Home Carboxes 531-81-7
531-81-7,MFCD00006852
Catalog No.:AA003OZY

531-81-7 | Coumarin-3-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$6.00   $4.00
- +
5g
98%
in stock  
$7.00   $5.00
- +
10g
98%
in stock  
$11.00   $8.00
- +
25g
98%
in stock  
$23.00   $16.00
- +
100g
98%
in stock  
$73.00   $51.00
- +
500g
98%
in stock  
$325.00   $227.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003OZY
Chemical Name:
Coumarin-3-carboxylic acid
CAS Number:
531-81-7
Molecular Formula:
C10H6O4
Molecular Weight:
190.1522
MDL Number:
MFCD00006852
SMILES:
OC(=O)c1cc2ccccc2oc1=O
Properties
Properties
 
BP:
388.6°C at 760 mmHg  
Form:
Solid  
MP:
189-192°C(lit.);  
Refractive Index:
1.5380 (estimate)  
Solubility:
13g/l  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
305  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.2  

Literature

Title: Improving the antidepressant action and the bioavailability of sertraline by co-crystallization with coumarin 3-carboxylate. Structural determination.

Journal: Chemico-biological interactions 20160405

Title: Synthesis and biological evaluation of coumarin derivatives as inhibitors of Mycobacterium bovis (BCG).

Journal: Chemical biology & drug design 20121201

Title: A novel luminescent terbium-3-carboxycoumarin probe for time-resolved fluorescence sensing of pesticides methomyl, aldicarb and prometryne.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Synthesis and antibacterial activities of novel 4-hydroxy-7-hydroxy- and 3-carboxycoumarin derivatives.

Journal: Molecules (Basel, Switzerland) 20120910

Title: Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors.

Journal: Neurochemistry international 20120901

Title: Vanadium bromoperoxidase-coupled fluorescent assay for flow cytometry sorting of glucose oxidase gene libraries in double emulsions.

Journal: Analytical and bioanalytical chemistry 20120901

Title: Mechanism of radiation-induced reactions in aqueous solution of coumarin-3-carboxylic acid: effects of concentration, gas and additive on fluorescent product yield.

Journal: Free radical research 20120701

Title: Fluorescence and electrochemical sensing of pesticides methomyl, aldicarb and prometryne by the luminescent europium-3-carboxycoumarin probe.

Journal: Journal of fluorescence 20120301

Title: Chemical enhancement by nanomaterials under X-ray irradiation.

Journal: Journal of the American Chemical Society 20120201

Title: TiO2 nanoparticles are phototoxic to marine phytoplankton.

Journal: PloS one 20120101

Title: Molecular structure and spectroscopic studies on novel complexes of coumarin-3-carboxylic acid with Ni(II), Co(II), Zn(II) and Mn(II) ions based on density functional theory.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111215

Title: Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato-κO,O)manganese(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110601

Title: Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato)copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110601

Title: Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato-κO,O)cadmium.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Diaqua-bis-(2-oxo-2H-chromene-3-carboxyl-ato)zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Hydroxyl radical and its scavengers in health and disease.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Structural and functional characterization of a promiscuous feruloyl esterase (Est1E) from the rumen bacterium Butyrivibrio proteoclasticus.

Journal: Proteins 20100501

Title: Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.

Journal: Journal of medicinal chemistry 20100114

Title: Cinnamyl 2-oxo-2H-chromene-3-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Menthyl 2-oxo-2H-chromene-3-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo.

Journal: Free radical biology & medicine 20090915

Title: Trans-cinnamic acid and coumarin-3-carboxylic acid: experimental charge-density studies to shed light on [2 + 2] cycloaddition reactions.

Journal: Acta crystallographica. Section B, Structural science 20090401

Title: Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer.

Journal: Journal of hematopathology 20090301

Title: Synergistic effects of metal ion and the pre-senile cataract-causing G98R alphaA-crystallin: self-aggregation propensities and chaperone activity.

Journal: Molecular vision 20090101

Title: 6-Substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives in a new approach of the treatment of cancer cell invasion and metastasis.

Journal: European journal of medicinal chemistry 20081201

Title: Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution.

Journal: International journal of radiation biology 20081201

Title: Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA.

Journal: Biochemistry. Biokhimiia 20080401

Title: Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese Ancistrocladus species related to Ancistrocladus congolensis.

Journal: Phytochemistry 20080201

Title: [Formation of hydrogen peroxide and hydroxyl radicals in aqueous solutions of L-amino acids by the action of X-rays and heat].

Journal: Biofizika 20080101

Title: Anticancer Activity of Ag(I) N-Heterocyclic Carbene Complexes Derived from 4,5-Dichloro-1H-Imidazole.

Journal: Metal-based drugs 20080101

Title: Theoretical study of metal-ligand interaction in Sm(III), Eu(III), and Tb(III) complexes of coumarin-3-carboxylic acid in the gas phase and solution.

Journal: Inorganic chemistry 20071210

Title: Near infrared multiphoton-induced generation and detection of hydroxyl radicals in a biochemical system.

Journal: Archives of biochemistry and biophysics 20070815

Title: Asymmetric total synthesis of (-)-Linderol A.

Journal: The Journal of organic chemistry 20070720

Title: A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells.

Journal: Cancer letters 20070518

Title: In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines.

Journal: Cancer letters 20070418

Title: Biological activity of 3-formylchromones and related compounds.

Journal: In vivo (Athens, Greece) 20070101

Title: New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents.

Journal: Metal-based drugs 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Guanosine and inosine display antioxidant activity, protect DNA in vitro from oxidative damage induced by reactive oxygen species, and serve as radioprotectors in mice.

Journal: Radiation research 20060501

Title: Diels-Alder reactions of 3-substituted coumarins in water and under high-pressure condition. An uncatalyzed route to tetrahydro-6H-benzo[c]chromen-6-ones.

Journal: The Journal of organic chemistry 20060106

Title: (Sub)-picosecond spectral evolution of fluorescence in photoactive proteins studied with a synchroscan streak camera system.

Journal: Photochemistry and photobiology 20060101

Title: Guanosine and inosine as natural antioxidants and radioprotectors for mice exposed to lethal doses of gamma-radiation.

Journal: Doklady. Biochemistry and biophysics 20060101

Title: [Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays].

Journal: Radiatsionnaia biologiia, radioecologiia 20060101

Title: Effects of iron on Vitamin C/copper-induced hydroxyl radical generation in bicarbonate-rich water.

Journal: Free radical research 20050501

Title: Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study.

Journal: Bioorganic & medicinal chemistry letters 20040716

Title: Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms.

Journal: Archives of biochemistry and biophysics 20040415

Title: Fungal modification of the hydroxyl radical detector coumarin-3-carboxylic acid.

Journal: FEMS microbiology ecology 20031101

Title: 2-Amino-1,3-benzothiazole-ethyl coumarin-3-carboxylate (1/1).

Journal: Acta crystallographica. Section C, Crystal structure communications 20031001

Title: Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20030804

Title: Superoxide dismutase: the balance between prevention and induction of oxidative damage.

Journal: Chemico-biological interactions 20030306

Title: [Heat-induced activation of reducing properties of of sea water].

Journal: Biofizika 20030101

Title: Measurement of ascorbic acid (vitamin C) induced hydroxyl radical generation in household drinking water.

Journal: Free radical research 20021201

Title: Detection of hydroxyl radicals produced by wood-decomposing fungi.

Journal: FEMS microbiology ecology 20020401

Title: [Generation of hydroxyl radicals and other redox active compounds in the sea water exposed to heat].

Journal: Biofizika 20020101

Title: Generation of hydroxyl radicals by the antiviral compound phosphonoformic acid (foscarnet).

Journal: Pharmacology & toxicology 20010701

Title: Synthesis and characterization of a binuclear coumarin-3-carboxylate copper(II) complex.

Journal: Journal of inorganic biochemistry 20010301

Title: Aimin Song, et al. A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes or ketones. Tetrahedron Letters. 2003 Feb;44(9): 1755-1758.

Title: Kostova I, et al. New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents. Met Based Drugs. 2007;2007:15925.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:531-81-7 Molecular Formula|531-81-7 MDL|531-81-7 SMILES|531-81-7 Coumarin-3-carboxylic acid