Home Nitro Compounds 609-39-2
609-39-2,MFCD00013442
Catalog No.:AA003HPW
609-39-2 | 2-Nitrofuran
This product is typically in stock,please click "Inquire" below or
contact us at sales@aablocks.com for pricing and availability information.
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Q & A
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003HPW
Chemical Name:
2-Nitrofuran
CAS Number:
609-39-2
Molecular Formula:
C4H3NO3
Molecular Weight:
113.0715
MDL Number:
MFCD00013442
IUPAC Name:
2-nitrofuran
InChI:
InChI=1S/C4H3NO3/c6-5(7)4-2-1-3-8-4/h1-3H
InChI Key:
FUBFWTUFPGFHOJ-UHFFFAOYSA-N
SMILES:
[O-][N+](=O)c1ccco1
UNII:
17EZI4D981
NSC Number:
59983
Properties
Computed Properties
 
Complexity:
97.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
113.011g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
113.072g/mol
Monoisotopic Mass:
113.011g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
59A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.7  

Synonyms
 
2-NITROFURAN 
609-39-2 
BRN 0112523 
17EZI4D981 
27194-24-7 
Q-103253 
2-Nitrofuran, 97% 
AC1L1YB9 
SCHEMBL30623 
5-17-01-00296 (Beilstein Handbook Reference) 
AMOT0097 
CHEBI:34890 
Nitrofuran 
CTK1A5052 
FUBFWTUFPGFHOJ-UHFFFAOYSA-N 
BCP23236 
NSC59983 
ZINC1689931 
9109AB 
ANW-66544 
NSC-59983 
AKOS015900364 
FCH1116845 
5-Nitrofuran 
TRA0000166 
AJ-30012 
H118 
LS-70264 
DB-002205 
TC-155289 
AM20100483 
FT-0632538 
C14414 
C-51401 
Furan, 2-nitro- 
I14-0642 
2-nitro-fura;2-Nitrofurane;5-Nitrofuran;Furan, 2-nitro-; 
InChI=1/C4H3NO3/c6-5(7)4-2-1-3-8-4/h1-3 
C4H3NO3 
Diphosphoric acid, diethyl ester 
C4-H3-N-O3 
CID11865 
Furan, nitro- 
Nitrofuran (VAN) 
AI3-23606 
NSC 59983 
UNII-17EZI4D981 
Literature

Title: Tuberculosis: finding a new potential antimycobacterium derivative in a aldehyde-arylhydrazone-oxoquinoline series.

Journal: Current microbiology 20121001

Title: New mechanisms of 5-nitrofuran toxicity.

Journal: Chemistry & biology 20120727

Title: ALDH2 mediates 5-nitrofuran activity in multiple species.

Journal: Chemistry & biology 20120727

Title: Mefloquine-oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113.

Journal: Bioorganic & medicinal chemistry 20120101

Title: Protein-DNA interactions define the mechanistic aspects of circle formation and insertion reactions in IS2 transposition.

Journal: Mobile DNA 20120101

Title: DNA as molecular target of analogous palladium and platinum anti-Trypanosoma cruzi compounds: a comparative study.

Journal: Journal of inorganic biochemistry 20111201

Title: Potent 5-nitrofuran derivatives inhibitors of Trypanosoma cruzi growth: electrochemical, spectroscopic and biological studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110701

Title: Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.

Journal: The Journal of biological chemistry 20110415

Title: 2,3-Dibromo-3-(5-nitro-2-fur-yl)-1-phenyl-propan-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.

Journal: Bioorganic & medicinal chemistry 20110115

Title: 2,3-Dibromo-1-(4-methyl-phen-yl)-3-(5-nitro-furan-2-yl)propan-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents.

Journal: PloS one 20110101

Title: Mycobacterium tuberculosis acg gene is required for growth and virulence in vivo.

Journal: PloS one 20110101

Title: Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways.

Journal: PloS one 20110101

Title: [Development and use of test systems for the evaluation of sensitivity of Trichomonas vaginalisto preparations of the 5-nitroimidazole and 5-nitrofuran groups].

Journal: Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20110101

Title: Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benzonidazole in Trypanosoma cruzi.

Journal: Parasites & vectors 20110101

Title: Activation of nitrofurazone by azoreductases: multiple activities in one enzyme.

Journal: Scientific reports 20110101

Title: 2,3-Dibromo-3-(5-nitro-2-fur-yl)-1-(4-nitro-phen-yl)propan-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: 2,3-Dibromo-1-(4-chloro-phen-yl)-3-(5-nitro-2-fur-yl)propan-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: 3-(5-Nitro-2-fur-yl)-1-phenyl-prop-2-yn-1-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Susceptibility in vitro of clinically metronidazole-resistant Trichomonas vaginalis to nitazoxanide, toyocamycin, and 2-fluoro-2'-deoxyadenosine.

Journal: Parasitology research 20100901

Title: (4-Chloro-phen-yl)[1-(4-methoxy-phen-yl)-3-(5-nitro-2-fur-yl)-1H-pyrazol-4-yl]methanone.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Synthesis and antiproliferative evaluations of certain 2-phenylvinylquinoline (2-styrylquinoline) and 2-furanylvinylquinoline derivatives.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones.

Journal: European journal of medicinal chemistry 20091201

Title: (4-Methyl-phen-yl)[3-(5-nitro-2-fur-yl)-1-phenyl-1H-pyrazol-4-yl]methanone.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: 5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: preliminary in vivo studies.

Journal: European journal of medicinal chemistry 20091001

Title: E. coli NfsA: an alternative nitroreductase for prodrug activation gene therapy in combination with CB1954.

Journal: British journal of cancer 20090616

Title: 5-Nitrofuran-2-yl derivatives: synthesis and inhibitory activities against growing and dormant mycobacterium species.

Journal: Bioorganic & medicinal chemistry letters 20090215

Title: Preliminary evaluation of the toxicity of some synthetic furan derivatives in two cell lines and Artemia salina.

Journal: Journal of applied toxicology : JAT 20090101

Title: Synthesis, spectroscopic, and antimicrobial studies on bivalent zinc and mercury complexes of 2-formylpyridine thiosemicarbazone.

Journal: Bioinorganic chemistry and applications 20090101

Title: Genetic architecture of intrinsic antibiotic susceptibility.

Journal: PloS one 20090101

Title: Use of nfsB, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in Neisseria gonorrhoeae.

Journal: BMC microbiology 20090101

Title: Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.

Journal: Journal of parasitology research 20090101

Title: ESR, electrochemical and reactivity studies of antitrypanosomal palladium thiosemicarbazone complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080801

Title: Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines.

Journal: Bioorganic & medicinal chemistry 20080415

Title: Thiosemicarbazones active against Clostridium difficile.

Journal: Bioorganic & medicinal chemistry letters 20080301

Title: Insight into the bioreductive mode of action of antitrypanosomal 5-nitrofuryl containing thiosemicarbazones.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20080101

Title: Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents.

Journal: Journal of inorganic biochemistry 20080101

Title: Thanatop: a novel 5-nitrofuran that is a highly active, cell-permeable inhibitor of topoisomerase II.

Journal: Cancer research 20070501

Title: Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

Journal: Drug target insights 20070101

Title: Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060701

Title: New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies.

Journal: European journal of medicinal chemistry 20060401

Title: Conformational analyses and docking studies of a series of 5-nitrofuran- and 5-nitrothiophen-semicarbazone derivatives in three possible binding sites of trypanothione and glutathione reductases.

Journal: Journal of molecular graphics & modelling 20060301

Title: In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

Journal: Bioorganic & medicinal chemistry 20040915

Title: Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.

Journal: European journal of medicinal chemistry 20040501

Title: Analysis of 5-nitrofuran derivatives in biological objects.

Journal: Bulletin of experimental biology and medicine 20030101

Title: Investigation of 5-nitrofuran derivatives: synthesis, antibacterial activity, and quantitative structure-activity relationships.

Journal: Journal of medicinal chemistry 20011025

Title: Cytogenetic analysis of children under long-term antibacterial therapy with nitroheterocyclic compound furagin.

Journal: Mutation research 20010405

Title: Synthesis and antibacterial activity of 5-nitrofuryl and 3-methoxy-2-nitrophenyl derivatives of 6 beta-aminopenicillanic, 7 beta-aminocephalosporanic and 7 beta-aminodesacetoxy-cephalosporanic acids.

Journal: Arzneimittel-Forschung 20010101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Additional Info:
Q & A
Related Products