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519-37-9,MFCD00055055
Catalog No.:AA003N9C

519-37-9 | Etofylline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$6.00   $4.00
- +
1g
95%
in stock  
$29.00   $20.00
- +
5g
95%
in stock  
$54.00   $38.00
- +
10g
≥98%
in stock  
$63.00   $44.00
- +
25g
>98.0%(HPLC)(N)
in stock  
$101.00   $71.00
- +
100g
95%
in stock  
$344.00   $241.00
- +
500g
>98.0%(HPLC)(N)
in stock  
$746.00   $522.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003N9C
Chemical Name:
Etofylline
CAS Number:
519-37-9
Molecular Formula:
C9H12N4O3
Molecular Weight:
224.2166
MDL Number:
MFCD00055055
SMILES:
OCCn1cnc2c1c(=O)n(C)c(=O)n2C
NSC Number:
113373
Properties
Properties
 
BP:
495.5°C at 760 mmHg  
Form:
Solid  
MP:
163 °C  
Refractive Index:
1.6300 (estimate)  
Solubility:
H2O: Solutions may be stored for several days at 4°C.soluble  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
322  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
-1.2  

Literature

Title: Prodrugs of theophylline incorporating ethyleneoxy groups in the promoiety: synthesis, characterization, and transdermal delivery.

Journal: AAPS PharmSciTech 20120901

Title: Preclinical evaluation of the antineoplastic efficacy of 7-(2-hydroxyethyl)theophylline on melanoma cancer cells.

Journal: Melanoma research 20120401

Title: On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library. 3. Focus on ion trap and upfront CID.

Journal: Journal of mass spectrometry : JMS 20120201

Title: Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods.

Journal: European journal of medicinal chemistry 20100801

Title: A liquid chromatography method for quantifying caffeine dissolution from pharmaceutical formulations into colloidal, fat-rich media.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100701

Title: Surface-imprinted nanostructured layer-by-layer film for molecular recognition of theophylline derivatives.

Journal: Langmuir : the ACS journal of surfaces and colloids 20081021

Title: Simultaneous determination of multi drug components Theophylline, Etofylline, Guaiphenesine and Ambroxol Hydrochloride by validated RP-HPLC method in liquid dosage form.

Journal: Pakistan journal of pharmaceutical sciences 20080401

Title: Simultaneous determination of salbutamol sulphate, bromhexine hydrochloride and etofylline in pharmaceutical formulations with the use of four rapid derivative spectrophotometric methods.

Journal: Analytica chimica acta 20070730

Title: A simple and rapid HPLC/UV method for the simultaneous quantification of theophylline and etofylline in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Investigation of the aqueous dissolution of semicrystalline poly(ethylene oxide) using infrared chemical imaging: the effects of molecular weight and crystallinity.

Journal: Applied spectroscopy 20050801

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: The effects of intravenously administered methylxanthines on the proportion of goblet cells containing fucosylated glycoconjugates in rabbit tracheal epithelium.

Journal: Acta histochemica 20040201

Title: Method development for determining the antibacterial linezolid in human serum by micellar electrokinetic capillary chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

Journal: Journal of medicinal chemistry 20020523

Title: The effects of intravenously administered methylxanthine preparations on the glycoconjugate composition of goblet cells in rabbit tracheal epithelium.

Journal: Acta histochemica 20020101

Title: Determination of theophylline by HPLC and GC-IDMS, the effect of chemically similar xanthine derivatives on the specificity of the method and the possibility of paracetamol as interfering substance.

Journal: Clinical laboratory 20020101

Title: Siemon G, et, al. [The effect of fominoben and oxyethyltheophylline in combination on pulmonary function and pulmonary hemodynamics in chronic-obstructive diseases of the airways (author's transl) Arzneimittelforschung. 1978;28(4):698-700.

Title: Ufkes JG, et, al. Efficacy of theophylline and its N-7-substituted derivatives in experimentally induced bronchial asthma in the guinea-pig. Arch Int Pharmacodyn Ther. 1981 Oct;253(2):301-14.

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