Home Thiazoles 56278-50-3
56278-50-3,MFCD00051633
Catalog No.:AA003O01

56278-50-3 | Benzothiazole-2-acetonitrile

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$11.00   $8.00
- +
5g
95%
in stock  
$13.00   $9.00
- +
25g
95%
in stock  
$55.00   $39.00
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100g
95%
in stock  
$218.00   $153.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003O01
Chemical Name:
Benzothiazole-2-acetonitrile
CAS Number:
56278-50-3
Molecular Formula:
C9H6N2S
Molecular Weight:
174.2223
MDL Number:
MFCD00051633
SMILES:
N#CCc1nc2c(s1)cccc2
NSC Number:
379416
Properties
Properties
 
BP:
329.6°C at 760 mmHg  
Form:
Solid  
MP:
98-101 °C(lit.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
208  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
2.3  

Literature

Title: Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress.

Journal: PloS one 20120101

Title: Synthesis, characterization of some benzazoles bearing pyridine moiety: search for novel anticancer agents.

Journal: European journal of medicinal chemistry 20110901

Title: Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation.

Journal: Journal of neuroinflammation 20110101

Title: Solvatochromic, acid-base features and time effect of some azo dyes derived from 1,3-benzothiazol-2-ylacetonitrile: experimental and semiempirical investigations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100201

Title: FoxO and stress responses in the cnidarian Hydra vulgaris.

Journal: PloS one 20100101

Title: Three-dimensional quantitative structure-activity relationship (3 D-QSAR) and docking studies on (benzothiazole-2-yl) acetonitrile derivatives as c-Jun N-terminal kinase-3 (JNK3) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20061115

Title: Exploration of a binding mode of benzothiazol-2-yl acetonitrile pyrimidine core based derivatives as potent c-Jun N-terminal kinase-3 inhibitors and 3D-QSAR analyses.

Journal: Journal of chemical information and modeling 20060101

Title: Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase.

Journal: Journal of medicinal chemistry 20050714

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