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595-15-3,MFCD00075988
Catalog No.:AA00ECMA

595-15-3 | Soyasapogenol B

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1mg
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$156.00   $109.00
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5mg
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$463.00   $324.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ECMA
Chemical Name:
Soyasapogenol B
CAS Number:
595-15-3
Molecular Formula:
C30H50O3
Molecular Weight:
458.7162
MDL Number:
MFCD00075988
SMILES:
OC[C@@]1(C)[C@@H](O)CC[C@]2([C@H]1CC[C@@]1([C@@H]2CC=C2[C@@]1(C)CC[C@@]1([C@H]2CC(C[C@H]1O)(C)C)C)C)C
Properties
Computed Properties
 
Complexity:
848  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
7  

Literature

Title: Soyasapogenol B and trans-22-dehydrocam- pesterol from common vetch (Vicia sativa L.) root exudates stimulate broomrape seed germination.

Journal: Pest management science 20110801

Title: Anti-inflammatory effect of soyasaponins through suppressing nitric oxide production in LPS-stimulated RAW 264.7 cells by attenuation of NF-κB-mediated nitric oxide synthase expression.

Journal: Bioorganic & medicinal chemistry letters 20110415

Title: [Apoptosis effects on human esophageal cancer cells by soyasaponin Bb and its machanism].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100701

Title: Identification and characterization of glycosyltransferases involved in the biosynthesis of soyasaponin I in Glycine max.

Journal: FEBS letters 20100603

Title: Inhibition of human renin activity by saponins.

Journal: Biomedical research (Tokyo, Japan) 20100401

Title: Enhanced triterpene saponin biosynthesis and root nodulation in transgenic barrel medic (Medicago truncatula Gaertn.) expressing a novel beta-amyrin synthase (AsOXA1) gene.

Journal: Plant biotechnology journal 20090201

Title: Effect of soyasapogenol A and soyasapogenol B concentrated extracts on HEP-G2 cell proliferation and apoptosis.

Journal: Journal of agricultural and food chemistry 20080423

Title: Cloning and characterization of saponin hydrolases from Aspergillus oryzae and Eupenicillium brefeldianum.

Journal: Bioscience, biotechnology, and biochemistry 20051101

Title: The isolation of soyasaponins by fractional precipitation, solid phase extraction, and low pressure liquid chromatography.

Journal: International journal of food sciences and nutrition 20051101

Title: Preventive effects of soyasapogenol B derivatives on liver injury in a concanavalin A-induced hepatitis model.

Journal: Bioorganic & medicinal chemistry 20050815

Title: Soyasaponins lowered plasma cholesterol and increased fecal bile acids in female golden Syrian hamsters.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050701

Title: Soyasapogenol A and B distribution in soybean (Glycine max L. Merr.) in relation to seed physiology, genetic variability, and growing location.

Journal: Journal of agricultural and food chemistry 20030924

Title: Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells.

Journal: Biological & pharmaceutical bulletin 20030901

Title: Simultaneous identification of soyasaponins and isoflavones and quantification of soyasaponin Bb in soy products, using liquid chromatography/electrospray ionization-mass spectrometry.

Journal: Journal of agricultural and food chemistry 20030604

Title: Up-regulation of soyasaponin biosynthesis by methyl jasmonate in cultured cells of Glycyrrhiza glabra.

Journal: Plant & cell physiology 20030401

Title: Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity.

Journal: Nutrition and cancer 20030101

Title: Estrogenic and antiproliferative properties of soy sapogenols in human breast cancer cells in vitro.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021201

Title: Determination of soyasaponins in soy with LC-MS following structural unification by partial alkaline degradation.

Journal: Journal of agricultural and food chemistry 20021120

Title: UDP-glucuronic acid:soyasapogenol glucuronosyltransferase involved in saponin biosynthesis in germinating soybean seeds.

Journal: Planta 20020801

Title: Analysis and quantitative determination of group B saponins in processed soybean products.

Journal: Phytochemical analysis : PCA 20020101

Title: Wang L, et al. Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer. Life Sci. 2019 Feb 1;218:16-24.

Title: Wang L, et al. Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma. Naunyn Schmiedebergs Arch Pharmacol. 2019 May;392(5):551-563.

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