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550-33-4,MFCD00022819
Catalog No.:AA00DENE

550-33-4 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)oxolane-3,4-diol

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Purity
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25mg
98%
in stock  
$23.00   $16.00
- +
100mg
98%
in stock  
$61.00   $43.00
- +
250mg
98%
in stock  
$133.00   $93.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DENE
Chemical Name:
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)oxolane-3,4-diol
CAS Number:
550-33-4
Molecular Formula:
C10H12N4O4
Molecular Weight:
252.2267
MDL Number:
MFCD00022819
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2
Properties
Properties
 
Form:
Solid  
MP:
173 - 175°C  
Storage:
-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
308  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.7  

Literature

Title: Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.

Journal: European journal of medicinal chemistry 20120101

Title: Diacarperoxide S, new norterpene cyclic peroxide from the sponge Diacarnus megaspinorhabdosa.

Journal: Natural product communications 20120101

Title: Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus.

Journal: Journal of medicinal chemistry 20110414

Title: Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.

Journal: Journal of medicinal chemistry 20110113

Title: Modulation of AMP deaminase in rat hearts subjected to ischemia and reperfusion by purine riboside.

Journal: Nucleosides, nucleotides & nucleic acids 20080601

Title: Isolation and biochemical characterization of delta-aminolevulinic acid dehydratase from Streptomyces yokosukanensis ATCC 25520.

Journal: Prikladnaia biokhimiia i mikrobiologiia 20080101

Title: Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site.

Journal: Biochimica et biophysica acta 20071201

Title: Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius.

Journal: Journal of natural products 20070201

Title: Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.

Journal: Nature structural & molecular biology 20060201

Title: Cytokinins inhibit epiphyllous plantlet development on leaves of Bryophyllum (Kalanchoë) marnierianum.

Journal: Journal of experimental botany 20060101

Title: Binding of MutS mismatch repair protein to DNA containing UV photoproducts, 'mismatched' opposite Watson--Crick and novel nucleotides, in different DNA sequence contexts.

Journal: DNA repair 20050815

Title: Electrochemical detection of lesions in DNA.

Journal: Bioconjugate chemistry 20050101

Title: Human UP1 as a model for understanding purine recognition in the family of proteins containing the RNA recognition motif (RRM).

Journal: Journal of molecular biology 20040917

Title: Synthesis and biological evaluation of 6-substituted purine and 9-beta-d-ribofuranosyl purine analogues.

Journal: Bioorganic & medicinal chemistry 20040315

Title: The assignment of downfield proton resonances in an enzyme inhibitor complex using time-dependent saturation transferred NOEs.

Journal: Journal of the American Chemical Society 20040225

Title: Substrate analogues for an RNA-editing adenosine deaminase: mechanistic investigation and inhibitor design.

Journal: Journal of the American Chemical Society 20030910

Title: Involvement of gibberellin and cytokinin in the formation of embryogenic cell clumps in carrot (Daucus carota).

Journal: Journal of plant physiology 20030201

Title: [Purine nucleoside phosphorylase (PNP)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030101

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.

Journal: Journal of medicinal chemistry 19990826

Title: Synthesis, antiproliferative and antiviral activity of imidazo[4,5-d]isothiazole nucleosides as 5:5 fused analogs of nebularine and 6-methylpurine ribonucleoside.

Journal: Journal of medicinal chemistry 19970227

Title: New hypoxanthine nucleosides with RNA antiviral activity.

Journal: Antiviral research 19920801

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SDS
Tags:550-33-4 Molecular Formula|550-33-4 MDL|550-33-4 SMILES|550-33-4 (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)oxolane-3,4-diol