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5352-74-9,MFCD00871167
Catalog No.:AA00DF46

5352-74-9 | 9,13-Di-cis-retinoic acid

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1mg
3 weeks  
$680.00   $476.00
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10mg
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$4,153.00   $2,907.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00DF46
Chemical Name:
9,13-Di-cis-retinoic acid
CAS Number:
5352-74-9
Molecular Formula:
C20H28O2
Molecular Weight:
300.4351
MDL Number:
MFCD00871167
SMILES:
C/C(=C/C=C/C(=C\C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
Properties
Computed Properties
 
Complexity:
567  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
6.3  

Literature

Title: Divergent teratogenicity of agonists of retinoid X receptors in embryos of zebrafish (Danio rerio).

Journal: Ecotoxicology (London, England) 20120701

Title: Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial.

Journal: The British journal of dermatology 20080401

Title: Regulation of 5'-promoter activity of the rat growth hormone and growth hormone-releasing hormone receptor genes in the MtT/S and MtT/E cells.

Journal: Neuroendocrinology 20060101

Title: WY-14643 and 9- cis-retinoic acid induce IRS-2/PI 3-kinase signalling pathway and increase glucose transport in human skeletal muscle cells: differential effect in myotubes from healthy subjects and Type 2 diabetic patients.

Journal: Diabetologia 20040701

Title: Effects of 9-cis- and all-trans-retinoic acids on blood glucose homeostasis in the fiddler crab, Uca pugilator.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101

Title: Retinoids and cancer: antitumoral effects of ATRA, 9-cis RA and the new retinoid IIF on the HL-60 leukemic cell line.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20030101

Title: Cancer studies explore targeted therapy, researchers seek new prevention strategies.

Journal: JAMA 20020619

Title: Biological effects and metabolism of 9-cis-retinoic acid and its metabolite 9,13-di-cis-retinoic acid in HaCaT keratinocytes in vitro: comparison with all-trans-retinoic acid.

Journal: Archives of dermatological research 20001201

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