Home Other Building Blocks 56293-29-9
56293-29-9,MFCD00468086
Catalog No.:AA003NO4

56293-29-9 | Aloperine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
100mg
98%
in stock  
$41.00   $29.00
- +
250mg
98%
in stock  
$82.00   $57.00
- +
500mg
≥95%
in stock  
$93.00   $65.00
- +
1g
≥95%
in stock  
$173.00   $121.00
- +
5g
95%
in stock  
$760.00   $532.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003NO4
Chemical Name:
Aloperine
CAS Number:
56293-29-9
Molecular Formula:
C15H24N2
Molecular Weight:
232.3645
MDL Number:
MFCD00468086
SMILES:
C1CCC2N(C1)CC1CC2C=C2C1NCCC2
Properties
Properties
 
BP:
367.7°C at 760 mmHg  
Form:
Solid  
MP:
67 - 69°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
336  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.6  

Downstream Synthesis Route
106-95-6    56293-29-9   
(+)-N-allylaloperine 

[1]JournaloftheAmericanChemicalSociety,1999,vol.121,p.700-709

[1]JournaloftheAmericanChemicalSociety,1999,vol.121,p.700-709

[1]JournaloftheAmericanChemicalSociety,1999,vol.121,p.700-709

[1]TetrahedronAsymmetry,2004,vol.15,p.2921-2925

Literature

Title: Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors.

Journal: ACS medicinal chemistry letters 20171109

Title: Aloperine and Its Derivatives as a New Class of HIV-1 Entry Inhibitors.

Journal: ACS medicinal chemistry letters 20160310

Title: [Simultaneous determination of 7 alkaloid in herba Sophorae Alopecuroidis by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

Title: Topical application of aloperine improves 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice.

Journal: European journal of pharmacology 20110511

Title: In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait.

Journal: Basic & clinical pharmacology & toxicology 20110501

Title: Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice.

Journal: European journal of pharmacology 20100310

Title: [Constituents in the alkaloid fraction of Kushen decoction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

Title: Synthesis of an optically pure synthetic intermediate of aloperine from a yeast-reductive product.

Journal: Bioscience, biotechnology, and biochemistry 20050801

Title: [Effects of isoprenaline on apoptosis related gene expression in rat myocardium cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20001101

Title: Lin Z, et al. In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait. Basic Clin Pharmacol Toxicol. 2011 May;108(5):304-9.

Title: Yuan XY, et al. Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice. Eur J Pharmacol. 2010 Mar 10;629(1-3):147-52.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 56293-29-9
Tags:56293-29-9 Molecular Formula|56293-29-9 MDL|56293-29-9 SMILES|56293-29-9 Aloperine