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592-88-1,MFCD00008658
Catalog No.:AA003NN7

592-88-1 | Diallyl sulfide

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1g
98%(GC)
in stock  
$24.00   $17.00
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5g
98%(GC)
in stock  
$34.00   $24.00
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25g
≥95%
in stock  
$48.00   $33.00
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50g
≥95%
in stock  
$86.00   $60.00
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100g
≥95%
in stock  
$129.00   $90.00
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500g
98%
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$581.00   $407.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NN7
Chemical Name:
Diallyl sulfide
CAS Number:
592-88-1
Molecular Formula:
C6H10S
Molecular Weight:
114.2086
MDL Number:
MFCD00008658
SMILES:
C=CCSCC=C
NSC Number:
20947
FEMA Number:
2042
Properties
Properties
 
BP:
138.6°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
49.2  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.2  

Literature

Title: In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication.

Journal: Toxicology letters 20180801

Title: International Union of Basic and Clinical Pharmacology. CII: Pharmacological Modulation of H(2)S Levels: H(2)S Donors and H(2)S Biosynthesis Inhibitors.

Journal: Pharmacological reviews 20171001

Title: [Roles of CYP2E1 in liver damage induced by 1,2-dichloroethane].

Journal: Wei sheng yan jiu = Journal of hygiene research 20160301

Title: [Inhibition of pulmonary nuclear factor -ΚB and tumor necrosis factor -α expression by diallyl sulfide in rats with paraquat poisoning].

Journal: Zhonghua wei zhong bing ji jiu yi xue 20150401

Title: Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140601

Title: Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.

Journal: Environmental toxicology 20130901

Title: Diallylsulfide attenuates excessive collagen production and apoptosis in a rat model of bleomycin induced pulmonary fibrosis through the involvement of protease activated receptor-2.

Journal: Toxicology and applied pharmacology 20130901

Title: Garlic oil attenuated nitrosodiethylamine-induced hepatocarcinogenesis by modulating the metabolic activation and detoxification enzymes.

Journal: International journal of biological sciences 20130101

Title: Effects of garlic and ginger oils on hematological and biochemical variables of sea bass Dicentrarchus labrax.

Journal: Journal of aquatic animal health 20121201

Title: Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1.

Journal: Biochemical pharmacology 20121115

Title: Efficacy and tolerability of diphenyl-dimethyl-dicarboxylate plus garlic oil in patients with chronic hepatitis.

Journal: International journal of clinical pharmacology and therapeutics 20121101

Title: Novel dental restorative materials having low polymerization shrinkage stress via stress relaxation by addition-fragmentation chain transfer.

Journal: Dental materials : official publication of the Academy of Dental Materials 20121101

Title: Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria.

Journal: Toxicology letters 20121017

Title: Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression.

Journal: Annals of the New York Academy of Sciences 20121001

Title: Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.

Journal: Chemical research in toxicology 20120917

Title: Hormonal and chemical regulation of paraoxonases in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20120901

Title: Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms.

Journal: The Journal of antimicrobial chemotherapy 20120801

Title: Experimental study on inhibitory effects of diallyl sulfide on growth and invasion of human osteosarcoma MG-63 cells.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120801

Title: Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC).

Journal: Bioorganic & medicinal chemistry 20120701

Title: Transcription factor-mediated regulation of carboxylesterase enzymes in livers of mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120601

Title: Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120515

Title: Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes.

Journal: The Journal of biological chemistry 20120504

Title: Trials for the control of trichodinosis and gyrodactylosis in hatchery reared Oreochromis niloticus fries by using garlic.

Journal: Veterinary parasitology 20120430

Title: Effects of different garlic-derived allyl sulfides on peroxidative processes and anaerobic sulfur metabolism in mouse liver.

Journal: Phytotherapy research : PTR 20120301

Title: Diallyl trisulfide suppresses the adipogenesis of 3T3-L1 preadipocytes through ERK activation.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Title: Effect of garlic sulfur compounds on neutrophil infiltration and damage to the intestinal mucosa by endotoxin in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Title: Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Title: Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway.

Journal: Journal of agricultural and food chemistry 20120111

Title: Neuroprotective effects of diallyl sulfide against transient focal cerebral ischemia via anti-apoptosis in rats.

Journal: Neurological research 20120101

Title: Greco-arab and islamic herbal-derived anticancer modalities: from tradition to molecular mechanisms.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.

Journal: International journal of nanomedicine 20120101

Title: Procyanidins from wild grape (Vitis amurensis) seeds regulate ARE-mediated enzyme expression via Nrf2 coupled with p38 and PI3K/Akt pathway in HepG2 cells.

Journal: International journal of molecular sciences 20120101

Title: A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma.

Journal: PloS one 20120101

Title: Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats.

Journal: International journal of biological sciences 20120101

Title: Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae).

Journal: International journal of molecular sciences 20120101

Title: Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.

Journal: PloS one 20120101

Title: Glutathione homeostasis and functions: potential targets for medical interventions.

Journal: Journal of amino acids 20120101

Title: Pharmacokinetic interaction of garlic and atorvastatin in dyslipidemic rats.

Journal: Indian journal of pharmacology 20120101

Title: Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway.

Journal: PloS one 20120101

Title: Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen.

Journal: Molecular vision 20120101

Title: Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

Journal: International journal of molecular sciences 20120101

Title: Transformation of synthetic allicin: the influence of ultrasound, microwaves, different solvents and temperatures, and the products isolation.

Journal: TheScientificWorldJournal 20120101

Title: Homeostatic imbalance and colon cancer: the dynamic epigenetic interplay of inflammation, environmental toxins, and chemopreventive plant compounds.

Journal: Frontiers in oncology 20120101

Title: The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Modifying effect of diallyl sulfide on colon carcinogenesis in C57BL/6J-ApcMin/⁺ mice.

Journal: Asian Pacific journal of cancer prevention : APJCP 20120101

Title: Para-nitrophenol hydroxylation by fish liver microsomes: kinetics and effect of selective cytochrome P450 inhibitors.

Journal: Fish physiology and biochemistry 20111201

Title: Determination and study on dissipation of 1-naphthylacetic acid in garlic and soil using high performance liquid chromatography-tandem mass spectrometry.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111101

Title: Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.

Journal: Disease models & mechanisms 20110901

Title: Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice.

Journal: Toxicology and applied pharmacology 20110815

Title: Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: evidence for inhibition of activated MAPKs/NF-κB and reduced cell proliferation.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

Title: Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec).

Journal: The British journal of nutrition 20110701

Title: Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways.

Journal: International journal of oncology 20110601

Title: Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis.

Journal: Photodermatology, photoimmunology & photomedicine 20110601

Title: Infrared and Raman spectroscopic studies of the antimicrobial effects of garlic concentrates and diallyl constituents on foodborne pathogens.

Journal: Analytical chemistry 20110601

Title: Potential beneficial effects of garlic in oncohematology.

Journal: Mini reviews in medicinal chemistry 20110601

Title: Effect of garlic-derived allyl sulphides on morphogenesis and hydrolytic enzyme secretion in Candida albicans.

Journal: Medical mycology 20110501

Title: Polyol profile as an early diagnostic and prognostic marker in natural product chemoprevention of hepatocellular carcinoma in diabetic rats.

Journal: Diabetes research and clinical practice 20110501

Title: Effects of diallyl sulphide in chondrocyte and cartilage in experimental osteoarthritis in rabbit.

Journal: Phytotherapy research : PTR 20110301

Title: Nutraceutical inhibition of muscle proteolysis: a role of diallyl sulphide in the treatment of muscle wasting.

Journal: Clinical nutrition (Edinburgh, Scotland) 20110201

Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

Journal: International journal of molecular sciences 20110101

Title: The relaxant effect induced by Allium sativum L. bulb aqueous extract on rat isolated trachea.

Journal: Pharmacognosy magazine 20110101

Title: Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver.

Journal: PloS one 20110101

Title: Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

Journal: Clinical and experimental gastroenterology 20110101

Title: Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Garlic Oil Alleviates MAPKs- and IL-6-mediated Diabetes-related Cardiac Hypertrophy in STZ-induced DM Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: The Aqueous Soluble Polyphenolic Fraction of Psidium guajava Leaves Exhibits Potent Anti-Angiogenesis and Anti-Migration Actions on DU145 Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.

Journal: PloS one 20110101

Title: Ameliorative effects of dimetylthiourea and N-acetylcysteine on nanoparticles induced cyto-genotoxicity in human lung cancer cells-A549.

Journal: PloS one 20110101

Title: Protective effect of an aphrodisiac herb Tribulus terrestris Linn on cadmium-induced testicular damage.

Journal: Indian journal of pharmacology 20110101

Title: Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.

Journal: Clinical epigenetics 20110101

Title: Cardiac contractile dysfunction and apoptosis in streptozotocin-induced diabetic rats are ameliorated by garlic oil supplementation.

Journal: Journal of agricultural and food chemistry 20101013

Title: Aquaporin-4 knockout enhances astrocyte toxicity induced by 1-methyl-4-phenylpyridinium ion and lipopolysaccharide via increasing the expression of cytochrome P4502E1.

Journal: Toxicology letters 20101005

Title: Covalent adaptable networks as dental restorative resins: stress relaxation by addition-fragmentation chain transfer in allyl sulfide-containing resins.

Journal: Dental materials : official publication of the Academy of Dental Materials 20101001

Title: Effect of diallyldisulphide on an antioxidant enzyme system in Candida species.

Journal: Canadian journal of microbiology 20101001

Title: Optimizing the use of garlic oil as antimicrobial agent on fresh-cut tomato through a controlled release system.

Journal: Journal of food science 20100901

Title: Abstracts of the 5(th) Cachexia Conference, Barcelona, Spain, December 5-8, 2009.

Journal: Journal of cachexia, sarcopenia and muscle 20100901

Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

Journal: Journal of medicinal chemistry 20100722

Title: Garlic oil as a modulating agent for oxidative stress and neurotoxicity induced by sodium nitrite in male albino rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

Title: Negligible effect of oral garlic oil on the oral absorption of pyridoxine in metadoxine in rats.

Journal: Archives of pharmacal research 20100701

Title: Highly efficient catalytic dehydrative S-allylation of thiols and thioic S-acids.

Journal: Chemical communications (Cambridge, England) 20100614

Title: Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis.

Journal: Journal of agricultural and food chemistry 20100609

Title: Garlic components inhibit angiotensin II-induced cell-cycle progression and migration: Involvement of cell-cycle inhibitor p27(Kip1) and mitogen-activated protein kinase.

Journal: Molecular nutrition & food research 20100601

Title: Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules.

Journal: European journal of medicinal chemistry 20100501

Title: Diallyl sulfide induces growth inhibition and apoptosis of anaplastic thyroid cancer cells by mitochondrial signaling pathway.

Journal: Oral oncology 20100401

Title: The production of pork with garlic flavour notes using garlic essential oil.

Journal: Meat science 20100401

Title: Potential use of liposomal diallyl sulfide in the treatment of experimental murine candidiasis.

Journal: Bioscience reports 20100312

Title: The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat.

Journal: Alcohol (Fayetteville, N.Y.) 20100301

Title: The antioxidant role of oral administration of garlic oil on renal ischemia-reperfusion injury.

Journal: Renal failure 20100101

Title: Oxidative stress in NSC-741909-induced apoptosis of cancer cells.

Journal: Journal of translational medicine 20100101

Title: Effects of garlic oil on the migration of neutrophil-like cell studied by using a chemotactic gradient Labchip.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Redox regulation in cancer: a double-edged sword with therapeutic potential.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Reversal of hypermethylation and reactivation of the RARβ2 gene by natural compounds in cervical cancer cell lines.

Journal: Folia biologica 20100101

Title: Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action.

Journal: BMC musculoskeletal disorders 20100101

Title: The allylic chalcogen effect in olefin metathesis.

Journal: Beilstein journal of organic chemistry 20100101

Title: Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model.

Journal: Mediators of inflammation 20100101

Title: Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice.

Journal: The Libyan journal of medicine 20100101

Title: Modulation of ascorbic acid metabolism by cytochrome P450 induction revealed by metabonomics and transcriptional profiling.

Journal: Magnetic resonance in chemistry : MRC 20091201

Title: Diallyl sulfide inhibits murine WEHI-3 leukemia cells in BALB/c mice in vitro and in vivo.

Journal: Human & experimental toxicology 20091201

Title: The modulatory effects of garlic oil on hepatic cytochrome P450s in mice.

Journal: Human & experimental toxicology 20091201

Title: Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.

Journal: Chemico-biological interactions 20091110

Title: Efficacy of niosomal formulation of diallyl sulfide against experimental candidiasis in Swiss albino mice.

Journal: Nanomedicine (London, England) 20091001

Title: The garlic ingredient diallyl sulfide induces Ca(2+) mobilization in Madin-Darby canine kidney cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901

Title: Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20090701

Title: Antimicrobial activity of elephant garlic oil against Vibrio cholerae in vitro and in a food model.

Journal: Bioscience, biotechnology, and biochemistry 20090701

Title: The molecular mechanisms of diallyl disulfide and diallyl sulfide induced hepatocyte cytotoxicity.

Journal: Chemico-biological interactions 20090615

Title: Garlic: nature's protection against physiological threats.

Journal: Critical reviews in food science and nutrition 20090601

Title: Diallyl sulfides in garlic activate both TRPA1 and TRPV1.

Journal: Biochemical and biophysical research communications 20090508

Title: [Effects of garlic oil on n-hexane metabolized to 2, 5-hexanedione in mice serum].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20090501

Title: Diallyl trisulfide selectively causes Bax- and Bak-mediated apoptosis in human lung cancer cells.

Journal: Environmental and molecular mutagenesis 20090401

Title: Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis.

Journal: Phytotherapy research : PTR 20090401

Title: Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090401

Title: Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.

Journal: Environmental and molecular mutagenesis 20090401

Title: Apoptosis induction in human lung adenocarcinoma cells by oil-soluble allyl sulfides: triggers, pathways, and modulators.

Journal: Environmental and molecular mutagenesis 20090401

Title: Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells.

Journal: Growth factors (Chur, Switzerland) 20090401

Title: Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.

Journal: European journal of pharmacology 20090315

Title: Coactivity of sulfide ingredients: a new perspective of the larvicidal activity of garlic essential oil against mosquitoes.

Journal: Pest management science 20090301

Title: Comparative effects of natural and synthetic diallyl disulfide on apoptosis of human breast-cancer MCF-7 cells.

Journal: Biotechnology and applied biochemistry 20090201

Title: Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090201

Title: [Natural compounds in chemoprevention of esophageal squamous cell tumors--experimental studies].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090201

Title: Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta.

Journal: Osteoarthritis and cartilage 20090101

Title: In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress.

Journal: International journal of biological sciences 20090101

Title: Chronic crude garlic-feeding modified adult male rat testicular markers: mechanisms of action.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB.

Journal: Arthritis research & therapy 20090101

Title: Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure.

Journal: Oxidative medicine and cellular longevity 20090101

Title: Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes.

Journal: Toxicology letters 20081215

Title: Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081201

Title: Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines.

Journal: Biologics : targets & therapy 20081201

Title: The anti-fatty liver effects of garlic oil on acute ethanol-exposed mice.

Journal: Chemico-biological interactions 20081125

Title: Diallyl sulfide content and antimicrobial activity against food-borne pathogenic bacteria of chives (Allium schoenoprasum).

Journal: Bioscience, biotechnology, and biochemistry 20081101

Title: [Effects of garlic oil on 2, 5-HD induced lipid peroxidation damage in rat nerve tissues].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20081101

Title: Diallyl sulfide protects against N-nitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase.

Journal: World journal of gastroenterology 20081028

Title: Protective effects of diallyl sulfide, a garlic constituent, on the warm hepatic ischemia-reperfusion injury in a rat model.

Journal: Pharmaceutical research 20081001

Title: Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-7.

Journal: Acta pharmacologica Sinica 20081001

Title: Induction of cytochromes P450 in small intestine by chemopreventive compounds.

Journal: Neuro endocrinology letters 20081001

Title: Garlic allyl derivatives interact with membrane lipids to modify the membrane fluidity.

Journal: Journal of biomedical science 20080901

Title: Suppressive Effects of Selected Food Phytochemicals on CD74 Expression in NCI-N87 Gastric Carcinoma Cells.

Journal: Journal of clinical biochemistry and nutrition 20080901

Title: Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Diallyl sulfide inhibits PhIP-induced cell death via the inhibition of DNA strand breaks in normal human breast epithelial cells.

Journal: Oncology reports 20080801

Title: Allyl sulfides are privileged substrates in aqueous cross-metathesis: application to site-selective protein modification.

Journal: Journal of the American Chemical Society 20080730

Title: Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells.

Journal: Carcinogenesis 20080701

Title: Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: critical role of iNOS, NF-kappaB, TNF-alpha and IL-1beta.

Journal: Life sciences 20080606

Title: Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress.

Journal: Gastroenterology 20080601

Title: Organosulfur compounds alone or in combination with vitamin C protect towards N-nitrosopiperidine- and N-nitrosodibutylamine-induced oxidative DNA damage in HepG2 cells.

Journal: Chemico-biological interactions 20080509

Title: Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-kappaB, and ERK-2.

Journal: Molecular and cellular biochemistry 20080401

Title: Removal of malodorous organic sulfides with molecular oxygen and visible light over metal phthalocyanine.

Journal: Journal of hazardous materials 20080321

Title: Do garlic-derived allyl sulfides scavenge peroxyl radicals?

Journal: Organic & biomolecular chemistry 20080321

Title: Synthetic efforts for stereo structure determination of cytotoxic marine natural product pericosines as metabolites of Periconia sp. from sea hare.

Journal: International journal of molecular sciences 20080301

Title: Identification of characteristic aroma components of Thai fried chili paste.

Journal: Journal of agricultural and food chemistry 20080123

Title: Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080101

Title: Anticancer effects of diallyl trisulfide derived from garlic.

Journal: Asia Pacific journal of clinical nutrition 20080101

Title: Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine.

Journal: Cancer genomics & proteomics 20080101

Title: Regulation of oxidative stress-mediated apoptosis by diallyl sulfide in DMBA-exposed Swiss mice.

Journal: Human & experimental toxicology 20080101

Title: [Effects of garlic oil combined with resveratrol on inducting of apoptosis and expression of Fas, bcl-2 and bax in human gastric cancer cell line].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080101

Title: Effects of diallyl sulfide and zinc on testicular steroidogenesis in cadmium-treated male rats.

Journal: Journal of biochemical and molecular toxicology 20080101

Title: Redox mechanisms in hepatic chronic wound healing and fibrogenesis.

Journal: Fibrogenesis & tissue repair 20080101

Title: Gene expression analysis of biological systems driving an organotypic model of endometrial carcinogenesis and chemoprevention.

Journal: Gene regulation and systems biology 20080101

Title: Effects of garlic and juniper berry essential oils on ruminal fermentation and on the site and extent of digestion in lactating cows.

Journal: Journal of dairy science 20071201

Title: Chemoprevention of esophageal squamous cell carcinoma.

Journal: Toxicology and applied pharmacology 20071101

Title: Preventive effects of diallyl sulfide on 7,12-dimethylbenz[a]anthracene induced DNA alkylation damage in mouse skin.

Journal: Molecular nutrition & food research 20071101

Title: Role of garlic in the prevention of ischemia-reperfusion injury.

Journal: Molecular nutrition & food research 20071101

Title: Synergistic antiyeast activity of garlic oil and allyl alcohol derived from alliin in garlic.

Journal: Journal of food science 20071101

Title: Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001

Title: Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.

Journal: Biological chemistry 20071001

Title: Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070901

Title: Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells.

Journal: Cancer 20070901

Title: In vivo interactive effect of garlic oil and vitamin E against stavudine induced genotoxicity in Mus musculus.

Journal: Indian journal of experimental biology 20070901

Title: Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity.

Journal: Chemico-biological interactions 20070830

Title: Selective effects of diallyl disulfide, a sulfane sulfur precursor, in the liver and Ehrlich ascites tumor cells.

Journal: European journal of pharmacology 20070813

Title: Gender- and age-related variations in blood viscosity in normal volunteers: a study of the effects of extract of Allium sativum and Ginkgo biloba.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801

Title: [Garlic oil inhibits cyclin E expression in gastric adenocarcinoma cells].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070801

Title: Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601

Title: Two diallyl sulphides derived from garlic inhibit meticillin-resistant Staphylococcus aureus infection in diabetic mice.

Journal: Journal of medical microbiology 20070601

Title: QSAR study for the soybean 15-lipoxygenase inhibitory activity of organosulfur compounds derived from the essential oil of garlic.

Journal: Journal of agricultural and food chemistry 20070418

Title: Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells.

Journal: Apoptosis : an international journal on programmed cell death 20070401

Title: Diallyl sulfide inhibits PhIP-induced DNA strand breaks in normal human breast epithelial cells.

Journal: Oncology reports 20070401

Title: Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070301

Title: Antiangiogenic activity of Diallyl Sulfide (DAS).

Journal: International immunopharmacology 20070301

Title: Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro.

Journal: Journal of food protection 20070301

Title: Chemopreventive herbal anti-oxidants: current status and future perspectives.

Journal: Journal of clinical biochemistry and nutrition 20070301

Title: Diallyl disulfide and diallyl trisulfide up-regulate the expression of the pi class of glutathione S-transferase via an AP-1-dependent pathway.

Journal: Journal of agricultural and food chemistry 20070207

Title: Effects of garlic oil on platelet aggregation: a double-blind placebo-controlled crossover study.

Journal: Platelets 20070201

Title: Induction of total insensitivity to capsaicin and hypersensitivity to garlic extract in human by decreased expression of TRPV1.

Journal: Neuroscience letters 20070110

Title: Diallyl sulfide induces the expression of nucleotide excision repair enzymes in the breast of female ACI rats.

Journal: Toxicology letters 20070110

Title: Diallyl sulfide induces the expression of estrogen metabolizing genes in the presence and/or absence of diethylstilbestrol in the breast of female ACI rats.

Journal: Toxicology letters 20070110

Title: Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells.

Journal: Hepatology (Baltimore, Md.) 20070101

Title: Potential of diallyl sulfide bearing pH-sensitive liposomes in chemoprevention against DMBA-induced skin papilloma.

Journal: Molecular medicine (Cambridge, Mass.) 20070101

Title: CYP 2E1 mutant mice are resistant to DDC-induced enhancement of MPTP toxicity.

Journal: Journal of neural transmission. Supplementum 20070101

Title: CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation.

Journal: Experimental and molecular pathology 20061201

Title: Modulatory effects of diallyl sulfide against testosterone- induced oxidative stress in Swiss albino mice.

Journal: Asian journal of andrology 20061101

Title: Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin.

Journal: Cancer letters 20061008

Title: Different activation patterns of rat xenobiotic metabolism genes by two constituents of garlic.

Journal: Carcinogenesis 20061001

Title: Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1.

Journal: Free radical biology & medicine 20061001

Title: Increased expression of heat shock protein 72 protects renal proximal tubular cells from gentamicin-induced injury.

Journal: Journal of Korean medical science 20061001

Title: Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds.

Journal: Journal of agricultural and food chemistry 20060906

Title: A ketogenic diet and diallyl sulfide do not elevate afterdischarge thresholds in adult kindled rats.

Journal: Epilepsy research 20060901

Title: Enzymatic mechanisms of ethanol oxidation in the brain.

Journal: Alcoholism, clinical and experimental research 20060901

Title: Antidiabetic effect of garlic oil but not diallyl disulfide in rats with streptozotocin-induced diabetes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801

Title: Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20060801

Title: Garlic allyl sulfides display differential modulation of rat cytochrome P450 2B1 and the placental form glutathione S-transferase in various organs.

Journal: Journal of agricultural and food chemistry 20060712

Title: [Study of organosulfur compounds in fresh garlic by gas chromatography/mass spectrometry incorporated with temperature-programmable cold on-column injection].

Journal: Se pu = Chinese journal of chromatography 20060701

Title: The garlic ingredient diallyl sulfide inhibits cytochrome P450 2E1 dependent bioactivation of acrylamide to glycidamide.

Journal: Toxicology letters 20060620

Title: Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition.

Journal: Toxicology letters 20060601

Title: Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601

Title: Effects of garlic oil and two of its major organosulfur compounds, diallyl disulfide and diallyl trisulfide, on intestinal damage in rats injected with endotoxin.

Journal: Toxicology and applied pharmacology 20060515

Title: Molecular targets of dietary agents for prevention and therapy of cancer.

Journal: Biochemical pharmacology 20060514

Title: DATS reduces LPS-induced iNOS expression, NO production, oxidative stress, and NF-kappaB activation in RAW 264.7 macrophages.

Journal: Journal of agricultural and food chemistry 20060503

Title: Aquasonolysis of thioethers.

Journal: Ultrasonics sonochemistry 20060501

Title: Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060201

Title: Effects of garlic oil on postmenopausal osteoporosis using ovariectomized rats: comparison with the effects of lovastatin and 17beta-estradiol.

Journal: Phytotherapy research : PTR 20060101

Title: Current trends and perspectives in nutrition and cancer prevention.

Journal: Neoplasma 20060101

Title: Garlic-derived organosulfides induce cytotoxicity, apoptosis, cell cycle arrest and oxidative stress in human colon carcinoma cell lines.

Journal: Neoplasma 20060101

Title: Radioprotective activity of naturally occurring organosulfur compounds.

Journal: Tumori 20060101

Title: Cytochrome P450 and Parkinson's disease: protective role of neuronal CYP 2E1 from MPTP toxicity.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Involvement of multiple signaling pathways in diallyl sulfide mediated apoptosis in mouse skin tumors.

Journal: Asian Pacific journal of cancer prevention : APJCP 20060101

Title: Could garlic be an useful adjuvant therapy in adriamycin heart failure?

Journal: Kathmandu University medical journal (KUMJ) 20060101

Title: Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin.

Journal: The Journal of biological chemistry 20051216

Title: Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20051201

Title: Effect of garlic oil and four of its compounds on rumen microbial fermentation.

Journal: Journal of dairy science 20051201

Title: Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050901

Title: Diallyl sulfide inhibits diethylstilbesterol-induced DNA adducts in the breast of female ACI rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

Title: CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes.

Journal: World journal of gastroenterology 20050807

Title: Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: Effects of cinnamaldehyde and garlic oil on rumen microbial fermentation in a dual flow continuous culture.

Journal: Journal of dairy science 20050701

Title: Cytochrome P4502E1 primes macrophages to increase TNF-alpha production in response to lipopolysaccharide.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050701

Title: Garlic oil and DDB, comprised in a pharmaceutical composition for the treatment of patients with viral hepatitis, prevents acute liver injuries potentiated by glutathione deficiency in rats.

Journal: Chemico-biological interactions 20050630

Title: Fumigant activity of plant essential oils and components from garlic (Allium sativum) and clove bud (Eugenia caryophyllata) oils against the Japanese termite (Reticulitermes speratus Kolbe).

Journal: Journal of agricultural and food chemistry 20050601

Title: Nutraceutical effects of garlic oil, its nonpolar fraction and a Ficus flavonoid as compared to vitamin E in CCl4 induced liver damage in rats.

Journal: Indian journal of experimental biology 20050501

Title: Ultrasonic cleavage of thioethers.

Journal: The journal of physical chemistry. A 20050428

Title: Modulation of cytokine secretion by garlic oil derivatives is associated with suppressed nitric oxide production in stimulated macrophages.

Journal: Journal of agricultural and food chemistry 20050406

Title: Differential effects of organosulfur compounds from garlic oil on nitric oxide and prostaglandin E2 in stimulated macrophages.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20050401

Title: Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin.

Journal: Phytotherapy research : PTR 20050301

Title: Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.

Journal: Biochemical and biophysical research communications 20050218

Title: Beneficial effects of a polar fraction of garlic (Allium sativum Linn) oil in rats fed with two different high fat diets.

Journal: Indian journal of experimental biology 20050101

Title: Inhibition by allyl sulfides and crushed garlic of O6-methylguanine formation in liver DNA of dimethylnitrosamine-treated rats.

Journal: Nutrition and cancer 20050101

Title: Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba.

Journal: Drugs & aging 20050101

Title: ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.

Journal: Cancer cell international 20050101

Title: [Evaluation of repellent and anti-feeding effect of garlic oil (Allium sativum) against the bite of phlebotomine sandflies Diptera: Psychodidae].

Journal: Annali dell'Istituto superiore di sanita 20050101

Title: Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Journal: Virology journal 20050101

Title: Effect of combined supplementation of fish oil with garlic pearls on the serum lipid profile in hypercholesterolemic subjects.

Journal: Indian heart journal 20050101

Title: Diallyl sulfide induces heme oxygenase-1 through MAPK pathway.

Journal: Archives of biochemistry and biophysics 20041215

Title: Differential effects of allyl sulfides from garlic essential oil on cell cycle regulation in human liver tumor cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041201

Title: Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Role of chemopreventive agents in cancer therapy.

Journal: Cancer letters 20041125

Title: Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review.

Journal: Mutation research 20041102

Title: Modulation of p53 in 7,12-dimethylbenz[a]anthracene-induced skin tumors by diallyl sulfide in Swiss albino mice.

Journal: Molecular cancer therapeutics 20041101

Title: Inhibition of the benzo[a]pyrene-induced toxicity by allyl sulfides in human epidermal keratinocytes.

Journal: Biotechnology letters 20041101

Title: Antioxidant effects of sulfur-containing amino acids.

Journal: Yonsei medical journal 20041031

Title: Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.

Journal: Journal of neurochemistry 20041001

Title: Post-initiation modulating effects of allyl sulfides in rat hepatocarcinogenesis.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040901

Title: Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats.

Journal: Journal of ethnopharmacology 20040901

Title: Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20040801

Title: Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2.

Journal: Oncogene 20040722

Title: Antioxidative and antiglycative effects of six organosulfur compounds in low-density lipoprotein and plasma.

Journal: Journal of agricultural and food chemistry 20040602

Title: Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver.

Journal: Carcinogenesis 20040601

Title: Spice phenolics inhibit human PMNL 5-lipoxygenase.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040601

Title: Solid-phase microextraction-gas chromatographic-mass spectrometric analysis of garlic oil obtained by hydrodistillation.

Journal: Journal of chromatography. A 20040514

Title: Diallyl sulfide inhibits the oxidation and reduction reactions of stilbene estrogens catalyzed by microsomes, mitochondria and nuclei isolated from breast tissue of female ACI rats.

Journal: Carcinogenesis 20040501

Title: The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040501

Title: [Gladness and troubles for using garlic as an anti-oxidant].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040501

Title: Aversion of European starlings (Sturnus vulgaris) to garlic oil treated granules: garlic oil as an avian repellent. Garlic oil analysis by nuclear magnetic resonance spectroscopy.

Journal: Journal of agricultural and food chemistry 20040421

Title: Organosulfur compounds from alliaceae in the prevention of human pathologies.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20040401

Title: Inhibitory activity of essential oils of garlic and onion against bacteria and yeasts.

Journal: Journal of food protection 20040301

Title: Role of cytochrome P4502E1 activation in proximal tubular cell injury induced by hydrogen peroxide.

Journal: Renal failure 20040301

Title: Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201

Title: Garlic metabolites fail to inhibit the activation of the transcription factor NF-kappaB and subsequent expression of the adhesion molecule E-selectin in human endothelial cells.

Journal: European journal of nutrition 20040201

Title: Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3.

Journal: Nutrition and cancer 20040101

Title: Garlic's ability to prevent in vitro Cu2+-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu2+-chelation.

Journal: Nutrition journal 20040101

Title: Inhibition of cyclooxygenase-2 by diallyl sulfides (DAS) in HEK 293T cells.

Journal: Journal of applied genetics 20040101

Title: Anticarcinogenic properties of garlic: a review.

Journal: Critical reviews in food science and nutrition 20040101

Title: Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus.

Journal: Nutrition and cancer 20040101

Title: Diallyl sulfide depletes the inositol trisphosphate-sensitive intracellular Ca2+ stores and activates SOC-channels in HL-60 human cells.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101

Title: Toxicological assessment of noxious inhalants.

Journal: GMS current topics in otorhinolaryngology, head and neck surgery 20040101

Title: Garlic extract and two diallyl sulphides inhibit methicillin-resistant Staphylococcus aureus infection in BALB/cA mice.

Journal: The Journal of antimicrobial chemotherapy 20031201

Title: Protective effect of diallyl sulfide on oxidative stress and nephrotoxicity induced by gentamicin in rats.

Journal: Molecular and cellular biochemistry 20031201

Title: Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: Comparative study of extraction techniques for determination of garlic flavor components by gas chromatography-mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20031001

Title: Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030901

Title: Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury.

Journal: Pharmacological research 20030801

Title: Doyle-Kirmse reaction of allylic sulfides with diazoalkane-free (2-furyl)carbenoid transfer.

Journal: Organic letters 20030724

Title: Diallylsulfide attenuates asbestos-induced genotoxicity.

Journal: Toxicology letters 20030605

Title: The inhibition of superoxide production in EL4 lymphoma cells overexpressing growth hormone.

Journal: Immunopharmacology and immunotoxicology 20030501

Title: Short-term acetaldehyde exposure depresses ventricular myocyte contraction: role of cytochrome P450 oxidase, xanthine oxidase, and lipid peroxidation.

Journal: Alcoholism, clinical and experimental research 20030401

Title: Protective action on human LDL against oxidation and glycation by four organosulfur compounds derived from garlic.

Journal: Lipids 20030301

Title: The combined effects of garlic oil and fish oil on the hepatic antioxidant and drug-metabolizing enzymes of rats.

Journal: The British journal of nutrition 20030201

Title: Interactions of herbs with cytochrome P450.

Journal: Drug metabolism reviews 20030201

Title: Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit.

Journal: Hepatology (Baltimore, Md.) 20030101

Title: Antigenotoxic potential of certain dietary constituents.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20030101

Title: Mechanism-based in vitro screening of potential cancer chemopreventive agents.

Journal: Mutation research 20030101

Title: Diallyl sulfide inhibits diethylstilbestrol-induced lipid peroxidation in breast tissue of female ACI rats: implications in breast cancer prevention.

Journal: Oncology reports 20030101

Title: Inhibition of DES-induced DNA adducts by diallyl sulfide: implications in liver cancer prevention.

Journal: Oncology reports 20030101

Title: Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.

Journal: Nutrition and cancer 20030101

Title: Prevention of chemical carcinogen DNA binding and inhibition of nuclear RNA polymerase activity by organosulfur compounds as the possible mechanisms for their anticancer initiation and proliferation effects.

Journal: Cancer detection and prevention 20030101

Title: Antioxidant and antimicrobial effects of four garlic-derived organosulfur compounds in ground beef.

Journal: Meat science 20030101

Title: Protective effect of three diallyl sulphides against glucose-induced erythrocyte and platelet oxidation, and ADP-induced platelet aggregation.

Journal: Thrombosis research 20021215

Title: Alleviation of cyclophosphamide-induced urotoxicity by naturally occurring sulphur compounds.

Journal: Journal of experimental & clinical cancer research : CR 20021201

Title: Inhibition of heterocyclic aromatic amine formation in fried ground beef patties by garlic and selected garlic-related sulfur compounds.

Journal: Journal of food protection 20021101

Title: Nonenzymatic antioxidant activity of four organosulfur compounds derived from garlic.

Journal: Journal of agricultural and food chemistry 20021009

Title: Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic.

Journal: Carcinogenesis 20021001

Title: Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans.

Journal: Clinical pharmacology and therapeutics 20020901

Title: Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801

Title: Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic.

Journal: Carcinogenesis 20020801

Title: Role of endotoxin in NF-kappaB activation by ethanol in rat hepatocytes.

Journal: Alcoholism, clinical and experimental research 20020801

Title: Tissue distribution and chemical induction of multiple drug resistance genes in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701

Title: Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity.

Journal: Free radical biology & medicine 20020701

Title: Effects of food materials on removal of Allium-specific volatile sulfur compounds.

Journal: Journal of agricultural and food chemistry 20020619

Title: Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages.

Journal: Life sciences 20020614

Title: Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria.

Journal: Hepatology (Baltimore, Md.) 20020601

Title: Antitumorigenic potential of diallyl sulfide in Ehrlich ascites tumor bearing mice.

Journal: Biomedical and environmental sciences : BES 20020301

Title: Differential effects of garlic oil and its three major organosulfur components on the hepatic detoxification system in rats.

Journal: Journal of agricultural and food chemistry 20020116

Title: Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Mechanisms of circadian rhythmicity of carbon tetrachloride hepatotoxicity.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Inhibition of human low density lipoprotein oxidation by active principles from spices.

Journal: Molecular and cellular biochemistry 20020101

Title: In vivo effect of diallyl sulfide and cimetidine on phenacetin metabolism and bioavailability in rat.

Journal: Acta biochimica Polonica 20020101

Title: Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in human promyelocytic leukemia cells.

Journal: The American journal of Chinese medicine 20020101

Title: Use of factorial designs to optimize animal experiments and reduce animal use.

Journal: ILAR journal 20020101

Title: Anti-tumour-promoting action of Allium constituents.

Journal: IARC scientific publications 20020101

Title: Effect of garlic on cardiovascular disorders: a review.

Journal: Nutrition journal 20020101

Title: Induction of apoptosis by diallyl sulfide in DMBA-induced mouse skin tumors.

Journal: Nutrition and cancer 20020101

Title: Chemopreventive allylthiopyridazine derivatives induce apoptosis in SK-Hep-1 hepatocarcinoma cells through a caspase-3-dependent mechanism.

Journal: European journal of cancer (Oxford, England : 1990) 20011101

Title: Etiology and chemoprevention of esophageal squamous cell carcinoma.

Journal: Carcinogenesis 20011101

Title: Modulation of cytochrome P4501-mediated bioactivation of benzo[a]pyrene by volatile allyl sulfides in human hepatoma cells.

Journal: Bioscience, biotechnology, and biochemistry 20011001

Title: A pilot study to determine the effectiveness of garlic oil capsules in the treatment of dyspeptic patients with Helicobacter pylori.

Journal: Helicobacter 20010901

Title: Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction.

Journal: Mutation research 20010822

Title: Cytochrome P4502E1 induction increases thioacetamide liver injury in diet-restricted rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010801

Title: Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant sub-populations.

Journal: Carcinogenesis 20010801

Title: Plant foods and risk of gastric cancer: a case-control study in Uruguay.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20010801

Title: Screening of organosulfur compounds as inhibitors of human CYP2A6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010701

Title: In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils.

Journal: Journal of medical microbiology 20010701

Title: The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone.

Journal: Human & experimental toxicology 20010701

Title: Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: a new metabolic pathway?

Journal: Synapse (New York, N.Y.) 20010615

Title: Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601

Title: Effect of diallyl sulfide and diallyl disulfide, the active principles of garlic, on the aflatoxin B(1)-induced DNA damage in primary rat hepatocytes.

Journal: Toxicology letters 20010531

Title: Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality.

Journal: Toxicology and applied pharmacology 20010515

Title: In vitro activity of garlic oil and four diallyl sulphides against antibiotic-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae.

Journal: The Journal of antimicrobial chemotherapy 20010501

Title: Diallyl sulfide--a flavour component from garlic (Allium sativum) attenuates lipid peroxidation in mice infected with Trichinella spiralis.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20010501

Title: Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.

Journal: Molecular pharmacology 20010401

Title: Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1.

Journal: Alcoholism, clinical and experimental research 20010401

Title: Effect of garlic oil on the levels of various enzymes in the serum and tissue of streptozotocin diabetic rats.

Journal: Bioscience reports 20010201

Title: CYP2E1-dependent toxicity and up-regulation of antioxidant genes.

Journal: Journal of biomedical science 20010101

Title: Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1.

Journal: Gastroenterology 20010101

Title: Antioxidants in chemoprevention of skin cancer.

Journal: Current problems in dermatology 20010101

Title: A randomized trial of the effects of garlic oil upon coronary heart disease risk factors in trained male runners.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010101

Title: Mechanisms by which garlic and allyl sulfur compounds suppress carcinogen bioactivation. Garlic and carcinogenesis.

Journal: Advances in experimental medicine and biology 20010101

Title: Inhibition of carcinogenesis and toxicity by dietary constituents.

Journal: Advances in experimental medicine and biology 20010101

Title: Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinone reductase and glutathione transferase in rat tissues.

Journal: Nutrition and cancer 20010101

Title: [Status of and prospect on experimental studies of single Chinese herb inducing tumor cell apoptosis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010101

Title: Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.

Journal: The Journal of pharmacology and experimental therapeutics 20000901

Title: Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis.

Journal: Molecular and cellular biochemistry 20000801

Title: Inhibition of CYP2E1 reverses CD4+ T-cell alterations in trichloroethylene-treated MRL+/+ mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20000401

Title: Interindividual variability in P450-dependent generation of neoantigens in halothane hepatitis.

Journal: Chemico-biological interactions 19981106

Title: Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1.

Journal: The Journal of biological chemistry 19960927

Title: Molecular mechanism for alkyl sulfide-modulated carbon tetrachloride-induced hepatotoxicity: the role of cytochrome P450 2E1, P450 2B and glutathione S-transferase expression.

Journal: The Journal of pharmacology and experimental therapeutics 19960501

Title: Cytochrome P4502E1- and cytochrome P4502B1/2B2-catalyzed carbon tetrachloride metabolism: effects on signal transduction as demonstrated by altered immediate-early (c-Fos and c-Jun) gene expression and nuclear AP-1 and NF-kappa B transcription factor levels.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19960101

Title: The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer.

Journal: Biochemical pharmacology 19951222

Title: Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions.

Journal: European journal of biochemistry 19950615

Title: Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat.

Journal: Japanese journal of cancer research : Gann 19941201

Title: Inhibition of cytochrome P4502E1 expression by organosulfur compounds allylsulfide, allylmercaptan and allylmethylsulfide in rats.

Journal: Biochemical pharmacology 19940209

Title: Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123).

Journal: Drug metabolism and disposition: the biological fate of chemicals 19940101

Title: Regulation of cytochrome P450 2B1/2 genes by diallyl sulfone, disulfiram, and other organosulfur compounds in primary cultures of rat hepatocytes.

Journal: Biochemical pharmacology 19930609

Title: Gas-uptake pharmacokinetics and biotransformation of 1,1-dichloro-1-fluoroethane (HCFC-141b).

Journal: Drug metabolism and disposition: the biological fate of chemicals 19930101

Title: A pleiotropic response to phenobarbital-type enzyme inducers in the F344/NCr rat. Effects of chemicals of varied structure.

Journal: Biochemical pharmacology 19920303

Title: Inhibition of benzoyl peroxide-mediated tumor promotion in 7,12-dimethylbenz(a)anthracene-initiated skin of Sencar mice by antioxidants nordihydroguaiaretic acid and diallyl sulfide.

Journal: The Journal of investigative dermatology 19900201

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