Home Other Heterocycles 532-24-1
532-24-1,MFCD00005549
Catalog No.:AA0035PG

532-24-1 | (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-one

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5g
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$6.00   $4.00
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10g
95%
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$7.00   $5.00
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25g
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0035PG
Chemical Name:
(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-one
CAS Number:
532-24-1
Molecular Formula:
C8H13NO
Molecular Weight:
139.1949
MDL Number:
MFCD00005549
SMILES:
CN1C2CCC1CC(=O)C2
NSC Number:
118012
Properties
Properties
 
BP:
217.1°C at 760 mmHg  
Form:
Solid  
MP:
40-44 °C(lit.)  
Refractive Index:
1.4598 (estimate)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
151  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Undefined Atom Stereocenter Count:
2  
XLogP3:
0.3  

Literature

Title: Total synthesis of (±)-parvineostemonine.

Journal: Chemistry, an Asian journal 20121001

Title: Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.

Journal: Organic & biomolecular chemistry 20120714

Title: Synthesis, characterization, and reaction of a ketone-derived 1,4-dienolate compound.

Journal: The Journal of organic chemistry 20110107

Title: N-Methyl stereochemistry in tropinone: the conformational flexibility of the tropane motif.

Journal: Physical chemistry chemical physics : PCCP 20100621

Title: Asymmetric synthesis of substituted tropinones using the intramolecular mannich cyclization reaction and acyclic N-sulfinyl beta-amino ketone ketals.

Journal: Organic letters 20090402

Title: The functional divergence of short-chain dehydrogenases involved in tropinone reduction.

Journal: The Plant journal : for cell and molecular biology 20080501

Title: An approach for synthesis of tropinone analogue N-substituted with triazine ring.

Journal: Acta poloniae pharmaceutica 20080101

Title: Images in cardiovascular medicine. A rare form of midventricular Tako-Tsubo after emotional stress followed up with magnetic resonance imaging.

Journal: Circulation 20060815

Title: Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.

Journal: Neuroscience letters 20050422

Title: Capturing enzyme structure prior to reaction initiation: tropinone reductase-II-substrate complexes.

Journal: Biochemistry 20030520

Title: Synthesis and muscarinic activities of O-[(benzyl- or benzoyl-pyrazolyl)propynyl]-oximes of N-methylpiperidinone, 3-tropinone, and 3-quinuclidinone.

Journal: Bioorganic & medicinal chemistry 20030515

Title: Biosynthesis of calystegines: 15N NMR and kinetics of formation in root cultures of Calystegia sepium.

Journal: Phytochemistry 20030201

Title: Syntheses and evaluation of pyridazine and pyrimidine containing bioisosteres of (+/-)-pyrido[3.4-b]homotropane and pyrido-[3.4-b]tropane as novel nAChR ligands.

Journal: Bioorganic & medicinal chemistry 20020101

Title: Tropane alkaloid biosynthesis. A century old problem unresolved.

Journal: Natural product reports 20011001

Title: Bedewitz MA, et al.  Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization. Nat Commun. 2018 Dec 11;9(1):5281. doi: 10.1038/s41467-018-07671-3.

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SDS
Tags:532-24-1 Molecular Formula|532-24-1 MDL|532-24-1 SMILES|532-24-1 (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-one |Organic_Building_Blocks