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57-66-9,MFCD00038402
Catalog No.:AA003TVV

57-66-9 | 4-(dipropylsulfamoyl)benzoic acid

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1g
98%
in stock  
$8.00   $5.00
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5g
98%(HPLC)
in stock  
$35.00   $25.00
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10g
≥98%
in stock  
$69.00   $48.00
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25g
98%
in stock  
$79.00   $55.00
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100g
98%
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500g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003TVV
Chemical Name:
4-(dipropylsulfamoyl)benzoic acid
CAS Number:
57-66-9
Molecular Formula:
C13H19NO4S
Molecular Weight:
285.3593
MDL Number:
MFCD00038402
SMILES:
CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC
UN Number:
3249
Properties
Properties
 
Form:
Solid  
MP:
194-196°C  
Refractive Index:
1.6800 (estimate)  
Storage:
Room Temperature;Light sensitive;  

Computed Properties
 
Complexity:
374  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
3.2  

Literature

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Title: Nitro-fatty acid inhibition of triple-negative breast cancer cell viability, migration, invasion, and tumor growth.

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Title: Gender-specific expression of ATP-binding cassette (Abc) transporters and cytoprotective genes in mouse choroid plexus.

Journal: Toxicology 20170701

Title: Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20170401

Title: Inhibition of SLC drug transporter activities by environmental bisphenols.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401

Title: Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate.

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Title: Inhibiting the Inflammasome: A Chemical Perspective.

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Title: Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.

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Title: The pharmacokinetics of oxypurinol in people with gout.

Journal: British journal of clinical pharmacology 20120901

Title: Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.

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Title: Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation.

Journal: Journal of molecular and cellular cardiology 20120701

Title: Dizziness and rash in an HIV positive man.

Journal: BMJ (Clinical research ed.) 20120628

Title: TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity.

Journal: American journal of physiology. Cell physiology 20120615

Title: Transepithelial transport of 4-chloro-2-methylphenoxyacetic acid (MCPA) across human intestinal Caco-2 cell monolayers.

Journal: Basic & clinical pharmacology & toxicology 20120601

Title: In vivo kinetics of indoxyl sulfate in humans and its renal interaction with angiotensin-converting enzyme inhibitor quinapril in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20120601

Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal: Journal of medicinal chemistry 20120524

Title: A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.

Journal: American journal of physiology. Renal physiology 20120515

Title: In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna.

Journal: Journal of clinical pharmacology 20120401

Title: Differences in the pharmacokinetics of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of resatorvid, in rats and dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401

Title: Pannexin1 drives multicellular aggregate compaction via a signaling cascade that remodels the actin cytoskeleton.

Journal: The Journal of biological chemistry 20120309

Title: The history and future of probenecid.

Journal: Cardiovascular toxicology 20120301

Title: Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells.

Journal: Toxicology letters 20120225

Title: Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3.

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Title: First evidence of epithelial transport in tardigrades: a comparative investigation of organic anion transport.

Journal: The Journal of experimental biology 20120201

Title: Organic anion transporters involved in the excretion of bestatin in the kidney.

Journal: Peptides 20120201

Title: [Transport of limonin in rat intestine in situ and Caco-2 cells in vitro].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120201

Title: Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid.

Journal: The Medical journal of Malaysia 20120201

Title: Protective compounds in animal models of trigeminal activation and neurodegeneration.

Journal: Ideggyogyaszati szemle 20120130

Title: Theaflavin, a black tea polyphenol, protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease.

Journal: Brain research 20120118

Title: Ethyl-eicosapentaenoate (E-EPA) attenuates motor impairments and inflammation in the MPTP-probenecid mouse model of Parkinson's disease.

Journal: Behavioural brain research 20120115

Title: Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels.

Journal: Glia 20120101

Title: Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells.

Journal: Lipids in health and disease 20120101

Title: African American patients with gout: efficacy and safety of febuxostat vs allopurinol.

Journal: BMC musculoskeletal disorders 20120101

Title: Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy.

Journal: Malaria journal 20120101

Title: The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age.

Journal: BMC geriatrics 20120101

Title: Low nasal carriage of drug-resistant bacteria among medical students in Vienna.

Journal: GMS Krankenhaushygiene interdisziplinar 20120101

Title: Testing for aerobic heterotrophic bacteria allows no prediction of contamination with potentially pathogenic bacteria in the output water of dental chair units.

Journal: GMS Krankenhaushygiene interdisziplinar 20120101

Title: Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium.

Journal: PloS one 20120101

Title: The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters.

Journal: The Journal of biological chemistry 20111230

Title: Risk factors of cellulitis treatment failure with once-daily intravenous cefazolin plus oral probenecid.

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Title: How clinical and research failures lead to suboptimal prescribing: the example of chronic gout.

Journal: BMJ (Clinical research ed.) 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

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Title: Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease.

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Title: Micellar electrokinetic chromatographic analysis for in vitro accumulation of anthracyclines enhanced by inhibitors of cell membrane transporter-proteins in cancer cells.

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Journal: Colloids and surfaces. B, Biointerfaces 20111001

Title: Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease.

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Title: Catastrophic axial gout causing paraplegia in a patient with glycogen storage disease.

Journal: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20111001

Title: Functional test of multidrug transporter activity in hippocampal-neocortical brain slices from epileptic patients.

Journal: Journal of neuroscience methods 20110915

Title: Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901

Title: Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid.

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Title: New bitter blocker discovered, study finds.

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Title: Organic anion and cation transporters are possibly involved in renal excretion of entecavir in rats.

Journal: Life sciences 20110704

Title: Interactions of human organic anion transporter 1 (hOAT1) with substances associated with forensic toxicology.

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Title: G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast.

Journal: Neuropharmacology 20110601

Title: Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout.

Journal: The Journal of rheumatology 20110501

Title: Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice.

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Title: Developing potent human uric acid transporter 1 (hURAT1) inhibitors.

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Title: Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegeneration.

Journal: The European journal of neuroscience 20110401

Title: Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.

Journal: The Journal of biological chemistry 20110304

Title: Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats.

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Title: Prevalence of contraindications and prescription of pharmacologic therapies for gout.

Journal: The American journal of medicine 20110201

Title: Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.

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Title: Protective effect of L-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: implications of modulating kynurenate as a protective strategy.

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Title: Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

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Title: Anti-hypertensive effects of probenecid via inhibition of the α-adrenergic receptor.

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Title: Decontamination of room air and adjoining wall surfaces by nebulizing hydrogen peroxide.

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Title: Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice.

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Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization.

Journal: American journal of physiology. Cell physiology 20101201

Title: Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow.

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Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

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Title: Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome.

Journal: International journal of clinical pharmacology and therapeutics 20101101

Title: Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20101001

Title: Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1).

Journal: The Journal of pharmacology and experimental therapeutics 20100901

Title: Uric acid increases fibronectin synthesis through upregulation of lysyl oxidase expression in rat renal tubular epithelial cells.

Journal: American journal of physiology. Renal physiology 20100801

Title: Protective effect of systemic L-kynurenine and probenecid administration on behavioural and morphological alterations induced by toxic soluble amyloid beta (25-35) in rat hippocampus.

Journal: Behavioural brain research 20100711

Title: cAMP efflux from human trophoblast cell lines: a role for multidrug resistance protein (MRP)1 transporter.

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Title: Modulated function of tissue efflux transporters under hyperbilirubinemia in rats.

Journal: European journal of pharmacology 20100625

Title: Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors.

Journal: Journal of biomolecular screening 20100601

Title: Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.

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Title: Tenofovir/probenecid combination in HIV/HBV-coinfected patients: how to escape Fanconi syndrome recurrence?

Journal: AIDS (London, England) 20100424

Title: Biliary efflux transporters involved in the clearance of rosuvastatin in sandwich culture of primary rat hepatocytes.

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Title: Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in rats.

Journal: The Journal of nutrition 20100301

Title: Comparative renal excretion of VX-702, a novel p38 MAPK inhibitor, and methotrexate in the perfused rat kidney model.

Journal: Drug development and industrial pharmacy 20100301

Title: Pharmacokinetic properties and bioequivalence of two compound formulations of 1500 mg ampicillin (1167 mg)/probenecid (333 mg): a randomized-sequence, single-dose, open-label, two-period crossover study in healthy Chinese male volunteers.

Journal: Clinical therapeutics 20100301

Title: Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor.

Journal: Brain research bulletin 20100215

Title: Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved.

Journal: Rheumatology international 20100201

Title: Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells.

Journal: American journal of physiology. Cell physiology 20100201

Title: Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid.

Journal: British journal of clinical pharmacology 20100201

Title: Masking and manipulation.

Journal: Handbook of experimental pharmacology 20100101

Title: On call. I've had gout for many years. I used to take Zyloprim without any problems, but I just had a severe allergic reaction, so my doctor switched me to Benemid. I'm doing okay, but the drug sometimes upsets my stomach. Do you have any suggestions?

Journal: Harvard men's health watch 20100101

Title: Interactions of human organic anion transporters with aristolochic acids.

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Title: [The clinical picture of gout is changing].

Journal: Duodecim; laaketieteellinen aikakauskirja 20100101

Title: Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Prognostic significance of p53-expression in colorectal carcinoma as measured by a luminometric immunoassay.

Journal: German medical science : GMS e-journal 20100101

Title: Pannexin 1 contributes to ATP release in airway epithelia.

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Title: Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

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Title: Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.

Journal: Journal of medicinal chemistry 20090910

Title: Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease.

Journal: Experimental neurology 20090901

Title: Neuroprotective effects of probenecid in a transgenic animal model of Huntington's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090901

Title: l-kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus.

Journal: Neuropharmacology 20090901

Title: Influence of efflux transporters on liver, bile and brain disposition of amitriptyline in mice.

Journal: International journal of pharmaceutics 20090813

Title: Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease.

Journal: Physiology & behavior 20090804

Title: Opportunities for improving medication use and monitoring in gout.

Journal: Annals of the rheumatic diseases 20090801

Title: Thrombocytopenia from combination treatment with oseltamivir and probenecid: case report, MedWatch data summary, and review of the literature.

Journal: Pharmacotherapy 20090801

Title: Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder.

Journal: Rejuvenation research 20090801

Title: Probenecid, an inhibitor of transmembrane organic anion transporters, alters tissue distribution of DNA adducts in 1-hydroxymethylpyrene-treated rats.

Journal: Toxicology 20090728

Title: The effect of probenecid and MK-571 on the feto-maternal transfer of saquinavir in dually perfused human term placenta.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090712

Title: Evaluation of substrate and inhibitor properties of a novel MDR modulator H17 towards transmembrane efflux pumps.

Journal: European journal of medicinal chemistry 20090701

Title: Organic anion transporter OAT1 is involved in renal handling of citrulline.

Journal: American journal of physiology. Renal physiology 20090701

Title: Uptake of metronidazole by human gingival fibroblasts.

Journal: Journal of periodontology 20090601

Title: Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

Journal: Tissue & cell 20090401

Title: Esterified trityl radicals as intracellular oxygen probes.

Journal: Free radical biology & medicine 20090401

Title: Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells.

Journal: American journal of physiology. Cell physiology 20090401

Title: Should syphilis be treated differently in HIV-positive and HIV-negative individuals? Treatment outcomes at a university hospital, Brighton, UK.

Journal: International journal of STD & AIDS 20090401

Title: Thermodynamics of cosolvent action: phenacetin, salicylic acid and probenecid.

Journal: Journal of pharmaceutical sciences 20090301

Title: The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090301

Title: A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis.

Journal: The Journal of biological chemistry 20090213

Title: Pharmacological characterization of pannexin-1 currents expressed in mammalian cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Functionality of drug efflux pumps in antimonial resistant Leishmania donovani field isolates.

Journal: Indian journal of biochemistry & biophysics 20090201

Title: Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice.

Journal: Neuroscience letters 20090130

Title: Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol.

Journal: Annals of the rheumatic diseases 20090101

Title: Low dosage cidofovir without probenecid as treatment for BK virus hamorrhagic cystitis after hemopoietic stem cell transplant.

Journal: The Pediatric infectious disease journal 20090101

Title: Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration.

Journal: BMC neuroscience 20090101

Title: Effect of probenecid on kinetics of enrofloxacin in lactating goats after subcutaneous administration.

Journal: Indian journal of experimental biology 20090101

Title: Adherence with urate-lowering therapies for the treatment of gout.

Journal: Arthritis research & therapy 20090101

Title: Detection of HER-2/neu, c-myc amplification and p53 inactivation by FISH in Egyptian patients with breast cancer.

Journal: German medical science : GMS e-journal 20090101

Title: Paclitaxel-resistance conferred by altered expression of efflux and influx transporters for paclitaxel in the human hepatoma cell line, HepG2.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Membrane Based Measurement Technology for in situ Monitoring of Gases in Soil.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus.

Journal: Neurobiology of disease 20081101

Title: Modelling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid.

Journal: Journal of neurochemistry 20081101

Title: Influence of cyclic guanosine 3',5' monophosphate modulators on muscle contraction of rat aortas.

Journal: Saudi medical journal 20081101

Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal: Journal of medicinal chemistry 20081009

Title: Evaluation of the selected barrier properties of retinal pigment epithelial cell line ARPE-19 for an in-vitro blood-brain barrier model.

Journal: Human & experimental toxicology 20081001

Title: Probenecid, a gout remedy, inhibits pannexin 1 channels.

Journal: American journal of physiology. Cell physiology 20080901

Title: Role of organic anion transporters in the pharmacokinetics of zonampanel, an alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist, in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

Journal: Journal of clinical pharmacology 20080801

Title: Population pharmacokinetics of oseltamivir when coadministered with probenecid.

Journal: Journal of clinical pharmacology 20080801

Title: Capillary electrophoresis of diuretics and probenecid in methanol.

Journal: Journal of chromatography. A 20080711

Title: Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis.

Journal: Pharmacotherapy 20080701

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Stroke in pregnancy associated with syphilis.

Journal: The journal of obstetrics and gynaecology research 20080601

Title: Uric acid lowering therapy: prescribing patterns in a large cohort of older adults.

Journal: Annals of the rheumatic diseases 20080501

Title: Neuroprotection achieved in the ischaemic rat cortex with L-kynurenine sulphate.

Journal: Life sciences 20080423

Title: Role of multi-drug resistance-associated protein-1 transporter in statin-induced myopathy.

Journal: Life sciences 20080409

Title: Pharmacokinetics, tissue distribution and excretion of a new photodynamic drug deuxemether.

Journal: Journal of photochemistry and photobiology. B, Biology 20080328

Title: Fluorescence-enhanced europium-diethylenetriaminepentaacetic (DTPA)-monoamide complexes for the assessment of renal function.

Journal: Journal of medicinal chemistry 20080227

Title: Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?

Journal: American journal of obstetrics and gynecology 20080101

Title: Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects.

Journal: Clinical pharmacokinetics 20080101

Title: Mrp2-related efflux of scutellarin in the intestinal absorption in rats.

Journal: Die Pharmazie 20080101

Title: Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress.

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20071201

Title: Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats.

Journal: Drug metabolism and pharmacokinetics 20071201

Title: Gout: joint pain and more.

Journal: Harvard men's health watch 20071201

Title: Pharmacokinetics of 3-[125I]iodo-alpha-methyl-L-tyrosine, a tumor imaging agent, after probenecid loading in mice implanted with colon cancer DLD-1 cells.

Journal: Nuclear medicine and biology 20071101

Title: Management of cellulitis in a pediatric emergency department.

Journal: Pediatric emergency care 20071101

Title: Effect of probenecid on the biliary excretion of belotecan.

Journal: Archives of pharmacal research 20071101

Title: Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of parkinsonism with severe neurodegeneration.

Journal: Neuroscience 20071012

Title: Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.

Journal: Chemical research in toxicology 20071001

Title: Transient receptor potential V2 expressed in sensory neurons is activated by probenecid.

Journal: Neuroscience letters 20070925

Title: Possible involvement of organic anion and cation transporters in renal excretion of xanthine derivatives, 3-methylxanthine and enprofylline.

Journal: Life sciences 20070922

Title: Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients.

Journal: Clinical rheumatology 20070901

Title: Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection.

Journal: Pharmaceutical research 20070801

Title: Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Probenecid-induced membranous nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801

Title: Molecular epidemiology of malaria in Cameroon. XXVI. Twelve-year in vitro and molecular surveillance of pyrimethamine resistance and experimental studies to modulate pyrimethamine resistance.

Journal: The American journal of tropical medicine and hygiene 20070801

Title: Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid.

Journal: International journal of clinical pharmacology and therapeutics 20070801

Title: PET-evaluated transport of [11C]hydroxyurea across the rat blood-brain barrier--lack of influence of cyclosporin and probenecid.

Journal: Drug metabolism letters 20070801

Title: Molecular mechanism of alpha-tocopheryl-phosphate transport across the cell membrane.

Journal: Biochemical and biophysical research communications 20070727

Title: Isolation and characterization of polyspecific mouse organic solute carrier protein 1 (mOscp1).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Identification of molecular compounds critical to Alzheimer's-like plaque formation.

Journal: Journal of neuroscience research 20070701

Title: Mechanistic study on the intestinal absorption and disposition of baicalein.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701

Title: Characterisation of exogenous folate transport in Plasmodium falciparum.

Journal: Molecular and biochemical parasitology 20070701

Title: Active renal secretion of NXY-059, a novel neuroprotectant, is mediated via an organic acid transporter.

Journal: Journal of clinical pharmacology 20070701

Title: Electrokinetic migration of acidic drugs across a supported liquid membrane.

Journal: Journal of chromatography. A 20070608

Title: Morin (3,5,7,2',4'-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601

Title: Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070601

Title: Prevention of electrical stimulation-induced increase of c-fos immunoreaction in the caudal trigeminal nucleus by kynurenine combined with probenecid.

Journal: Neuroscience letters 20070517

Title: The pancreatohepatorenal cAMP-adenosine mechanism.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.

Journal: Current drug metabolism 20070501

Title: Quantitation of Armillarisin A in human plasma by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20070411

Title: Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

Journal: European journal of pharmacology 20070410

Title: Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).

Journal: Pharmaceutical research 20070401

Title: One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.

Journal: Transfusion 20070401

Title: Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells.

Journal: The Journal of pharmacy and pharmacology 20070401

Title: Progesterone inhibits folic acid transport in human trophoblasts.

Journal: The Journal of membrane biology 20070401

Title: DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833.

Journal: Toxicology letters 20070227

Title: Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.

Journal: Drug metabolism and pharmacokinetics 20070225

Title: Schisandrin B: a dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1.

Journal: Cancer letters 20070208

Title: Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201

Title: Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070101

Title: Kynurenine in combination with probenecid mitigates the stimulation-induced increase of c-fos immunoreactivity of the rat caudal trigeminal nucleus in an experimental migraine model.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070101

Title: In silico prediction of pregnane X receptor activators by machine learning approaches.

Journal: Molecular pharmacology 20070101

Title: [A case of papillitis revealing primary syphilis].

Journal: Medecine et maladies infectieuses 20070101

Title: Mitoxantrone permeability in MDCKII cells is influenced by active influx transport.

Journal: Molecular pharmaceutics 20070101

Title: Flow cytometric monitoring of multidrug drug resistance protein 1 (MRP1/ABCC1) -mediated transport of 2',7'-bis-(3-carboxypropyl)-5-(and-6)- carboxyfluorescein (BCPCF) into human erythrocyte membrane inside-out vesicles.

Journal: Molecular membrane biology 20070101

Title: [Diagnosis of interstitial nephropathy caused by BK virus in renal transplantation. Therapeutic management with cidofovir plus probenecid].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101

Title: Verapamil, but not probenecid, co-administration can convert desloratadine to a sedating antihistamine in mice.

Journal: Drug metabolism letters 20070101

Title: High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid.

Journal: Circulation 20061205

Title: Schistosoma mansoni: biochemical characterization of lactate transporters or similar proteins.

Journal: Experimental parasitology 20061101

Title: Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.

Journal: The Journal of pharmacy and pharmacology 20061101

Title: Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061001

Title: Potential gamma-hydroxybutyric acid (GHB) drug interactions through blood-brain barrier transport inhibition: a pharmacokinetic simulation-based evaluation.

Journal: Journal of pharmacokinetics and pharmacodynamics 20061001

Title: Function of multidrug resistance-associated protein 2 in acute hepatic failure rats.

Journal: European journal of pharmacology 20060928

Title: Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.

Journal: Epilepsy research 20060901

Title: Membrane transporter proteins: a challenge for CNS drug development.

Journal: Dialogues in clinical neuroscience 20060901

Title: Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20).

Journal: American journal of physiology. Renal physiology 20060801

Title: The efflux of flavonoids morin, isorhamnetin-3-O-rutinoside and diosmetin-7-O-beta-D-xylopyranosyl-(1-6) -beta-D-glucopyranoside in the human intestinal cell line caco-2.

Journal: Pharmaceutical research 20060801

Title: A blistering disease: bullous erysipelas.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060801

Title: Efficacy of probenecid for a patient with juvenile dermatomyositis complicated with calcinosis.

Journal: The Journal of rheumatology 20060801

Title: Apparent active transport of MDMA is not mediated by P-glycoprotein: a comparison with MDCK and Caco-2 monolayers.

Journal: Biopharmaceutics & drug disposition 20060701

Title: Tubular transporters and clearance of adefovir.

Journal: European journal of pharmacology 20060701

Title: Human vascular smooth muscle cells express a urate transporter.

Journal: Journal of the American Society of Nephrology : JASN 20060701

Title: Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060501

Title: A phase I clinical pharmacologic study of pralatrexate in combination with probenecid in adults with advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20060501

Title: Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501

Title: Transfer of probenecid and cephalexin into breast milk.

Journal: The Annals of pharmacotherapy 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Carrier-mediated processes at several rat brain interfaces determine the neuropharmacokinetics of morphine and morphine-6-beta-D-glucuronide.

Journal: Life sciences 20060411

Title: Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401

Title: Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Probenecid with oseltamivir for human influenza A (H5N1) virus infection?

Journal: The New England journal of medicine 20060223

Title: In vivo and in vitro modulation of MDR molecules in murine thymocytes.

Journal: International immunopharmacology 20060201

Title: Intermediate-dose cidofovir without probenecid in the treatment of BK virus allograft nephropathy.

Journal: Pediatric transplantation 20060201

Title: [Molecular mechanism in biological transport in the kidney: Urate transporter URAT1].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060201

Title: A concise history of gout and hyperuricemia and their treatment.

Journal: Arthritis research & therapy 20060101

Title: Elevated reactive oxygen species but not glutathione regulate mercury resistance to AML-2/DX100 cells.

Journal: Immunopharmacology and immunotoxicology 20060101

Title: Febuxostat--treatment for hyperuricemia and gout?

Journal: The New England journal of medicine 20051208

Title: Transepithelial transport of fluorescent p-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets.

Journal: The Journal of experimental biology 20051201

Title: Wartime tactic doubles power of scarce bird-flu drug.

Journal: Nature 20051103

Title: Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules.

Journal: The Journal of pharmacology and experimental therapeutics 20051101

Title: Handling of the homocysteine S-conjugate of methylmercury by renal epithelial cells: role of organic anion transporter 1 and amino acid transporters.

Journal: The Journal of pharmacology and experimental therapeutics 20051101

Title: Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: An update on the treatment options for gout and calcium pyrophosphate deposition.

Journal: Expert opinion on pharmacotherapy 20051101

Title: Transepithelial urate transport by avian renal proximal tubule epithelium in primary culture.

Journal: The Journal of experimental biology 20051101

Title: [Tubular transporters OAT1 and MRP2 and clearance of adefovir].

Journal: Nephrologie & therapeutique 20051101

Title: A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051001

Title: Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1.

Journal: Kidney international 20051001

Title: Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.

Journal: Epilepsia 20051001

Title: MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.

Journal: International journal of cancer 20050920

Title: Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Effects of active transport of 5-hydroxyindoleacetic acid on measures of serotonin metabolism in the brain.

Journal: Neuroscience and behavioral physiology 20050901

Title: Modulation of MRP1 protein transport by plant, and synthetically modified flavonoids.

Journal: Life sciences 20050826

Title: Phenolsulfonphthalein transport by potential-sensitive urate transport system.

Journal: European journal of pharmacology 20050822

Title: Functional involvement of rat organic anion transporter 2 (Slc22a7) in the hepatic uptake of the nonsteroidal anti-inflammatory drug ketoprofen.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: Mrp2/Abcc2 transport activity is stimulated by protein kinase Calpha in a baculo virus co-expression system.

Journal: Life sciences 20050617

Title: Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects.

Journal: European journal of clinical pharmacology 20050601

Title: Specificity of the fluorescein transport process in Malpighian tubules of the cricket Acheta domesticus.

Journal: The Journal of experimental biology 20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Functional expression of pig renal organic anion transporter 3 (pOAT3).

Journal: Biochimie 20050501

Title: The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

Journal: Molecular cancer therapeutics 20050501

Title: Systemically administered glucosamine-kynurenic acid, but not pure kynurenic acid, is effective in decreasing the evoked activity in area CA1 of the rat hippocampus.

Journal: European journal of pharmacology 20050418

Title: Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects.

Journal: American journal of physiology. Renal physiology 20050401

Title: UDP-glucuronosyltransferases and clinical drug-drug interactions.

Journal: Pharmacology & therapeutics 20050401

Title: Expression and activity of multidrug resistance protein 1 in a murine thymoma cell line.

Journal: Immunology 20050401

Title: Altered brain penetration of diclofenac and mefenamic acid, but not acetaminophen, in Shiga-like toxin II-treated mice.

Journal: Journal of pharmacological sciences 20050401

Title: Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein.

Journal: Toxicon : official journal of the International Society on Toxinology 20050301

Title: Synthesis and biological testing of aminoxyls designed for long-term retention by living cells.

Journal: Organic & biomolecular chemistry 20050221

Title: Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).

Journal: Molecular pharmacology 20050201

Title: Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis.

Journal: Journal of medical virology 20050201

Title: Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.

Journal: Biochemical pharmacology 20050201

Title: Characterization of secretory intestinal transport of phenolsulfonphthalein.

Journal: Drug metabolism and pharmacokinetics 20050201

Title: Mercury induces multidrug resistance-associated protein gene through p38 mitogen-activated protein kinase.

Journal: Toxicology letters 20050115

Title: Pharmacology of drugs for hyperuricemia. Mechanisms, kinetics and interactions.

Journal: Contributions to nephrology 20050101

Title: Potential utility of natural polyphenols for reversing fat-induced insulin resistance.

Journal: Medical hypotheses 20050101

Title: Influence of probenecid on the delivery of morphine-6-glucuronide to the brain.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101

Title: Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

Journal: Clinical pharmacology and therapeutics 20050101

Title: The outcome of oropharyngeal gonorrhoea treatment with different regimens.

Journal: International journal of STD & AIDS 20050101

Title: Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts.

Journal: Anticancer research 20050101

Title: Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter.

Journal: American journal of nephrology 20050101

Title: Multidrug resistance-associated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050101

Title: Beta-trace protein (prostaglandin D synthase)--a stable and reliable protein in perilymph.

Journal: German medical science : GMS e-journal 20050101

Title: Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.

Journal: British journal of pharmacology 20041201

Title: Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans.

Journal: Anesthesiology 20041201

Title: Comparative effects of pyrimethamine-sulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria.

Journal: Annals of tropical medicine and parasitology 20041201

Title: Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease.

Journal: Experimental neurology 20041101

Title: Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.

Journal: Journal of the American Society of Nephrology : JASN 20041101

Title: Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study.

Journal: Neuropharmacology 20041101

Title: Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier.

Journal: Endocrinology 20040901

Title: Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901

Title: Monocarboxylate transport inhibition alters retinal function and cellular amino acid levels.

Journal: The European journal of neuroscience 20040901

Title: An integrated model for the analysis of pharmacokinetic data from microdialysis experiments.

Journal: Pharmaceutical research 20040901

Title: Syphilis in the HIV-infected patient: an update on epidemiology, diagnosis, and management.

Journal: Current HIV/AIDS reports 20040901

Title: Endogenous kynurenic acid disrupts prepulse inhibition.

Journal: Biological psychiatry 20040815

Title: Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

Journal: American journal of physiology. Renal physiology 20040801

Title: ATP binding cassette multidrug transporters limit the anti-HIV activity of zidovudine and indinavir in infected human macrophages.

Journal: Antiviral therapy 20040801

Title: [Synthesis of polymeric drug nanomicrospheres containing probenecid].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20040801

Title: The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter.

Journal: The Journal of physiology 20040615

Title: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20040601

Title: Multidrug resistance protein (MRP) 4- and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl)adenine by microglia.

Journal: The Journal of pharmacology and experimental therapeutics 20040601

Title: Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines.

Journal: Leukemia research 20040601

Title: Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

Journal: Pharmaceutical research 20040601

Title: Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Journal: Cancer chemotherapy and pharmacology 20040501

Title: Localization of heparin and low-molecular-weight heparin in the rat kidney.

Journal: Thrombosis and haemostasis 20040501

Title: Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.

Journal: Tropical medicine & international health : TM & IH 20040501

Title: Hepatobiliary excretion of berberine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: [Role of active transport of 5-hydroxyindoleacetic acid in serotonin metabolism in the brain].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20040401

Title: Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa.

Journal: Biochemical pharmacology 20040315

Title: Once-daily cefazolin and probenecid for skin and soft tissue infections.

Journal: The Annals of pharmacotherapy 20040301

Title: Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potential.

Journal: British journal of pharmacology 20040301

Title: Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.

Journal: Trends in parasitology 20040301

Title: Production and role of extracellular guanosine cyclic 3', 5' monophosphate in sodium uptake in human proximal tubule cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20040201

Title: Function and localization of urate transporter 1 in mouse kidney.

Journal: Journal of the American Society of Nephrology : JASN 20040201

Title: [Therapy of syphilis].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040201

Title: Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

Journal: Journal of pharmacological sciences 20040201

Title: Inhibition of multidrug transporters by verapamil or probenecid does not alter blood-brain barrier penetration of levetiracetam in rats.

Journal: Epilepsy research 20040201

Title: Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.

Journal: Journal of the American Society of Nephrology : JASN 20040101

Title: Transport of 99mTc-MAG3 via rat renal organic anion transporter 1.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040101

Title: Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport.

Journal: Epilepsy research 20040101

Title: Cryptosporidium parvum: effect of multi-drug reversing agents on the expression and function of ATP-binding cassette transporters.

Journal: Experimental parasitology 20040101

Title: Hyperuricaemia and preeclampsia: is there a pathogenic link?

Journal: Medical hypotheses 20040101

Title: Bodipy-FL-verapamil: a fluorescent probe for the study of multidrug resistance proteins.

Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology 20040101

Title: Two male siblings with hereditary renal hypouricemia and exercise-induced ARF.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20031201

Title: Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport.

Journal: Toxicology and applied pharmacology 20031115

Title: Effect of probenecid and quinidine on the transport of alovudine (3'-fluorothymidine) to the rat brain studied by microdialysis.

Journal: Pharmacology & toxicology 20031101

Title: Multidrug-resistant tumor cells remain sensitive to a recombinant interleukin-4-Pseudomonas exotoxin, except when overexpressing the multidrug resistance protein MRP1.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031015

Title: Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.

Journal: Biochemical and biophysical research communications 20031010

Title: Functional expression of the multidrug resistance protein 1 in microglia.

Journal: The Journal of pharmacology and experimental therapeutics 20031001

Title: Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.

Journal: Neuropharmacology 20031001

Title: Sources for superoxide release: lessons from blockade of electron transport, NADPH oxidase, and anion channels in diaphragm.

Journal: Antioxidants & redox signaling 20031001

Title: Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter.

Journal: FEBS letters 20030911

Title: Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier.

Journal: Journal of neurochemistry 20030901

Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

Journal: Hepatology (Baltimore, Md.) 20030801

Title: UV or X-irradiation increases the cytoplasmic accumulation of rhodamine 123 in various cancer cell lines.

Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20030801

Title: Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

Journal: The Journal of biological chemistry 20030627

Title: Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells.

Journal: Pharmaceutical research 20030601

Title: Probenecid-induced changes in the clearance of pranoprofen enantiomers.

Journal: Chirality 20030505

Title: Effect of chronic probenecid therapy on cefazolin serum concentrations.

Journal: The Annals of pharmacotherapy 20030501

Title: Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.

Journal: American journal of physiology. Renal physiology 20030401

Title: Control of hepatocyte DNA synthesis by intracellular pH and its role in the action of tumor promoters.

Journal: Journal of cellular physiology 20030401

Title: An artificial amino acid, 4-iodo-L-meta-tyrosine: biodistribution and excretion via kidney.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030401

Title: Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401

Title: ATP released from astrocytes during swelling activates chloride channels.

Journal: Journal of neurophysiology 20030401

Title: Morphine blood-brain barrier transport is influenced by probenecid co-administration.

Journal: Pharmaceutical research 20030401

Title: Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.

Journal: European journal of pharmacology 20030328

Title: Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells.

Journal: Molecular pharmacology 20030301

Title: Sulfate conjugating and transport functions of MDCK distal tubular cells.

Journal: Kidney international 20030301

Title: Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Transport of 5-formyltetrahydrofolate into primary cultured rat astrocytes.

Journal: Archives of biochemistry and biophysics 20030201

Title: Mechanisms by which 2',3'-dideoxyinosine (ddI) crosses the guinea-pig CNS barriers; relevance to HIV therapy.

Journal: Journal of neurochemistry 20030201

Title: Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug.

Journal: British journal of clinical pharmacology 20030201

Title: Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites.

Journal: Chemico-biological interactions 20030106

Title: Prolactin regulation of the pendrin-iodide transporter in the mammary gland.

Journal: American journal of physiology. Endocrinology and metabolism 20030101

Title: Urate transport via human PAH transporter hOAT1 and its gene structure.

Journal: Kidney international 20030101

Title: Pharmacokinetics and renal effects of cidofovir with a reduced dose of probenecid in HIV-infected patients with cytomegalovirus retinitis.

Journal: Journal of clinical pharmacology 20030101

Title: No-wash dyes for calcium flux measurement.

Journal: BioTechniques 20030101

Title: Endometritis does not predict reproductive morbidity after pelvic inflammatory disease.

Journal: American journal of obstetrics and gynecology 20030101

Title: Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats.

Journal: Pharmaceutical research 20030101

Title: [Drug therapy for idiopathic hyperuricemia--introduction, dose, and side effects].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030101

Title: [Molecular mechanism for urinary excretion of hypoxanthine and xanthine].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030101

Title: Effect of the dimeric bile acid analogue S 0960, a specific inhibitor of the apical sodium-dependent bile salt transporter in the ileum, on the renal handling of taurocholate.

Journal: Arzneimittel-Forschung 20030101

Title: Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells.

Journal: Cancer research 20021215

Title: Single-cell image analysis to assess ABC-transporter-mediated efflux in highly purified hematopoietic progenitors.

Journal: Cytometry 20021201

Title: Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20021201

Title: p-Aminohippurate transport at the apical membrane in the OK kidney epithelial cell line.

Journal: Pharmaceutical research 20021201

Title: Lyme disease.

Journal: Clinical evidence 20021201

Title: Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease.

Journal: Brain research 20021122

Title: Tumour cell uptake of the metastasis inhibitor ruthenium complex NAMI-A and its in vitro effects on KB cells.

Journal: Cancer chemotherapy and pharmacology 20021101

Title: Involvement of multidrug resistance proteins (MDR) in the modulation of glucocorticoid response.

Journal: The Journal of steroid biochemistry and molecular biology 20021101

Title: Functional analysis of ABCA8, a new drug transporter.

Journal: Biochemical and biophysical research communications 20021018

Title: Disposition of acamprosate in the rat: influence of probenecid.

Journal: Biopharmaceutics & drug disposition 20021001

Title: The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).

Journal: AIDS (London, England) 20020906

Title: Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.

Journal: Journal of pineal research 20020901

Title: Chronic arsenic-exposed human prostate epithelial cells exhibit stable arsenic tolerance: mechanistic implications of altered cellular glutathione and glutathione S-transferase.

Journal: Toxicology and applied pharmacology 20020901

Title: Reduced gastrointestinal toxicity following inhibition of the biliary excretion of irinotecan and its metabolites by probenecid in rats.

Journal: Pharmaceutical research 20020901

Title: The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats.

Journal: Neuroscience letters 20020830

Title: Characterization of methotrexate transport and its drug interactions with human organic anion transporters.

Journal: The Journal of pharmacology and experimental therapeutics 20020801

Title: Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection.

Journal: The Journal of infectious diseases 20020801

Title: Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

Journal: The Journal of biological chemistry 20020726

Title: CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701

Title: Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity.

Journal: Journal of the American Society of Nephrology : JASN 20020701

Title: Outpatient pelvic inflammatory disease treatment as effective as inpatient care, study finds.

Journal: Report on medical guidelines & outcomes research 20020614

Title: Role of human organic anion transporter 4 in the transport of ochratoxin A.

Journal: Biochimica et biophysica acta 20020612

Title: Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020601

Title: Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics 20020601

Title: Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.

Journal: Cancer research 20020601

Title: Methylmercury accumulation and fluxes across the intestine of channel catfish, Ictalurus punctatus.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

Title: Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

Journal: The Journal of biological chemistry 20020510

Title: Neotrofin is transported out of brain by a saturable mechanism: possible involvement of multidrug resistance and monocarboxylic acid transporters.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501

Title: Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.

Journal: Molecular pharmacology 20020501

Title: Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.

Journal: Kidney international 20020501

Title: 99mTc-N, N'-bis(aminoethyl)propanediamine hexaacetic acid (BPHA): a glomerular filtration agent similar to 99mTc-DTPA.

Journal: Nuclear medicine and biology 20020501

Title: The influence of P-glycoprotein on morphine transport in Caco-2 cells. Comparison with paclitaxel.

Journal: European journal of pharmacology 20020405

Title: Mapping of local renal blood flow with PET and H(2)(15)O.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020401

Title: Contributions of saturable active secretion, passive transcellular, and paracellular diffusion to the overall transport of furosemide across adenocarcinoma (Caco-2) cells.

Journal: Journal of pharmaceutical sciences 20020401

Title: Mechanism and regulation of vitamin B(6) uptake by renal tubular epithelia: studies with cultured OK cells.

Journal: American journal of physiology. Renal physiology 20020301

Title: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

Journal: Journal of the American Society of Nephrology : JASN 20020301

Title: Human organic anion transporters and human organic cation transporters mediate renal antiviral transport.

Journal: The Journal of pharmacology and experimental therapeutics 20020301

Title: Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1).

Journal: European journal of pharmacology 20020215

Title: Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.

Journal: Leukemia research 20020201

Title: [Hyperuricemia and gout--treatment].

Journal: Deutsche medizinische Wochenschrift (1946) 20020201

Title: The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors.

Journal: Journal of neurochemistry 20020201

Title: The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in goats given enrofloxacin alone and in combination with probenecid.

Journal: Veterinary journal (London, England : 1997) 20020101

Title: Cidofovir-induced end-stage renal failure.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020101

Title: The effects of probenecid on the disposition of risperidone and olanzapine in healthy volunteers.

Journal: Clinical pharmacology and therapeutics 20020101

Title: Transport of methotrexate into LNCaP human prostate cancer cells.

Journal: BioFactors (Oxford, England) 20020101

Title: The potential for an interaction between MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites.

Journal: Drug metabolism and pharmacokinetics 20020101

Title: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

Journal: The Journal of biological chemistry 20011207

Title: P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain.

Journal: Neuroreport 20011116

Title: Interleukin-1beta stimulates cyclic GMP efflux in brain astrocytes.

Journal: FEBS letters 20011102

Title: Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models.

Journal: Pharmaceutical research 20011101

Title: Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.

Journal: Bone marrow transplantation 20011101

Title: Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome.

Journal: The Journal of biological chemistry 20011005

Title: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

Journal: Cancer research 20011001

Title: Efflux of a suppressive neurotransmitter, GABA, across the blood-brain barrier.

Journal: Journal of neurochemistry 20011001

Title: Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats.

Journal: Intensive care medicine 20011001

Title: Sex-related differences in the renal disposition of the acidic metabolite of clentiazem in rat.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20011001

Title: Influence of multidrug resistance (MDR) proteins at the blood-brain barrier on the transport and brain distribution of enaminone anticonvulsants.

Journal: Journal of pharmaceutical sciences 20011001

Title: Characterization of ochratoxin A transport by human organic anion transporters.

Journal: Life sciences 20010921

Title: Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.

Journal: American journal of physiology. Renal physiology 20010901

Title: Induction of chemoresistance in HL-60 cells concomitantly causes a resistance to apoptosis and the synthesis of P-glycoprotein.

Journal: Leukemia 20010901

Title: Effect of probenecid on ventricular cerebrospinal fluid methotrexate pharmacokinetics after intralumbar administration in nonhuman primates.

Journal: Cancer chemotherapy and pharmacology 20010901

Title: Effect of acetazolamide on outward permeability of blood-retina barrier using differential vitreous flyorophotometry.

Journal: Current eye research 20010901

Title: Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain.

Journal: Neuroreport 20010808

Title: Nifedipine modulation of biliary GSH and GSSG/ conjugate efflux in normal and regenerating rat liver.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010701

Title: Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20010701

Title: Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice.

Journal: Biochemical and biophysical research communications 20010622

Title: Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.

Journal: European journal of pharmacology 20010511

Title: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.

Journal: Molecular pharmacology 20010501

Title: Probenecid-associated alterations in valproic acid pharmacokinetics in rats: can in vivo disposition of valproate glucuronide be predicted from in vitro formation data?

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010501

Title: Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid.

Journal: Biochemical and biophysical research communications 20010427

Title: Probenecid-associated alterations in valproate glucuronide hepatobiliary disposition: mechanistic assessment using mathematical modeling.

Journal: The Journal of pharmacology and experimental therapeutics 20010401

Title: Furosemide-probenecid interaction as a laboratory exercise for undergraduate education in clinical pharmacology.

Journal: Clinical pharmacology and therapeutics 20010401

Title: Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

Journal: AIDS (London, England) 20010309

Title: A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells.

Journal: Pharmaceutical research 20010201

Title: Interactions between cimetidine, nitrofurantoin, and probenecid active transport into rat milk.

Journal: The Journal of pharmacology and experimental therapeutics 20010101

Title: Effects of probenecid on renal function in surgical patients anesthetized with low-flow sevoflurane.

Journal: Anesthesiology 20010101

Title: Secretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue.

Journal: The Journal of pharmacy and pharmacology 20010101

Title: Identification of an organic anion transport system in the human colon carcinoma cell line HT29 clone 19A.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: Effect of probenecid on the kinetics of a single oral 400mg dose of moxifloxacin in healthy male volunteers.

Journal: Clinical pharmacokinetics 20010101

Title: Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.

Journal: Neuroscience 20010101

Title: The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides.

Journal: The Journal of biological chemistry 20000929

Title: Subjective sensation of heaviness in gout patients.

Journal: Hiroshima journal of medical sciences 20000601

Title: Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions.

Journal: Molecular pharmacology 20000401

Title: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

Journal: The Journal of biological chemistry 20000211

Title: Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity.

Journal: Kidney international 19991201

Title: Transport of ochratoxin A by renal multispecific organic anion transporter 1.

Journal: The Journal of pharmacology and experimental therapeutics 19990601

Title: Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

Journal: The Journal of biological chemistry 19990507

Title: Restoration of the uricosuric effect of probenecid after triglycylvasopressine administration in a gouty patient.

Journal: Clinical nephrology 19981001

Title: Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats.

Journal: Anesthesiology 19980601

Title: The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.

Journal: Archives of toxicology 19980501

Title: Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19980401

Title: Mixed effects of 2,6-dithiopurine against cyclophosphamide mediated bladder and lung toxicity in mice.

Journal: Toxicology 19980116

Title: Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells.

Journal: International journal of cancer 19970926

Title: Possible role of the multidrug resistance-associated protein (MRP) in chemoresistance of human melanoma cells.

Journal: International journal of cancer 19970328

Title: Probenecid reverses multidrug resistance in multidrug resistance-associated protein-overexpressing HL60/AR and H69/AR cells but not in P-glycoprotein-overexpressing HL60/Tax and P388/ADR cells.

Journal: Cancer chemotherapy and pharmacology 19970101

Title: Transport of the antiviral nucleoside analogs 3'-azido-3'-deoxythymidine and 2',3'-dideoxycytidine by a recombinant nucleoside transporter (rCNT) expressed in Xenopus laevis oocytes.

Journal: Molecular pharmacology 19960801

Title: Renal handling of urate in a patient with familial juvenile gouty nephropathy.

Journal: Internal medicine (Tokyo, Japan) 19960701

Title: Expression of a renal type I sodium/phosphate transporter (NaPi-1) induces a conductance in Xenopus oocytes permeable for organic and inorganic anions.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19960528

Title: Pharmacokinetics of bacampicillin in equids.

Journal: American journal of veterinary research 19951101

Title: Nephrotoxicity of 4-amino-3-S-glutathionylphenol and its modulation by metabolism or transport inhibitors.

Journal: Archives of toxicology 19940101

Title: Renal hypouricemia due to enhanced tubular secretion of urate associated with urolithiasis: successful treatment of urolithiasis by alkalization of urine K+, Na(+)-citrate.

Journal: Nephron 19930101

Title: In vivo nephrotoxic action of an isomeric mixture of S-(1-phenyl-2-hydroxyethyl)glutathione and S-(2-phenyl-2-hydroxyethyl)glutathione in Fischer-344 rats.

Journal: Toxicology 19910325

Title: Probenecid and zidovudine metabolism.

Journal: Lancet (London, England) 19890826

Title: Probenecid induced immune hemolytic anemia.

Journal: The Journal of rheumatology 19860201

Title: Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.

Journal: Biochemical pharmacology 19860115

Title: The mechanisms of target cell injury by nephrotoxins.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19860101

Title: Immune hemolytic anemia associated with probenecid.

Journal: American journal of clinical pathology 19850901

Title: Role of renal metabolism and excretion in 5-nitrofuran-induced uroepithelial cancer in the rat.

Journal: The Journal of clinical investigation 19850901

Title: Enhancement of cisplatin nephrotoxicity by probenecid.

Journal: Cancer treatment reports 19840201

Title: One gram of cefoxitin cures uncomplicated gonococcal urethritis caused by penicillinase-producing Neisseria gonorrhoeae (PPNG).

Journal: Sexually transmitted diseases 19830101

Title: Treatment of gonorrhea: comparison of cefotaxime and penicillin.

Journal: Antimicrobial agents and chemotherapy 19810501

Title: Homovanilic acid in Huntington's disease and Sydenham's chorea.

Journal: Journal of neurology, neurosurgery, and psychiatry 19810301

Title: Effect of probenecid on the natriuresis and renin release induced by bumetanide in man.

Journal: Journal of clinical pharmacology 19810101

Title: Use of probenecid in ticarcillin-induced hypokalemia.

Journal: Clinical therapeutics 19800101

Title: Skin sensitizing properties of arylalcanoic acids and their analogues.

Journal: Contact dermatitis 19790901

Title: Potentiation of haloperidol-induced catalepsy by dopamine agonists: possible involvement of central 5-hydroxytryptamine.

Journal: Pharmacology, biochemistry, and behavior 19790401

Title: Transient hyperkinesia after a single intravenous perfusion of diphenylhydantoin. Report of a case associated with nontoxic plasma levels of diphenylhydantoin.

Journal: European neurology 19790101

Title: Studies on the modification of renal lesions due to aspirin and oxyphenbutazone in the rat and the effects on the kidney of 2:4 dinitrophenol.

Journal: Pathology 19760701

Title: Cephalexin-related nephropathy.

Journal: JAMA 19751110

Title: Penicillin-induced immune hemolytic anemia. Occurrence of massive intravascular hemolysis.

Journal: JAMA 19750804

Title: Relationship between the transport and toxicity of cephalosporins in the kidney.

Journal: The Journal of infectious diseases 19750801

Title: Letter: Visual defect from chloroquine phosphate.

Journal: Archives of dermatology 19750801

Title: Letter: Drug-induced red cell aplasia.

Journal: British medical journal 19741019

Title: Acute Heinz-body anaemia in burned patients.

Journal: Lancet (London, England) 19730901

Title: Probenecid-induced nephrotic syndrome.

Journal: Archives of pathology 19720901

Title: Haematuria during methicillin therapy.

Journal: Postgraduate medical journal 19710701

Title: Complications in a patient with subacute bacterial endocarditis with particular reference to massive penicillin therapy.

Journal: The Medical journal of Australia 19690621

Title: Probenecid and renal failure.

Journal: British medical journal 19680907

Title: Penicillin-induced haemolytic anaemia.

Journal: British medical journal 19680907

Title: Probenecid, nephrotic syndrome, and renal failure.

Journal: Annals of the rheumatic diseases 19680501

Title: Neurotoxicity and 'massive' intravenous therapy with penicillin. A study of possible predisposing factors.

Journal: Archives of internal medicine 19670701

Title: Nephrotic syndrome caused by probenecid.

Journal: JAMA 19670102

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Title: Greene TA, et al. Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLoS One. 2011;6(5):e20123.

Title: Silverman W, et al. Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol. 2008 Sep;295(3):C761-7.

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Tags:57-66-9 Molecular Formula|57-66-9 MDL|57-66-9 SMILES|57-66-9 4-(dipropylsulfamoyl)benzoic acid