Home Other Building Blocks 5625-67-2
5625-67-2,MFCD01318687
Catalog No.:AA003HTE
5625-67-2 | Piperazin-2-one
Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$8.00   $5.00
- +
5g
98%
in stock  
$22.00   $15.00
- +
10g
98%
in stock  
$32.00   $22.00
- +
25g
98%
in stock  
$58.00   $40.00
- +
100g
98%
in stock  
$159.00   $111.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003HTE
Chemical Name:
Piperazin-2-one
CAS Number:
5625-67-2
Molecular Formula:
C4H8N2O
Molecular Weight:
100.1191
MDL Number:
MFCD01318687
IUPAC Name:
piperazin-2-one
InChI:
InChI=1S/C4H8N2O/c7-4-3-5-1-2-6-4/h5H,1-3H2,(H,6,7)
InChI Key:
IWELDVXSEVIIGI-UHFFFAOYSA-N
SMILES:
O=C1CNCCN1
EC Number:
629-162-6
NSC Number:
27441
Properties
Computed Properties
 
Complexity:
81.8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
100.064g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
100.121g/mol
Monoisotopic Mass:
100.064g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
41.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.1  

Synonyms
 
Piperazin-2-one 
5625-67-2 
MFCD01318687 
F1775-0070 
2-piperazone 
2-Piperazinone, 97% 1g 
C4H8N2O 
AR-1E5065 
CID231360 
RW1743 
Piperazin-2-one, 98% - 1G 1g 
ACN-025023 
1098202-37-9 
Piperazine-2-one, 95% 
298705-64-3 
63450-00-0 
keto piperazine 
3-oxopiperazine 
2-ketopiperazine 
piperazin-3-one 
piperizin-2-one 
piperazin-2-on 
2-oxo piperazine 
2-oxo-piperazine 
2-Piperazinone 
2-Piperazine-one 
NSC27441 
PubChem8557 
PubChem23093 
ACMC-1AWJL 
2-Oxopiperazine, 97% 
AC1L5LIV 
AC1Q6ETV 
AC1Q6GYJ 
SCHEMBL5194 
2-Oxopiperazine 
tetrahydro-2(1h)-pyrazinone 
KSC269S6R 
ARONIS020139 
TPC-A001 
CTK1G9968 
KS-00004BXH 
DTXSID10282698 
5625-67-2 piperazin-2-one 
3,4,5,6-tetrahydropyrazin-2-ol 
ALBB-012180 
Piperazine-2-one 
BCP26674 
CS-B0039 
STR07287 
ANW-32474 
BBL023498 
CP0086 
HT1199 
NSC-27441 
SBB000034 
STK025825 
Piperazinone 
STL301724 
ZINC73658704 
AKOS000269318 
AKOS022140684 
AC-1109 
AN-1675 
LS20789 
MCULE-5599978871 
PB23229 
PS-9326 
oxopiperazine 
RP00416 
RP18699 
RTC-063664 
KS-000003O9 
TRA-0205525 
AJ-46543 
AK-26132 
BC204568 
BP-11215 
BR-26132 
2-piperadone 
SC-05365 
ST025752 
SY002559 
AB0009457 
AB1005621 
DB-031180 
ST2419789 
TC-063664 
TL8007328 
4CH-002270 
piperazone 
A8081 
AM20100386 
BB 0218076 
C2503 
FT-0084567 
FT-0649566 
P1867 
M-3661 
P17300 
32673-EP2301933A1 
IWELDVXSEVIIGI-UHFFFAOYSA-N 
32673-EP2311827A1 
43797-EP2298772A1 
43797-EP2308839A1 
43797-EP2311814A1 
80118-EP2272517A1 
80118-EP2305250A1 
MFCD01318687 (97+%) 
625P672 
I13-0059 
W-203124 
Literature

Title: Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Identification of novel sildenafil-analogues in an adulterated herbal food supplement.

Journal: Journal of pharmaceutical and biomedical analysis 20111205

Title: Discovery of potent, orally bioavailable phthalazinone bradykinin B1 receptor antagonists.

Journal: Journal of medicinal chemistry 20111027

Title: Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.

Journal: Bioorganic & medicinal chemistry letters 20110615

Title: 3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation.

Journal: Bioorganic & medicinal chemistry letters 20110601

Title: A submarine journey: the pyrrole-imidazole alkaloids.

Journal: Marine drugs 20091201

Title: Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity.

Journal: BMC bioinformatics 20090101

Title: Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.

Journal: Journal of asthma and allergy 20090101

Title: Computer applications for prediction of protein-protein interactions and rational drug design.

Journal: Advances and applications in bioinformatics and chemistry : AABC 20090101

Title: Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.

Journal: Journal of medicinal chemistry 20081009

Title: Concise synthesis of the CDE ring system of tetrahydroisoquinoline alkaloids using carbophilic Lewis acid-catalyzed hydroamidation and oxidative Friedel-Crafts cyclization.

Journal: The Journal of organic chemistry 20080704

Title: Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.

Journal: Bioorganic & medicinal chemistry 20080201

Title: [Piperazines as model substrate for oxidations].

Journal: Die Pharmazie 20061001

Title: New class of nucleophiles for palladium-catalyzed asymmetric allylic alkylation. Total synthesis of agelastatin A.

Journal: Journal of the American Chemical Society 20060510

Title: Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I.

Journal: Organic & biomolecular chemistry 20060507

Title: (13)C NMR spectral assignment of 1,4-diarylpiperazinones.

Journal: Magnetic resonance in chemistry : MRC 20060101

Title: Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.

Journal: Chemical & pharmaceutical bulletin 20040401

Title: Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds.

Journal: Journal of combinatorial chemistry 20040101

Title: alpha-Keto amides as precursors to heterocycles--generation and cycloaddition reactions of piperazin-5-one nitrones.

Journal: Organic & biomolecular chemistry 20030407

Title: Synthesis of 1,4-diazines by ring expansion of 1,3-diazines.

Journal: The Journal of organic chemistry 20030321

Title: Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.

Journal: Journal of medicinal chemistry 20030227

Title: Potent dibasic GPIIb/IIIa antagonists with reduced prolongation of bleeding time: synthesis and pharmacological evaluation of 2-oxopiperazine derivatives.

Journal: Journal of medicinal chemistry 20010719

Title: The design of competitive, small-molecule inhibitors of coagulation factor Xa.

Journal: Current topics in medicinal chemistry 20010601

Title: 3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase.

Journal: Organic letters 20010322

Title: Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase.

Journal: Bioorganic & medicinal chemistry letters 20010226

Title: Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20010212

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