Home Imidazoles 615-15-6
615-15-6,MFCD00005598
Catalog No.:AA003HLV

615-15-6 | 2-Methylbenzimidazole

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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003HLV
Chemical Name:
2-Methylbenzimidazole
CAS Number:
615-15-6
Molecular Formula:
C8H8N2
Molecular Weight:
132.1625
MDL Number:
MFCD00005598
SMILES:
Cc1nc2c([nH]1)cccc2
NSC Number:
6500
Properties
Properties
 
BP:
339.4°C at 760 mmHg  
Form:
Solid  
MP:
175-177 °C(lit.)  
Refractive Index:
1.6013 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
124  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
XLogP3:
2.2  

Literature

Title: Bis(2-methyl-1H-benzimidazol-3-ium) naphthalene-1,5-disulfonate.

Journal: Acta crystallographica. Section E, Structure reports online 20121001

Title: 2-Methyl-1H-benzimidazol-3-ium hydrogen phthalate.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: 2-Chloro-methyl-1-methyl-1,3-benzimidazole.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Bis[bis-(3,5-diamino-1H-1,2,4-triazol-4-ium)copper(I)] tris-(hexa-fluoridosilicate).

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Di-μ-thio-cyanato-κN:S;κS:N-bis-[bis-(2-methyl-1H-benzimidazole-κN)(thio-cyanato-κN)cadmium(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 2-Methyl-benzimidazolium thio-cyanate.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 2-Methyl-benzimidazolium thio-cyanate-2-methyl-benzimidazole (1/1).

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Molecular structure and vibrational spectra of 2- and 5-methylbenzimidazole molecules by density functional theory.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100701

Title: Tetra-kis(2-methyl-benzimidazolium) β-octa-molybdate(VI).

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Bis[μ-2,2'-dimethyl-1,1'-(oxydiethyl-ene)bis-(1H-benzimidazole)-κN:N]bis-[bis-(4-methoxy-benzoato-κO,O')cadmium(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: 2-Methyl-benzimidazolium nitrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: 1,3-Dibenzyl-2-methyl-benzimidazolium chloride.

Journal: Acta crystallographica. Section E, Structure reports online 20100201

Title: Synthesis, characterization, and biological evaluation of benzimidazole derivatives as potential anxiolytics.

Journal: Journal of young pharmacists : JYP 20100101

Title: Cytotoxic activity, X-ray crystal structures and spectroscopic characterization of cobalt(II), copper(II) and zinc(II) coordination compounds with 2-substituted benzimidazoles.

Journal: Journal of inorganic biochemistry 20090901

Title: 2-Meth-oxy-6-(6-methyl-1H-benzimidazol-2-yl)phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: Synthesis, pharmacological screening, quantum chemical and in vitro permeability studies of N-Mannich bases of benzimidazoles through bovine cornea.

Journal: European journal of medicinal chemistry 20090501

Title: QSAR analysis of 2-amino or 2-methyl-1-substituted benzimidazoles against Pseudomonas aeruginosa.

Journal: International journal of molecular sciences 20090401

Title: Ethyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20080901

Title: Syntheses and structures of two chiral zincophosphite compounds: [Zn(C8H8N2)(HPO3)] and (C6H13N2)[Zn3(C6H12N2)(HPO3)3(H2PO3)].

Journal: Dalton transactions (Cambridge, England : 2003) 20080421

Title: 1,1'-(4-Oxoheptane-1,7-di-yl)bis-(2-methyl-1H-benzimidazole) penta-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Synthesis and inhibitory activity of new benzimidazole derivatives against Burkitt's lymphoma promotion.

Journal: Bioorganic & medicinal chemistry 20071001

Title: Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues.

Journal: Bioorganic & medicinal chemistry 20070601

Title: Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study.

Journal: Bioorganic & medicinal chemistry 20070115

Title: (Glycylglycinato-kappa3O,N,N')(2-methyl-1H-benzimidazole-kappaN3)copper(II) trihydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20060601

Title: Metabolism of pantoprazole involving conjugation with glutathione in rats.

Journal: The Journal of pharmacy and pharmacology 20050301

Title: Induced fit process in the selective distal binding of imidazoles in zinc(II) porphyrin receptors.

Journal: Inorganic chemistry 20030616

Title: Heteroaromatic annulation of 2-methyl/2-cyanomethylbenzimidazole dianions with alpha-oxoketene dithioacetals: a highly regioselective synthetic protocol for 1,2- and 2,3-substituted/annulated pyrido[1,2-a]benzimidazoles.

Journal: The Journal of organic chemistry 20030502

Title: Preparation of highly substituted 4-aminopyridones via the reaction of 2-methylene dihydrobenzimidazole with vinyl isocyanates.

Journal: Organic letters 20030403

Title: Implication of P450-metabolite complex formation in the nonlinear pharmacokinetics and metabolic fate of (+/-)-(1'R*,3R*)-3-phenyl-1-[(1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021001

Title: Synthesis and antiparasitic activity of 1H-benzimidazole derivatives.

Journal: Bioorganic & medicinal chemistry letters 20020819

Title: Formation of mu-oxo dimer by the reaction of (meso-tetraphenylporphyrinato)iron(III) with various imidazoles.

Journal: Journal of inorganic biochemistry 20010301

Title: Synthesis and preliminary antimicrobial screening of new benzimidazole heterocycles.

Journal: Archives of pharmacal research 20010201

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