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56392-16-6,MFCD00871829
Catalog No.:AA00EBTG

56392-16-6 | ALPHA-HYDROXYMETOPROLOL

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Purity
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Price(USD)
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1mg
≥95%
in stock  
$130.00   $91.00
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5mg
≥95%
in stock  
$326.00   $228.00
- +
10mg
≥95%
in stock  
$520.00   $364.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EBTG
Chemical Name:
ALPHA-HYDROXYMETOPROLOL
CAS Number:
56392-16-6
Molecular Formula:
C15H25NO4
Molecular Weight:
283.3633
MDL Number:
MFCD00871829
SMILES:
CC(C)NCC(COC1=CC=C(C=C1)C(COC)O)O
Properties
Properties
 
Form:
Solid  
MP:
65-67°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
242  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
2  
XLogP3:
0.3  

Literature

Title: Mineralization of metoprolol by electro-Fenton and photoelectro-Fenton processes.

Journal: The journal of physical chemistry. A 20110224

Title: Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090601

Title: Influence of CYP2D6*10 on the pharmacokinetics of metoprolol in healthy Korean volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20081001

Title: Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).

Journal: European journal of clinical pharmacology 20080301

Title: The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients.

Journal: Journal of clinical pharmacy and therapeutics 20060201

Title: Impact of CYP2D6 genotype on adverse effects during treatment with metoprolol: a prospective clinical study.

Journal: Clinical pharmacology and therapeutics 20051001

Title: Stereoselective analysis of metoprolol and its metabolites in rat plasma with application to oxidative metabolism.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050905

Title: Stereoselective metabolism of metoprolol: enantioselectivity of alpha-hydroxymetoprolol in plasma and urine.

Journal: Chirality 20030601

Title: Effect of the CYP2D6 genotype on metoprolol metabolism persists during long-term treatment.

Journal: Pharmacogenetics 20020801

Title: Influence of input rate on the stereospecific and nonstereospecific first pass metabolism and pharmacokinetics of metoprolol extended release formulations.

Journal: Chirality 20020505

Title: The influence of first pass metabolism on the development and validation of an IVIVC for metoprolol extended release tablets.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020501

Title: Enantiomeric separation of metoprolol and alpha-hydroxymetoprolol by liquid chromatography and fluorescence detection using a chiral stationary phase.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010715

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Tags:56392-16-6 Molecular Formula|56392-16-6 MDL|56392-16-6 SMILES|56392-16-6 ALPHA-HYDROXYMETOPROLOL