Title: Autoproteolytic activation of ThnT results in structural reorganization necessary for substrate binding and catalysis.
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Title: Comparative analysis of a cryptic thienamycin-like gene cluster identified in Streptomyces flavogriseus by genome mining.
Journal: Archives of microbiology 20120601
Title: Radical-mediated enzymatic methylation: a tale of two SAMS.
Journal: Accounts of chemical research 20120417
Title: Novel carbon-carbon bond formations for biocatalysis.
Journal: Current opinion in biotechnology 20111201
Title: Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis.
Journal: Chembiochem : a European journal of chemical biology 20110919
Title: Discovery of 3-formyl-tyrosine metabolites from Pseudoalteromonas tunicata through heterologous expression.
Journal: Journal of the American Chemical Society 20100127
Title: Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics.
Journal: Journal of the American Chemical Society 20100113
Title: Current status of carbapenem antibiotics.
Journal: Current topics in medicinal chemistry 20100101
Title: Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.
Journal: Organic & biomolecular chemistry 20090707
Title: Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.
Journal: Chembiochem : a European journal of chemical biology 20090126
Title: Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster from Streptomyces cattleya.
Journal: Molecular microbiology 20080801
Title: Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).
Journal: BMC genomics 20080101
Title: Empirical antibacterial drug discovery--foundation in natural products.
Journal: Biochemical pharmacology 20060330
Title: Involvement of nitrogen-containing compounds in beta-lactam biosynthesis and its control.
Journal: Critical reviews in biotechnology 20060101
Title: Secretion systems for secondary metabolites: how producer cells send out messages of intercellular communication.
Journal: Current opinion in microbiology 20050601
Title: Regulation and biosynthesis of carbapenem antibiotics in bacteria.
Journal: Nature reviews. Microbiology 20050401
Title: Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
Journal: The Journal of biological chemistry 20040220
Title: The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya.
Journal: Chemistry & biology 20030401
Title: Recent developments in carbapenems.
Journal: Expert opinion on investigational drugs 20020401
Title: Antibiotic resistance and molecular typing of Pseudomonas aeruginosa: focus on imipenem.
Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20020201
Title: Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin.
Journal: The American journal of medicine 19850607
