Title: Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency.
Journal: Bioorganic & medicinal chemistry letters 20120115
Title: Identification of novel sildenafil-analogues in an adulterated herbal food supplement.
Journal: Journal of pharmaceutical and biomedical analysis 20111205
Title: Discovery of potent, orally bioavailable phthalazinone bradykinin B1 receptor antagonists.
Journal: Journal of medicinal chemistry 20111027
Title: Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.
Journal: Bioorganic & medicinal chemistry letters 20110615
Title: 3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation.
Journal: Bioorganic & medicinal chemistry letters 20110601
Title: A submarine journey: the pyrrole-imidazole alkaloids.
Journal: Marine drugs 20091201
Title: Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity.
Journal: BMC bioinformatics 20090101
Title: Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.
Journal: Journal of asthma and allergy 20090101
Title: Computer applications for prediction of protein-protein interactions and rational drug design.
Journal: Advances and applications in bioinformatics and chemistry : AABC 20090101
Title: Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
Journal: Journal of medicinal chemistry 20081009
Title: Concise synthesis of the CDE ring system of tetrahydroisoquinoline alkaloids using carbophilic Lewis acid-catalyzed hydroamidation and oxidative Friedel-Crafts cyclization.
Journal: The Journal of organic chemistry 20080704
Title: Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.
Journal: Bioorganic & medicinal chemistry 20080201
Title: [Piperazines as model substrate for oxidations].
Journal: Die Pharmazie 20061001
Title: New class of nucleophiles for palladium-catalyzed asymmetric allylic alkylation. Total synthesis of agelastatin A.
Journal: Journal of the American Chemical Society 20060510
Title: Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I.
Journal: Organic & biomolecular chemistry 20060507
Title: (13)C NMR spectral assignment of 1,4-diarylpiperazinones.
Journal: Magnetic resonance in chemistry : MRC 20060101
Title: Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.
Journal: Chemical & pharmaceutical bulletin 20040401
Title: Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Journal: Bioorganic & medicinal chemistry letters 20040209
Title: Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds.
Journal: Journal of combinatorial chemistry 20040101
Title: alpha-Keto amides as precursors to heterocycles--generation and cycloaddition reactions of piperazin-5-one nitrones.
Journal: Organic & biomolecular chemistry 20030407
Title: Synthesis of 1,4-diazines by ring expansion of 1,3-diazines.
Journal: The Journal of organic chemistry 20030321
Title: Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.
Journal: Journal of medicinal chemistry 20030227
Title: Potent dibasic GPIIb/IIIa antagonists with reduced prolongation of bleeding time: synthesis and pharmacological evaluation of 2-oxopiperazine derivatives.
Journal: Journal of medicinal chemistry 20010719
Title: The design of competitive, small-molecule inhibitors of coagulation factor Xa.
Journal: Current topics in medicinal chemistry 20010601
Title: 3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase.
Journal: Organic letters 20010322
Title: Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.
Journal: Bioorganic & medicinal chemistry letters 20010226
Title: Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20010212
870704-04-4 | 3-(4-Bromophenyl)-1-(4-chlorophenyl)pyrazole-4-propionic acid | AA003I0C | MFCD07784416