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57757-57-0,MFCD00042045
Catalog No.:AA003IB4
57757-57-0 | Di(n-succinimidyl) 3,3'-dithiodipropionate
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100mg
97%(HPLC)
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$116.00   $81.00
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250mg
97%(HPLC)
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$203.00   $142.00
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1g
97%(HPLC)
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5g
97%(HPLC)
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  • Technical Information
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Technical Information
Catalog Number:
AA003IB4
Chemical Name:
Di(n-succinimidyl) 3,3'-dithiodipropionate
CAS Number:
57757-57-0
Molecular Formula:
C14H16N2O8S2
Molecular Weight:
404.4154
MDL Number:
MFCD00042045
IUPAC Name:
(2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoate
InChI:
InChI=1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
InChI Key:
FXYPGCIGRDZWNR-UHFFFAOYSA-N
SMILES:
O=C(ON1C(=O)CCC1=O)CCSSCCC(=O)ON1C(=O)CCC1=O
EC Number:
260-931-5
UNII:
EVY5D0U6SH
NSC Number:
328386
Properties
Computed Properties
 
Complexity:
552  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
404.035g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
404.408g/mol
Monoisotopic Mass:
404.035g/mol
Rotatable Bond Count:
11  
Topological Polar Surface Area:
178A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.2  

Synonyms
 
3,3'-dithio(succinimidyl propionate) 
3,3'-dithiobis(N-hydroxysuccinimidylpropionate) 
dithiobis(succinimidyl-propionate) 
dithiobis(succinimidylpropionate) 
dithiobis(succinimidylpropionate), 35S-labeled 
DSP cross linker 
DTBSP 
DTSP 
Lomant's reagent 
propanoic acid, 3,3'-dithiobis-, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester 
57757-57-0 
Di(N-succinimidyl) 3,3'-dithiodipropionate 
3,3'-dithiobis(propionic acid hydroxysuccinimide ester) 
Dithiobis(succinimidylpropionate) 
DSP Crosslinker 
UNII-EVY5D0U6SH 
DTSP 
Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-disulfanediyldipropanoate 
EVY5D0U6SH 
3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester) 
NSC328386 
2,5-Pyrrolidinedione, 1,1'-(dithiobis((1-oxo-3,1-propanediyl)oxy))bis- 
3,3'-Dithiopropionic acid di(N-succinimidyl ester) 
3,3'-dithiobis(succinimidyl propionate) 
Di(N-succinimidyl) 3,3-Dithiodipropionate [Cross-linking Reagent] 
Lomant's reagent 
2,5-Pyrrolidinedione, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis- 
(2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxo-propyl]disulfanyl]propanoate 
2,5-dioxopyrrolidin-1-yl 3-({3-[(2,5-dioxopyrrolidin-1-yl)oxy]-3-oxopropyl}disulfanyl)propanoate 
Disuccinimido dithiobispropionate 
DTSP crosslinker 
DSP cross-linker 
EINECS 260-931-5 
NSC 328386 
3,3'-dithiodipropionic acid disuccinimide ester 
AC1Q6LLA 
AC1L3PY7 
SCHEMBL43720 
BICL102 
DTXSID00206449 
FXYPGCIGRDZWNR-UHFFFAOYSA-N 
ZX-AFC001611 
6600AH 
ANW-43418 
MFCD00042045 
3,3'-dithioldipropionic acid bis(N-hydroxysuccinimide ester) 
ZINC76945194 
AKOS015894391 
GS-5670 
MCULE-4495083521 
NSC-328386 
AN-39846 
BP-22658 
Lomant inverted exclamation mark s reagent 
TR-020136 
D2473 
bis(2-((succinimidyloxy)carbonyl)ethyl) disulfide 
FT-0625369 
ST51016044 
KS-00001623 
A-8917 
757D570 
C-47462 
I04-9215 
3,3'-Dithiodipropionic Acid Di(N-succinimidyl Ester) 
Dithio-bis-succinimidyl propionate (Lomant's Reagent) 
3,3'-Dithiodipropionic Acid Bis(N-succinimidyl Ester) 
disuccinimido dithiobispropionate 
3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester), powder 
Di(N-succinimidyl) 3,3 inverted exclamation marka-dithiodipropionate 
Di(N-succinimidyl)3,3'-Dithiodipropionate[Cross-linkingReagent] 
1,1'-{-disulphanediylbis[(1-oxopropane-3,1-diyl)oxy]}dipyrrolidine-2,5-dione 
1,1'-{disulphanediylbis[(1-oxopropane-3,1-diyl)oxy]}dipyrrolidine-2,5-dione 
2,5-dioxoazolidinyl 3-({2-[(2,5-dioxoazolidinyl)oxycarbonyl]ethyl}disulfanyl)p ropanoate 
3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester), >=97.0% (HPLC) 
(2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoate 
1-((3-((3-((2,5-Dioxo-1-pyrrolidinyl)oxy)-3-oxopropyl)dithio)propanoyl)oxy)-2,5-pyrrolidinedione 
C14H16N2O8S2 
dithio bis(succinimidyl propionate) 
Dithiobis(succinimidyl propionate) 
CID93313 
AR-1D4592 
C14-H16-N2-O8-S2 
(DTSP);Dithio-bis-succinimidyl propionate 
3,3-DITHIODIPROPIONICACIDDI(N-SUCCINIMIDYLESTER) 
Di(N-succinimidyl) 3,3'-dithiodipropionate, 97% - 1G 1g 
5949-95-1 
885168-20-7 
DSP 
dithiobis((succinimidyl)propionate) 
Literature

Title: Simple, sensitive and selective detection of dopamine using dithiobis(succinimidylpropionate)-modified gold nanoparticles as colorimetric probes.

Journal: The Analyst 20120821

Title: Influence of macroporous gold support and its functionalization on lactate oxidase-based biosensors response.

Journal: Talanta 20120530

Title: Probe functionalization with a Rhop-3 antibody: toward a Rhop-3 antigen immunosensor for detection of malaria.

Journal: Analytical and bioanalytical chemistry 20120301

Title: Chemically immobilized T4-bacteriophage for specific Escherichia coli detection using surface plasmon resonance.

Journal: The Analyst 20110207

Title: Antibody functionalized interdigitated micro-electrode (IDmicroE) based impedimetric cortisol biosensor.

Journal: The Analyst 20100801

Title: Dithiobis(succinimidyl propionate) modified gold microarray electrode based electrochemical immunosensor for ultrasensitive detection of cortisol.

Journal: Biosensors & bioelectronics 20100615

Title: Nanostructured rough gold electrodes for the development of lactate oxidase-based biosensors.

Journal: Biosensors & bioelectronics 20100515

Title: Isolation of labile multi-protein complexes by in vivo controlled cellular cross-linking and immuno-magnetic affinity chromatography.

Journal: Journal of visualized experiments : JoVE 20100101

Title: Revisit the complexation of PEI and DNA - how to make low cytotoxic and highly efficient PEI gene transfection non-viral vectors with a controllable chain length and structure?

Journal: Journal of controlled release : official journal of the Controlled Release Society 20091116

Title: Pre-fertilization zona pellucida hardening by different cross-linkers affects IVF in pigs and cattle and improves embryo production in pigs.

Journal: Reproduction (Cambridge, England) 20090501

Title: Disulfide-linked, gold nanoparticle based reagent for detecting small molecular weight thiols.

Journal: Journal of the American Chemical Society 20090225

Title: Detection of the superoxide radical anion using various alkanethiol monolayers and immobilized cytochrome c.

Journal: Analytical chemistry 20081215

Title: Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane.

Journal: The Journal of biological chemistry 20071026

Title: Dithiobissuccinimidyl propionate self assembled monolayer based cholesterol biosensor.

Journal: The Analyst 20071001

Title: Successful co-immunoprecipitation of Oct4 and Nanog using cross-linking.

Journal: Biochemical and biophysical research communications 20070928

Title: Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes.

Journal: Biochemistry 20070703

Title: Stabilized nanocarriers for plasmids based upon cross-linked poly(ethylene imine).

Journal: Biomacromolecules 20061201

Title: Intracellular nanosphere subunit assembly as revealed by amelogenin molecular cross-linking studies.

Journal: European journal of oral sciences 20060501

Title: Atomic force microscopy and confocal laser scanning microscopy on the cytoskeleton of permeabilised and embedded cells.

Journal: Ultramicroscopy 20060301

Title: Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.

Journal: The Journal of biological chemistry 20050923

Title: Functional characterization of rhodopsin monomers and dimers in detergents.

Journal: The Journal of biological chemistry 20041224

Title: Guanidinium chloride denaturation of the dimeric Bacillus licheniformis BlaI repressor highlights an independent domain unfolding pathway.

Journal: The Biochemical journal 20041115

Title: Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.

Journal: Platelets 20040201

Title: Lateral membrane protein associations of CD4 in lymphoid cells detected by cross-linking and mass spectrometry.

Journal: Biochemistry 20040113

Title: Cross-linking approach to affinity capture of protein complexes from chaotrope-solubilized cell lysates.

Journal: Analytical biochemistry 20040101

Title: The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes.

Journal: Molecular membrane biology 20040101

Title: Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae.

Journal: Biochemistry 20031021

Title: The spatial organization of apolipoprotein A-I on the edge of discoidal high density lipoprotein particles: a mass specrometry study.

Journal: The Journal of biological chemistry 20030718

Title: Fibronectin fragments active in chondrocytic chondrolysis can be chemically cross-linked to the alpha5 integrin receptor subunit.

Journal: Osteoarthritis and cartilage 20021201

Title: Cross-linking of the endogenous inhibitor protein (IF1) with rotor (gamma, epsilon) and stator (alpha) subunits of the mitochondrial ATP synthase.

Journal: Journal of bioenergetics and biomembranes 20021201

Title: Role of Erv29p in collecting soluble secretory proteins into ER-derived transport vesicles.

Journal: Science (New York, N.Y.) 20011116

Title: Physical interactions between DinI and RecA nucleoprotein filament for the regulation of SOS mutagenesis.

Journal: The EMBO journal 20010301

Title: The channel-forming protein proaerolysin remains a dimer at low concentrations in solution.

Journal: The Journal of biological chemistry 20010105

Title: Effect of carotenoids on the interaction between pigment-protein complexes in membranes of the sulfur photosynthetic bacterium Chromatium minutissimum.

Journal: Doklady. Biochemistry and biophysics 20010101

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