Home Deuterated Building Blocks 56973-12-7
56973-12-7,MFCD15145304
Catalog No.:AA00EHIQ

56973-12-7 | 8-methyladenosine

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Purity
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10mg
2 weeks  
$206.00   $144.00
- +
25mg
2 weeks  
$286.00   $200.00
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50mg
2 weeks  
$400.00   $280.00
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100mg
2 weeks  
$672.00   $470.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EHIQ
Chemical Name:
8-methyladenosine
CAS Number:
56973-12-7
Molecular Formula:
C11H15N5O4
Molecular Weight:
281.2679
MDL Number:
MFCD15145304
SMILES:
CC1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N
Properties
Computed Properties
 
Complexity:
362  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-0.6  

Literature

Title: 5'-O-dephosphorylated 2',5'-oligoadenylate (2-5A) with 8-methyladenosine at the 2'-terminus activates human RNase L.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.

Journal: RNA (New York, N.Y.) 20090201

Title: Introduction of 8-methyladenosine into 2', 5'-oligoadenylate (2-5A) 2'-terminus induces dramatic shift in binding site of RNase L.

Journal: Nucleic acids symposium series (2004) 20090101

Title: Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides.

Journal: Nucleosides, nucleotides & nucleic acids 20040101

Title: Synthesis of the antisense oligonucleotides carrying the modified 2-5A molecules at their 5'-termini and their properties.

Journal: Nucleic acids research. Supplement (2001) 20020101

Title: Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Journal: Clinical microbiology reviews 20010401

Title: Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents.

Journal: Journal of medicinal chemistry 19931001

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SDS
Tags:56973-12-7 Molecular Formula|56973-12-7 MDL|56973-12-7 SMILES|56973-12-7 8-methyladenosine