Title: Novel miRNA biomarkers for genotoxicity screening in mouse.
Journal: Toxicology 20180701
Title: Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
Journal: Toxicology and applied pharmacology 20180601
Title: Glycyrrhizin and glycyrrhetinic acid inhibits alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption.
Journal: Toxicology 20170701
Title: Role of the lipid-regulated NF-κB/IL-6/STAT3 axis in alpha-naphthyl isothiocyanate-induced liver injury.
Journal: Archives of toxicology 20170501
Title: Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis.
Journal: Toxicology 20170215
Title: Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.
Journal: Archives of toxicology 20170101
Title: Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.
Journal: Archives of toxicology 20170101
Title: Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.
Journal: Toxicology letters 20161130
Title: Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice.
Journal: Toxicology and applied pharmacology 20160901
Title: Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.
Journal: Toxicology 20160831
Title: Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats.
Journal: Toxicology and applied pharmacology 20160815
Title: Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.
Journal: Chemico-biological interactions 20160805
Title: Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease.
Journal: Toxicology 20160715
Title: Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism.
Journal: Blood 20160602
Title: Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
Journal: Chemical research in toxicology 20160321
Title: Onset of hepatocarcinogen-specific cell proliferation and cell cycle aberration during the early stage of repeated hepatocarcinogen administration in rats.
Journal: Journal of applied toxicology : JAT 20160201
Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601
Title: Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.
Journal: Toxicology and applied pharmacology 20150315
Title: Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms.
Journal: Acta pharmacologica Sinica 20141201
Title: Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.
Journal: Toxicology 20141105
Title: Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.
Journal: Toxicology 20141003
Title: The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury.
Journal: The Journal of pharmacology and experimental therapeutics 20140601
Title: Metabolomic analysis of arginine metabolism in acute hepatic injury in rats.
Journal: The Journal of toxicological sciences 20140201
Title: Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.
Journal: Toxicology letters 20140103
Title: Systems level analysis and identification of pathways and networks associated with liver fibrosis.
Journal: PloS one 20140101
Title: Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies.
Journal: Journal of applied toxicology : JAT 20131001
Title: Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats.
Journal: Toxicologic pathology 20130701
Title: Expression patterns of cell cycle proteins in the livers of rats treated with hepatocarcinogens for 28 days.
Journal: Archives of toxicology 20130601
Title: Loss of A(1) adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130101
Title: Changes of pharmacokinetics of 6,7-dimethoxycoumarin in a rat model of alpha-naphthylisothiocyanate-induced experimental hepatic injury after Yinchenhao Decoction () treatment.
Journal: Chinese journal of integrative medicine 20121101
Title: Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats.
Journal: Peptides 20120701
Title: Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity.
Journal: Toxicology and applied pharmacology 20120601
Title: Genetic Variations in TXNRD1 as Potential Predictors of Drug-Induced Liver Injury.
Journal: Allergy, asthma & immunology research 20120501
Title: Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120401
Title: Protective effect of Danning tablet on acute livery injury with cholestasis induced by α-naphthylisothiocyanate in rats.
Journal: Journal of ethnopharmacology 20120327
Title: Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301
Title: Mechanism of exacerbative effect of progesterone on drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301
Title: Comparative pharmacokinetic study of paeoniflorin and albiflorin after oral administration of Radix Paeoniae Rubra in normal rats and the acute cholestasis hepatitis rats.
Journal: Fitoterapia 20120301
Title: Effect of alpha-naphthylisothiocyanate-induced liver injury on intestinal adaptation in a rat model of short bowel syndrome.
Journal: Pediatric surgery international 20120201
Title: Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.
Journal: Gastroenterology 20120201
Title: Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120101
Title: Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.
Journal: PloS one 20120101
Title: Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis.
Journal: Archives of toxicology 20111201
Title: Pathogenesis of primary sclerosing cholangitis.
Journal: Best practice & research. Clinical gastroenterology 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: 1-[(Ferrocen-1-yl)meth-yl]-3-(naphthalen-1-yl)thio-urea.
Journal: Acta crystallographica. Section E, Structure reports online 20111201
Title: Immunohistochemical characterization of macrophages and myofibroblasts in α-Naphthylisothiocyanate (ANIT)--induced bile duct injury and subsequent fibrogenesis in rats.
Journal: Toxicologic pathology 20110801
Title: Evaluation study on urine metabolomics in yinhuang rat model induced by triplet factors of rhubarb, ethanol, and α-nephthylisothiolyanate.
Journal: Chinese journal of integrative medicine 20110501
Title: Fibrosis in autoimmune and cholestatic liver disease.
Journal: Best practice & research. Clinical gastroenterology 20110401
Title: Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis.
Journal: The American journal of pathology 20110301
Title: Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.
Journal: Toxicology and applied pharmacology 20110201
Title: Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110101
Title: Measuring size-dependent permeability of the tight junction using PEG profiling.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Hepatotoxicity or hepatoprotection? Pattern recognition for the paradoxical effect of the Chinese herb Rheum palmatum L. in treating rat liver injury.
Journal: PloS one 20110101
Title: Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver.
Journal: PloS one 20110101
Title: Protective effects of Moutan Cortex Radicis against acute hepatotoxicity.
Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.
Journal: The American journal of pathology 20101201
Title: Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice.
Journal: Toxicology 20100910
Title: Time course gene expression using laser capture microscopy-extracted bile ducts, but not hepatic parenchyma, reveals acute alpha-naphthylisothiocyanate toxicity.
Journal: Toxicologic pathology 20100801
Title: Acute ANIT toxicity in male IL-10 knockout and wild-type mice.
Journal: Toxicologic pathology 20100801
Title: Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats.
Journal: Die Pharmazie 20100701
Title: Metabolic Fingerprinting in Toxicological Assessment Using FT-ICR MS.
Journal: Journal of toxicologic pathology 20100601
Title: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100501
Title: Evaluation of a liver micronucleus assay in young rats (III): a study using nine hepatotoxicants by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS).
Journal: Mutation research 20100430
Title: [Effect of emodin on P-gp expression in intrahepatic cholestatic rats].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401
Title: Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis.
Journal: Basic & clinical pharmacology & toxicology 20090901
Title: Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701
Title: Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation.
Journal: Hepatology (Baltimore, Md.) 20090701
Title: Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.
Journal: Basic & clinical pharmacology & toxicology 20090601
Title: Comparative study on the protective effects of Yinchenhao Decoction against liver injury induced by alpha-naphthylisothiocyanate and carbon tetrachloride.
Journal: Chinese journal of integrative medicine 20090601
Title: Quantitative analysis of valiolamine through pre-column derivatization with phenylisocyanate using high-performance liquid chromatography with UV detection: selection of reagent, identification of derivative and optimization of derivatization conditions.
Journal: Journal of pharmaceutical and biomedical analysis 20090501
Title: [Effect and mechanism of emodin on cholestatic hepatitis].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090501
Title: Characterization of the enhancing effect of protamine on the proliferative activity of hepatocyte growth factor in rat hepatocytes.
Journal: Pharmaceutical research 20090401
Title: Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090401
Title: ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090401
Title: Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin.
Journal: Human & experimental toxicology 20090401
Title: [Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats].
Journal: Zhonghua yi xue za zhi 20090317
Title: The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability.
Journal: Environmental health : a global access science source 20090101
Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.
Journal: PloS one 20090101
Title: Raman spectral signatures of human liver perfusates correlate with oxidation reduction potential.
Journal: Molecular medicine reports 20090101
Title: Monitoring healthy metabolic trajectories with nutritional metabonomics.
Journal: Nutrients 20090101
Title: Modulation of the inflammatory response and apoptosis using epidermal growth factor and hepatocyte growth factor in a liver injury model: a potential approach to the management and treatment of cholestatic liver disease.
Journal: Journal of pediatric surgery 20081201
Title: Bile acids metabonomic study on the CCl4- and alpha-naphthylisothiocyanate-induced animal models: quantitative analysis of 22 bile acids by ultraperformance liquid chromatography-mass spectrometry.
Journal: Chemical research in toxicology 20081201
Title: Urinary metabolic fingerprinting for alpha-naphthylisothiocyanate-induced intrahepatic cholestasis in rats using Fourier transform-ion cyclotron resonance mass spectrometry.
Journal: Toxicologic pathology 20081001
Title: In vivo effect of selective macrophage suppression on the development of intrahepatic cholestasis in mice.
Journal: Bulletin of experimental biology and medicine 20081001
Title: Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway.
Journal: European journal of pharmacology 20080820
Title: A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.
Journal: Toxicology 20080819
Title: Activity of lysosomal enzymes in the bile and serum of mice with intrahepatic cholestasis.
Journal: Bulletin of experimental biology and medicine 20080501
Title: Validation of putative genomic biomarkers of nephrotoxicity in rats.
Journal: Toxicology 20080418
Title: Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080401
Title: Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080401
Title: [Role of early growth response factor-1 signal pathway in acute intrahepatic cholestatic hepatic injury in rats].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080301
Title: Hepatoprotective effect of Hypericum japonicum extract and its fractions.
Journal: Journal of ethnopharmacology 20080227
Title: Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide.
Journal: European journal of pharmacology 20080212
Title: Integrative top-down system metabolic modeling in experimental disease states via data-driven Bayesian methods.
Journal: Journal of proteome research 20080201
Title: Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080120
Title: Piecewise multivariate modelling of sequential metabolic profiling data.
Journal: BMC bioinformatics 20080101
Title: A CD133-expressing murine liver oval cell population with bilineage potential.
Journal: Stem cells (Dayton, Ohio) 20071001
Title: Acute hepatotoxicity: a predictive model based on focused illumina microarrays.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901
Title: Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701
Title: Bone marrow fails to differentiate into liver epithelium during murine development and regeneration.
Journal: Hepatology (Baltimore, Md.) 20070501
Title: Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070301
Title: Melatonin attenuates disruption of serum cholesterol status in rats with a single alpha-naphthylisothiocyanate treatment.
Journal: Journal of pineal research 20070301
Title: Ketoprofen glucuronidation and bile excretion in carbon tetrachloride and alpha-naphthylisothiocyanate induced hepatic injury rats.
Journal: Toxicology 20070212
Title: Protective effect of glycyrrhizin, glycyrrhetic acid and matrine on acute cholestasis induced by alpha-naphthyl isothiocyanate in rats.
Journal: Planta medica 20070201
Title: Protective effect of glycyrrhizin and matrine on acute vanishing bile duct syndrome induced by alpha-naphthylisothiocyanate in rats.
Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20070201
Title: Determination and kinetics of producing glucosamine using fungi.
Journal: Biotechnology progress 20070101
Title: Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue.
Journal: Journal of clinical biochemistry and nutrition 20070101
Title: Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060901
Title: ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060801
Title: Heterogeneity of the intrahepatic biliary epithelium.
Journal: World journal of gastroenterology 20060614
Title: alpha-Tocopherol protects against alpha-naphthylisothiocyanate-induced hepatotoxicity in rats less effectively than melatonin.
Journal: Chemico-biological interactions 20060610
Title: Lack of evidence that bone marrow cells contribute to cholangiocyte repopulation during experimental cholestatic ductal hyperplasia.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20060501
Title: Analysis of kanamycin A in human plasma and in oral dosage form by derivatization with 1-naphthyl isothiocyanate and high-performance liquid chromatography.
Journal: Journal of separation science 20060301
Title: The potential risks of nanomaterials: a review carried out for ECETOC.
Journal: Particle and fibre toxicology 20060101
Title: Characterization of ANIT-induced toxicity using precision-cut rat and dog liver slices cultured in a dynamic organ roller system.
Journal: Toxicologic pathology 20060101
Title: Liquid chromatography-mass spectrometric analysis of urinary metabolites and their pattern recognition for the prediction of drug-induced hepatotoxicity.
Journal: Chemical research in toxicology 20051201
Title: NMR spectroscopic-based metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats.
Journal: Journal of inorganic biochemistry 20051101
Title: Pharmacokinetics of alpha-naphthyl isothiocyanate in rats.
Journal: Journal of pharmaceutical sciences 20051101
Title: Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
Journal: Clinical chemistry 20051001
Title: Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.
Journal: Journal of biotechnology 20050929
Title: Chemometric analysis of biofluids following toxicant induced hepatotoxicity: a metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050801
Title: Comparison of murine cirrhosis models induced by hepatotoxin administration and common bile duct ligation.
Journal: World journal of gastroenterology 20050721
Title: Limited protective role of V-PYRRO/NO against cholestasis produced by alpha-naphthylisothiocyanate in mice.
Journal: Biochemical pharmacology 20050701
Title: Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis.
Journal: Journal of gastroenterology and hepatology 20050701
Title: Effect of alpha-naphthyl isothiocyanate on 2-amino-3-methylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in rats.
Journal: International journal of cancer 20050620
Title: Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501
Title: Comparison of metabolic profiles from serum from hepatotoxin-treated rats by nuclear-magnetic-resonance-spectroscopy-based metabonomic analysis.
Journal: Analytical biochemistry 20050501
Title: Studies on the acute biochemical effects of La(NO3)3 using 1H NMR spectroscopy of urine combined with pattern recognition.
Journal: Journal of inorganic biochemistry 20050201
Title: Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine.
Journal: Life sciences 20050128
Title: Effects of alpha-naphthyl isothiocyanate and a heterocyclic amine, PhIP, on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver.
Journal: Mutagenesis 20050101
Title: In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid.
Journal: Journal of medicinal food 20050101
Title: Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040901
Title: Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines.
Journal: Experimental biology and medicine (Maywood, N.J.) 20040901
Title: Discriminating different classes of toxicants by transcript profiling.
Journal: Environmental health perspectives 20040801
Title: Effects of benzyl-, phenethyl-, and alpha-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport.
Journal: Journal of pharmaceutical sciences 20040701
Title: Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.
Journal: Biochemical pharmacology 20040601
Title: Development of a LC-MS/MS method for the analysis of volatile primary and secondary amines as NIT (naphthylisothiocyanate) derivatives.
Journal: Analytical and bioanalytical chemistry 20040201
Title: Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status.
Journal: Archives of toxicology 20040201
Title: Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
Title: [6,8-Dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-f]xanthine: a new inductor of the monooxygenase system inhibits experimental intrahepatic cholestasis in rats].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101
Title: Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Journal: The Journal of clinical investigation 20031201
Title: Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031001
Title: Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats.
Journal: Proteomics 20031001
Title: Assessment of hepatocytes and liver slices as in vitro test systems to predict in vivo gene expression.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030901
Title: Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis.
Journal: Gut 20030901
Title: Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).
Journal: Toxicology 20030828
Title: Glutathione depletion exacerbates methylenedianiline toxicity to biliary epithelial cells and hepatocytes in rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030801
Title: A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum.
Journal: The Analyst 20030701
Title: Determination of alpha-naphthylisothiocyanate and metabolites alpha-naphthylamine and alpha-naphthylisocyanate in rat plasma and urine by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Title: Preventive effect of melatonin on the progression of alpha-naphthylisothiocyanate-induced acute liver injury in rats.
Journal: Journal of pineal research 20030401
Title: Hepatic artery and portal vein remodeling in rat liver: vascular response to selective cholangiocyte proliferation.
Journal: The American journal of pathology 20030401
Title: Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.
Journal: Archives of toxicology 20030401
Title: An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria.
Journal: Archives of toxicology 20030401
Title: Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20030301
Title: Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?
Journal: Biochimica et biophysica acta 20030120
Title: Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?
Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20030101
Title: Cholestasis: human disease and experimental animal models.
Journal: Annals of hepatology 20030101
Title: Trace analysis of tobramycin in human plasma by derivatization and high-performance liquid chromatography with ultraviolet detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125
Title: Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine.
Journal: Pharmaceutical research 20021001
Title: Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.
Journal: Bulletin of experimental biology and medicine 20020901
Title: Functional heterogeneity of cholangiocytes.
Journal: Seminars in liver disease 20020801
Title: NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate.
Journal: Biochemical pharmacology 20020701
Title: Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.
Journal: Toxicology and applied pharmacology 20020701
Title: Experimental colitis attenuates development of toxin-induced cholangitis in rats.
Journal: Digestive diseases and sciences 20020601
Title: Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020501
Title: Preventive effect of the Taiwan folk medicine Ixeris laevigata var. oldhami on alpha-naphthyl-isothiocyanate and carbon tetrachloride-induced acute liver injury in rats.
Journal: Phytotherapy research : PTR 20020301
Title: Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data.
Journal: The Analyst 20020201
Title: Alpha-glutathione S-transferase in the assessment of hepatotoxicity--its diagnostic utility in comparison with other recognized markers in the Wistar Han rat.
Journal: Toxicologic pathology 20020101
Title: High performance liquid chromatographic determination of glucosamine in rat plasma.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101
Title: Prophylactic effect of four prescriptions of traditional Chinese medicine on alpha-naphthylisothiocyanate and carbon tetrachloride induced toxicity in rats.
Journal: Acta pharmacologica Sinica 20011201
Title: Effect of melatonin on changes in hepatic antioxidant enzyme activities in rats treated with alpha-naphthylisothiocyanate.
Journal: Journal of pineal research 20011101
Title: Role of MRP2 and GSH in intrahepatic cycling of toxins.
Journal: Toxicology 20011005
Title: NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach.
Journal: Chemical research in toxicology 20011001
Title: Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20010701
Title: Quantitative assessment of the rat intrahepatic biliary system by three-dimensional reconstruction.
Journal: The American journal of pathology 20010601
Title: [Study on hepatic-protective effect of 'yinzhihuang' granula].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010501
Title: Regulation of cholangiocyte proliferation.
Journal: Liver 20010401
Title: Determination of morpholine in air by derivatisation with 1-naphthylisothiocyanate and HPLC analysis.
Journal: The Analyst 20010201
Title: Characterization of the protective effects of melatonin and related indoles against alpha-naphthylisothiocyanate-induced liver injury in rats.
Journal: Journal of cellular biochemistry 20010101
Title: Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20001001
Title: ANIT-induced disruption of biliary function in rat hepatocyte couplets.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 19990201
Title: Cytotoxicity of naphthylisothiocyanates in rat hepatocyte-neutrophil cocultures.
Journal: Toxicology letters 19980501
Title: Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.
Journal: Biochemical pharmacology 19951026
Title: Leukotrienes and alpha-naphthylisothiocyanate-induced liver injury.
Journal: Toxicology 19950626
Title: Cholestatic potentials of alpha-naphthylisothiocyanate (ANIT) and beta-naphthylisothiocyanate (BNIT) in the isolated perfused rat liver.
Journal: Biochemical pharmacology 19931203
Title: Lack of benefit of ursodeoxycholic acid in drug-induced cholestasis in the rat.
Journal: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19920501
Title: Relationship between alpha-naphthylisothiocyanate-induced liver injury and elevations in hepatic non-protein sulfhydryl content.
Journal: Biochemical pharmacology 19910822
Title: Increased paracellular permeability in intrahepatic cholestasis induced by carmustine (BCNU) in rats.
Journal: Gastroenterology 19910701
Title: Drug-induced intrahepatic cholestasis: characterization of different pathomechanisms.
Journal: Archives of toxicology 19870101
Title: Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds.
Journal: Chemico-biological interactions 19870101
Title: No increase of biliary permeability in ethinylestradiol-treated rats.
Journal: Gastroenterology 19831001
Title: Effect of various factors on the induction of liver tumors in animals by quinoline.
Journal: Gan 19771201
