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56-35-9,MFCD00009418
Catalog No.:AA003O9O

56-35-9 | Bis(Tributyltin) Oxide

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Purity
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1g
95%
in stock  
$18.00   $13.00
- +
25g
96%
in stock  
$77.00   $54.00
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100g
96%
in stock  
$118.00   $83.00
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500g
96%
in stock  
$247.00   $173.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003O9O
Chemical Name:
Bis(Tributyltin) Oxide
CAS Number:
56-35-9
Molecular Formula:
C24H54OSn2
Molecular Weight:
596.0870
MDL Number:
MFCD00009418
SMILES:
CCCC[Sn](O[Sn](CCCC)(CCCC)CCCC)(CCCC)CCCC
Properties
Properties
 
BP:
180 °C  
Form:
Liquid  
MP:
-45°C  
Refractive Index:
n20/D 1.486(lit.)  
Stability:
Air & Moisture Sensitive  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
246  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
20  

Literature

Title: Inhibition of CXCL12-mediated chemotaxis of Jurkat cells by direct immunotoxicants.

Journal: Archives of toxicology 20160701

Title: A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Journal: Archives of toxicology 20151201

Title: Oxidative Stress Mechanisms Do Not Discriminate between Genotoxic and Nongenotoxic Liver Carcinogens.

Journal: Chemical research in toxicology 20150817

Title: The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism.

Journal: Journal of applied toxicology : JAT 20141201

Title: Transcriptome-based functional classifiers for direct immunotoxicity.

Journal: Archives of toxicology 20140301

Title: DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells.

Journal: Toxicology letters 20140130

Title: Toxicogenomics-based identification of mechanisms for direct immunotoxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131001

Title: Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics.

Journal: Toxicology letters 20130213

Title: Immunocytological and biochemical analysis of the mode of action of bis (tri-n-butyltin) tri-oxide (TBTO) in Jurkat cells.

Journal: Toxicology letters 20120720

Title: Transcriptomics analysis of primary mouse thymocytes exposed to bis(tri-n-butyltin)dioxide (TBTO).

Journal: Toxicology 20120614

Title: Monitoring the performance of innovative and traditional biocides mixed with consolidants and water-repellents for the prevention of biological growth on stone.

Journal: The Science of the total environment 20120415

Title: Phosphoproteomic analysis of mouse thymoma cells treated with tributyltin oxide: TBTO affects proliferation and energy sensing pathways.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301

Title: Exposure of Jurkat cells to bis (tri-n-butyltin) oxide (TBTO) induces transcriptomics changes indicative for ER- and oxidative stress, T cell activation and apoptosis.

Journal: Toxicology and applied pharmacology 20110801

Title: The inducibility of human cytochrome P450 1A by environmental-relevant xenobiotics in the human hepatoma derived cell line HepG2.

Journal: Environmental toxicology and pharmacology 20091101

Title: Proteomic analysis of mouse thymoma EL4 cells treated with bis(tri-n-butyltin)oxide (TBTO).

Journal: Journal of immunotoxicology 20090901

Title: Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.

Journal: Toxicology and applied pharmacology 20080101

Title: Bis(tributyltin)oxide (TBTO) decreases the food allergic response against peanut and ovalbumin in Brown Norway rats.

Journal: Toxicology 20070924

Title: In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics.

Journal: Toxicology 20070731

Title: Cytotoxic effects and aromatase inhibition by xenobiotic endocrine disrupters alone and in combination.

Journal: Toxicology and applied pharmacology 20070715

Title: Phototactic behavior in Daphnia magna Straus as an indicator of toxicants in the aquatic environment.

Journal: Ecotoxicology and environmental safety 20070701

Title: Molecular and histological evaluation of tributyltin toxicity on spermatogenesis in a marine fish, the mummichog (Fundulus heteroclitus).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070605

Title: Effects of various pesticides on human 5alpha-reductase activity in prostate and LNCaP cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070401

Title: Gene expression profiling of Bis(tri-n-butyltin)oxide (TBTO)-induced immunotoxicity in mice and rats.

Journal: Journal of immunotoxicology 20061201

Title: The comparative immunotoxicity of five selected compounds following developmental or adult exposure.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20060101

Title: 5,6-Dichloro-1-methylgramine, a non-toxic antifoulant derived from a marine natural product.

Journal: Progress in molecular and subcellular biology 20060101

Title: Use of the local lymph node assay in assessment of immune function.

Journal: Toxicology 20050701

Title: Detection of immunotoxicity using T-cell based cytokine reporter cell lines ('Cell Chip').

Journal: Toxicology 20050115

Title: Effects of antifouling paint components (TBTO, copper and triazine) on the early development of embryos in cod (Gadus morhua L.).

Journal: Marine pollution bulletin 20021001

Title: Neurotoxicologic sequelae of tributyltin intoxication in rats.

Journal: Pharmacological research 20020301

Title: Toxicology of environmental chemicals in the flounder (Platichthys flesus) with emphasis on the immune system: field, semi-field (mesocosm) and laboratory studies.

Journal: Toxicology letters 20000315

Title: In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes.

Journal: Toxicology 19990701

Title: Effects of in vivo exposure to bis(tri-n-butyltin)oxide, hexachlorobenzene, and benzo(a)pyrene on cytokine (receptor) mRNA levels in cultured rat splenocytes and on IL-2 receptor protein levels.

Journal: Toxicology and applied pharmacology 19980101

Title: Acute effect of indoor exposure to paint containing bis(tributyltin) oxide--Wisconsin, 1991.

Journal: MMWR. Morbidity and mortality weekly report 19910503

Title: Evaluation of the genetic and embryotoxic effects of bis(tri-n-butyltin)oxide (TBTO), a broad-spectrum pesticide, in multiple in vivo and in vitro short-term tests.

Journal: Mutation research 19870601

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