003,vol.44,#26,p.4853-4855]

[3]Inoue,Hirohumi;Murata,Shizuaki;Suzuki,Toshiyasu[LiebigsAnnalenderChemie,1994,#9,p.901-910]

51656-90-7   
(1,4-dioxaspiro4.5dec-8-yl)methanol 

[1]CurrentPatentAssignee:CENTRENATIONALDELARECHERCHESCIENTIFIQUE;Galderma(in:EQTPartners);EqtPartnersAB-US2007/167519,2007,A1Locationinpatent:Page/Pagecolumn7;sheet2

[2]Gurjar,MukundK.;Joshi,RameshA.;Chaudhuri,SiddharthaR.;Joshi,ShreerangV.;Barde,AnupR.;Gediya,LaljiK.;Ranade,PrasadV.;Kadam,SureshM.;Naik,SanjayJ.[TetrahedronLetters,2003,vol.44,#26,p.4853-4855]

[3]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED;4SCAG-WO2008/20045,2008,A1Locationinpatent:Page/Pagecolumn186

[4]Nicolaou;Magolda;Claremon[JournaloftheAmericanChemicalSociety,1980,vol.102,#4,p.1404-1409]

[5]Inoue,Hirohumi;Murata,Shizuaki;Suzuki,Toshiyasu[LiebigsAnnalenderChemie,1994,#9,p.901-910]

[6]CurrentPatentAssignee:CHISSOCORPORATION-US2009/278088,2009,A1

[7]CurrentPatentAssignee:CHISSOCORPORATION-EP2272837,2011,A1Locationinpatent:Page/Pagecolumn33

[1]Rosowsky,Andre;Forsch,RonaldA.;Moran,RichardG.[JournalofMedicinalChemistry,1989,vol.32,#3,p.709-715]

[1]Frontier,AlisonJ.;Danishefsky,SamuelJ.;Koppel,GaryA.;Meng,Dongfang[Tetrahedron,1998,vol.54,#42,p.12721-12736]

[2]CurrentPatentAssignee:EqtPartnersAB;Galderma(in:EQTPartners);CENTRENATIONALDELARECHERCHESCIENTIFIQUE-US2007/167519,2007,A1Locationinpatent:Page/Pagecolumn7;sheet2

[3]Mihovilovic;Chen;Wang;Kyte;Rochon;Kayser;Stewart[JournalofOrganicChemistry,2001,vol.66,#3,p.733-738]

[4]Panchaud,Philippe;Ollivier,Cyril;Renaud,Philippe;Zigmantas,Sarunas[JournalofOrganicChemistry,2004,vol.69,#8,p.2755-2759]

[5]CurrentPatentAssignee:CHINESEACADEMYOFSCIENCES-EP3753926,2020,A1Locationinpatent:Paragraph0228;0229

[6]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2005/87215,2005,A1Locationinpatent:Page/Pagecolumn367-368

[7]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2005/87752,2005,A2Locationinpatent:Page/Pagecolumn138

[8]Kapat,Ajoy;Nyfeler,Erich;Giuffredi,GuyT.;Renaud,Philippe[JournaloftheAmericanChemicalSociety,2009,vol.131,#49,p.17746-17747]

[9]Nóvoa,Luis;Trulli,Laura;Parra,Alejandro;Tortosa,Mariola[AngewandteChemie-InternationalEdition,2021,vol.60,#21,p.11763-11768][Angew.Chem.,2021,vol.133,#21,p.11869-11874,6]

[10]CurrentPatentAssignee:ASSEMBLYBIOSCIENCES,INC.-WO2021/216661,2021,A1Locationinpatent:Page/Pagecolumn58-59

[11]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-WO2019/87028,2019,A1Locationinpatent:Page/Pagecolumn26

[12]DolbierJr.,WilliamR.;Palmer,KeithW.;Tian,Feng;Fiedorow,Piotr;Zaganiaczyk,Andrzej;Koroniak,Henryk[CollectionofCzechoslovakChemicalCommunications,2002,vol.67,#10,p.1517-1532]

[13]CurrentPatentAssignee:HANSOHPHARMACEUTICALGROUPCOLTD-WO2018/130174,2018,A1Locationinpatent:Page/Pagecolumn73-74

[14]Watson,DavidW.;Gill,Matthew;Kemmitt,Paul;Lamont,ScottG.;Popescu,MihaiV.;Simpson,Iain[TetrahedronLetters,2018,vol.59,#51,p.4479-4482]

[15]CurrentPatentAssignee:CHISSOCORPORATION-US2009/278088,2009,A1

[16]CurrentPatentAssignee:CHISSOCORPORATION-EP2272837,2011,A1Locationinpatent:Page/Pagecolumn33

[17]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG;IRMLLC-WO2011/29915,2011,A1Locationinpatent:Page/Pagecolumn60-61

[18]CurrentPatentAssignee:IRMLLC;NOVARTISAG;Novartis(w/oSandoz)-WO2012/120469,2012,A1Locationinpatent:Page/Pagecolumn50

[19]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2012/175520,2012,A1Locationinpatent:Page/Pagecolumn159

[20]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-US2013/289058,2013,A1Locationinpatent:Paragraph0402;0403

[21]CurrentPatentAssignee:PHARMARONINC-WO2014/146490,2014,A1Locationinpatent:Page/Pagecolumn117

[22]CurrentPatentAssignee:PHARMARONINC-WO2014/146246,2014,A1Locationinpatent:Page/Pagecolumn96;97

[23]CurrentPatentAssignee:ABBVIEINC-WO2019/35927,2019,A1Locationinpatent:Paragraph00727

[24]CurrentPatentAssignee:ABBVIEINC-WO2019/35911,2019,A1Locationinpatent:Paragraph00408

[25]Jeyaseelan,Rubaishan;Lautens,Mark;Ross,RachelJ.[OrganicLetters,2020]

[26]CurrentPatentAssignee:SumitomoPharma(in:SumitomoChemical);SumitomoChemical(w/oDongwooFine-Chem);SUMITOMOCHEMICALCOMPANYLIMITED-EP3828174,2021,A1Locationinpatent:Paragraph0174

[27]CurrentPatentAssignee:GOSSAMERBIOINC-WO2021/207549,2021,A1Locationinpatent:Page/Pagecolumn119;120

[1]Frontier,AlisonJ.;Danishefsky,SamuelJ.;Koppel,GaryA.;Meng,Dongfang[Tetrahedron,1998,vol.54,#42,p.12721-12736]

[2]DolbierJr.,WilliamR.;Palmer,KeithW.;Tian,Feng;Fiedorow,Piotr;Zaganiaczyk,Andrzej;Koroniak,Henryk[CollectionofCzechoslovakChemicalCommunications,2002,vol.67,#10,p.1517-1532]

[3]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2005/87751,2005,A2Locationinpatent:Page/Pagecolumn283-284

[4]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2006/10095,2006,A2Locationinpatent:Page/Pagecolumn100

[5]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2005/87215,2005,A1Locationinpatent:Page/Pagecolumn368

[6]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2005/87752,2005,A2Locationinpatent:Page/Pagecolumn138-139

[7]CurrentPatentAssignee:PERRIGOCOMPANYPUBLICLIMITEDCOMPANY-WO2006/10094,2006,A1Locationinpatent:Page/Pagecolumn105

[8]Locationinpatent:schemeortableSealy,JenniferM.;Truong,AnhP.;Tso,Luke;Probst,GaryD.;Aquino,Jose;Hom,RoyK.;Jagodzinska,BarbaraM.;Dressen,Darren;Wone,DavidW.G.;Brogley,Louis;John,Varghese;Tung,JayS.;Pleiss,MichaelA.;Tucker,JohnA.;Konradi,AndreiW.;Dappen,MichaelS.;Toth,Gergely;Pan,Hu;Ruslim,Lany;Miller,Jim;Bova,MichaelP.;Sinha,Sukanto;Quinn,KevinP.;Sauer,John-Michael[BioorganicandMedicinalChemistryLetters,2009,vol.19,#22,p.6386-6391]

[9]CurrentPatentAssignee:IRMLLC;NOVARTISAG;Novartis(w/oSandoz)-WO2011/29915,2011,A1Locationinpatent:Page/Pagecolumn60

[10]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz);IRMLLC-WO2012/120469,2012,A1Locationinpatent:Page/Pagecolumn50

[11]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-WO2012/175520,2012,A1Locationinpatent:Page/Pagecolumn158-159

[12]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-US2013/289058,2013,A1Locationinpatent:Paragraph0402;0403;0404

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Tags:51656-90-7 Molecular Formula|51656-90-7 MDL|51656-90-7 SMILES|51656-90-7 8-Methylidene-1,4-dioxaspiro[4.5]decane